EKS-RAN-00209

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-RAN-00209

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF3	567.5	1.2E-170	1316	1650	335

Status

Unreviewed

Ensembl Protein

ENSRNOP00000061695

UniProt Accession

D4A563;

Protein Name

Protein Synonyms/Alias

Protein RGD1312026; Similar to RIKEN cDNA C230081A13 (Predicted);

Gene Name

RGD1312026

Gene Synonyms/Alias

RGD1312026; RGD1312026_predicted; rCG_58069;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSRNOG00000042519	ENSRNOP00000061695	ENSRNOT00000068658

Organism

Rattus norvegicus

Functional Description

Protein Length

1733

Protein Sequence
(FASTA)

MSACNTFTEH VWKPGECKNC FKPKSLHQLP PDSEKAPITH GSVKTNANHS NNHRVRNTGN 60

FRPPVAKKPT IAVKPTMMVA DGQSVCGELS IQEHCENKPV ILGWNQNRTS LSQKPLNNNS 120

EGDTEGFGSV PQQCANNDRA KTIPNNNGLT EVLKEIAGLD ASPPVRGNET NSRETFLGRI 180

NDCYKRSLER KIPPSCMTGS TKDSQGKHVI LSGSTEVISN EGGRFCYPEF SSGEESEEDV 240

LFSNMEEEHE SWDESDEELL AMEIRMRGQP RFANFRANTL SPVRFFVSKK WNTIPLRNKS 300

LQRICAVDYD DSYDEILNGY EENSGVSYGQ GSIQSTVSSD STSPDSSFTE ESRSETASSL 360

SQKICNGGIS PGNPGNSKDM AETESNSESP PPNNEEKDSS LTSKSPVKVP ETHKAVLALR 420

LQEKDGKIAV QTEKPENKAS TDIAGQAVTI SLVPVEEQTK PYRVVNLEQP LCKPYTVVDV 480

SAAMASEHLG RPKVKGSSST PNSPVTSPAL TPGQINAHLK KSSAIRYQEV WTSSTSPRQK 540

IPKIELSTGG TGPNVPPRKN CHKSAPTSPT ATNISSKTIP VKSPNLSEIK FNSYNNAGMP 600

PFPIIIHDEP SYARSSKNAI KVPIVINPNA YDNLAIYKSF LGTSGELSVK EKTTSVISHT 660

YEEIETESKV SDSTPSKLAD GPPAKGFSSS AERKRGSVAQ KVQEFNNCLN RGQSSPQRSY 720

SSTHSSPAKI QRPTQEPVGK TESAQGSQVP GSSGSTREKA SAVLCQIVAS IQPPQTPPEA 780

PQSSPKACSV DELYAIPPDA DTTKNIPKNT PVRPKSLFTS QSSGEGEAHQ TTESPTTKTQ 840

KDPSTKPVTS PPSKLVTSTQ SEPPPPFPPP RSTSSPYHAS NLLQRHFTNW TKPTSPTRST 900

EAESILHSEG SRRAADAKPK RWISFKSFFR RRKTDEEEEK EKEREKGKLV GLDGTVIHML 960

PPPPVQRHHW FTEAKGESSE KPAIVFMYRC DPDQGHLSVD QSKAGADNGR TEDVLLRNLE 1020

EKKNSHPPSQ IPDKACSRVT HEVAEELSPR DPRTPAVKQD GTSVTPTLPP PDLEREEEKD 1080

ATSDPTDVSP CSATYSNLGQ SRAAMIPPKH PRHPKGALDD AIAFGEKTDQ EVLNASQPTP 1140

PPLPKKMIRA NTEPIPKDLQ KSMESSLCVV ANPTYDIDPN WDASSAGSSV SYELKGLDVE 1200

SYESLERPLH KERPVPSTAN SISSLATLSI KDRFSNSMES LSSRRGLSCR QARSIQKPQR 1260

QALYRGLDSR EEVVGKLRSL HTDALKRLAV KCEDLFMAGQ KDQLRFGVDS WSDFRLTSDK 1320

PCCEAGDAVY YTASYAKDPL SNYAVKICKS KAKESQQYYH SLAVRQSLPV HFNIQQDCGH 1380

FLAEVPNRLL PWEDPNAPEK AEDGNEDSEE EVKAETSGGN PEPCSESESS QKENQQVTNR 1440

KQRSHVVVIT REVPHLTVAD FVRDSLAHHG KSPDLYERQV CLLLLQLCSG LEHLKPYHVT 1500

HCDLRLENLL LVQHQPGGAT QCPSPADPCP TSACPTRLIV SNFSQAKQKS HLMDPQILRD 1560

QSRLAPEIIT ATQYKKCDEF QTGILIYEML HLPNPFDENP ELKEKEYTRT DLPRIPLRSP 1620

YSWGLQQLAS CLLNPNPSER ILISDAKGIL QCLLWGPRED LFQIFTTSAT LVQKNALLQN 1680

WLDIKRTLLM IKFAEKSLDR EGGISLEDWL CAQYLAFATT DSLSYIVKIL QYR 1733

Nucleotide Sequence
(FASTA)

