EKS-SAH-00086

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00086

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	415.2	2.3E-124	439	766	328

Status

Unreviewed

Ensembl Protein

ENSSHAP00000000364

UniProt Accession

G3VB09;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000000321	ENSSHAP00000000364	ENSSHAT00000000369
ENSSHAG00000000321	ENSSHAP00000000363	ENSSHAT00000000368

Organism

Sarcophilus harrisii

Functional Description

Protein Length

803

Protein Sequence
(FASTA)

QKIRQQVKCY LQLAGVMGKN ECMQGLEVIE STNLKYFTKE MTAEFYALKG MFLAQINKSE 60

EANKAFSAAV QMHDVLVKAW AMWGDYLENI FVKERQLHLG VSAITCYLHA CRHQNESKSR 120

KYLAKVLWLL SFDDDKNTLA DAVDKYCIGV PPIQWLAWIP QLLTCLVGSE GKLLLNLISQ 180

VGRVYPQAVY FPIRTLYLTL KIEQRERYKS DSGQQQPSSV GNQSHSASDP GPIRATAPMW 240

RCSRIMHMQR ELHPTLLSSL EGIVDQMVWF RENWHEEVLR QLQQGLAKCY SVAFEKSGAV 300

SDAKITPHTL NFVKKLVSTF GVGLENVSNV STMFSSAASE SLARRAQATA QDPVFQKLKG 360

QFTTEDFDFS VPGSMKLHNL ISKLKKWIKI LEAKTKQLPK FFLIEEKCRF LSNFSAQTAE 420

VEIPGEFLMP KPTHYYIKIA RFMPRVEIVQ KHNTAARRLY IRGHNGKIYP YLVMNDACLT 480

ESRREERVLQ LLRLLNPCLE KRKETTKRHL FFTVVPRVVA VSPQMRLVED NPSSLSLVEI 540

YKQRCAKKGI EHDNPISRYY DRLATVQARG TQASHQVLRD ILKEVQSNMV PRSMLREWAL 600

HTFPNATDYW TFRKMFTIQL ALIGFAEFVF HLNRLNPEML QIAQDTGKLN VAYFRFDIND 660

ATGDLDANRP VPFRLTPNIS EFLTTIGVSG PLTASMIAVA RCFAQPNFKV DGILKTVLRD 720

EIIAWHKKTQ EDTSSPLSAA GQPENMDSQQ LVSLVQKAVT AIMTRLHNLA QFEGGESKVN 780

TLVAAANSLD NLCRMDPAWH PWL 803

Nucleotide Sequence
(FASTA)

