| Tag | Content |
|---|
| EKPD ID | EPS-RAN-00018 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 69.9 | 2.4E-19 | 87 | 198 | 112 |
|
| Status | Reviewed |
| Ensembl Protein | ENSRNOP00000054285 |
| UniProt Accession | Q4KM79; |
| Protein Name | RNA/RNP complex-1-interacting phosphatase |
| Protein Synonyms/Alias | Dual specificity protein phosphatase 11; Phosphatase that interacts with RNA/RNP complex 1; |
| Gene Name | Dusp11 |
| Gene Synonyms/Alias | Dusp11; Pir1; |
| Ensembl Information | |
| Organism | Rattus norvegicus |
| Functional Description | Possesses RNA 5'-triphosphatase and diphosphataseactivities, but displays a poor protein-tyrosine phosphatase activity (By similarity). Binds to RNA (By similarity). May participate in nuclear mRNA metabolism (By similarity). |
| Protein Length | 326 |
Protein Sequence
(FASTA) | | MNQWHYGRYS RGRDFTARAP PKKKGKNQIP ERWKDYLPVG QRMPGTRFIA FKVPLQKKFE 60 | | AKLMPEECFS PLDLFNKIQE QNEELGLIID LTYTQRYYKV EDLPKTISYI KILTVGHQVP 120 | | DSGTIFQFKS AVKEFLKRNK NNDKLIGVHC THGLNRTGYL ICRYLIDVEG MRPDDAIELF 180 | | NRCRGHCIER QNYIENLQKR RVRKNQNASA SRSGGLEDSA HLTEQVHTTN KPVNKGPKKS 240 | | RRGGHLESSQ HVQTQSSAYS FRKWSQNQSV YQRGFVPPPG PAGEDYSQRR FFWSMRPNGS 300 | | QATHHKKWIA ASYQRPFYPA SWEWNV 326 |
|
Nucleotide Sequence
(FASTA) | | ATGAACCAGT GGCATTATGG CCGATACAGT CGGGGCCGGG ACTTTACTGC CCGTGCCCCA 60 | | CCCAAGAAGA AGGGCAAAAA CCAGATCCCG GAAAGGTGGA AAGACTATCT CCCAGTTGGG 120 | | CAACGGATGC CTGGGACTCG TTTCATTGCT TTCAAAGTTC CTTTGCAAAA AAAATTTGAA 180 | | GCAAAGCTTA TGCCAGAAGA ATGCTTTTCT CCTTTGGATC TCTTTAATAA AATTCAAGAA 240 | | CAAAATGAAG AACTTGGATT GATAATCGAT TTAACATATA CTCAGCGCTA TTATAAAGTA 300 | | GAGGATTTGC CAAAAACTAT TTCTTACATA AAAATTCTTA CAGTTGGTCA TCAGGTACCT 360 | | GACAGTGGCA CTATTTTTCA GTTCAAAAGT GCAGTTAAAG AGTTTTTAAA GAGAAATAAA 420 | | AACAATGACA AACTTATTGG TGTCCACTGT ACCCATGGCT TAAATAGGAC TGGCTACCTC 480 | | ATTTGCAGAT ATTTGATTGA TGTAGAAGGC ATGAGGCCAG ATGATGCAAT TGAATTGTTC 540 | | AACAGGTGCC GGGGACATTG CATAGAAAGG CAGAACTACA TCGAAAACCT GCAGAAACGT 600 | | CGTGTCAGAA AGAACCAGAA TGCTAGTGCA TCTAGATCAG GTGGTCTTGA AGACTCAGCA 660 | | CATCTTACAG AACAAGTCCA CACCACTAAC AAACCTGTGA ACAAAGGACC TAAGAAAAGC 720 | | CGACGTGGTG GTCATCTGGA ATCGTCCCAG CATGTTCAGA CCCAGAGCTC AGCGTACTCA 780 | | TTCAGAAAAT GGTCACAAAA TCAGAGTGTT TACCAGAGAG GCTTCGTCCC TCCTCCCGGT 840 | | CCAGCTGGAG AGGACTATTC ACAGAGAAGA TTCTTCTGGA GCATGAGACC AAATGGCAGT 900 | | CAAGCAACCC ATCATAAGAA ATGGATTGCT GCTAGTTACC AGAGACCTTT CTACCCAGCC 960 | | TCCTGGGAAT GGAATGTGTG A 981 |
|
| Domain Profile | S: 28 itvvinaslsvikvqviPeylikkgityknipvdDsdvtdllqyfdeaaefideakekgg 87 | + + ++ + kv+ P+ + + + + + d+ ++q+ +++ ef++++k++++ | Q: 87 LIIDLTYTQRYYKVEDLPKTISYI--KILTVGHQVPDSGTIFQFKSAVKEFLKRNKNNDK 144 | 455556666667777777777444..444444444455689******************* |
| S: 88 kvlvHCaaGvsRSatlvlaYLmkveglslsdAieavkrkrpsiepnegfleQLl 141 | + vHC++G++R+++l++ YL++veg++ +dAie ++r+r++++++++++e L | Q: 145 LIGVHCTHGLNRTGYLICRYLIDVEGMRPDDAIELFNRCRGHCIERQNYIENLQ 198 | ***************************************************997 |
|
Domain Sequence
(FASTA) | | LIIDLTYTQR YYKVEDLPKT ISYIKILTVG HQVPDSGTIF QFKSAVKEFL KRNKNNDKLI 60 | | GVHCTHGLNR TGYLICRYLI DVEGMRPDDA IELFNRCRGH CIERQNYIEN LQ 112 |
|
| Keyword | Complete proteome; Hydrolase; Nucleus; Reference proteome; RNA-binding. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |