EKS-SAH-00198

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00198

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	490.0	1.7E-147	4	287	284

Status

Unreviewed

Ensembl Protein

ENSSHAP00000007227

UniProt Accession

G3VVM1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL2

Gene Synonyms/Alias

CDKL2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000006280	ENSSHAP00000007227	ENSSHAT00000007289
ENSSHAG00000006280	ENSSHAP00000007226	ENSSHAT00000007288

Organism

Sarcophilus harrisii

Functional Description

Protein Length

561

Protein Sequence
(FASTA)

MEKYENLGLV GEGSYGAVMK CKNKNNGRIV AIKKFLESED NKTVKKIVTR EIKLLKQLRH 60

ENLVTLLEAF KKRKRWYLVF EFVDHTILDD LDLFPNGLEY PNVQKYLFQI IKGIEFCHNH 120

NIIHRDIKPE NILISKSGVV KLCDFGFARM LGAPGEVYTD YVATRWYRAP ELLVGDIKYG 180

KAVDIWAIGC LLIEMFTGQP IFPGDSDIDQ LYHIVKCLGN LIPRHQELFY KNQLLAKVKL 240

PEAEVAQSLE SRFPKLPTVV IDIAKKCLQI DPDKRPFCDE LLHHDFFNQD GFAERFSEEL 300

KLKIQKDARE LSSLKLSKVS KKEKSDSSSK ERKTLVTKDV NADPATRNSK LIKIKPPKGN 360

SEKIEKPSRT SHPSCCPDNG MNQIRTIYPG TFGFPSNGSI DYTKNPSMVI PPVIHNISSI 420

ACNVNSGMGS ILGGHAYRVD EKSKKNYIPL VKLGSHYNAN LTTLVSNEKN ILQTNKKRWE 480

FSKTEVHFPE LNYHLPEVRG IEGILRNARL IKKDNKNFSE SWIPSLAAFE LYLPNMAFHQ 540

VPGSSLPDAQ EASFPQVEHP N 561

Nucleotide Sequence
(FASTA)

