EPS-SAH-00024

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-SAH-00024

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	191.6	2.2E-56	88	341	254

Status

Unreviewed

Ensembl Protein

ENSSHAP00000003208

UniProt Accession

G3VJ53;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1E

Gene Synonyms/Alias

PPM1E;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000002831	ENSSHAP00000003208	ENSSHAT00000003244

Organism

Sarcophilus harrisii

Functional Description

Protein Length

610

Protein Sequence
(FASTA)

EVCLPFIFFS NCPSFLAAAL ARATSDEVLQ SDLSMYYIPK ETDGSEGTVE IETVKLARSV 60

FSKLHEICCS WVKDFPLRRK PQLYYETSIH AIKNMRRKME DKHVCIPDFN MLFNLEDQEE 120

QAYFAVFDGH GGVDAAIYAS VHLHVNLVRQ EMFPHDPAEA LCRAFRVTDE RFVQKAARES 180

LRCGTTGVVT FIRGNMLHVA WLGDSQVMLV RKGQAVELMK PHKPDREDEK QRIEALGGCV 240

VWFGAWRVNG SLSVSRAIGD AEHKPYICGD ADSASTVLDG SEDYLILACD GFYDTVNPDE 300

AVKVVADHLK ENNGDSSMVA HKLVASARDA GSSDNITVIV VFLRDMNKAI NVREESDWTE 360

NSFQGGQEDG GDDKENHGES KRPWPQHQCS APADLGYDGR VDSFTDRTSL STGSQINVLE 420

DAGYLDLTQI EASKPQSAKF WSPVEMFGLT VPKKANLVND IIMEKESVRS SVHEQHNAGE 480

YPAYLNLGST YRMESLSPVF SRLENEQENK PPGKRASSFS HLRHYYAKRR HGFRLKPKFH 540

TFLFAHEPSH KAGTTSLSSL IRSGNRNRRL VRSSLTWRQN AYKKYSEILM GMLRNSNCIP 600

YADIPWSSKI 610

Nucleotide Sequence
(FASTA)