ATGTCTGCTT GTAACACCTT TACTGAACAC GTTTGGAAAC CTGGCGAATG CAAGAATTGC 60

TTTAAACCGA AAAGCTTACA CCAGCTTCCT CCAGACTCTG AGAAGGCGCC CATCACCCAC 120

GGCAGTGTGA AAACTAATGC CAATCACAGT AACAACCACC GAGTCAGGAA CACCGGCAAT 180

TTCCGGCCCC CTGTGGCTAA AAAGCCCACC ATAGCTGTGA AGCCCACTAT GATGGTAGCA 240

GATGGGCAAA GTGTATGCGG TGAGCTAAGC ATCCAGGAAC ACTGTGAGAA CAAGCCTGTC 300

ATCCTGGGGT GGAACCAAAA CAGGACTTCT TTGAGCCAGA AACCACTTAA CAACAATTCT 360

GAAGGTGATA CTGAAGGCTT TGGCAGTGTT CCTCAGCAGT GTGCCAATAA TGACCGTGCA 420

AAAACGATAC CCAACAACAA CGGGCTAACC GAAGTGCTAA AGGAGATAGC GGGTCTGGAC 480

GCCAGCCCTC CCGTCAGAGG AAACGAAACG AACTCCAGAG AAACATTCTT GGGAAGAATA 540

AATGATTGTT ACAAACGATC ATTGGAAAGG AAGATCCCAC CCAGTTGCAT GACCGGGAGC 600

ACGAAGGACT CTCAGGGCAA GCACGTCATT CTGAGTGGGA GCACTGAGGT CATCAGTAAT 660

GAAGGGGGCA GGTTCTGCTA CCCTGAGTTC TCCAGTGGTG AGGAGAGTGA GGAAGACGTG 720

CTTTTCAGTA ACATGGAAGA AGAGCATGAG AGCTGGGACG AGAGCGATGA GGAACTGTTA 780

GCCATGGAGA TTCGCATGAG AGGGCAACCT CGATTTGCCA ACTTCAGGGC AAACACCCTA 840

TCTCCCGTTC GATTCTTTGT GAGCAAAAAG TGGAATACTA TCCCCTTACG GAATAAGTCT 900

CTGCAGAGAA TCTGTGCTGT AGACTATGAC GACAGCTATG ATGAAATCCT GAATGGTTAT 960

GAGGAAAATT CTGGGGTGTC TTATGGTCAA GGAAGCATTC AGAGCACAGT GTCATCTGAT 1020

TCCACATCAC CAGATTCCTC CTTTACTGAA GAGTCACGTT CTGAAACAGC CAGCAGTTTA 1080

TCCCAGAAGA TTTGTAATGG GGGGATATCT CCTGGTAATC CAGGAAATTC TAAAGACATG 1140

GCAGAAACTG AGTCTAATTC TGAAAGTCCT CCTCCTAATA ATGAGGAGAA GGACTCATCA 1200

CTGACTTCCA AAAGCCCAGT GAAAGTTCCA GAGACACACA AAGCCGTCCT CGCTCTCCGC 1260

TTACAGGAGA AGGATGGCAA GATTGCAGTA CAAACCGAGA AGCCAGAGAA CAAAGCTTCT 1320

ACAGATATTG CTGGCCAGGC AGTCACCATA AGCCTCGTCC CAGTAGAAGA ACAGACAAAG 1380

CCCTACCGCG TGGTAAATCT GGAACAGCCA CTGTGTAAGC CATATACAGT TGTGGATGTG 1440

TCGGCAGCAA TGGCCAGCGA GCACCTGGGA CGCCCCAAGG TAAAAGGTTC ATCTTCAACC 1500

CCAAACTCTC CAGTTACATC ACCTGCGTTG ACACCAGGAC AAATAAACGC CCATCTCAAA 1560

AAATCCAGTG CAATCCGTTA CCAGGAAGTG TGGACTTCCA GCACCAGTCC ACGACAAAAG 1620

ATCCCTAAAA TAGAATTAAG TACTGGGGGA ACTGGGCCAA ATGTCCCTCC AAGGAAAAAC 1680

TGCCATAAAT CAGCGCCCAC TTCACCCACG GCTACAAACA TCTCCTCCAA AACCATTCCT 1740

GTTAAGTCAC CTAACTTGTC TGAAATAAAA TTTAATAGTT ACAACAATGC TGGGATGCCA 1800

CCTTTTCCCA TCATCATCCA CGACGAGCCA TCCTATGCCC GGAGTTCCAA AAATGCCATT 1860

