| Tag | Content |
|---|
| EKPD ID | EPS-RAN-00118 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/PRL | 153.8 | 1.1E-45 | 79 | 145 | 67 |
|
| Status | Reviewed |
| Ensembl Protein | ENSRNOP00000064832 |
| UniProt Accession | Q6P9X4; O88765; |
| Protein Name | Protein tyrosine phosphatase type IVA 2 |
| Protein Synonyms/Alias | Protein-tyrosine phosphatase 4a2; Protein-tyrosine phosphatase of regenerating liver 2; PRL-2; |
| Gene Name | Ptp4a2 |
| Gene Synonyms/Alias | Ptp4a2; Prl2; |
| Ensembl Information | |
| Organism | Rattus norvegicus |
| Functional Description | Protein tyrosine phosphatase which stimulatesprogression from G1 into S phase during mitosis. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB (By similarity). |
| Protein Length | 167 |
Protein Sequence
(FASTA) | | MNRPAPVEIS YENMRFLITH NPTNATLNKF TEELKKYGVT TLVRVCDATY DKAPVEKEGI 60 | | HVLDWPFDDG APPPNQIVDD WLNLLKTKFR EEPGCCVAVH CVAGLGRAPV LVALALIECG 120 | | MKYEDAVQFI RQKRRGAFNS KQLLYLEKYR PKMRLRFRDT NGHCCVQ 167 |
|
Nucleotide Sequence
(FASTA) | | ATGAACCGTC CAGCCCCTGT GGAGATCTCG TACGAGAACA TGCGTTTTCT GATAACTCAC 60 | | AACCCAACCA ATGCGACTCT CAACAAGTTC ACCGAGGAAC TCAAGAAGTA CGGAGTGACA 120 | | ACTTTGGTCC GAGTTTGTGA TGCTACCTAT GACAAAGCTC CAGTTGAAAA AGAAGGGATC 180 | | CACGTTCTAG ACTGGCCATT TGATGACGGA GCTCCGCCCC CTAATCAGAT AGTAGATGAT 240 | | TGGCTAAACC TGTTAAAGAC CAAATTCCGG GAAGAGCCAG GCTGCTGTGT CGCAGTGCAT 300 | | TGTGTTGCAG GATTGGGAAG GGCTCCTGTG CTAGTTGCAC TTGCACTGAT TGAATGCGGA 360 | | ATGAAGTATG AAGATGCTGT TCAGTTTATA AGACAAAAAA GAAGAGGAGC ATTCAATTCC 420 | | AAACAGCTGC TTTACTTGGA GAAATACCGA CCTAAGATGC GATTACGCTT CAGAGATACC 480 | | AACGGGCACT GCTGTGTTCA GTAG 504 |
|
| Domain Profile | S: 1 ddwlslvkikfreepGsciavhcvaGlGrapvlvalaliesGmkyedavqfirqkrrGai 60 | ddwl l+k kfreepG+c+avhcvaGlGrapvlvalalie GmkyedavqfirqkrrGa+ | Q: 79 DDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAF 138 | 8*********************************************************** |
| S: 61 nskqlly 67 | nskqlly | Q: 139 NSKQLLY 145 | ******9 |
|
Domain Sequence
(FASTA) | | DDWLNLLKTK FREEPGCCVA VHCVAGLGRA PVLVALALIE CGMKYEDAVQ FIRQKRRGAF 60 | | NSKQLLY 67 |
|
| Keyword | Cell membrane; Complete proteome; Cytoplasm; Disulfide bond; Endosome; Hydrolase; Lipoprotein; Membrane; Methylation; Prenylation; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | | PS00383 | ; TYR_PHOSPHATASE_1; FALSE_NEG. | | PS50056 | ; TYR_PHOSPHATASE_2; 1. | | PS50055 | ; TYR_PHOSPHATASE_PTP; FALSE_NEG. |
|
| Prints | |
| Created Date | 20-Feb-2013 |