EKS-SAH-00432

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00432

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	415.2	1.4E-124	26	321	296

Status

Unreviewed

Ensembl Protein

ENSSHAP00000006368

UniProt Accession

G3VT63;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPK9

Gene Synonyms/Alias

MAPK9;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000005542	ENSSHAP00000006368	ENSSHAT00000006423

Organism

Sarcophilus harrisii

Functional Description

Protein Length

429

Protein Sequence
(FASTA)

MSDNKCDSHF YSVQVADSTF TVLKRYQQLK PIGSGAQGIV CAAFDTVVGI NVAVKKLSRP 60

FQNQTHAKRA YRELVLLKCV NHKNIISLLN VFTPQKSLEE FQDVYLVMEL MDANLCQVIH 120

MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTACTNF 180

MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMGELVK GCVIFQGTDH IDQWNKVIEQ 240

LGTPSSDFMK KLQPTVRNYV ENRPKYPGIK FEELFPDWIF PSESERDKLK TSQARDLLSK 300

MLVIDPDKRI SVDEALRHPY ITVWYDPAEA EAPPPQIYDA QLEEREHAIE EWKELIYKEV 360

MDWEERSKNG VVKDQPSDAA VNSNTTPSQS SSINDISSMS TEQTLASDTD SSLDALTGPI 420

EDEDIQNLT 429

Nucleotide Sequence
(FASTA)

ATGAGTGACA ATAAATGTGA TAGTCATTTT TATAGTGTGC AAGTTGCAGA TTCAACTTTC 60

ACAGTACTGA AACGTTACCA GCAATTAAAA CCAATAGGAT CTGGAGCTCA GGGAATTGTT 120

TGCGCTGCTT TTGATACAGT TGTTGGAATA AATGTTGCTG TCAAGAAATT AAGTCGACCA 180

TTTCAGAATC AGACTCATGC AAAGAGAGCT TACCGTGAGC TTGTTCTGTT AAAATGTGTC 240

AATCATAAAA ATATAATTAG CTTATTGAAT GTGTTCACAC CACAGAAATC TCTAGAAGAA 300

TTTCAAGATG TGTATTTGGT TATGGAATTA ATGGATGCTA ATTTATGCCA AGTGATTCAT 360

ATGGAATTGG ACCATGAAAG AATGTCTTAC CTTCTTTATC AAATGCTCTG TGGTATTAAA 420

CACCTCCATT CAGCTGGTAT AATACACCGA GATTTGAAAC CCAGCAATAT AGTAGTAAAG 480

TCAGATTGTA CACTCAAGAT CCTTGATTTT GGCCTGGCAC GGACAGCATG TACTAATTTT 540

ATGATGACTC CATATGTAGT TACACGGTAT TATAGAGCAC CTGAAGTTAT CTTGGGGATG 600

GGATACAAAG AAAACGTTGA TATCTGGTCA GTGGGGTGCA TCATGGGAGA ACTGGTGAAA 660

GGTTGTGTGA TATTCCAAGG CACTGATCAT ATTGATCAGT GGAATAAAGT AATTGAGCAG 720

TTAGGAACAC CATCATCAGA CTTTATGAAG AAATTACAGC CAACTGTGAG GAATTATGTA 780

GAAAACAGGC CGAAATATCC TGGTATCAAA TTTGAAGAGC TTTTCCCTGA TTGGATATTC 840

CCATCAGAAT CTGAACGAGA TAAACTGAAA ACAAGTCAAG CTAGAGATTT GTTATCAAAA 900

ATGCTCGTAA TAGATCCTGA CAAGCGAATT TCTGTCGATG AAGCCTTACG GCACCCATAT 960

ATTACTGTTT GGTATGATCC TGCTGAAGCA GAAGCACCAC CACCTCAAAT TTATGATGCC 1020

CAGTTAGAAG AACGAGAACA TGCTATTGAA GAATGGAAAG AACTAATATA CAAAGAAGTA 1080

ATGGACTGGG AAGAAAGAAG CAAGAATGGT GTGGTAAAAG ATCAACCTTC AGATGCAGCA 1140

GTAAATAGCA ACACCACTCC TTCTCAGTCC TCATCTATCA ATGACATTTC ATCCATGTCA 1200

ACAGAGCAGA CATTGGCTTC AGATACAGAC AGCAGCCTGG ATGCCTTGAC AGGACCCATT 1260

GAAGATGAGG ACATCCAAAA CCTGACATGA 1290

Domain Profile

S: 1     yeslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNi  60

         y++lkp+g+Ga+g+v++a+d+  + +va+kklsrpfq++t+akr++REl llk+++h+Ni

Q: 26    YQQLKPIGSGAQGIVCAAFDTVVGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNI  85

         899*********************************************************

S: 61    iklldvftpeeeleelkdvYlvtelmetdLkkviksqklsdehiklllyqilrglkylHs  120

         i+ll+vftp+++lee++dvYlv+elm+++L++vi+++ l++e++++llyq+l+g+k+lHs

Q: 86    ISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIHME-LDHERMSYLLYQMLCGIKHLHS  144

         ************************************9.**********************

S: 121   anviHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslke  180

         a++iHrDlKPsN++v++dc+lkildFGlar+a ++ +  +t+yv+tr+YraPe++l  +

Q: 145   AGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM--MTPYVVTRYYRAPEVILG-MG  201

         ********************************99976..*****************9.99

S: 181   ytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseearnyi  240

         y+++vDiWsvGCI++El++g ++f+g+d+idq++k++e+lgtps++f+kk++  ++rny+

Q: 202   YKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSSDFMKKLQP-TVRNYV  260

         *****************************************************.5*****

S: 241   kslpkkkkkdfeelfpk............aseealdLleklLvldpdkRisveeaLehpY  288

         +++pk++  +feelfp+            ++++a+dLl+k+Lv+dpdkRisv+eaL+hpY

Q: 261   ENRPKYPGIKFEELFPDwifpseserdklKTSQARDLLSKMLVIDPDKRISVDEALRHPY  320

         ************************************************************

S: 289   l  289

Q: 321   I  321

Domain Sequence
(FASTA)

YQQLKPIGSG AQGIVCAAFD TVVGINVAVK KLSRPFQNQT HAKRAYRELV LLKCVNHKNI 60

ISLLNVFTPQ KSLEEFQDVY LVMELMDANL CQVIHMELDH ERMSYLLYQM LCGIKHLHSA 120

GIIHRDLKPS NIVVKSDCTL KILDFGLART ACTNFMMTPY VVTRYYRAPE VILGMGYKEN 180

VDIWSVGCIM GELVKGCVIF QGTDHIDQWN KVIEQLGTPS SDFMKKLQPT VRNYVENRPK 240

YPGIKFEELF PDWIFPSESE RDKLKTSQAR DLLSKMLVID PDKRISVDEA LRHPYI 296

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR008351	; MAPK_JNK.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01772

; JNKMAPKINASE.

Created Date

20-Feb-2013