EKS-RAN-00464

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-RAN-00464

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/CK1	503.1	1.7E-151	17	277	261

Status

Unreviewed

Ensembl Protein

ENSRNOP00000062327

UniProt Accession

D3ZRE3;

Protein Name

Protein Synonyms/Alias

Casein kinase I isoform alpha;

Gene Name

Csnk1a1

Gene Synonyms/Alias

Csnk1a1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSRNOG00000017106	ENSRNOP00000062327	ENSRNOT00000066133
ENSRNOG00000017106	ENSRNOP00000051516	ENSRNOT00000044346

Organism

Rattus norvegicus

Functional Description

Protein Length

337

Protein Sequence
(FASTA)

MASSSGSKAE FIVGGKYKLV RKIGSGSFGD IYLAINITNG EEVAVKLESQ KARHPQLLYE 60

SKLYKILQGG VGIPHIRWYG QEKDYNVLVM DLLGPSLEDL FNFCSRRFTM KTVLMLADQM 120

ISRIEYVHTK NFIHRDIKPD NFLMGIGRHC NKLFLIDFGL AKKYRDNRTR QHIPYREDKN 180

LTGTARYASI NAHLGIEQSR RDDMESLGYV LMYFNRTSLP WQGLKAATKK QKYEKISEKK 240

MSTPVEVLCK GFPAEFAMYL NYCRGLRFEE APDYMYLRQL FRILFRTLNH QYDYTFDWTM 300

LKQKAAQQAA SSSGQGQQAQ TPTGKQTDKT KSNMKGF 337

Nucleotide Sequence
(FASTA)

ATGGCGAGCA GCAGCGGCTC CAAGGCCGAA TTTATCGTCG GTGGGAAATA CAAACTGGTG 60

CGGAAGATCG GATCTGGTTC CTTCGGGGAC ATTTATCTAG CGATCAACAT CACCAATGGC 120

GAGGAAGTGG CAGTGAAACT AGAATCCCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 180

AGCAAACTGT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CTCACATACG GTGGTATGGG 240

CAAGAAAAAG ACTATAATGT GCTAGTCATG GATCTTCTGG GACCCAGCCT CGAAGACCTC 300

TTCAATTTCT GTTCAAGAAG GTTCACTATG AAGACTGTAC TTATGTTAGC TGACCAGATG 360

ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 420

AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTTAT TCCTTATTGA TTTTGGTTTG 480

GCCAAAAAGT ACAGAGACAA CAGGACAAGG CAACACATAC CATACAGGGA AGATAAAAAC 540

CTCACTGGCA CTGCCCGGTA TGCCAGCATC AATGCACATC TTGGCATTGA GCAGAGTCGC 600

CGAGATGACA TGGAATCTTT AGGATATGTT TTGATGTATT TTAATAGAAC CAGTCTGCCA 660

TGGCAAGGGC TAAAGGCTGC AACAAAGAAA CAAAAATATG AAAAGATTAG TGAAAAGAAG 720

ATGTCCACTC CTGTTGAAGT TTTGTGTAAG GGGTTTCCTG CAGAATTTGC CATGTACTTA 780

AATTACTGTC GTGGGCTGCG CTTTGAGGAA GCTCCGGATT ACATGTATCT GAGGCAGCTG 840

TTCCGCATCC TCTTCAGGAC CCTGAACCAC CAGTATGACT ACACGTTTGA TTGGACGATG 900

TTAAAGCAGA AAGCAGCCCA GCAGGCAGCC TCTTCCAGTG GGCAGGGTCA GCAGGCCCAA 960

ACCCCCACAG GCAAGCAAAC TGACAAAACC AAGAGTAACA TGAAAGGTTT CTAA 1014

Domain Profile

S: 1     yrvvkkiGsGsfGdiylgknlasgeevaikleskkskapqlklesrvykilqggvgiPev  60

         y++v+kiGsGsfGdiyl++n+++geeva+kles+k+++pql +es++ykilqggvgiP++

Q: 17    YKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHI  76

         89**********************************************************

S: 61    ryfgkekkynvlvldllGpsledlfdlcerkfslktvllladqlisrieyvhskeliyrd  120

         r++g+ek+ynvlv+dllGpsledlf++c+r+f++ktvl+ladq+isrieyvh+k++i+rd

Q: 77    RWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRD  136

         ************************************************************

S: 121   ikPdnfllgigrkgkkvylidfGlakkyrdaktkkhipyreeksltGtaryasinthlgk  180

         ikPdnfl+gigr+++k++lidfGlakkyrd++t++hipyre+k+ltGtaryasin+hlg+

Q: 137   IKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGI  196

         ************************************************************

S: 181   eqsrrddleslgyvllyflrgslPWqglkaatkkqkyekisekklstsievlcegfPeef  240

         eqsrrdd+eslgyvl+yf+r+slPWqglkaatkkqkyekisekk+st++evlc+gfP+ef

Q: 197   EQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEF  256

         ************************************************************

S: 241   atylkyvrklkfeekPdyeyl  261

         a+yl+y+r l+fee+Pdy+yl

Q: 257   AMYLNYCRGLRFEEAPDYMYL  277

         *******************97

Domain Sequence
(FASTA)

YKLVRKIGSG SFGDIYLAIN ITNGEEVAVK LESQKARHPQ LLYESKLYKI LQGGVGIPHI 60

RWYGQEKDYN VLVMDLLGPS LEDLFNFCSR RFTMKTVLML ADQMISRIEY VHTKNFIHRD 120

IKPDNFLMGI GRHCNKLFLI DFGLAKKYRD NRTRQHIPYR EDKNLTGTAR YASINAHLGI 180

EQSRRDDMES LGYVLMYFNR TSLPWQGLKA ATKKQKYEKI SEKKMSTPVE VLCKGFPAEF 240

AMYLNYCRGL RFEEAPDYMY L 261

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tupaia belangeri"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0005847	; C:mRNA cleavage and polyadenylation specificity factor complex
GO:0016607	; C:nuclear speck
GO:0030529	; C:ribonucleoprotein complex
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0000902	; P:cell morphogenesis

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013