EKS-SAH-00394

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00394

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	535.6	2.5E-161	93	350	258

Status

Unreviewed

Ensembl Protein

ENSSHAP00000009415

UniProt Accession

G3W1V9;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK3

Gene Synonyms/Alias

SGK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000008146	ENSSHAP00000009415	ENSSHAT00000009496
ENSSHAG00000008146	ENSSHAP00000009414	ENSSHAT00000009495

Organism

Sarcophilus harrisii

Functional Description

Protein Length

427

Protein Sequence
(FASTA)

MKIPAKRIFG DNFDPDFIKQ RRAGLNEFIQ NLVRHPELCN HPDVRAFLQM DSPRHQSDPS 60

EDEDERSIQK LLSTSQNINL GPSGNPHAKP TDFDFLKVIG KGSFGKVLLA KRKLDGKFYA 120

VKVLQKKIVL KRKEQKHIMA ERNVLLKNVK HPFLVGLHYS FQTTEKLYFV LDFVNGGELF 180

FHLQRERSFP EHRARFYAAE IASALGYLHS IKIVYRDLKP ENILLDSTGH VVLTDFGLCK 240

EGIAISDTTT TFCGTPEYLA PEVIRKQPYD NTVDWWCLGA VLYEMLYGLP PFYCRDVAEM 300

YENILHKPLN LRPGVSLTAW SILEELLEKD RQNRLGAKED FLEIQNHPFF ESLNWTDLVQ 360

KKIPPPFNPN VVGPDDIRNF DTAFTEEMVP YSVCISSDYS IVNASVLEAD DAFVGFSYAP 420

PSEDLFL 427

Nucleotide Sequence
(FASTA)

ATGAAGATTC CTGCCAAAAG AATATTTGGT GATAATTTTG ATCCAGATTT TATTAAACAG 60

AGAAGAGCAG GACTGAATGA ATTCATTCAG AATTTAGTTA GACATCCAGA GCTATGCAAC 120

CATCCAGATG TCAGAGCATT TCTTCAAATG GACAGTCCAC GACATCAGTC AGATCCTTCT 180

GAAGATGAGG ATGAAAGAAG TATTCAGAAG CTACTCTCTA CCTCACAGAA CATCAATCTG 240

GGACCATCTG GAAATCCTCA TGCCAAACCA ACAGATTTTG ATTTCCTAAA AGTTATTGGA 300

AAAGGCAGCT TTGGCAAGGT TCTTCTTGCA AAAAGGAAAC TAGATGGAAA ATTTTATGCT 360

GTCAAAGTGT TGCAGAAAAA AATTGTTTTG AAGAGAAAAG AGCAAAAACA CATCATGGCC 420

GAGCGTAATG TGCTCTTAAA AAATGTGAAA CATCCATTTT TGGTTGGATT ACATTATTCG 480

TTCCAGACAA CTGAAAAGCT TTATTTTGTT CTAGATTTTG TTAATGGAGG GGAGCTTTTC 540

TTCCACTTAC AAAGAGAACG ATCCTTTCCA GAACACAGAG CCAGATTTTA TGCTGCAGAA 600

ATTGCCAGTG CTTTGGGCTA TTTGCATTCC ATAAAAATAG TATACAGGGA CTTGAAGCCA 660

GAAAACATTC TTCTCGACTC AACGGGACAT GTCGTTTTAA CAGACTTTGG ATTGTGTAAA 720

GAAGGGATTG CTATATCTGA CACAACTACA ACATTTTGTG GGACACCAGA GTACCTTGCA 780

CCAGAAGTGA TCAGAAAACA ACCCTATGAC AATACTGTAG ATTGGTGGTG CCTTGGTGCT 840

GTTCTGTATG AAATGCTTTA TGGGTTGCCT CCATTTTATT GCCGAGATGT TGCTGAAATG 900

TATGAAAACA TACTTCATAA ACCCCTAAAT TTGAGGCCAG GAGTGAGCCT CACAGCCTGG 960

TCTATTCTGG AAGAACTTCT TGAAAAAGAC AGACAAAATC GACTTGGTGC CAAAGAAGAC 1020

TTTCTTGAAA TTCAAAATCA TCCTTTCTTT GAATCACTCA ACTGGACTGA CCTTGTACAA 1080

AAAAAGATTC CACCACCTTT TAATCCTAAT GTGGTTGGAC CAGATGATAT CAGGAACTTT 1140

GATACAGCCT TTACAGAAGA AATGGTTCCA TATTCTGTTT GTATATCTTC TGACTATTCT 1200

ATAGTGAATG CCAGTGTTTT GGAGGCAGAT GATGCATTTG TTGGTTTCTC TTATGCACCT 1260

CCTTCTGAAG ATTTGTTTTT GTAA 1284

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d+kfyavkvlqkk++lk+ke+khimaernvllknvkhp

Q: 93    FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLKRKEQKHIMAERNVLLKNVKHP  152

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt+eklyfvld+vnggelffhlqrersf+e+rarfyaaeiasalgylhs++

Q: 153   FLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIK  212

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds+ghvvltdfglcke+i+++dtt+tfcgtpeylapev+rk+pyd+t

Q: 213   IVYRDLKPENILLDSTGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNT  272

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfy+rdvaemy+nil+kpl+l+pg+s++a+++leellekdr+

Q: 273   VDWWCLGAVLYEMLYGLPPFYCRDVAEMYENILHKPLNLRPGVSLTAWSILEELLEKDRQ  332

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlgakedflei+nh+ff

Q: 333   NRLGAKEDFLEIQNHPFF  350

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KLDGKFYAVK VLQKKIVLKR KEQKHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TTEKLYFVLD FVNGGELFFH LQRERSFPEH RARFYAAEIA SALGYLHSIK 120

IVYRDLKPEN ILLDSTGHVV LTDFGLCKEG IAISDTTTTF CGTPEYLAPE VIRKQPYDNT 180

VDWWCLGAVL YEMLYGLPPF YCRDVAEMYE NILHKPLNLR PGVSLTAWSI LEELLEKDRQ 240

NRLGAKEDFL EIQNHPFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013