| Tag | Content |
|---|
| EKPD ID | EPS-RAN-00013 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 144.7 | 2.3E-42 | 5 | 141 | 137 |
|
| Status | Unreviewed |
| Ensembl Protein | ENSRNOP00000024587 |
| UniProt Accession | D3ZC16; |
| Protein Name | |
| Protein Synonyms/Alias | Dual specificity phosphatase 22 (Predicted), isoform CRA_a; Protein Dusp22; |
| Gene Name | Dusp22 |
| Gene Synonyms/Alias | Dusp22; Dusp22_predicted; rCG_43910; |
| Ensembl Information | |
| Organism | Rattus norvegicus |
| Functional Description | |
| Protein Length | 184 |
Protein Sequence
(FASTA) | | MGSGMSQILP GLYIGNFKDA RDAEQLSRNK VTHILSVHDT ARPMLEGVKY LCIPAADSPS 60 | | QNLTRHFKES IKFIHECRLQ GEGCLVHCLA GVSRSVTLVI AYIMTVTDFG WEEALHTVRA 120 | | GRSCANPNLG FQRQLQEFEK HEVRQYRQWL REEYGENPLR DAEEAKSILA APGILKYWAF 180 | | LRRL 184 |
|
Nucleotide Sequence
(FASTA) | | ATGGGGAGTG GGATGAGCCA GATCCTGCCG GGCCTGTACA TTGGCAACTT CAAAGATGCA 60 | | AGAGATGCAG AACAATTGAG CAGGAACAAG GTGACACACA TTCTTTCTGT GCACGACACT 120 | | GCCAGGCCCA TGCTGGAGGG AGTTAAATAC CTGTGTATTC CAGCAGCAGA CTCACCGTCT 180 | | CAAAACCTGA CAAGACATTT CAAAGAAAGT ATTAAATTCA TTCATGAGTG CCGACTCCAG 240 | | GGTGAGGGCT GTCTTGTACA TTGCCTGGCT GGGGTCTCCA GGAGTGTGAC ACTGGTGATC 300 | | GCATACATCA TGACTGTCAC CGACTTTGGC TGGGAAGAGG CCTTACACAC CGTTCGTGCA 360 | | GGGAGGTCCT GTGCCAACCC CAACCTGGGC TTCCAAAGGC AGCTGCAGGA GTTTGAGAAA 420 | | CACGAAGTGC GGCAGTATCG GCAATGGCTG AGAGAAGAAT ATGGAGAGAA CCCCTTGCGG 480 | | GATGCAGAAG AAGCCAAAAG CATTCTGGCT GCCCCGGGAA TTCTGAAGTA CTGGGCCTTT 540 | | CTCAGAAGAC TGTAA 555 |
|
| Domain Profile | S: 2 vteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvd 61 | +++ilpgly+g+ ++a d +Ls++++t+++ + + + P + +g++y+ ip+ | Q: 5 MSQILPGLYIGNFKDARDAEQLSRNKVTHILSVHDT-AR----P---MLEGVKYLCIPAA 56 | 589***********************9999976544.44....2...459********** |
| S: 62 DsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAie 121 | Ds++++l ++f+e ++fi+e++ +g+ +lvHC aGvsRS+tlv+aY+m+v+++ +++A++ | Q: 57 DSPSQNLTRHFKESIKFIHECRLQGEGCLVHCLAGVSRSVTLVIAYIMTVTDFGWEEALH 116 | ************************************************************ |
| S: 122 avkrkrpsiepnegfleQLlelekk 146 | +v++ r++++pn gf +QL e+ek+ | Q: 117 TVRAGRSCANPNLGFQRQLQEFEKH 141 | ***********************96 |
|
Domain Sequence
(FASTA) | | MSQILPGLYI GNFKDARDAE QLSRNKVTHI LSVHDTARPM LEGVKYLCIP AADSPSQNLT 60 | | RHFKESIKFI HECRLQGEGC LVHCLAGVSR SVTLVIAYIM TVTDFGWEEA LHTVRAGRSC 120 | | ANPNLGFQRQ LQEFEKH 137 |
|
| Keyword | Complete proteome; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | | GO:0008138 | ; F:protein tyrosine/serine/threonine phosphatase activity | | GO:0000122 | ; P:negative regulation of transcription from RNA polymerase II promoter | | GO:0046330 | ; P:positive regulation of JNK cascade | | GO:0006470 | ; P:protein dephosphorylation | | GO:0042127 | ; P:regulation of cell proliferation | | GO:0007179 | ; P:transforming growth factor beta receptor signaling pathway |
|
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |