EKS-SAH-00188

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00188

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/LISK	268.7	5.4E-80	367	576	210

Status

Unreviewed

Ensembl Protein

ENSSHAP00000002411

UniProt Accession

G3VGV7;

Protein Name

Protein Synonyms/Alias

Gene Name

LIMK1

Gene Synonyms/Alias

LIMK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000002136	ENSSHAP00000002411	ENSSHAT00000002437

Organism

Sarcophilus harrisii

Functional Description

Protein Length

576

Protein Sequence
(FASTA)

MDGLGRENGR TPPCHLSVLK LNHKPQGQDG GWFCLPRGSD LPVCSSCGQS IFDGQYLQAL 60

NADWHSDCFR PRCCECGASL SHQYYEKDGQ LYCKKDYWVR YGESCHGCSE QITKGLVMVA 120

GDQKYHPECF ICLTCGAFIG DGDTYALVER SKLYCGHCYY QMVVTPVIEQ ILPDSPGSRL 180

PHTVTLVSIP ASADGKRGLS VSIDPPYGQH GSGSEHSHTV RVRGVDPDCI SPDVKNSIHI 240

GDRILEINGT PIRNVPLDEI DLLIQETSRL LQLTIEHDPH DVLAHGTVPE ASPLADLQSP 300

LCSPAQTPTT EAGGPVRQRP VLRSCSIDKS PCGSSLGSPA SQRKDLGRSE SLRIVSRTHR 360

IFRPSDLIHG EVLGKGCFGQ AIKVTHRETG EVMVMKELIR FDEETQRTFL KESMGITERR 420

PLTLEPKAER ISTAILFISL GKNLLMGGLE GGAWGSQQES QKDSQYPWSQ RVSFAKDIAS 480

GMAYLHSMNI IHRDLNSHNC LVRENKTVVV ADFGLARLMV DEKSQPDQLQ SLKKPDRKKR 540

YTVVGNPYWM APEMINGHSY DEKVDVFSFG IVLCEV 576

Nucleotide Sequence
(FASTA)

