EKS-SAH-00397

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00397

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	339.7	1.1E-101	68	342	275

Status

Unreviewed

Ensembl Protein

ENSSHAP00000001914

UniProt Accession

G3VFF8;

Protein Name

Protein Synonyms/Alias

Gene Name

WEE2

Gene Synonyms/Alias

WEE2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000001703	ENSSHAP00000001914	ENSSHAT00000001935
ENSSHAG00000001703	ENSSHAP00000001913	ENSSHAT00000001934
ENSSHAG00000001703	ENSSHAP00000001912	ENSSHAT00000001933

Organism

Sarcophilus harrisii

Functional Description

Protein Length

423

Protein Sequence
(FASTA)

MSSPVQVNVN PFTPESYRRM VSQSSGKRKI REEPQVSDFS EDNEEQGLPA KRYVTRESNM 60

ASRYEKEFLE LEKIGVGAFG SVYKCIKRLD GYIYAIKRST RRLGGSTNEL SALREVYAHA 120

VLGQHPHVVR YYSAWAEDDH MIIQNEYCNG GSLQAAVSEN EKLGRFFQEP ELKNMLLQIS 180

MGLKYIHHSG LVHLDIKPSN IFICKKQEDD IPYVSEEGEN EDDWFLSAKV MYKIGDLGLV 240

TSIQSPQVEE GDSRFLANEV LQEDYRFLPK ADVFALGLTI AVAAGAKSLP TNDEPWHRIR 300

RGNLPALPQK LSKDFYNLLK YMIHPKPEER PTAAALVRNT VIRPFLSITA KLQKELDREK 360

SKTAKLEREL KEVHLAQSHQ EDTSQRSLAL LGLLAKTGSS SSSRLVGGKV KRSHSFTFGK 420

CRP 423

Nucleotide Sequence
(FASTA)

ATGTCTTCAC CAGTTCAGGT TAATGTGAAC CCATTCACCC CAGAATCCTA CAGGAGGATG 60

GTCTCCCAAT CCAGTGGCAA GAGGAAAATA AGGGAAGAGC CTCAGGTATC TGACTTCTCT 120

GAAGACAATG AAGAGCAAGG GCTTCCTGCC AAGAGATATG TCACAAGAGA AAGCAACATG 180

GCTTCCCGAT ATGAAAAGGA ATTCCTGGAG TTAGAAAAAA TTGGGGTAGG AGCATTTGGT 240

TCTGTCTACA AGTGCATCAA GAGGCTGGAT GGATATATTT ATGCTATTAA ACGCTCAACA 300

AGACGTTTGG GAGGATCCAC AAATGAACTC TCAGCTTTGC GAGAAGTTTA CGCACATGCA 360

GTGCTGGGAC AGCATCCCCA CGTTGTCCGT TACTATTCTG CATGGGCAGA GGATGACCAT 420

ATGATCATTC AGAATGAGTA CTGTAATGGT GGGAGCTTGC AGGCTGCTGT GTCTGAAAAT 480

GAGAAACTTG GCCGTTTCTT CCAAGAGCCA GAACTCAAGA ATATGCTCCT GCAAATCTCC 540

ATGGGGCTAA AATATATCCA CCACTCAGGC CTGGTGCATC TGGACATCAA GCCCAGTAAC 600

ATTTTCATCT GTAAAAAACA AGAAGATGAT ATCCCATATG TCTCAGAAGA AGGAGAGAAT 660

GAAGATGACT GGTTCCTTTC TGCTAAAGTG ATGTATAAAA TTGGTGATTT GGGCCTTGTT 720

ACTTCAATCC AGAGCCCCCA AGTAGAGGAG GGAGATAGTC GCTTCTTGGC CAATGAGGTT 780

TTACAAGAGG ACTATCGATT CCTGCCCAAA GCAGATGTGT TTGCCCTTGG ATTGACAATT 840

GCTGTAGCTG CAGGGGCAAA GTCATTACCA ACCAATGATG AGCCTTGGCA CCGTATCCGT 900

AGAGGCAACC TTCCAGCTCT CCCACAGAAG CTCTCTAAAG ACTTTTACAA TTTGCTTAAG 960

TATATGATCC ATCCTAAGCC AGAAGAGAGG CCGACAGCAG CAGCTTTGGT TAGGAACACA 1020

GTCATCAGAC CGTTTTTGAG TATAACTGCA AAGCTTCAGA AGGAGCTGGA CAGAGAAAAA 1080

TCTAAGACGG CCAAGTTAGA GAGGGAACTG AAAGAAGTTC ATCTTGCCCA GAGCCACCAA 1140

GAAGATACCA GTCAACGTTC TCTTGCACTT CTTGGACTCC TCGCCAAAAC TGGGTCAAGT 1200

AGCTCCAGTA GATTGGTGGG AGGGAAAGTC AAAAGATCAC ACAGTTTCAC TTTTGGAAAA 1260

TGTAGGCCCT AG 1272

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F e+ekiG+G fg+v+k++kr+dg +yAik+s + l g+++e +alrEv+ahavlgqh++

Q: 68    FLELEKIGVGAFGSVYKCIKRLDGYIYAIKRSTRRLGGSTNELSALREVYAHAVLGQHPH  127

         7899********************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         vvry+saW+edd+++iq+E+C+ggsL+aa++e+e+  + ++e elk++ll+++ gl+y+H

Q: 128   VVRYYSAWAEDDHMIIQNEYCNGGSLQAAVSENEKLGRFFQEPELKNMLLQISMGLKYIH  187

         ************************************************************

S: 121   ssslvHlDikpenifi.......................tkevtlklgDlGlvtelnsed  157

          s lvHlDikp+nifi                       +++v++k+gDlGlvt++   +

Q: 188   HSGLVHLDIKPSNIFIckkqeddipyvseegeneddwflSAKVMYKIGDLGLVTSI---Q  244

         ********************************************************...9

S: 158   kskveEGDsrylakEilqeeyskl.kaDiFslgltilevaanvelPsnGeaWhklRkgkl  216

         +++veEGDsr+la+E+lqe+y+ l kaD+F+lglti+++a++ +lP+n e Wh++R+g+l

Q: 245   SPQVEEGDSRFLANEVLQEDYRFLpKADVFALGLTIAVAAGAKSLPTNDEPWHRIRRGNL  304

         ************************************************************

S: 217   pdeilkelsedlrellklmlepdperRptaeellkhevl  255

         p  + ++ls+d+ +llk m++p+pe+Rpta++l++++v+

Q: 305   P-ALPQKLSKDFYNLLKYMIHPKPEERPTAAALVRNTVI  342

         *.********************************99875

Domain Sequence
(FASTA)

FLELEKIGVG AFGSVYKCIK RLDGYIYAIK RSTRRLGGST NELSALREVY AHAVLGQHPH 60

VVRYYSAWAE DDHMIIQNEY CNGGSLQAAV SENEKLGRFF QEPELKNMLL QISMGLKYIH 120

HSGLVHLDIK PSNIFICKKQ EDDIPYVSEE GENEDDWFLS AKVMYKIGDL GLVTSIQSPQ 180

VEEGDSRFLA NEVLQEDYRF LPKADVFALG LTIAVAAGAK SLPTNDEPWH RIRRGNLPAL 240

PQKLSKDFYN LLKYMIHPKP EERPTAAALV RNTVI 275

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004715	; F:non-membrane spanning protein tyrosine kinase activity
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007067	; P:mitosis

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR017164	; Wee1-like_protein_kinase.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013