CAGAAAATTC GACAGCAAGT CAAATGCTAT CTCCAGTTGG CTGGAGTCAT GGGCAAAAAT 60

GAATGTATGC AGGGCCTTGA AGTCATTGAA TCCACAAACT TGAAGTATTT CACAAAGGAG 120

ATGACGGCTG AATTTTATGC TTTAAAGGGA ATGTTCTTGG CACAGATTAA CAAGTCTGAG 180

GAGGCAAACA AAGCTTTTTC AGCAGCTGTG CAAATGCATG ATGTGTTGGT GAAGGCCTGG 240

GCAATGTGGG GTGATTACCT GGAAAATATA TTTGTGAAGG AGCGGCAGCT TCACCTTGGT 300

GTATCTGCCA TCACTTGCTA TTTGCATGCA TGTCGACATC AGAATGAGAG CAAATCAAGA 360

AAATACTTAG CCAAGGTATT ATGGCTCTTG AGTTTTGATG ATGACAAAAA TACGCTGGCA 420

GATGCAGTAG ATAAATACTG TATTGGAGTG CCTCCCATAC AGTGGTTGGC TTGGATTCCA 480

CAGCTATTAA CTTGTTTAGT TGGTTCTGAA GGCAAGCTTC TTTTGAACCT CATAAGTCAG 540

GTTGGAAGAG TATATCCTCA AGCTGTCTAT TTTCCTATAA GGACTCTATA TTTGACATTG 600

AAAATTGAGC AGCGAGAACG TTACAAAAGT GATTCTGGAC AGCAGCAACC AAGTTCAGTA 660

GGCAATCAGT CCCATTCTGC ATCAGATCCT GGACCAATTC GAGCCACAGC CCCAATGTGG 720

CGCTGCAGCA GAATTATGCA CATGCAGAGG GAATTGCATC CAACTCTTCT GTCTTCTCTG 780

GAAGGCATTG TTGATCAGAT GGTCTGGTTC AGAGAAAATT GGCACGAAGA GGTTCTCAGA 840

CAGCTTCAGC AGGGCCTGGC AAAATGTTAT TCAGTAGCTT TTGAGAAAAG TGGAGCAGTT 900

TCAGATGCCA AAATCACACC GCACACTCTT AATTTTGTAA AGAAGTTGGT CAGCACCTTT 960

GGAGTTGGCT TGGAAAATGT GTCTAATGTC TCTACCATGT TTTCCAGTGC TGCCTCTGAG 1020

TCTTTGGCTA GACGAGCACA AGCAACAGCA CAGGATCCTG TTTTTCAGAA ATTGAAAGGA 1080

CAGTTCACAA CAGAAGATTT TGACTTCAGT GTTCCAGGAT CAATGAAGCT TCACAATCTA 1140

ATCTCCAAAT TGAAAAAATG GATCAAAATA CTGGAGGCTA AAACCAAGCA GCTTCCCAAG 1200

TTCTTTCTCA TAGAAGAAAA GTGTCGTTTT CTAAGTAATT TCTCTGCACA AACTGCTGAA 1260

GTAGAAATCC CTGGAGAGTT CTTAATGCCA AAGCCAACAC ATTATTATAT CAAAATTGCA 1320

AGATTTATGC CCCGGGTAGA GATAGTACAG AAGCACAACA CTGCTGCCAG AAGACTCTAT 1380

ATTCGTGGGC ATAATGGGAA GATTTACCCC TACCTGGTCA TGAATGACGC TTGTTTGACA 1440

GAGTCTCGAA GAGAAGAGCG GGTTTTACAA CTTCTTCGCC TTTTGAATCC CTGTTTAGAG 1500

AAGAGAAAAG AAACCACAAA AAGGCACTTG TTTTTCACAG TAGTTCCTCG AGTTGTGGCA 1560

GTCTCTCCAC AGATGCGTCT TGTTGAAGAC AATCCCTCTT CCCTTTCTCT TGTCGAGATA 1620

TACAAACAAC GTTGTGCCAA GAAGGGCATT GAGCATGATA ACCCTATTTC TCGTTATTAC 1680

GACAGATTGG CAACTGTGCA GGCACGGGGG ACTCAAGCCA GTCATCAGGT TCTTCGTGAT 1740

ATTCTCAAGG AAGTTCAAAG TAACATGGTG CCTAGAAGCA TGCTAAGAGA ATGGGCTTTG 1800

CACACATTTC CCAATGCCAC TGATTACTGG ACCTTTCGAA AGATGTTCAC AATCCAGCTA 1860

GCGCTAATTG GTTTTGCAGA ATTTGTATTT CATTTGAATA GACTCAATCC AGAGATGTTA 1920

CAGATTGCAC AGGACACTGG CAAACTTAAC GTTGCCTATT TTCGATTTGA TATTAATGAT 1980

GCTACTGGAG ATCTGGATGC TAATCGTCCT GTGCCATTCC GCCTCACACC TAATATTTCA 2040

GAATTCTTGA CCACAATTGG GGTCTCTGGT CCATTAACTG CTTCTATGAT TGCTGTGGCT 2100

CGGTGTTTTG CACAACCAAA CTTTAAGGTT GATGGCATTC TGAAAACAGT GCTTCGGGAT 2160

GAAATTATTG CTTGGCACAA GAAGACACAA GAGGACACCT CCTCTCCGCT CTCTGCAGCG 2220

GGGCAGCCTG AGAACATGGA TAGCCAGCAG CTGGTTTCCC TGGTGCAGAA AGCTGTGACT 2280

GCTATCATGA CTCGACTCCA TAATCTCGCT CAGTTTGAAG GAGGAGAGAG CAAAGTCAAC 2340

ACCCTTGTCG CAGCTGCAAA TAGTCTGGAT AATCTGTGCC GCATGGATCC CGCCTGGCAT 2400

CCCTGGCTGT AA 2412

Domain Profile

S: 1     iagfderveilask.qkpkklllrGsdgkeypyLv...kgkeDlrqdervlqlfslvNtl  56

         ia+f++rvei++++ +++++l++rG++gk+ypyLv   ++++++r++ervlql++l+N +

Q: 439   IARFMPRVEIVQKHnTAARRLYIRGHNGKIYPYLVmndACLTESRREERVLQLLRLLNPC  498

         89************99********************************************

S: 57    LakdketsrrkLkir.tykVvplstrsgliewventvsLkellkklvekkavlldqpisy  115

         L+k+ket++r+L+++ +++Vv++s++++l+e++++++sL+e++k++++kk++++d+pis+

Q: 499   LEKRKETTKRHLFFTvVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISR  558

         ************998469******************************************

S: 116   rykdlstvqarkpklkhlklslevfkevlenlvpkdllkklllekfpspeewfelrkayt  175

         +y++l+tvqar+++++h++l+ +++kev++n+vp+++l++++l++fp++++++++rk++t

Q: 559   YYDRLATVQARGTQASHQVLR-DILKEVQSNMVPRSMLREWALHTFPNATDYWTFRKMFT  617

         *********************.**************************************

S: 176   rslAvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTr  235

         ++lA+i++++++ +L+++++e+l+i+q+tg++++++f++++++a+ +l+++++vPFRLT+

Q: 618   IQLALIGFAEFVFHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTP  677

         ************************************************************

S: 236   nivnalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkkkkktsketee  295

         ni+++l+++gv+G+++as++av+r+++++++k+++iL+++l+d++++w+k  kt+++t++

Q: 678   NISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHK--KTQEDTSS  735

         *************************************************8..9*******

S: 296   elaekakaealkikkllskvekaenavatrd  326

         +l+++ ++e++++++l+s v+ka++a++tr

Q: 736   PLSAAGQPENMDSQQLVSLVQKAVTAIMTRL  766

         ****************************985

Domain Sequence
(FASTA)

IARFMPRVEI VQKHNTAARR LYIRGHNGKI YPYLVMNDAC LTESRREERV LQLLRLLNPC 60

LEKRKETTKR HLFFTVVPRV VAVSPQMRLV EDNPSSLSLV EIYKQRCAKK GIEHDNPISR 120

YYDRLATVQA RGTQASHQVL RDILKEVQSN MVPRSMLREW ALHTFPNATD YWTFRKMFTI 180

QLALIGFAEF VFHLNRLNPE MLQIAQDTGK LNVAYFRFDI NDATGDLDAN RPVPFRLTPN 240

ISEFLTTIGV SGPLTASMIA VARCFAQPNF KVDGILKTVL RDEIIAWHKK TQEDTSSPLS 300

AAGQPENMDS QQLVSLVQKA VTAIMTRL 328

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

; F:phosphotransferase activity, alcohol group as acceptor

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR011990	; TPR-like_helical.

Pfam

PF02259	; FAT; 1.
PF00454	; PI3_PI4_kinase; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013