EKS-SAH-00204

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00204

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF2	457.4	3.0E-137	26	384	359

Status

Unreviewed

Ensembl Protein

ENSSHAP00000009460

UniProt Accession

G3W205;

Protein Name

Protein Synonyms/Alias

Gene Name

PINK1

Gene Synonyms/Alias

PINK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000008187	ENSSHAP00000009461	ENSSHAT00000009544
ENSSHAG00000008187	ENSSHAP00000009460	ENSSHAT00000009543

Organism

Sarcophilus harrisii

Functional Description

Protein Length

453

Protein Sequence
(FASTA)

IFTQKNKLLP DPLASRRWQG FRLEEYLIGQ FLGKGCNAAV YEAAMPAWPP QQQGPGLLLG 60

PDPATALPAE GEQSTGPKAE AFPLAIKMMW NISAGSSSEA IFSTMSQELV PASHVALSGE 120

YGAAVLRKEA VFPSPLLPSP SKGRLLSMLP RGSLSQRPGP LPDFPDLITS LFRNHHKCSQ 180

GLKSKCFIVS FNYPWTLHQY LQASPPSPRL ATMMLLQLLE GVDHLVQQGI AHRDLKSDNI 240

LVEFDSAGCP WLVITDFGCC LADESIGLQL PFTSWYVDRG GNSCLMAPEV STASPGPRVV 300

IDYSKADAWA VGAIAYEIFG LPNPFYGHGG AQLDSRSYCE SQLPALPESV PLDVRQLVKA 360

LLQRDASKRP SARVAANVLH LSLWGESILA MKNLKSDKMI GWLLHQSAAT LLTNRLMEGN 420

RVETKMKMCF LANLEYEVLC QAAFLLRSWR AAP 453

Nucleotide Sequence
(FASTA)