AAAGTGCCCA TTGTTATTAA TCCAAATGCA TATGACAATC TCGCCATCTA CAAAAGTTTT 1920

CTGGGAACAA GTGGTGAACT CTCTGTGAAG GAAAAAACTA CAAGCGTAAT AAGCCATACT 1980

TACGAAGAAA TCGAAACTGA GAGCAAAGTG TCTGACAGCA CCCCCAGCAA GCTCGCAGAC 2040

GGCCCCCCGG CTAAAGGGTT TTCTAGCAGT GCAGAACGCA AACGAGGCTC AGTAGCGCAG 2100

AAGGTTCAGG AGTTTAACAA TTGTCTCAAC AGAGGTCAGT CTTCTCCACA AAGAAGCTAC 2160

AGTTCCACCC ACAGCTCCCC AGCAAAAATC CAGAGACCCA CTCAAGAGCC TGTGGGCAAA 2220

ACAGAAAGTG CACAAGGGTC TCAGGTACCG GGCAGCAGTG GCAGCACCAG GGAGAAAGCA 2280

AGTGCCGTCC TATGTCAGAT TGTGGCATCT ATCCAACCCC CCCAGACTCC TCCAGAAGCA 2340

CCTCAGTCTA GCCCTAAGGC TTGCAGTGTG GACGAGCTTT ATGCCATTCC TCCAGATGCA 2400

GATACTACAA AAAATATTCC TAAAAACACA CCAGTCAGAC CCAAATCTCT CTTCACATCT 2460

CAGTCTAGTG GCGAAGGTGA GGCCCATCAG ACCACAGAAA GCCCTACTAC CAAAACTCAG 2520

AAAGATCCAT CCACAAAGCC AGTGACTTCT CCTCCCTCCA AATTAGTGAC CAGCACCCAG 2580

AGTGAGCCAC CGCCTCCCTT TCCCCCACCA CGGTCTACTT CCTCCCCTTA CCATGCAAGT 2640

AACCTGTTGC AGAGGCATTT TACCAATTGG ACAAAGCCAA CCAGTCCCAC CAGATCGACA 2700

GAAGCTGAAT CAATTTTGCA CTCTGAAGGC AGCAGACGAG CAGCTGATGC AAAACCTAAA 2760

CGTTGGATAT CATTTAAAAG CTTCTTCCGC CGCCGGAAAA CTGATGAGGA AGAAGAGAAG 2820

GAGAAAGAGC GAGAGAAAGG GAAGTTGGTG GGCCTGGACG GAACAGTCAT CCACATGCTG 2880

CCGCCCCCTC CAGTCCAGCG CCATCACTGG TTCACAGAGG CAAAAGGAGA GTCCAGTGAG 2940

AAGCCTGCTA TCGTCTTCAT GTACAGGTGT GACCCTGACC AAGGCCACCT CAGTGTGGAC 3000

CAAAGCAAGG CTGGGGCAGA CAATGGAAGG ACAGAGGACG TGTTGCTGCG GAACTTAGAA 3060

GAGAAGAAAA ATAGCCATCC TCCATCTCAG ATTCCTGACA AAGCTTGCAG TCGCGTGACC 3120

CATGAAGTGG CAGAGGAACT TTCTCCTCGG GATCCAAGAA CTCCTGCTGT GAAGCAAGAT 3180

GGCACTTCAG TCACACCAAC ATTGCCTCCA CCTGACCTGG AAAGGGAAGA AGAAAAAGAT 3240

GCCACTTCGG ATCCTACAGA CGTGAGTCCG TGCAGCGCAA CATACAGCAA CTTAGGACAA 3300

TCTAGAGCAG CCATGATACC TCCCAAGCAC CCGCGGCATC CCAAGGGAGC GTTGGATGAT 3360

GCCATTGCCT TTGGAGAGAA GACAGACCAA GAAGTATTGA ATGCTTCCCA ACCCACACCA 3420

CCCCCACTGC CAAAGAAAAT GATACGAGCC AACACAGAGC CAATCCCCAA AGACCTTCAG 3480

AAATCCATGG AAAGCAGTCT CTGCGTCGTG GCTAATCCCA CCTATGATAT TGATCCCAAC 3540

TGGGATGCCA GCAGTGCTGG ATCTTCTGTC AGCTATGAAC TCAAGGGACT GGATGTTGAG 3600

TCTTATGAAT CCTTGGAGAG ACCTTTGCAC AAGGAGAGAC CTGTTCCTTC CACAGCAAAC 3660

AGTATCTCCA GCTTAGCCAC TCTCAGTATT AAGGACAGAT TTTCCAACAG TATGGAGTCA 3720

