EKS-RAN-00060

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-RAN-00060

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	380.4	6.2E-114	80	365	286

Status

Unreviewed

Ensembl Protein

ENSRNOP00000039105

UniProt Accession

D4A3G2;

Protein Name

Protein Synonyms/Alias

Protein RGD1566355;

Gene Name

RGD1566355

Gene Synonyms/Alias

RGD1566355;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSRNOG00000017213	ENSRNOP00000039105	ENSRNOT00000050188

Organism

Rattus norvegicus

Functional Description

Protein Length

436

Protein Sequence
(FASTA)

VKMKTEKMRT TSWLFQSRDL TEILGTVMKE KKKLVRGHRR AAPLPRDYVP DSPALSPIEL 60

KQELPKYLPA LQGCRSVEEF QCLNRIEEGT YGVVYRAKDK KTDEIVALKR LKMEKEKEGF 120

PITSLREINT ILKAQHPNIV TVREIVVGSN MDKIYIVMNY VEHDLKSLME TMKQPFLPGE 180

VKTLMIQLLS GVKHLHDNWI LHRDLKTSNL LLSHAGILKV GDFGLAREYG SPLKAYTPVV 240

VTLWYRAPEL LLGAKEYSTA VDMWSVGCIF GELLTQKPLF PGKSEIDQIN KVFKDLGTPS 300

EKIWPGYNDL PAVKKMTFSE YPYNNLRKRF GALLSDQGFD LMNKFLTYFP GRRVSAEDGL 360

KHEYFRETPL PIDSSMFPTW PAKSEQQRVK RGTSPRPPEG GLGYSQLGDD DLKETGFHLT 420

TTNQGASCWP WFSLKF 436

Nucleotide Sequence
(FASTA)

GTGAAGATGA AGACAGAGAA AATGAGAACC ACATCTTGGT TGTTCCAGAG TCGCGATTTG 60

ACCGAGATTC TGGGGACAGT GATGAAGGAG AAGAAGAAGT TGGTGAGGGG ACACCGCAGA 120

GCAGCGCCCC TACCGAGGGA CTATGTGCCC GACTCTCCAG CTCTGTCACC TATTGAGCTA 180

AAACAAGAGC TGCCCAAGTA CCTGCCAGCC CTGCAGGGAT GCCGGAGTGT AGAGGAGTTT 240

CAGTGTCTGA ACAGGATTGA AGAAGGCACC TATGGGGTGG TCTACAGAGC AAAGGACAAG 300

AAAACAGATG AGATTGTGGC TCTGAAGCGG TTAAAGATGG AGAAGGAGAA GGAAGGCTTC 360

CCAATCACAT CACTGAGGGA AATCAACACC ATCCTCAAGG CCCAGCACCC CAATATCGTC 420

ACTGTCAGAG AAATTGTTGT GGGAAGCAAC ATGGACAAGA TCTACATTGT GATGAACTAT 480

GTGGAACACG ACCTCAAGAG CCTAATGGAG ACAATGAAAC AGCCCTTCCT GCCAGGGGAG 540

GTGAAGACCC TGATGATTCA GCTGTTGAGT GGGGTGAAGC ACCTCCATGA CAATTGGATC 600

CTACATCGTG ACCTTAAGAC CTCTAACCTT CTGCTGAGCC ATGCTGGCAT TCTCAAGGTG 660

GGCGACTTTG GGCTGGCTCG GGAGTATGGT TCACCCCTAA AGGCCTACAC TCCAGTTGTT 720

GTAACCCTGT GGTATCGTGC CCCAGAACTG CTCCTTGGTG CTAAGGAATA CTCCACAGCT 780

GTGGACATGT GGTCAGTGGG CTGCATATTT GGAGAACTGC TGACACAGAA ACCTCTGTTC 840

CCTGGGAAGT CAGAGATTGA TCAGATTAAC AAGGTTTTCA AGGACCTGGG GACCCCCAGT 900

GAGAAAATCT GGCCTGGCTA TAATGACCTC CCAGCCGTCA AGAAGATGAC CTTCAGCGAG 960

TATCCCTATA ACAACCTCCG CAAGCGATTC GGAGCTTTGT TATCAGATCA AGGATTCGAT 1020

CTCATGAACA AGTTTCTGAC TTACTTCCCT GGGAGGAGGG TCAGCGCAGA AGATGGCCTC 1080

AAGCACGAGT ATTTCCGAGA GACTCCCCTC CCCATCGACT CATCCATGTT CCCCACGTGG 1140

CCTGCCAAGA GTGAGCAGCA GAGGGTGAAG AGAGGCACGA GTCCGAGGCC CCCTGAGGGC 1200

GGCCTGGGCT ACAGCCAGCT GGGAGACGAC GACCTGAAGG AGACGGGCTT CCACCTCACC 1260

ACCACCAACC AGGGAGCCAG CTGCTGGCCC TGGTTCAGCC TCAAGTTCTG A 1311

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         +++l++i+eGtyg+vy+akdk+t+e+vAlK++++ekekeg+pit+lrEi+++ + +h+ni

Q: 80    FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI  139

         7899********************************************************

S: 61    vkLlevva.kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         v++ e+v+ ++ +k+y+v++++e+dLk+l++++k+  + + evk+l++qll+g+++lH+n

Q: 140   VTVREIVVgSNMDKIYIVMNYVEHDLKSLMETMKQ-PFLPGEVKTLMIQLLSGVKHLHDN  198

         *******95666***********************.9999********************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYs  179

         +ilHRDlK++NlL+s+ g+lk++DfGlar+++splk+yt++vvTlwYraPelLlgakeYs

Q: 199   WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS  258

         ************************************************************

S: 180   tavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksf  238

         tavD+Wsvgci+ ellt+kplf+gkseidq++++fk lgtpsek+wp++++lp +k ++f

Q: 259   TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYNDLPAVKkMTF  318

         ********************************************************99**

S: 239   pkkkkkklkekvkklkek.aldllekllaldpkkRisakealqhkyf  284

         +++++++l++++ +l ++ ++dl++k+l++ p +R+sa++ l+h+yf

Q: 319   SEYPYNNLRKRFGALLSDqGFDLMNKFLTYFPGRRVSAEDGLKHEYF  365

         ************8877554***************************9

Domain Sequence
(FASTA)

FQCLNRIEEG TYGVVYRAKD KKTDEIVALK RLKMEKEKEG FPITSLREIN TILKAQHPNI 60

VTVREIVVGS NMDKIYIVMN YVEHDLKSLM ETMKQPFLPG EVKTLMIQLL SGVKHLHDNW 120

ILHRDLKTSN LLLSHAGILK VGDFGLAREY GSPLKAYTPV VVTLWYRAPE LLLGAKEYST 180

AVDMWSVGCI FGELLTQKPL FPGKSEIDQI NKVFKDLGTP SEKIWPGYND LPAVKKMTFS 240

EYPYNNLRKR FGALLSDQGF DLMNKFLTYF PGRRVSAEDG LKHEYF 286

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006915	; P:apoptotic process
GO:0001824	; P:blastocyst development
GO:0007088	; P:regulation of mitosis

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013