EKS-RAN-00163

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-RAN-00163

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TTK	491.3	9.1E-148	503	769	267

Status

Unreviewed

Ensembl Protein

ENSRNOP00000042156

UniProt Accession

D3ZSS9;

Protein Name

Protein Synonyms/Alias

Protein Ttk;

Gene Name

Ttk

Gene Synonyms/Alias

Ttk;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSRNOG00000029055	ENSRNOP00000042156	ENSRNOT00000051612

Organism

Rattus norvegicus

Functional Description

Protein Length

835

Protein Sequence
(FASTA)

MEAEELIGRN LTIDSIMNKV RDIKNKINED LTDELNSIKV CVDPTETVNQ IMMVENTPEN 60

WLNFLLKLEK NSPPLNDALL NKLIGRYSQA IEALPPDKYG QNESFARIQV RLAELKAIQE 120

PDDAHDYFQM ARENCKKFAF VHVSFAQFEL SQGNLKKSEQ LLHKAVETGA VPLQMLETAI 180

RNLHLQKKQL LSEEDKKSLS ASTVLTAQES FSSSLGNLQS RKSSCDPKVQ AAAARILYGE 240

NMPPKDAEVS HRNPLKQTNK TKRSCPFGRV PVNLLNSPDY YVKTDGSAVP QFTKRKISGS 300

EYRDSIMPGS KSSGNDSYEL RGLKPIQAIH LKDSLVSNEK SSELMSDLVT LKSKTDSSLT 360

KLEEPKVRQE PEIPERRHKQ WQSARKPGCG IQNSAAFAPQ WHVPDVTPKA DKESPPLSVP 420

KWIDPKSVCE TPSSSSLDDY MKCFKTSVVK NEFPPACPSS TPYSQLARHQ QHQQQGLSTP 480

LQNLQISGSS SMSECISVNG RIYSILKQIG SGGSSKVFQV LNEKKQINAI KYVNLEDADS 540

QTIDSYRNEI AYLNKLQQHS DKIIRLYDYE ITDRYIYMVM ECGNIDLNSW LKKKKSINPW 600

ERKSYWKNML EAVHTIHQHG IVHSDLKPAN FLIVDGMLKL IDFGIANQMQ PDTTSIVKDS 660

QVGTVNYMAP EAIRDMSSSR ENGKIKTKIS PRSDVWSLGC ILYYMTYGKT PFQHIINQVS 720

KLHAIIDPSH EIEFPEISEK DLRDVLKCCL VRNPKERISI PELLAHPYVQ IQPHPGSQMA 780

KETTDEMKYM LGQLVCLNSP NSILKAAKTL YERYNCGESQ APSSSKTSDK KRERE 835

Nucleotide Sequence
(FASTA)

