EKS-SAH-00302

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00302

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	320.6	8.3E-96	28	281	254

Status

Unreviewed

Ensembl Protein

ENSSHAP00000006179

UniProt Accession

G3VSM4;

Protein Name

Protein Synonyms/Alias

Gene Name

TAOK1

Gene Synonyms/Alias

TAOK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000005376	ENSSHAP00000006179	ENSSHAT00000006233

Organism

Sarcophilus harrisii

Functional Description

Protein Length

1005

Protein Sequence
(FASTA)

MPSTSRAGSL KDPEIAELFF KEDPEKLFTD LREIGHGSFG AVYFARDVRT NEVVAIKKMS 60

YSGKQSNEKW QDIIKEVKFL QRIKHPNSIE YKGCYLREHT AWLVMEYCLG SASDLLEVHK 120

KPLQEVEIAA ITHGALQGLA YLHSHNMIHR DIKAGNILLT EPGQVKLADF GSASIASPAN 180

SFVGTPYWMA PEVILAMDEG QYDGKVDVWS LGITCIELAE RKPPLFNMNA MSALYHIAQN 240

ESPTLQSNEW SDYFRNFVDS CLQKIPQDRP TSDELLKHMF VLRERPETVL IDLIQRTKDA 300

VRELDNLQYR KMKKLLFQEA HNGPAVEAQE EEEEQEHVVG RTGTVNSVGS NQSIPSMSIS 360

ASSQSSSVNS LPDASDDKSE LDMMEGDHTV MSNSSVIHLK PTKESYDSAI TPESEIIGPI 420

TLCGVEKTET HLRNRGHYSS CCPLNACVFN VTRQMQEHEQ DSELREQMSG YKRMRRQHQK 480

QLMALENKLK AEMDEHRLRL DKDLETQRNN FAAEMEKLIK KHQAAMEKEA KVMANEEKKF 540

QQHIQAQQKK ELNSFLESQK REYKLRKEQL KEELNENQST PKKEKQEWLS KQKENIQHFQ 600

AEEEANLLRR QRQYLELECR RFKRRMLLSR HNLEQDLVRE ELNKRQTQKD LEHAMLLRQH 660

ESMQELEFRH LSTIQKMRCE LIRLQHQTEL TNQLEYNKRR ERELRRKHVM EVRQQPKSLK 720

SKELQIKKQF QDTCKIQTRQ YKALRNHLLE TTPKSEHKAV LKRLKEEQTR KLAILAEQYD 780

HSINEMLSTQ ALRLDEAQEA ECQVLKMQLQ QELELLNAYQ SKIKMQAEAQ HDRELRELEQ 840

RVSLRRALLE QKIEEEMLAL QNERTERIRS LLERQAREIE AFDSESMRLG FSNMVLSNLS 900

PEAFSHSYPG ASGWSHNPTG GPGPHWGHPM GGPPQAWGHP MQGGPQPWGH PSGPMQGVPR 960

GSGMGVRNSP QALRRPASGG RTEQGMSRST SVTSQISNGS HMSYT 1005

Nucleotide Sequence
(FASTA)