CTCTCTAGCC GACGTGGTCT CTCCTGTAGA CAGGCTCGAA GCATCCAGAA GCCACAGAGA 3780

CAAGCACTTT ATCGAGGACT TGACAGTCGG GAAGAAGTGG TGGGTAAACT CCGAAGCCTT 3840

CATACAGATG CCTTGAAAAG ACTGGCAGTT AAATGTGAAG ACCTCTTCAT GGCTGGGCAG 3900

AAAGACCAAC TCCGCTTCGG AGTGGACAGC TGGTCAGACT TCAGGCTAAC CAGCGACAAA 3960

CCGTGCTGCG AAGCTGGAGA TGCGGTTTAC TACACTGCCT CATATGCAAA AGATCCACTC 4020

AGTAACTATG CAGTCAAGAT CTGCAAGAGC AAAGCGAAGG AGTCGCAGCA GTATTACCAT 4080

AGCCTGGCTG TCCGGCAGAG TCTGCCTGTA CATTTTAACA TCCAGCAGGA TTGTGGCCAT 4140

TTCCTTGCTG AAGTCCCTAA TCGTCTGCTT CCCTGGGAGG ATCCCAATGC TCCTGAAAAG 4200

GCAGAGGATG GCAATGAAGA CAGTGAGGAA GAGGTGAAGG CAGAAACTTC AGGGGGAAAT 4260

CCTGAGCCCT GCTCTGAATC AGAGTCATCC CAGAAAGAGA ACCAACAAGT CACAAACAGG 4320

AAGCAAAGAA GCCATGTCGT GGTCATCACC AGGGAGGTTC CCCATCTCAC TGTGGCCGAC 4380

TTCGTGCGAG ACTCTTTGGC ACATCATGGG AAAAGCCCCG ACTTGTATGA GAGGCAAGTG 4440

TGTCTGCTGC TCTTACAGCT GTGCTCTGGT CTTGAGCACC TCAAGCCCTA CCACGTCACT 4500

CACTGCGATC TTCGCCTGGA GAACTTGCTG CTTGTCCAGC ACCAACCTGG GGGAGCCACC 4560

CAGTGCCCTT CACCTGCAGA CCCCTGCCCC ACCTCAGCTT GTCCCACAAG ACTCATTGTG 4620

AGTAACTTTT CTCAGGCCAA ACAGAAGAGC CATCTGATGG ACCCTCAGAT CCTCCGAGAC 4680

CAGTCCCGCC TTGCCCCAGA GATCATCACG GCCACCCAGT ATAAAAAGTG TGATGAATTC 4740

CAGACAGGCA TCCTCATCTA TGAGATGCTG CACCTGCCCA ACCCTTTTGA TGAGAACCCA 4800

GAGCTGAAGG AGAAGGAGTA CACGCGCACA GACCTGCCTC GGATCCCTCT CCGCTCCCCG 4860

TACTCTTGGG GCCTGCAGCA ACTTGCCAGC TGTCTCCTGA ACCCCAACCC TTCTGAGCGC 4920

ATCCTCATTT CTGACGCCAA AGGCATCCTC CAGTGTCTGC TCTGGGGCCC CCGAGAAGAT 4980

CTCTTCCAAA TCTTCACCAC CTCGGCAACC CTAGTACAGA AGAACGCTCT CCTCCAAAAC 5040

TGGCTGGACA TCAAGCGAAC ACTGCTGATG ATCAAGTTTG CCGAGAAGTC CCTGGACAGA 5100

GAGGGGGGCA TCAGCCTTGA AGATTGGCTT TGTGCTCAGT ATCTGGCCTT TGCCACCACA 5160

GACTCCCTGA GCTACATTGT AAAAATCCTG CAGTACCGTT AA 5202

Domain Profile

S: 1     ltsdkpcceagdavyytasyakdplsnyavkickskekksqsy.....vrqslpvhfniq  55

         ltsdkpcceagdavyytasyakdplsnyavkicksk+k+sq+y     vrqslpvhfniq

Q: 1316  LTSDKPCCEAGDAVYYTASYAKDPLSNYAVKICKSKAKESQQYyhslaVRQSLPVHFNIQ  1375

         79**********************************************************

S: 56    qdcGhflaevpsrlla..dpdapekd...................pkpasetepsake..  92