ATGGAGGCTG AAGAGTTAAT TGGCAGAAAT TTGACAATTG ATTCCATCAT GAACAAAGTG 60

AGAGACATTA AAAATAAGAT AAATGAAGAC CTTACTGATG AGCTAAACTC GATCAAAGTC 120

TGTGTTGACC CCACAGAAAC TGTTAACCAA ATTATGATGG TTGAGAACAC ACCAGAGAAC 180

TGGTTGAATT TCTTGCTGAA ACTAGAGAAA AACAGCCCAC CTCTAAACGA TGCTCTTTTA 240

AATAAGCTGA TTGGTCGGTA TAGTCAAGCC ATTGAAGCAC TTCCTCCAGA TAAATATGGC 300

CAGAATGAGA GCTTTGCTCG AATACAAGTG AGACTTGCAG AATTAAAGGC TATTCAAGAA 360

CCTGACGATG CTCACGACTA CTTCCAAATG GCCCGAGAGA ACTGCAAGAA GTTTGCTTTC 420

GTGCATGTCT CTTTCGCACA GTTTGAACTG TCTCAAGGCA ATCTTAAGAA AAGCGAACAG 480

CTTCTTCATA AAGCTGTAGA GACGGGGGCA GTGCCGCTGC AGATGCTGGA GACTGCCATC 540

CGTAACCTAC ACCTCCAGAA AAAGCAGCTG CTCTCAGAGG AGGACAAAAA GAGTTTATCA 600

GCATCTACAG TACTAACTGC CCAAGAATCA TTCTCCAGTT CACTTGGGAA TTTACAGAGT 660

AGGAAGAGCA GCTGCGATCC CAAAGTACAG GCTGCTGCAG CCAGGATTTT ATATGGGGAG 720

AACATGCCTC CAAAAGATGC GGAAGTAAGT CATCGAAATC CCTTAAAGCA AACTAACAAA 780

ACTAAACGGT CATGCCCCTT TGGAAGAGTC CCAGTTAATC TTCTAAATAG CCCAGATTAC 840

TATGTGAAGA CAGATGGTTC AGCTGTGCCA CAGTTTACAA AAAGAAAAAT ATCTGGATCA 900

GAATACCGAG ATTCGATTAT GCCTGGATCC AAATCAAGTG GAAATGATTC CTATGAATTG 960

AGAGGTTTAA AGCCCATTCA AGCTATCCAT TTGAAAGACT CTCTGGTGTC CAATGAAAAA 1020

AGTTCTGAAC TTATGTCTGA TTTAGTAACC TTGAAGAGTA AAACGGATTC AAGTCTAACA 1080

AAGTTGGAAG AACCTAAAGT GCGTCAAGAA CCGGAGATTC CAGAAAGAAG GCACAAGCAG 1140

TGGCAGTCTG CCAGAAAGCC AGGCTGTGGG ATCCAGAACT CGGCTGCCTT TGCCCCCCAG 1200

TGGCACGTTC CAGATGTAAC CCCAAAGGCT GATAAAGAGT CACCACCATT ATCAGTTCCT 1260

AAATGGATTG ATCCAAAGTC TGTCTGTGAG ACACCTAGTA GCAGTTCCTT GGATGATTAC 1320

ATGAAATGTT TTAAGACTTC AGTTGTAAAG AATGAATTCC CACCTGCCTG TCCATCATCA 1380

ACACCTTACA GCCAACTTGC CCGCCACCAG CAGCATCAGC AGCAAGGGCT CAGCACTCCT 1440

CTTCAAAACT TACAGATTTC AGGATCCTCA TCAATGAGTG AATGCATTTC AGTTAACGGA 1500

AGAATTTATT CCATATTAAA ACAGATAGGC AGTGGAGGTT CAAGTAAGGT GTTTCAGGTA 1560

TTGAATGAGA AGAAACAGAT AAACGCTATC AAATACGTGA ACCTTGAAGA CGCAGATAGC 1620

CAAACTATTG ACAGCTACCG CAATGAGATA GCTTACTTGA ACAAGTTACA GCAGCACAGT 1680

GATAAGATCA TCCGCCTCTA TGACTATGAA ATCACGGATC GGTACATCTA CATGGTGATG 1740

GAATGTGGAA ACATTGACCT GAACAGTTGG CTTAAAAAGA AGAAATCCAT CAATCCATGG 1800

GAACGCAAGA GCTACTGGAA AAACATGTTG GAGGCCGTAC ACACGATCCA TCAACATGGC 1860

ATTGTTCATA GTGATCTCAA GCCTGCTAAC TTTCTAATAG TTGACGGAAT GCTAAAGCTA 1920

ATTGATTTTG GGATTGCAAA CCAAATGCAG CCAGATACAA CAAGCATTGT TAAAGATTCT 1980

CAGGTTGGCA CAGTAAACTA CATGGCCCCA GAAGCAATCA GAGACATGTC TTCTTCAAGA 2040

GAAAATGGGA AAATCAAGAC CAAGATAAGT CCCAGAAGTG ATGTGTGGTC CTTGGGGTGC 2100

ATTTTGTACT ATATGACCTA CGGGAAAACA CCATTTCAGC ATATCATTAA TCAGGTCTCT 2160

AAACTACATG CCATAATTGA CCCTAGTCAT GAAATTGAGT TTCCTGAGAT TTCAGAAAAA 2220

GATCTTCGAG ATGTGCTAAA GTGCTGCCTA GTACGGAACC CTAAAGAGAG GATATCTATC 2280

CCCGAGCTCC TCGCACATCC ATATGTTCAG ATTCAGCCCC ATCCAGGCAG CCAAATGGCT 2340

AAGGAGACCA CTGATGAGAT GAAATATATG TTGGGTCAAC TTGTTTGCCT GAATTCTCCT 2400

AACTCCATCC TGAAAGCTGC GAAAACCTTG TATGAACGTT ATAATTGTGG TGAAAGTCAA 2460

GCTCCTTCAT CATCCAAGAC TTCTGACAAA AAGAGAGAAA GAGAGTGA 2508

Domain Profile

S: 1     yeilkklGsGGsskvfkvksekkrvyalkvvdleaaddqtidgykneielleklqdqs.k  59

         y+ilk++GsGGsskvf+v++ekk+++a+k+v+le+ad+qtid+y+nei++l+klq++s k

Q: 503   YSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIDSYRNEIAYLNKLQQHSdK  562

         99********************************************************9*

S: 60    virlydyeledsllylvmecGdidlnkilkkkksiepdyelvsyykemleavkvihqhGi  119

         +irlydye++d ++y+vmecG+idln++lkkkksi+p +e++sy+k+mleav++ihqhGi

Q: 563   IIRLYDYEITDRYIYMVMECGNIDLNSWLKKKKSINP-WERKSYWKNMLEAVHTIHQHGI  621

         *************************************.**********************

S: 120   vhsdlkPanfllvdGilklidfGianavaedttsivkesqvGtvnylaPealkdmsssqs  179

         vhsdlkPanfl+vdG+lklidfGian++++dttsivk+sqvGtvny+aPea++dmsss

Q: 622   VHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSS--  679

         **********************************************************..

S: 180   sereaekskikvsrksdvwslGcilylllygktPfgsirnqvskllaiinPdveiefPei  239

           re++k+k+k+s++sdvwslGcily+++ygktPf++i+nqvskl+aii+P++eiefPei

Q: 680   --RENGKIKTKISPRSDVWSLGCILYYMTYGKTPFQHIINQVSKLHAIIDPSHEIEFPEI  737

         ..**********************************************************

S: 240   tsniekslvellkaclkrnPkkrisvdellsspfv  274

         +   ek+l+++lk+cl+rnPk+ris++ell++p+v

Q: 738   S---EKDLRDVLKCCLVRNPKERISIPELLAHPYV  769

         *...*****************************96

Domain Sequence
(FASTA)

YSILKQIGSG GSSKVFQVLN EKKQINAIKY VNLEDADSQT IDSYRNEIAY LNKLQQHSDK 60

IIRLYDYEIT DRYIYMVMEC GNIDLNSWLK KKKSINPWER KSYWKNMLEA VHTIHQHGIV 120

HSDLKPANFL IVDGMLKLID FGIANQMQPD TTSIVKDSQV GTVNYMAPEA IRDMSSSREN 180

GKIKTKISPR SDVWSLGCIL YYMTYGKTPF QHIINQVSKL HAIIDPSHEI EFPEISEKDL 240

RDVLKCCLVR NPKERISIPE LLAHPYV 267

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR011990	; TPR-like_helical.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013