EKS-SOA-00009

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SOA-00009

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	363.2	6.3E-109	186	451	266

Status

Unreviewed

Ensembl Protein

ENSSARP00000008149

Gene Name

IRAK4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSARG00000009003	ENSSARP00000008149	ENSSART00000008999

Organism

Sorex araneus

Protein Length

457

Protein Sequence
(FASTA)

MSKPITPSTY VRCLNVGLIR KLADFIDPQE GWKKLAVAIK KPSGDDRYNQ FHIRRFEALL 60

QTGKSPTSEL LFDWGTTNCT VGDLVDLLVQ NEFFAPASLL LPDAVPKTIS SREAAVVQQT 120

QILLCDKNRT SMIPVQNLEH NHMPSDTSNP EKGSLEMNDT CFYSFSFYEL KNVTNNFDER 180

PISLGGNKMG EGGFGVVYKG FVNNRAIAVK KLVAMVDIST EELKQQFDQE IKVMAKCQHE 240

NLVELLGFSN DGDDLCLVYV YMPNGSLLDR LACLDNTPPL SWHIRCKIAQ GSANGISYLH 300

ENQHIHRDIK SANILLDEVF TAKISDFGLA RASEKITQTV MTSRIVGTTA YMAPEALRGE 360

ITPKSDIYSF GVVLLEIITG LPPVDDHRDP QLLLDIKEEI EDEEKTIDDY IDKKMDDIDS 420

SSIESMYFVA SQCLHEKKNK RPTITKVQEL LQNITAS 457

Nucleotide Sequence
(FASTA)

ATGAGCAAAC CTATAACGCC GTCAACATAT GTGCGCTGCC TGAATGTTGG ATTAATTAGG 60

AAACTAGCAG ATTTTATTGA TCCTCAAGAA GGATGGAAAA AGTTAGCAGT AGCTATTAAA 120

AAACCGTCTG GTGATGATAG ATACAATCAG TTTCACATAA GGAGATTTGA AGCATTACTT 180

CAGACAGGGA AAAGTCCTAC TTCTGAATTA CTGTTTGACT GGGGCACCAC AAATTGCACA 240

GTTGGTGATC TCGTTGATCT TTTGGTCCAA AATGAATTTT TTGCTCCTGC AAGTCTTTTG 300

CTACCAGATG CTGTTCCTAA AACCATTAGT TCTAGAGAAG CTGCCGTAGT TCAGCAGACA 360

CAGATACTTC TCTGTGACAA AAACAGAACA TCTATGATAC CTGTGCAAAA TCTTGAACAC 420

AACCATATGC CATCTGATAC CTCAAATCCA GAAAAAGGAA GTTTAGAAAT GAACGATACA 480

TGTTTTTACA GTTTTTCATT TTATGAATTG AAGAATGTCA CAAATAACTT CGATGAACGA 540

CCCATTTCTC TTGGTGGTAA CAAAATGGGG GAGGGAGGAT TCGGAGTCGT ATACAAAGGC 600

TTTGTGAACA ACAGAGCCAT AGCAGTGAAG AAGCTTGTTG CGATGGTTGA CATTAGTACT 660

GAAGAACTGA AACAACAGTT TGATCAAGAA ATAAAAGTAA TGGCAAAGTG TCAACATGAA 720

AACTTAGTAG AACTGCTTGG TTTCTCGAAT GATGGAGATG ACCTGTGCTT AGTATATGTT 780

TACATGCCTA ATGGTTCATT GCTGGACAGA CTGGCCTGTT TGGATAATAC TCCACCACTT 840

TCATGGCACA TAAGATGCAA GATTGCTCAG GGCTCAGCTA ATGGTATCAG TTATTTACAC 900

GAAAACCAAC ATATTCATAG AGATATTAAA AGTGCAAATA TCTTACTAGA TGAAGTCTTC 960

ACAGCTAAAA TATCTGACTT TGGACTTGCA CGGGCTTCTG AGAAAATTAC CCAAACTGTG 1020

ATGACTAGTA GAATTGTGGG AACAACTGCC TATATGGCAC CTGAAGCTCT TCGAGGAGAA 1080

ATAACACCTA AATCTGACAT CTACAGTTTT GGCGTAGTTT TACTAGAAAT AATAACTGGA 1140

CTTCCACCTG TGGATGATCA TCGTGACCCT CAGTTATTGC TAGATATTAA GGAAGAAATC 1200

GAAGATGAAG AAAAAACTAT AGACGATTAT ATTGATAAGA AGATGGATGA CATTGATTCG 1260

TCTTCCATTG AAAGCATGTA CTTTGTTGCT AGTCAGTGTC TACATGAAAA GAAAAATAAG 1320

CGACCAACTA TTACAAAGGT TCAAGAGCTA CTGCAAAATA TTACAGCATC TTAG 1374

Domain Profile

S: 4     dnrigeGgfgevyrgelkntavavkklkeeadlslkelkqsfltElkvlarfrHdnilel  63

         +n++geGgfg+vy+g ++n a+avkkl +++d+s++elkq+f++E+kv+a+++H+n++el

Q: 186   GNKMGEGGFGVVYKGFVNNRAIAVKKLVAMVDISTEELKQQFDQEIKVMAKCQHENLVEL  245

         69**********************************************************

S: 64    lgysaeseklcLvYqymknGsLedrLqcqkgsepLsWpqRlsillGtaraiefLHeasps  123

         lg+s ++++lcLvY ym+nGsL drL c ++++pLsW++R++i++G a++i++LHe+  +

Q: 246   LGFSNDGDDLCLVYVYMPNGSLLDRLACLDNTPPLSWHIRCKIAQGSANGISYLHEN--Q  303

         *********************************************************..9

S: 124   lihgdiksaNiLLDekltpKlgDfglarfapesekqsstvlrtskvrgtlaYlpeefirv  183

         +ih+diksaNiLLDe +t+K++Dfglar   +sek ++tv+ ts+++gt+aY+++e++r

Q: 304   HIHRDIKSANILLDEVFTAKISDFGLAR---ASEKITQTVM-TSRIVGTTAYMAPEALR-  358

         ****************************...99*******9.*****************.

S: 184   gqltvkvDvySfGiVllEvltGlravdedrktkyLkdllkeeieeekveilekfldkkag  243

         g++t k+D+ySfG+VllE++tGl+ vd++r+++ L+d+ keeie+e+ +++++++dkk+

Q: 359   GEITPKSDIYSFGVVLLEIITGLPPVDDHRDPQLLLDI-KEEIEDEE-KTIDDYIDKKMD  416

         *************************************9.********.9***********

S: 244   kleeellealielalaclaekakkrPtmsqvlell  278

         ++++++ e+++ +a++cl+ek++krPt+++v+ell

Q: 417   DIDSSSIESMYFVASQCLHEKKNKRPTITKVQELL  451

         ********************************986

Domain Sequence
(FASTA)

GNKMGEGGFG VVYKGFVNNR AIAVKKLVAM VDISTEELKQ QFDQEIKVMA KCQHENLVEL 60

LGFSNDGDDL CLVYVYMPNG SLLDRLACLD NTPPLSWHIR CKIAQGSANG ISYLHENQHI 120

HRDIKSANIL LDEVFTAKIS DFGLARASEK ITQTVMTSRI VGTTAYMAPE ALRGEITPKS 180

DIYSFGVVLL EIITGLPPVD DHRDPQLLLD IKEEIEDEEK TIDDYIDKKM DDIDSSSIES 240

MYFVASQCLH EKKNKRPTIT KVQELL 266

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>