         qdcGhflaevp+rll+  dp+apek+                   p+p+se+e+s+ke

Q: 1376  QDCGHFLAEVPNRLLPweDPNAPEKAedgnedseeevkaetsggnPEPCSESESSQKEnq  1435

         *************************99*********************************

S: 93    .......rdhvvvitrevphltvadfvrdslashraepelyerrvcllllqlcsGlehlk  145

                r+hvvvitrevphltvadfvrdsla+h+++p+lyer+vcllllqlcsGlehlk

Q: 1436  qvtnrkqRSHVVVITREVPHLTVADFVRDSLAHHGKSPDLYERQVCLLLLQLCSGLEHLK  1495

         ************************************************************

S: 146   eygvihrdlrlenlllvhlqpqagaaqaaapaepaptsaapsaapaattasqegprekql  205

         +y+v+h+dlrlenlllv++qp +ga+q+++pa+p+ptsa+p

Q: 1496  PYHVTHCDLRLENLLLVQHQP-GGATQCPSPADPCPTSACP-------------------  1535

         *********************.*******************...................

S: 206   trlivsnflkakqksgglvdlqikkdqarlapeivsasqykkfdefqtGiliyellhlpn  265

         trlivsnf++akqks +l+d+qi++dq+rlapei++a+qykk+defqtGiliye+lhlpn

Q: 1536  TRLIVSNFSQAKQKS-HLMDPQILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPN  1594

         9**************.********************************************

S: 266   pfevraelkereyrredlprlpllslysrGlqqlasllleadpikriliseakrvl  321

         pf++++elke+ey+r+dlpr+pl+s+ys+Glqqlas+ll+++p++rilis+ak++l

Q: 1595  PFDENPELKEKEYTRTDLPRIPLRSPYSWGLQQLASCLLNPNPSERILISDAKGIL  1650

         ******************************************************98

Domain Sequence
(FASTA)

LTSDKPCCEA GDAVYYTASY AKDPLSNYAV KICKSKAKES QQYYHSLAVR QSLPVHFNIQ 60

QDCGHFLAEV PNRLLPWEDP NAPEKAEDGN EDSEEEVKAE TSGGNPEPCS ESESSQKENQ 120

QVTNRKQRSH VVVITREVPH LTVADFVRDS LAHHGKSPDL YERQVCLLLL QLCSGLEHLK 180

PYHVTHCDLR LENLLLVQHQ PGGATQCPSP ADPCPTSACP TRLIVSNFSQ AKQKSHLMDP 240

QILRDQSRLA PEIITATQYK KCDEFQTGIL IYEMLHLPNP FDENPELKEK EYTRTDLPRI 300

PLRSPYSWGL QQLASCLLNP NPSERILISD AKGIL 335

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0015629	; C:actin cytoskeleton
GO:0005925	; C:focal adhesion
GO:0005524	; F:ATP binding
GO:0004715	; F:non-membrane spanning protein tyrosine kinase activity
GO:0016477	; P:cell migration
GO:0046777	; P:protein autophosphorylation
GO:0034446	; P:substrate adhesion-dependent cell spreading

KEGG

rno:315686

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

Created Date

20-Feb-2013