ATTTTCACCC AGAAAAACAA GCTTCTTCCT GATCCTCTGG CAAGTAGGCG TTGGCAGGGC 60

TTCCGGCTGG AGGAATACCT CATCGGACAG TTCCTTGGCA AGGGGTGCAA TGCTGCAGTG 120

TATGAGGCCG CCATGCCCGC CTGGCCCCCG CAGCAGCAAG GCCCCGGGCT CCTCCTGGGG 180

CCGGATCCTG CCACGGCCCT CCCTGCAGAA GGTGAGCAGA GCACCGGGCC CAAGGCCGAA 240

GCCTTTCCCT TGGCCATCAA GATGATGTGG AACATCTCGG CGGGTTCCTC CAGTGAAGCT 300

ATCTTCAGCA CCATGAGCCA GGAACTGGTT CCGGCCAGCC ACGTGGCCCT GTCTGGGGAG 360

TATGGGGCCG CTGTTCTCAG GAAGGAAGCA GTTTTCCCTT CCCCCTTACT CCCATCTCCC 420

AGCAAAGGCA GGCTCCTGAG CATGTTACCC AGAGGATCGC TCTCACAGCG TCCTGGCCCC 480

CTCCCAGATT TTCCCGATCT TATCACTTCA CTTTTCCGCA ATCACCACAA GTGCAGCCAG 540

GGGTTAAAGT CCAAATGCTT TATTGTCTCC TTCAACTACC CCTGGACCCT GCACCAGTAC 600

CTGCAGGCGA GCCCTCCAAG CCCCCGCCTC GCCACCATGA TGCTCCTGCA GCTGTTGGAA 660

GGAGTGGATC ACCTGGTTCA GCAGGGCATC GCACACAGGG ACTTAAAGTC AGACAACATC 720

CTCGTGGAAT TTGACTCAGC TGGCTGCCCC TGGTTGGTAA TAACAGATTT CGGTTGCTGT 780

CTGGCTGATG AGAGCATTGG CCTACAATTG CCTTTCACCA GTTGGTACGT GGACCGGGGA 840

GGAAATAGCT GCTTGATGGC TCCTGAGGTG TCAACAGCTT CTCCTGGTCC CAGGGTGGTG 900

ATCGACTACA GCAAAGCCGA CGCCTGGGCA GTGGGAGCGA TCGCCTATGA GATCTTTGGA 960

CTCCCCAATC CCTTCTATGG ACATGGTGGA GCCCAGCTGG ACAGCCGCAG TTACTGTGAG 1020

TCTCAGCTTC CCGCACTGCC TGAGAGTGTG CCCTTGGATG TGAGGCAGCT GGTAAAGGCG 1080

CTGCTCCAGA GGGATGCCAG CAAGAGACCA TCTGCCCGAG TAGCAGCAAA TGTGCTTCAC 1140

TTAAGCCTCT GGGGTGAAAG TATTTTAGCC ATGAAGAATC TGAAATCAGA CAAGATGATT 1200

GGCTGGCTTC TTCACCAATC AGCTGCCACT CTGCTGACTA ATCGGTTGAT GGAGGGAAAC 1260

AGGGTAGAAA CCAAAATGAA GATGTGCTTC TTGGCTAACC TGGAGTATGA AGTCCTCTGT 1320

CAAGCAGCGT TCCTTCTCCG GTCCTGGAGG GCAGCACCTT GA 1362

Domain Profile

S: 1     yligealgkgcnaavyeatlatldqelekakhlgll.gkevtvvlaeid.qesavaakkf  58

         ylig++lgkgcnaavyea +++ + + ++    gll g ++++ l+ ++ q   + a++f

Q: 26    YLIGQFLGKGCNAAVYEAAMPAWPPQQQG---PGLLlGPDPATALPAEGeQSTGPKAEAF  82

         99********************9987765...46554889988887665156679999**

S: 59    plaiklmfnieadssseallksmsqelvpasrvaldgeygav........pkllakhPni  110

         plaik+m+ni+a+sssea++++msqelvpas+val+geyga         p  l + P

Q: 83    PLAIKMMWNISAGSSSEAIFSTMSQELVPASHVALSGEYGAAvlrkeavfPSPLLPSPSK  142

         ****************************************98899999998888999999

S: 111   vrvlraf.idsvkllPdalldyPdalparl...ypeglgegktlylvmkrydqtlreyle  166

          r+l+++   s+   P+ l d+Pd++++ +   ++   g +   ++v  +y+ tl++yl+

Q: 143   GRLLSMLpRGSLSQRPGPLPDFPDLITSLFrnhHKCSQGLKSKCFIVSFNYPWTLHQYLQ  202

         99999883579**************9876511133455667889****************

S: 167   sqdrstrlaalllaqlleavdhlvkhgvahrdlksdnilveldddeiPvlviadfGCcla  226

            +s+rla+++l+qlle+vdhlv++g+ahrdlksdnilve+d+ ++P+lvi+dfGCcla

Q: 203   ASPPSPRLATMMLLQLLEGVDHLVQQGIAHRDLKSDNILVEFDSAGCPWLVITDFGCCLA  262

         ************************************************************

S: 227   dkvdglrlpyessevdkGGnaalmaPeistavpGpsavinyekadtWavGalayeifgls  286

         d+++gl+lp++s++vd+GGn++lmaPe+sta pGp++vi+y+kad+WavGa+ayeifgl

Q: 263   DESIGLQLPFTSWYVDRGGNSCLMAPEVSTASPGPRVVIDYSKADAWAVGAIAYEIFGLP  322

         ************************************************************

S: 287   nPfygegkaslesasyqeaqlPalpesvppelrqlvydllkreaskrvsadiaanvlqls  346

         nPfyg+g a+l+s+sy e+qlPalpesvp ++rqlv +ll+r+askr+sa++aanvl+ls

Q: 323   NPFYGHGGAQLDSRSYCESQLPALPESVPLDVRQLVKALLQRDASKRPSARVAANVLHLS  382

         ************************************************************

S: 347   lf  348

l+

Q: 383   LW  384

*9

Domain Sequence
(FASTA)

YLIGQFLGKG CNAAVYEAAM PAWPPQQQGP GLLLGPDPAT ALPAEGEQST GPKAEAFPLA 60

IKMMWNISAG SSSEAIFSTM SQELVPASHV ALSGEYGAAV LRKEAVFPSP LLPSPSKGRL 120

LSMLPRGSLS QRPGPLPDFP DLITSLFRNH HKCSQGLKSK CFIVSFNYPW TLHQYLQASP 180

PSPRLATMML LQLLEGVDHL VQQGIAHRDL KSDNILVEFD SAGCPWLVIT DFGCCLADES 240

IGLQLPFTSW YVDRGGNSCL MAPEVSTASP GPRVVIDYSK ADAWAVGAIA YEIFGLPNPF 300

YGHGGAQLDS RSYCESQLPA LPESVPLDVR QLVKALLQRD ASKRPSARVA ANVLHLSLW 359

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>