GAAGTCTGCC TTCCCTTTAT CTTTTTCAGT AATTGCCCTT CCTTTTTGGC TGCTGCTTTA 60

GCCAGAGCAA CATCAGATGA AGTCCTTCAG AGTGATCTTT CTATGTACTA TATACCAAAG 120

GAAACAGATG GCTCAGAGGG GACTGTGGAG ATTGAGACAG TGAAATTGGC ACGTTCTGTC 180

TTCAGCAAAC TACATGAGAT TTGCTGCAGT TGGGTGAAGG ACTTCCCTCT CCGCAGGAAA 240

CCCCAATTGT ATTATGAGAC ATCAATCCAT GCCATCAAAA ACATGCGCAG GAAAATGGAG 300

GACAAACACG TCTGCATTCC TGATTTTAAT ATGCTCTTCA ATCTAGAGGA TCAAGAAGAA 360

CAAGCTTACT TTGCTGTGTT TGATGGGCAC GGTGGAGTGG ATGCTGCTAT TTACGCTTCT 420

GTCCACCTCC ATGTGAACTT GGTGCGCCAG GAAATGTTCC CCCATGATCC TGCAGAGGCT 480

CTGTGCCGGG CCTTCCGCGT GACCGACGAG CGTTTTGTGC AGAAAGCAGC CAGGGAGAGC 540

TTACGCTGTG GGACCACAGG TGTGGTGACA TTTATCCGAG GCAACATGCT CCACGTAGCC 600

TGGCTGGGCG ACTCTCAGGT GATGCTTGTG AGGAAGGGCC AAGCTGTAGA ATTAATGAAG 660

CCACATAAAC CGGATCGGGA GGATGAGAAG CAACGAATTG AGGCCCTTGG AGGCTGTGTG 720

GTCTGGTTTG GTGCCTGGAG AGTGAATGGA AGTCTGTCTG TCTCAAGAGC TATTGGAGAT 780

GCTGAGCATA AGCCATATAT CTGTGGGGAT GCAGACTCTG CCTCCACTGT TTTAGATGGG 840

TCTGAAGACT ACCTCATTTT AGCTTGCGAC GGCTTCTATG ATACCGTAAA CCCCGATGAG 900

GCAGTGAAGG TCGTGGCTGA CCACCTGAAG GAAAATAATG GAGACAGTAG CATGGTTGCC 960

CACAAATTGG TAGCATCAGC TCGTGATGCT GGGTCAAGTG ACAATATCAC TGTCATTGTG 1020

GTGTTCCTGA GGGATATGAA CAAAGCTATA AATGTTAGGG AGGAATCAGA CTGGACAGAG 1080

AACTCTTTTC AAGGAGGTCA AGAAGATGGC GGGGATGATA AGGAAAATCA TGGAGAAAGC 1140

AAACGCCCCT GGCCTCAGCA CCAGTGCTCG GCACCCGCAG ATCTAGGCTA TGATGGGCGA 1200

GTGGATTCAT TCACTGATAG AACTAGCTTG AGCACAGGGT CCCAAATCAA TGTGCTTGAA 1260

GATGCAGGCT ACCTAGATCT CACACAAATA GAAGCAAGCA AACCTCAGAG TGCCAAATTT 1320

TGGTCACCCG TTGAAATGTT TGGTCTTACA GTACCAAAGA AAGCAAATCT TGTTAATGAT 1380

ATAATAATGG AGAAAGAATC AGTCCGGTCT TCAGTGCATG AACAGCATAA TGCTGGAGAA 1440

TACCCTGCTT ATCTTAATTT GGGTTCAACA TACAGAATGG AGAGTTTGTC TCCAGTCTTT 1500

TCTAGGTTGG AAAATGAACA GGAAAATAAA CCCCCGGGAA AGAGAGCTTC TAGTTTCTCT 1560

CATTTACGCC ACTATTATGC AAAGAGACGG CATGGATTCA GGCTCAAACC AAAGTTTCAT 1620

ACGTTTCTCT TTGCTCACGA GCCTTCCCAC AAAGCAGGCA CAACTAGCCT GTCTTCACTT 1680

ATTCGAAGTG GGAATAGAAA TAGGAGGTTG GTAAGAAGTT CTCTGACATG GAGACAAAAT 1740

GCTTACAAAA AGTACAGTGA GATTCTAATG GGGATGCTTA GAAACAGTAA TTGTATACCA 1800

TATGCAGACA TTCCCTGGAG CAGTAAAATA TAA 1833

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdr..laffgvyDGhggsevakfcseklheil  61

         ++ +++++r++med++   p+f    + +d+   a+f+v+DGhgg ++a ++s +lh  l

Q: 88    SIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQeeQAYFAVFDGHGGVDAAIYASVHLHVNL  147

         567899**************99766555544459************************99

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvan  121

          ++         +  +al +aF  tde++  ++++  ++ ++G+t vv  i+++ l+va

Q: 148   VRQEM----FPHDPAEALCRAFRVTDERF--VQKAARESLRCGTTGVVTFIRGNMLHVAW  201

         99955....6788888999**********..7777788888*******************

S: 122   vGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdga.RvlGvLavsRalGd  180

         +GdS+++L r+g+avel + Hkp+redE++Rie+ gg v+ + ga Rv+G+L vsRa+Gd

Q: 202   LGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVV-WFGAwRVNGSLSVSRAIGD  260

         *************************************999.55899**************

S: 181   lylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle.kkeaeqeaa  239

          + kpy+  + +  s+ l+ ++++liLa+DG +d+v++ eav++v d+l+ ++ + + +a

Q: 261   AEHKPYICGDADSASTVLDGSEDYLILACDGFYDTVNPDEAVKVVADHLKeNNGDSSMVA  320

         ************************************************9966778899**

S: 240   kkLvklalargskdnvsaivv  260

         +kLv+ a++ gs+dn+++ivv

Q: 321   HKLVASARDAGSSDNITVIVV  341

         *****************9997

Domain Sequence
(FASTA)

SIHAIKNMRR KMEDKHVCIP DFNMLFNLED QEEQAYFAVF DGHGGVDAAI YASVHLHVNL 60

VRQEMFPHDP AEALCRAFRV TDERFVQKAA RESLRCGTTG VVTFIRGNML HVAWLGDSQV 120

MLVRKGQAVE LMKPHKPDRE DEKQRIEALG GCVVWFGAWR VNGSLSVSRA IGDAEHKPYI 180

CGDADSASTV LDGSEDYLIL ACDGFYDTVN PDEAVKVVAD HLKENNGDSS MVAHKLVASA 240

RDAGSSDNIT VIVV 254

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>