ATGCCATCAA CTAGCCGAGC GGGCAGCCTG AAGGACCCAG AAATCGCAGA GCTCTTCTTC 60

AAAGAAGATC CAGAGAAACT CTTCACAGAT CTAAGAGAGA TAGGACATGG GAGCTTTGGA 120

GCAGTATATT TTGCACGGGA TGTGCGCACT AATGAAGTGG TGGCCATCAA GAAAATGTCT 180

TATAGTGGAA AGCAGTCCAA TGAGAAATGG CAGGACATTA TTAAGGAAGT CAAGTTTCTA 240

CAGAGAATAA AGCATCCTAA CAGCATAGAG TACAAAGGCT GCTATTTGCG CGAGCACACT 300

GCATGGCTTG TAATGGAATA TTGTTTAGGA TCAGCCTCAG ACTTACTAGA AGTTCACAAA 360

AAGCCATTAC AAGAAGTGGA AATAGCAGCA ATTACACATG GTGCTCTCCA GGGATTGGCC 420

TACTTACATT CTCACAACAT GATCCATAGA GATATCAAAG CAGGAAATAT CCTCCTGACA 480

GAGCCAGGCC AGGTGAAACT TGCTGACTTT GGATCTGCTT CCATAGCATC TCCTGCCAAT 540

TCCTTTGTGG GGACGCCATA TTGGATGGCC CCAGAAGTAA TTTTAGCCAT GGATGAAGGG 600

CAATATGATG GCAAAGTAGA TGTTTGGTCT CTTGGAATAA CATGTATTGA GTTAGCGGAA 660

AGGAAGCCTC CTTTATTTAA TATGAACGCA ATGAGTGCCT TATATCATAT AGCTCAGAAT 720

GAATCCCCTA CATTACAATC CAATGAATGG TCTGATTATT TTCGAAACTT CGTAGATTCT 780

TGTCTTCAAA AAATTCCTCA AGATCGGCCT ACATCAGATG AACTTCTCAA GCACATGTTT 840

GTTCTTCGTG AGCGCCCTGA AACAGTGTTA ATAGACCTCA TTCAGAGAAC CAAGGATGCC 900

GTAAGAGAGC TGGACAACTT GCAATATCGG AAAATGAAGA AACTCCTTTT CCAGGAGGCA 960

CATAATGGGC CTGCTGTAGA AGCACAGGAG GAAGAAGAGG AGCAAGAGCA TGTTGTTGGC 1020

CGAACAGGAA CAGTGAATAG TGTTGGAAGT AATCAGTCCA TTCCCAGTAT GTCTATCAGT 1080

GCCAGTAGCC AAAGCAGTAG TGTTAACAGT CTTCCAGATG CCTCAGATGA CAAAAGTGAA 1140

TTAGATATGA TGGAGGGGGA TCATACAGTG ATGTCTAATA GCTCTGTCAT CCATTTAAAA 1200

CCTACTAAGG AAAGTTATGA TTCAGCCATA ACTCCTGAAT CTGAGATTAT TGGTCCTATT 1260

ACTTTATGTG GGGTAGAAAA GACTGAAACA CATTTAAGAA ATAGGGGACA TTACAGTTCG 1320

TGCTGTCCCT TAAATGCTTG TGTCTTTAAT GTTACTAGGC AGATGCAGGA ACATGAGCAA 1380

GACTCGGAGT TGAGAGAACA GATGTCTGGC TACAAGCGCA TGAGGCGGCA GCACCAGAAG 1440

CAGCTGATGG CTCTGGAGAA CAAGCTCAAG GCTGAGATGG ATGAGCACCG CCTCCGACTG 1500

GACAAAGACC TCGAGACACA GCGCAACAAT TTTGCCGCAG AAATGGAGAA ACTTATCAAG 1560

AAACACCAAG CAGCTATGGA GAAGGAGGCT AAGGTGATGG CCAACGAAGA GAAGAAATTC 1620

CAACAACATA TTCAAGCACA GCAGAAAAAA GAATTAAATA GCTTTTTAGA GTCCCAGAAG 1680

AGAGAATACA AACTACGCAA AGAGCAACTT AAGGAGGAGC TAAATGAAAA CCAGAGTACC 1740

CCAAAGAAAG AAAAACAAGA ATGGCTCTCC AAACAGAAGG AGAACATCCA GCACTTCCAA 1800

GCAGAAGAGG AGGCCAACCT CCTCAGAAGG CAAAGGCAGT ACCTGGAGCT GGAGTGCCGG 1860

CGCTTCAAAA GGAGAATGCT GCTCAGCCGT CACAATTTGG AACAGGATCT TGTCAGAGAG 1920

GAGTTAAATA AAAGGCAGAC CCAGAAGGAC TTGGAGCACG CCATGCTCCT GCGACAGCAC 1980

GAGTCCATGC AAGAGCTTGA GTTCCGCCAC CTCAGTACCA TTCAGAAGAT GCGCTGTGAA 2040

CTGATCAGGC TGCAGCACCA GACCGAGCTC ACCAACCAGC TGGAATACAA CAAGCGGCGG 2100

GAGCGGGAGC TGAGGCGCAA GCATGTCATG GAGGTTCGGC AACAGCCCAA GAGTCTGAAG 2160

TCTAAAGAAC TGCAAATAAA AAAACAATTT CAAGATACCT GCAAGATCCA GACCAGACAG 2220

TACAAAGCCT TGAGGAACCA CCTGTTGGAG ACCACACCAA AGAGTGAGCA CAAAGCAGTT 2280

CTCAAGCGGC TCAAGGAGGA GCAGACGAGG AAACTGGCCA TTCTGGCAGA GCAGTATGAT 2340

CACAGCATTA ACGAAATGCT CTCTACACAA GCTCTTCGTT TGGATGAGGC TCAGGAAGCT 2400

GAGTGCCAAG TCTTAAAGAT GCAGCTGCAG CAGGAGCTGG AGCTACTCAA TGCATATCAA 2460

AGCAAGATCA AGATGCAGGC GGAGGCCCAG CATGACCGGG AGCTCCGAGA GCTAGAGCAG 2520

AGGGTCTCCC TCCGCAGAGC ACTCTTGGAG CAAAAGATTG AAGAAGAGAT GTTGGCCTTG 2580

CAGAATGAGC GCACAGAACG AATACGAAGC CTGCTGGAGC GTCAAGCCAG AGAAATTGAA 2640

GCTTTTGACT CTGAGAGCAT GAGGCTAGGT TTTAGTAACA TGGTCCTTTC CAATCTCTCC 2700

CCTGAGGCAT TCAGCCACAG CTACCCTGGA GCTTCGGGTT GGTCCCATAA TCCCACGGGG 2760

GGCCCAGGCC CTCACTGGGG TCATCCCATG GGTGGCCCAC CTCAAGCTTG GGGCCACCCA 2820

ATGCAAGGTG GACCCCAGCC ATGGGGTCAT CCCTCGGGGC CAATGCAAGG GGTGCCTCGA 2880

GGCAGCGGCA TGGGAGTCCG CAACAGCCCC CAGGCTCTGA GGCGGCCAGC TTCTGGGGGA 2940

CGGACAGAGC AGGGCATGAG CAGGAGCACA AGTGTTACTT CACAAATATC CAATGGTTCA 3000

CACATGTCTT ATACTTAA 3018

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq...ekleelqkeisvlkklkhpn  57

         ++ l+eig+G++g+vy ar+++t+e+vaikk++++ +   ek+++++ke+++l+++khpn

Q: 28    FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKqsnEKWQDIIKEVKFLQRIKHPN  87

         67899*****************************988899********************

S: 58    iveylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHsk  117

          +ey +++l+e++ wlvmey+  Gs+sdl++ ++k++l+E +ia+i++++l++L+ylHs+

Q: 88    SIEYKGCYLREHTAWLVMEYCL-GSASDLLE-VHKKPLQEVEIAAITHGALQGLAYLHSH  145

         *********************7.********.****************************

S: 118   kviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqe.ekg  176

         ++iHrdika+niLlte g+VkL+dfg+a+  +      +++vgtpywmAPEvi ++ e +

Q: 146   NMIHRDIKAGNILLTEPGQVKLADFGSASIASP----ANSFVGTPYWMAPEVILAMdEGQ  201

         **************************9988887....69**************9887999

S: 177   YdekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvek  236

         Yd k+D+wslGIt+ielae++pP++++++++al++i++ne+p+l+s+ ++s+ f++fv++

Q: 202   YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSN-EWSDYFRNFVDS  260

         ********************************************888.************

S: 237   clqknpekRpsasellkhkFl  257

         clqk p++Rp+++ellkh F+

Q: 261   CLQKIPQDRPTSDELLKHMFV  281

         *******************97

Domain Sequence
(FASTA)

FTDLREIGHG SFGAVYFARD VRTNEVVAIK KMSYSGKQSN EKWQDIIKEV KFLQRIKHPN 60

SIEYKGCYLR EHTAWLVMEY CLGSASDLLE VHKKPLQEVE IAAITHGALQ GLAYLHSHNM 120

IHRDIKAGNI LLTEPGQVKL ADFGSASIAS PANSFVGTPY WMAPEVILAM DEGQYDGKVD 180

VWSLGITCIE LAERKPPLFN MNAMSALYHI AQNESPTLQS NEWSDYFRNF VDSCLQKIPQ 240

DRPTSDELLK HMFV 254

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013