ATGGAGAAAT ATGAGAACCT AGGTCTGGTT GGTGAAGGCA GCTATGGAGC AGTGATGAAG 60

TGTAAGAATA AAAATAATGG AAGAATAGTG GCCATCAAGA AATTCCTGGA GAGTGAAGAT 120

AATAAAACAG TTAAAAAAAT TGTTACTCGA GAAATCAAAT TATTGAAGCA ATTGAGGCAT 180

GAAAATTTGG TGACTCTCCT GGAAGCGTTT AAGAAAAGGA AACGATGGTA CCTAGTATTT 240

GAATTTGTAG ATCACACTAT ACTTGATGAC TTGGACCTCT TTCCAAATGG ACTGGAATAC 300

CCAAACGTTC AAAAGTATTT GTTTCAGATA ATTAAAGGAA TTGAATTTTG TCATAATCAC 360

AATATTATAC ACAGAGATAT AAAGCCAGAG AACATACTGA TCTCCAAGTC TGGAGTAGTG 420

AAGCTGTGTG ACTTTGGATT TGCTCGCATG TTGGGAGCAC CTGGGGAAGT GTACACTGAT 480

TATGTGGCAA CTCGTTGGTA CAGAGCTCCA GAGCTTTTGG TTGGAGACAT AAAGTATGGC 540

AAGGCTGTTG ATATATGGGC CATTGGTTGT TTGTTGATTG AAATGTTCAC AGGGCAGCCC 600

ATTTTTCCTG GGGATTCTGA TATTGATCAA CTGTATCATA TTGTGAAATG TTTGGGGAAT 660

TTAATTCCAA GACATCAGGA ACTGTTCTAT AAGAACCAGC TCCTTGCCAA AGTGAAATTG 720

CCTGAAGCTG AAGTAGCCCA GTCTCTTGAA AGCCGCTTCC CAAAGCTCCC CACAGTGGTG 780

ATTGATATAG CAAAGAAATG TTTACAGATT GATCCTGACA AAAGGCCCTT CTGTGATGAG 840

CTCCTGCACC ATGACTTCTT TAACCAGGAT GGGTTTGCTG AGAGATTTTC TGAGGAGTTA 900

AAATTAAAGA TACAGAAAGA TGCCAGAGAA CTTTCTTCAT TAAAATTATC TAAAGTTAGT 960

AAAAAGGAAA AATCTGATTC TTCAAGTAAA GAAAGAAAAA CACTTGTTAC AAAGGATGTC 1020

AATGCTGATC CTGCAACTAG GAATTCTAAA TTGATCAAAA TAAAGCCACC AAAAGGCAAT 1080

AGTGAAAAGA TTGAAAAACC CAGCAGAACA TCCCATCCCA GCTGTTGCCC TGACAATGGA 1140

ATGAATCAGA TAAGGACAAT TTATCCAGGC ACCTTTGGAT TCCCCAGCAA CGGCAGTATA 1200

GATTACACAA AGAATCCCAG CATGGTGATT CCTCCAGTTA TACACAATAT TTCTAGCATT 1260

GCTTGCAATG TAAATTCAGG AATGGGGTCC ATTCTAGGAG GTCATGCTTA CAGGGTGGAT 1320

GAAAAATCTA AAAAGAACTA TATTCCACTT GTTAAATTGG GTAGCCATTA TAATGCTAAC 1380

CTGACTACAT TGGTCTCTAA TGAAAAGAAC ATTCTTCAGA CAAACAAAAA AAGATGGGAA 1440

TTCTCCAAGA CAGAGGTTCA TTTTCCTGAA CTAAATTATC ACCTCCCTGA GGTCAGAGGA 1500

ATCGAAGGCA TACTTCGAAA TGCTAGACTG ATAAAGAAAG ACAACAAAAA CTTTTCAGAA 1560

TCTTGGATCC CATCTCTGGC TGCTTTTGAG TTGTACCTCC CTAATATGGC CTTCCATCAG 1620

GTACCAGGGT CCTCCCTGCC AGATGCTCAA GAGGCCAGCT TCCCTCAAGT AGAACACCCA 1680

AACTGA 1686

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lg vGeGsyG v+kc+nk+ g+ivaikkflesed+k+vkki +reikllkql+henl

Q: 4     YENLGLVGEGSYGAVMKCKNKNNGRIVAIKKFLESEDNKTVKKIVTREIKLLKQLRHENL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         v lle+f+++k++ylvfe+vd+t+ld+l+ +pnG+e+  v+k+l+qi+k+iefch++nii

Q: 64    VTLLEAFKKRKRWYLVFEFVDHTILDDLDLFPNGLEYPNVQKYLFQIIKGIEFCHNHNII  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenilisksgvvklcdfGfar+l apg+vytdyvatrwyrapellvgd+kyGk+v

Q: 124   HRDIKPENILISKSGVVKLCDFGFARMLGAPGEVYTDYVATRWYRAPELLVGDIKYGKAV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+waiGcll+e++tG+p+fpg+sd+dqly+i+k+lG+liprhq++f+kn+++a vklpe

Q: 184   DIWAIGCLLIEMFTGQPIFPGDSDIDQLYHIVKCLGNLIPRHQELFYKNQLLAKVKLPEA  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         e ++sle+++pkl +v++d++kkcl++dp++r +c+ell+h++f

Q: 244   EVAQSLESRFPKLPTVVIDIAKKCLQIDPDKRPFCDELLHHDFF  287

         ******************************************98

Domain Sequence
(FASTA)

YENLGLVGEG SYGAVMKCKN KNNGRIVAIK KFLESEDNKT VKKIVTREIK LLKQLRHENL 60

VTLLEAFKKR KRWYLVFEFV DHTILDDLDL FPNGLEYPNV QKYLFQIIKG IEFCHNHNII 120

HRDIKPENIL ISKSGVVKLC DFGFARMLGA PGEVYTDYVA TRWYRAPELL VGDIKYGKAV 180

DIWAIGCLLI EMFTGQPIFP GDSDIDQLYH IVKCLGNLIP RHQELFYKNQ LLAKVKLPEA 240

EVAQSLESRF PKLPTVVIDI AKKCLQIDPD KRPFCDELLH HDFF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013