EKS-SAH-00350

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00350

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/MLK	295.9	2.8E-88	244	500	257

Status

Unreviewed

Ensembl Protein

ENSSHAP00000006823

UniProt Accession

G3VUG8;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000005927	ENSSHAP00000006823	ENSSHAT00000006882

Organism

Sarcophilus harrisii

Functional Description

Protein Length

613

Protein Sequence
(FASTA)

MEEGSKADVN AQDNEDHVPL HFCSRFGHHD IVKFLLQSDS DVQPHIANIY GDTPLHLACY 60

NGKFEVAKEI IQVSGTESLA KENIFSETAF HSACTYGKSI ELVKFLLDQN ILSINHQGRD 120

GHTGLHSACY HGHIRLVQFL LDNGADMNLV ACDPSRSSGE KDEQTCLMWA YEKGHDAIVT 180

LLKHYKRPQD ELPCNEYSQP GGDGSYVSVP SPLGKIKSMT KEKADVLLLR AGLPSHFQLQ 240

LSEIEFHEII GSGSFGKVYK GRCRNKIVAI KRYRAHTYCS KSDVDMFCRE VSILCRLNHP 300

CVIQFVGACL NDPSQFAIVT QYISGGSLFS LLHEQKRILD LQSKLIIAVD VAKGMEYLHN 360

LTQPIIHRDL NSHNILLYED GHAVVADFGE SRFLQSLDED NMTKQPGNLR WMAPEIFTQC 420

TRYTIKADVF SYALCLWELL TGEIPFAHLK PAAAAADMAY HHIRPPIGYS IPKPISSLLM 480

RGWNACPEGR PEFSEVVTKL EECLCNIELM SPSSSNSSGS LSPSSSSDCL ASRGGPSRSH 540

VAALRSRFEL EYALNARSCM YWSQSPGQIL AQGPSLEDMR RNFRFPAIDK NGYVSDPMSA 600

MHFPGPGGLE ESG 613

Nucleotide Sequence
(FASTA)

