EKS-SAH-00395

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00395

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	530.9	6.8E-160	33	290	258

Status

Unreviewed

Ensembl Protein

ENSSHAP00000003871

UniProt Accession

G3VL17;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK2

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000003409	ENSSHAP00000003872	ENSSHAT00000003911
ENSSHAG00000003409	ENSSHAP00000003871	ENSSHAT00000003910

Organism

Sarcophilus harrisii

Functional Description

Protein Length

362

Protein Sequence
(FASTA)

MDPSASTSLQ TSTPNGNINL GPSANPNARP TDFDFLKVIG KGSYGKVLLA KHKSDGKFYA 60

VKVLQKKSIL KKKEQNHIMA ERNVLLKNVT HPFLVGLRYS FQTSEKLYFV LDYVNGGELF 120

FHLQREHCFL EPRARFYAAE VASAIGYLHS LNIIYRDLKP ENILLDCQGH VVLTDFGLCK 180

EGMEPEETTS TFCGTPEYLA PEVLRKQPYD RTVDWWCLGA VLYEMLCGLP PFYSRDVSEM 240

YENILHKPLQ IQGGKTVAAC DVLHGLLQKD QKKRLGAKED FLEIKNHVFF SPINWDDLYH 300

KRLTPPFNPN VVGPADLRHF DPEFTKETIS SSIGRTPDLT ASSSGASSAF LGFSYAPGDE 360

NF 362

Nucleotide Sequence
(FASTA)

ATGGATCCTT CTGCAAGTAC TAGCCTCCAG ACCTCAACAC CCAATGGAAA TATCAATTTA 60

GGACCATCAG CAAATCCAAA TGCCAGGCCA ACAGACTTTG ACTTCCTGAA AGTCATTGGA 120

AAAGGGAGCT ATGGAAAAGT TCTCTTGGCC AAACACAAAT CTGATGGGAA ATTTTATGCT 180

GTAAAAGTCT TACAGAAGAA ATCTATCTTG AAAAAGAAAG AGCAAAATCA CATCATGGCA 240

GAGCGCAATG TACTCCTAAA GAATGTGACA CATCCTTTCC TGGTGGGTCT CCGCTATTCC 300

TTTCAAACTT CAGAGAAGCT CTATTTTGTC TTAGACTACG TCAATGGAGG AGAGCTCTTC 360

TTCCACTTGC AGCGGGAGCA CTGCTTCCTA GAACCTCGGG CTCGATTCTA TGCTGCTGAG 420

GTGGCCAGTG CTATTGGCTA CCTGCATTCT CTGAACATCA TTTACAGGGA TTTGAAACCT 480

GAGAACATAC TCTTGGATTG CCAGGGACAT GTTGTGTTGA CTGATTTTGG ACTTTGTAAA 540

GAAGGAATGG AACCAGAAGA AACCACATCC ACTTTCTGTG GCACTCCTGA GTATTTGGCT 600

CCTGAAGTAT TGAGAAAACA ACCTTATGAC CGAACAGTAG ACTGGTGGTG TTTGGGGGCT 660

GTTCTTTATG AGATGCTCTG TGGCTTGCCA CCTTTTTATA GTCGAGATGT TTCTGAAATG 720

TATGAGAACA TCCTTCACAA GCCTCTCCAG ATCCAGGGAG GCAAGACAGT GGCAGCCTGT 780

GACGTTCTTC ATGGTCTTCT CCAAAAAGAC CAGAAGAAAA GACTGGGTGC CAAAGAAGAC 840

TTTCTTGAGA TAAAGAATCA TGTCTTCTTC AGCCCAATAA ACTGGGATGA CTTATACCAC 900

AAGAGACTTA CTCCTCCTTT CAACCCAAAT GTGGTGGGGC CAGCTGATTT AAGACACTTC 960

GACCCAGAAT TCACTAAGGA AACAATTTCC AGTTCTATTG GACGCACACC GGATTTAACA 1020

GCCAGCAGCT CTGGGGCTTC CAGTGCATTC TTAGGATTTT CTTATGCACC TGGGGATGAG 1080

AATTTTTAA 1089

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgs+gkvllak+k+d+kfyavkvlqkk+ilkkke++himaernvllknv hp

Q: 33    FDFLKVIGKGSYGKVLLAKHKSDGKFYAVKVLQKKSILKKKEQNHIMAERNVLLKNVTHP  92

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvgl+ysfqt+eklyfvldyvnggelffhlqre++fleprarfyaae+asa+gylhsln

Q: 93    FLVGLRYSFQTSEKLYFVLDYVNGGELFFHLQREHCFLEPRARFYAAEVASAIGYLHSLN  152

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         i+yrdlkpenilld++ghvvltdfglcke++e e+ttstfcgtpeylapevlrk+pydrt

Q: 153   IIYRDLKPENILLDCQGHVVLTDFGLCKEGMEPEETTSTFCGTPEYLAPEVLRKQPYDRT  212

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyeml glppfysrdv+emy+nil+kplq+++g +vaa+++l++ll+kd+k

Q: 213   VDWWCLGAVLYEMLCGLPPFYSRDVSEMYENILHKPLQIQGGKTVAACDVLHGLLQKDQK  272

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         krlgakedfleiknhvff

Q: 273   KRLGAKEDFLEIKNHVFF  290

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SYGKVLLAKH KSDGKFYAVK VLQKKSILKK KEQNHIMAER NVLLKNVTHP 60

FLVGLRYSFQ TSEKLYFVLD YVNGGELFFH LQREHCFLEP RARFYAAEVA SAIGYLHSLN 120

IIYRDLKPEN ILLDCQGHVV LTDFGLCKEG MEPEETTSTF CGTPEYLAPE VLRKQPYDRT 180

VDWWCLGAVL YEMLCGLPPF YSRDVSEMYE NILHKPLQIQ GGKTVAACDV LHGLLQKDQK 240

KRLGAKEDFL EIKNHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013