EKS-SAH-00222

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00222

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PDK1	420.7	2.9E-126	58	318	261

Status

Unreviewed

Ensembl Protein

ENSSHAP00000009016

UniProt Accession

G3W0R2;

Protein Name

Protein Synonyms/Alias

Gene Name

PDPK1

Gene Synonyms/Alias

PDPK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000007805	ENSSHAP00000009017	ENSSHAT00000009091
ENSSHAG00000007805	ENSSHAP00000009016	ENSSHAT00000009090

Organism

Sarcophilus harrisii

Functional Description

Protein Length

531

Protein Sequence
(FASTA)

MVRNHTDSST PPVIVPCSSR QGSTMDGTTA EPRSNSNSLP QHSGQQLPQP RKKRPEDFKF 60

GKILGEGSFS TVVLARELAT SREYAIKILE KRHIIKENKV PYVTRERDVM SRLDHPFFVK 120

LYFTFQDDEK LYFGLSYAKN GELLKYIRKI GSFDETCTRF YTAEIVSALE YLHGKGIIHR 180

DLKPENILLN EDMHIQITDF GTAKVLSPDS KQARANSFVG TAQYVSPELL TEKSACKSSD 240

LWALGCIIYQ LVAGLPPFRA GNEYLIFQKI IKLEYDFPEK FFPKAKDLVE KLLVLDSTKR 300

LGCEEMDGYG PLKDHSFFES ITWEDLHHQT PPKLTAYLPA MSEDDEDCYG NYDNLLSQFG 360

CMQVSSSTSS HSLSASETSL PQRSGSNIDQ YIHDLDNNSF ELDLQFSEDE KKLLLEKQAS 420

GNPWHQFVEN NLILKMGPVD KRKGLFARRR QLLLTEGPHL YYVDPVNKVL KGEIPWSQEL 480

RPEAKNFKTF FVHTPNRTYY LMDPSGNAHK WCKKIHEVWR HRYQNHPNTA V 531

Nucleotide Sequence
(FASTA)