ATGGATGGGC TGGGACGGGA GAATGGAAGA ACCCCCCCTT GTCATCTTTC TGTTCTCAAG 60

TTGAACCATA AGCCTCAAGG GCAGGATGGG GGCTGGTTTT GTCTGCCACG AGGAAGTGAC 120

CTGCCCGTGT GTTCAAGCTG TGGCCAGAGC ATCTTTGACG GGCAGTACCT CCAGGCCCTG 180

AATGCGGACT GGCATTCCGA CTGCTTCAGG CCCAGGTGCT GTGAGTGCGG CGCCTCCCTC 240

TCCCACCAGT ACTATGAGAA GGATGGGCAG CTGTACTGCA AGAAGGACTA CTGGGTCCGC 300

TACGGTGAAT CCTGCCATGG CTGCTCCGAG CAGATCACCA AAGGGCTGGT CATGGTGGCA 360

GGGGACCAGA AGTACCATCC TGAATGCTTC ATCTGCCTCA CATGTGGGGC ATTCATTGGG 420

GACGGGGACA CCTATGCTCT GGTGGAACGA TCCAAGCTCT ACTGCGGACA TTGCTATTAC 480

CAAATGGTAG TGACTCCGGT CATCGAGCAG ATCCTGCCTG ACTCACCGGG GTCCCGCCTC 540

CCGCATACGG TCACCTTGGT GTCCATCCCA GCTTCTGCTG ATGGCAAACG GGGGCTCTCT 600

GTGTCTATCG ACCCACCCTA TGGCCAGCAT GGCAGCGGCT CTGAGCACTC CCATACTGTT 660

CGCGTTCGGG GAGTGGACCC AGATTGTATC AGCCCAGACG TGAAGAACTC CATCCACATT 720

GGAGATAGAA TCCTAGAAAT CAATGGTACT CCCATCCGGA ACGTCCCTTT GGATGAGATC 780

GACCTGCTGA TCCAGGAGAC CAGCCGCCTT CTCCAGTTGA CCATTGAGCA TGACCCCCAT 840

GACGTCCTGG CTCATGGCAC AGTGCCGGAG GCCAGCCCTC TGGCAGATCT GCAAAGCCCA 900

CTGTGTTCCC CAGCCCAAAC ACCCACCACA GAAGCAGGGG GGCCCGTCCG GCAGAGACCT 960

GTCCTGAGAA GCTGCAGCAT TGACAAGTCA CCCTGTGGCA GCTCCCTGGG TTCCCCAGCC 1020

TCCCAGCGGA AGGACCTGGG CCGTTCTGAG TCCCTCCGAA TTGTCTCCCG CACCCACCGC 1080

ATCTTCCGGC CCTCTGACCT CATTCACGGG GAAGTGCTGG GGAAGGGCTG CTTCGGACAA 1140

GCCATCAAGG TGACTCACCG GGAGACCGGC GAGGTGATGG TGATGAAGGA GCTCATCCGA 1200

TTTGACGAGG AGACGCAGAG GACGTTTCTC AAAGAGTCAA TGGGAATCAC AGAGAGGCGA 1260

CCTCTGACCT TAGAGCCAAA GGCGGAAAGA ATCAGCACCG CCATATTATT CATTAGTTTG 1320

GGAAAAAACC TACTGATGGG GGGGCTGGAA GGCGGGGCAT GGGGGTCCCA GCAGGAGAGC 1380

CAGAAGGACA GCCAGTACCC ATGGAGCCAG CGGGTCAGCT TTGCCAAGGA CATCGCCTCG 1440

GGAATGGCCT ATCTGCACTC CATGAACATC ATCCACAGAG ACCTGAATTC CCACAACTGC 1500

TTGGTGCGAG AGAACAAAAC CGTCGTCGTG GCCGACTTTG GGCTGGCGCG GCTCATGGTG 1560

GACGAGAAGA GCCAGCCCGA CCAGCTGCAG AGCCTGAAGA AGCCCGACCG GAAGAAGCGG 1620

TACACCGTGG TGGGGAACCC CTACTGGATG GCACCTGAGA TGATCAATGG GCACAGCTAT 1680

GACGAGAAGG TGGATGTCTT TTCCTTTGGC ATTGTCCTCT GTGAGGTA 1728

Domain Profile

S: 1     livgeklGkGffsevfkvthrasGevmvlkeliradeenrknllkevkllrk...le.hp  56

         li+ge+lGkG+f++++kvthr++Gevmv+kelir+dee+++++lke   + +   l   p

Q: 367   LIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKESMGITErrpLTlEP  426

         689*******************************************65543212233233

S: 57    nvlkf.iGvlvkdkklhllteyiegGtlkellkskes..lpwtqrvrlakdiasGlsylh  113

         +  +    +l+     +ll   +egG+     +s++   +pw+qrv++akdiasG++ylh

Q: 427   KAERIsTAILFISLGKNLLMGGLEGGAWGSQQESQKDsqYPWSQRVSFAKDIASGMAYLH  486

         33343145777777789999******9866555543335*********************

S: 114   skgiihrdlnsknclvredksvvvadfGlarlvveerkkseklrslkkkdrkkrltvvGs  173

         s++iihrdlns+nclvre+k+vvvadfGlarl+v+e+ ++++l+slkk drkkr+tvvG+

Q: 487   SMNIIHRDLNSHNCLVRENKTVVVADFGLARLMVDEKSQPDQLQSLKKPDRKKRYTVVGN  546

         ************************************************************

S: 174   PywmaPevlkgksydekvdvfsfGivlcei  203

         PywmaPe+++g+sydekvdvfsfGivlce+

Q: 547   PYWMAPEMINGHSYDEKVDVFSFGIVLCEV  576

         ****************************97

Domain Sequence
(FASTA)

LIHGEVLGKG CFGQAIKVTH RETGEVMVMK ELIRFDEETQ RTFLKESMGI TERRPLTLEP 60

KAERISTAIL FISLGKNLLM GGLEGGAWGS QQESQKDSQY PWSQRVSFAK DIASGMAYLH 120

SMNIIHRDLN SHNCLVRENK TVVVADFGLA RLMVDEKSQP DQLQSLKKPD RKKRYTVVGN 180

PYWMAPEMIN GHSYDEKVDV FSFGIVLCEV 210

Keyword

ATP-binding; Complete proteome; LIM domain; Metal-binding; Nucleotide-binding; Reference proteome; Zinc.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>