EKS-SAH-00176

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00176

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PKA	445.0	8.1E-134	1	249	249

Status

Unreviewed

Ensembl Protein

ENSSHAP00000009194

UniProt Accession

G3W189;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKX

Gene Synonyms/Alias

PRKX;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000007958	ENSSHAP00000009194	ENSSHAT00000009272

Organism

Sarcophilus harrisii

Functional Description

Protein Length

304

Protein Sequence
(FASTA)

VGTGTFGRVH LVKERTAKHY FALKVMSIPD VIRLKQEQHV HNEKSVLKEV NHPFLIRLYW 60

TYHDERFLYM LMEYVPGGEL FSYLRNMGRF NNSTGLFYSA EIICAIEYLH SKEIVYRDLK 120

PENILLDKEG HIKLTDFGFA KKLVDRTWTL CGTPEYLAPE VIQSKGHGRA VDWWALGILI 180

FEMLSGFPPF FDDNPFGIYQ KILAGKIDFP RHLDLYVKDL IKKLLVVDRT RRLGNMKNGA 240

DDVKRHRWFR SVDWDAVPQR KLKPPIVPKV SNDGDTSNFE AYPEDDWNKT PPVPPKDLEI 300

FKNF 304

Nucleotide Sequence
(FASTA)

GTAGGCACAG GTACCTTTGG ACGAGTTCAT CTAGTGAAGG AAAGAACAGC CAAACATTAT 60

TTTGCCTTGA AGGTGATGAG CATTCCGGAT GTCATTCGGC TAAAGCAAGA ACAGCATGTG 120

CATAATGAAA AGTCAGTTCT GAAAGAAGTC AACCATCCAT TTCTCATCAG ATTATATTGG 180

ACCTACCATG ATGAAAGATT TTTATATATG TTGATGGAAT ATGTTCCTGG AGGAGAACTT 240

TTCAGCTACT TGAGAAACAT GGGACGGTTT AATAACAGCA CAGGACTATT TTACTCTGCG 300

GAGATTATCT GTGCAATAGA ATATCTGCAC TCCAAAGAAA TAGTTTACAG AGATTTAAAA 360

CCTGAAAATA TATTATTAGA TAAAGAAGGC CATATCAAGC TCACTGATTT TGGATTTGCT 420

AAAAAGCTAG TAGACAGAAC ATGGACACTC TGTGGGACAC CAGAATACCT TGCTCCAGAA 480

GTCATACAAA GTAAAGGTCA CGGAAGAGCA GTAGACTGGT GGGCTCTGGG GATTCTGATA 540

TTTGAGATGC TGTCTGGATT TCCTCCATTT TTTGATGACA ACCCATTTGG CATCTATCAA 600

AAAATTCTTG CAGGCAAAAT AGATTTCCCC AGGCATTTGG ATCTCTATGT AAAAGACCTT 660

ATTAAGAAAC TTCTTGTGGT AGATAGGACA AGACGACTAG GAAACATGAA GAATGGAGCA 720

GACGATGTGA AAAGGCACCG GTGGTTCAGG TCTGTGGACT GGGATGCGGT ACCCCAGAGA 780

AAACTGAAGC CTCCTATAGT GCCGAAGGTT TCCAATGATG GTGATACATC TAATTTTGAA 840

GCTTATCCTG AAGATGACTG GAATAAGACA CCACCTGTGC CTCCTAAAGA CTTAGAAATC 900

TTTAAGAATT TCTGA 915

Domain Profile

S: 7     lGtGsfGrvelvrekeskkyyalkvlskekvvklkqvehvknekrvlkavefpflvklla  66

         +GtG+fGrv+lv+e+++k+y+alkv+s+ +v++lkq +hv+nek+vlk+v++pfl++l++

Q: 1     VGTGTFGRVHLVKERTAKHYFALKVMSIPDVIRLKQEQHVHNEKSVLKEVNHPFLIRLYW  60

         79**********************************************************

S: 67    sfkdesnlylvleyveGGelfsylrkvrrfsekaarfyaaeivlaleylhsldliyrdlk  126

         +++de++ly+++eyv+GGelfsylr+++rf+++++ fy+aei++a+eylhs++++yrdlk

Q: 61    TYHDERFLYMLMEYVPGGELFSYLRNMGRFNNSTGLFYSAEIICAIEYLHSKEIVYRDLK  120

         ************************************************************

S: 127   penllldkeGyikvtdfGfakkvkdrtwtlcGtpeylapeiiqskgynkavdwwalGvli  186

         pen+lldkeG+ik+tdfGfakk+ drtwtlcGtpeylape+iqskg+++avdwwalG+li

Q: 121   PENILLDKEGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILI  180

         ************************************************************

S: 187   yellaGyppffddqpikiyekivsgklkfpsklssdlkdllkkllqvdltkrlgnlkngv  246

         +e+l+G+ppffdd+p+ iy+ki++gk++fp++l+  +kdl+kkll+vd+t+rlgn+kng+

Q: 181   FEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDLYVKDLIKKLLVVDRTRRLGNMKNGA  240

         ************************************************************

S: 247   edikehkwf  255

         +d+k+h+wf

Q: 241   DDVKRHRWF  249

         ********9

Domain Sequence
(FASTA)

VGTGTFGRVH LVKERTAKHY FALKVMSIPD VIRLKQEQHV HNEKSVLKEV NHPFLIRLYW 60

TYHDERFLYM LMEYVPGGEL FSYLRNMGRF NNSTGLFYSA EIICAIEYLH SKEIVYRDLK 120

PENILLDKEG HIKLTDFGFA KKLVDRTWTL CGTPEYLAPE VIQSKGHGRA VDWWALGILI 180

FEMLSGFPPF FDDNPFGIYQ KILAGKIDFP RHLDLYVKDL IKKLLVVDRT RRLGNMKNGA 240

DDVKRHRWF 249

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013