ATGGTGAGAA ACCATACAGA TTCCAGCACT CCCCCTGTCA TCGTTCCCTG TAGTAGCAGA 60

CAGGGGTCTA CAATGGATGG CACTACAGCT GAGCCAAGGT CTAATTCCAA TTCCTTACCA 120

CAACATTCAG GACAGCAGCT ACCACAGCCT CGAAAGAAAC GGCCAGAAGA CTTCAAGTTT 180

GGAAAAATCC TTGGTGAAGG ATCTTTCTCA ACAGTTGTCT TGGCCCGGGA ATTGGCAACT 240

TCTAGAGAAT ATGCTATTAA AATCCTAGAG AAACGGCATA TCATAAAAGA GAACAAGGTA 300

CCATATGTAA CCAGAGAAAG AGATGTAATG TCCCGCCTGG ATCACCCTTT CTTTGTAAAA 360

CTTTACTTCA CATTTCAGGA CGATGAAAAG CTGTATTTTG GCCTTAGTTA TGCCAAAAAT 420

GGAGAGCTAC TTAAATATAT TCGAAAGATT GGTTCTTTTG ATGAGACTTG CACCAGATTT 480

TATACTGCTG AAATTGTGTC TGCTTTAGAA TATTTGCATG GAAAGGGAAT TATTCACAGG 540

GACCTTAAAC CAGAGAACAT TTTATTAAAT GAAGATATGC ACATTCAGAT TACAGATTTT 600

GGAACAGCAA AAGTATTATC TCCAGATAGT AAACAAGCCA GGGCTAATTC ATTTGTAGGA 660

ACAGCACAAT ATGTTTCTCC AGAGCTGCTT ACAGAAAAAT CAGCATGTAA AAGTTCAGAC 720

CTCTGGGCTC TCGGATGTAT AATATATCAA CTTGTAGCAG GATTACCACC ATTTAGAGCA 780

GGAAATGAAT ATCTTATATT TCAGAAGATA ATTAAATTGG AATATGACTT TCCAGAAAAA 840

TTCTTTCCTA AGGCAAAAGA TCTTGTGGAA AAACTTTTAG TTTTAGATTC CACAAAGCGA 900

TTAGGCTGTG AAGAAATGGA TGGGTATGGA CCCCTTAAAG ATCACTCATT CTTTGAATCT 960

ATAACATGGG AGGATCTACA TCATCAGACG CCCCCAAAGC TGACAGCATA CTTACCTGCT 1020

ATGTCTGAAG ATGATGAAGA CTGCTATGGA AATTATGACA ATCTTCTAAG CCAATTTGGC 1080

TGCATGCAAG TTTCATCTTC GACTTCTTCA CATTCATTAT CTGCTTCGGA GACTAGTCTG 1140

CCCCAGAGAT CAGGCAGCAA TATTGACCAA TACATTCATG ATCTGGACAA TAATTCTTTT 1200

GAGCTGGACT TACAGTTTTC TGAGGATGAG AAGAAATTAT TATTGGAGAA GCAGGCCAGT 1260

GGAAACCCAT GGCACCAATT TGTAGAAAAC AACTTGATAC TAAAAATGGG TCCAGTAGAT 1320

AAACGAAAGG GTTTATTTGC ACGCCGTCGT CAGTTGCTCC TTACAGAAGG ACCACATTTG 1380

TATTATGTGG ACCCTGTCAA CAAAGTTTTG AAAGGAGAGA TTCCTTGGTC ACAAGAACTT 1440

CGGCCAGAAG CCAAGAATTT TAAGACCTTT TTTGTTCACA CACCTAACAG GACATATTAC 1500

CTGATGGACC CAAGTGGGAA TGCTCATAAG TGGTGCAAAA AGATACATGA AGTTTGGCGG 1560

CACAGATACC AGAACCATCC GAATACTGCT GTCTAG 1596

Domain Profile

S: 1     fkfekelgeGsystvvlarekeskkeyaikvlekryiikekkvkyvtrekevlaklnehp  60

         fkf+k+lgeGs+stvvlare+++++eyaik+lekr+iike+kv+yvtre++v+++l +hp

Q: 58    FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRL-DHP  116

         89******************************************************.9**

S: 61    givkLyatfqDeeslyfvleyakkGdllellkkvgsfdeactryyaaellsaleflhkkg  120

         ++vkLy+tfqD+e+lyf l+yak+G+ll++++k+gsfde+ctr+y+ae++sale+lh kg

Q: 117   FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG  176

         ************************************************************

S: 121   iihrDlkpeniLldkdgkilitDfGsakvlepklkedskkeeeesarsksfvGtaeyvsP  180

         iihrDlkpeniLl++d++i+itDfG+akvl+p++k+         ar++sfvGta+yvsP

Q: 177   IIHRDLKPENILLNEDMHIQITDFGTAKVLSPDSKQ---------ARANSFVGTAQYVSP  227

         ******************************999998.........9**************

S: 181   elLtdsevskssDlWalgcilyqllaGkpPfraeneylifkkilkleyafpegfpekakd  240

         elLt+++++kssDlWalgci+yql+aG+pPfra neylif+ki+kley+fpe+f++kakd

Q: 228   ELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKAKD  287

         ************************************************************

S: 241   lveklLvkdakerltlee......ikahkff  265

         lveklLv d ++rl++ee      +k+h ff

Q: 288   LVEKLLVLDSTKRLGCEEmdgygpLKDHSFF  318

         ******************9***********9

Domain Sequence
(FASTA)

FKFGKILGEG SFSTVVLARE LATSREYAIK ILEKRHIIKE NKVPYVTRER DVMSRLDHPF 60

FVKLYFTFQD DEKLYFGLSY AKNGELLKYI RKIGSFDETC TRFYTAEIVS ALEYLHGKGI 120

IHRDLKPENI LLNEDMHIQI TDFGTAKVLS PDSKQARANS FVGTAQYVSP ELLTEKSACK 180

SSDLWALGCI IYQLVAGLPP FRAGNEYLIF QKIIKLEYDF PEKFFPKAKD LVEKLLVLDS 240

TKRLGCEEMD GYGPLKDHSF F 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013