ATGGAAGAAG GCAGCAAAGC AGATGTGAAT GCCCAAGATA ATGAAGACCA TGTACCTCTC 60

CATTTCTGCT CTCGATTTGG ACACCATGAT ATTGTAAAAT TTCTGCTCCA AAGTGATTCT 120

GATGTTCAGC CACACATTGC TAATATCTAT GGAGACACAC CTTTGCACTT GGCTTGCTAC 180

AATGGAAAAT TTGAAGTTGC CAAGGAAATA ATTCAAGTGT CAGGAACAGA AAGTCTGGCA 240

AAGGAAAACA TTTTTAGTGA AACAGCTTTT CACAGTGCTT GTACATACGG CAAAAGTATC 300

GAACTCGTTA AATTTCTTCT CGACCAAAAC ATCCTAAGCA TCAATCATCA AGGAAGAGAT 360

GGACACACTG GATTACACTC TGCTTGCTAC CATGGACACA TCCGCCTGGT GCAGTTCTTA 420

CTGGATAATG GAGCAGATAT GAATCTGGTA GCCTGTGATC CCAGCAGGTC AAGTGGTGAA 480

AAAGATGAGC AGACTTGTTT GATGTGGGCT TATGAAAAAG GGCACGACGC CATCGTCACG 540

CTCCTGAAAC ATTATAAGAG GCCTCAGGAT GAATTGCCCT GTAATGAATA TTCTCAGCCA 600

GGAGGAGATG GCTCCTATGT TTCTGTTCCG TCTCCCCTGG GGAAAATTAA AAGCATGACT 660

AAAGAAAAGG CGGATGTCCT CCTCCTGCGG GCAGGGCTGC CTTCCCACTT CCAGCTTCAG 720

CTCTCTGAAA TTGAATTCCA TGAAATTATT GGCTCAGGGT CTTTTGGAAA AGTATACAAA 780

GGCAGATGCA GGAACAAAAT AGTGGCTATC AAACGCTATC GGGCCCACAC GTACTGCTCC 840

AAGTCCGACG TGGACATGTT CTGCAGGGAG GTGTCTATCC TCTGCCGACT CAACCATCCC 900

TGCGTGATCC AGTTTGTCGG AGCCTGCTTG AACGATCCCA GCCAATTCGC CATCGTCACC 960

CAGTACATAT CAGGGGGGTC CCTGTTCTCC CTTCTCCACG AGCAGAAGAG GATTCTGGAC 1020

CTACAGTCCA AACTGATCAT TGCTGTGGAC GTCGCCAAAG GCATGGAGTA CCTGCACAAC 1080

CTGACCCAGC CCATCATCCA CCGGGACTTG AACAGCCACA ACATTCTCCT CTATGAAGAT 1140

GGCCATGCTG TCGTAGCCGA CTTTGGAGAA TCAAGATTCC TGCAGTCTCT GGATGAGGAC 1200

AACATGACAA AACAACCTGG GAACCTGCGC TGGATGGCCC CTGAGATCTT CACCCAGTGC 1260

ACGCGGTACA CCATCAAAGC GGACGTCTTC AGCTACGCGC TGTGCCTCTG GGAGCTCCTC 1320

ACCGGCGAAA TCCCTTTTGC GCACCTCAAG CCAGCCGCAG CAGCTGCCGA CATGGCTTAC 1380

CACCACATCC GACCTCCCAT CGGCTATTCC ATTCCCAAAC CCATCTCGTC TTTGTTAATG 1440

AGAGGCTGGA ACGCGTGTCC TGAAGGAAGA CCAGAATTTT CTGAAGTCGT GACAAAATTG 1500

GAAGAATGCC TTTGCAACAT TGAGCTGATG TCGCCTTCAT CAAGTAACAG CAGTGGGTCC 1560

CTGTCTCCTT CCTCGTCCTC TGATTGCCTG GCGAGCCGCG GAGGCCCCAG CAGGAGTCAC 1620

GTCGCTGCCC TCCGGAGCCG CTTTGAGCTA GAGTACGCCC TGAATGCCAG ATCCTGCATG 1680

TACTGGTCTC AGAGCCCTGG ACAGATCCTC GCCCAAGGTC CATCTCTGGA AGACATGAGG 1740

AGAAACTTTC GGTTCCCTGC GATTGACAAA AATGGCTACG TGTCGGACCC CATGAGCGCC 1800

ATGCACTTCC CGGGCCCCGG CGGCTTGGAG GAGAGCGGCT GA 1842

Domain Profile

S: 1     ieleeligsgafgkvykakwrkkevavKklreeaee.kekleklereakllsklshpnii  59

         ie++e+igsg+fgkvyk+++r+k va+K++r+++++ k+++++++re+++l++l+hp++i

Q: 244   IEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRAHTYCsKSDVDMFCREVSILCRLNHPCVI  303

         5899*****************************9998999********************

S: 60    ellGvcleepn.lllvmeyveggsLsnvlhekskreidlevlvswalqiArGmaYLhsea  118

         +++G+cl++p+ +++v++y++ggsL+++lhe +kr +dl+  + +a+++A+Gm+YLh+ +

Q: 304   QFVGACLNDPSqFAIVTQYISGGSLFSLLHE-QKRILDLQSKLIIAVDVAKGMEYLHNLT  362

         ***********99******************.99*************************6

S: 119   pkkiihrdLksknvLlseekktlkicdFGtarelsk..stkmsaa.gtlawmaPEvl.ke  174

         + +iihrdL+s+n+Ll  e+ ++ ++dFG++r+l++  +++m+++ g+l+wmaPE++ ++

Q: 363   Q-PIIHRDLNSHNILL-YEDGHAVVADFGESRFLQSldEDNMTKQpGNLRWMAPEIFtQC  420

         6.9*************.9*****************99877777777**************

S: 175   ekvseksDvwSygvvLWelltrevPykdlselaiaykvalkglrlpipsscpeklkkLmk  234

         ++++ k+Dv+Sy+++LWellt+e+P+++l+++a+a+++a++++r+pi+ s+p+++++L+

Q: 421   TRYTIKADVFSYALCLWELLTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLM  480

         ************************************************************

S: 235   ecwnedpekRpsfseivksl  254

         + wn++pe Rp+fse+v++l

Q: 481   RGWNACPEGRPEFSEVVTKL  500

         ****************9875

Domain Sequence
(FASTA)

IEFHEIIGSG SFGKVYKGRC RNKIVAIKRY RAHTYCSKSD VDMFCREVSI LCRLNHPCVI 60

QFVGACLNDP SQFAIVTQYI SGGSLFSLLH EQKRILDLQS KLIIAVDVAK GMEYLHNLTQ 120

PIIHRDLNSH NILLYEDGHA VVADFGESRF LQSLDEDNMT KQPGNLRWMA PEIFTQCTRY 180

TIKADVFSYA LCLWELLTGE IPFAHLKPAA AAADMAYHHI RPPIGYSIPK PISSLLMRGW 240

NACPEGRPEF SEVVTKL 257

Keyword

ANK repeat; Complete proteome; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

InterPros

IPR002110	; Ankyrin_rpt.
IPR020683	; Ankyrin_rpt-contain_dom.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.

Pfam

PF12796	; Ank_2; 2.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00248

; ANK; 5.

Prosites

PS50297	; ANK_REP_REGION; 1.
PS50088	; ANK_REPEAT; 3.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

PR01415

; ANKYRIN.

Created Date

20-Feb-2013