EKS-SAH-00146

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00146

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	518.3	5.9E-156	89	382	294

Status

Unreviewed

Ensembl Protein

ENSSHAP00000011876

UniProt Accession

G3W8X1;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38

Gene Synonyms/Alias

STK38;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000010192	ENSSHAP00000011876	ENSSHAT00000011974

Organism

Sarcophilus harrisii

Functional Description

Protein Length

465

Protein Sequence
(FASTA)

MAMTGSTPCS SMSNHTKERV TMTKVTLENF YSNLIAQHEE REMRQKKLEK VMEEEGLKDE 60

EKRLRRSAHA RKETEFLRLK RTRLGLEDFE SLKVIGRGAF GEVRLVQKKD TGHVYAMKIL 120

RKADMLEKEQ VGHIRAERDI LVEADSLWVV KMFYSFQDKL NLYLIMEFLP GGDMMTLLMK 180

KDTLTEEETQ FYIAETVLAI DSIHQLGFIH RDIKPDNLLL DSKGHVKLSD FGLCTGLKKA 240

HRTEFYRNLN HSLPSDFTFQ NMNSKRKAET WKRNRRQLAF STVGTPDYIA PEVFMQTGYN 300

KLCDWWSLGV IMYEMLIGYP PFCSETPQET YKKVMNWKET LTFPPEVPIS EKAKDLILRF 360

CCEWEHRIGA PGVEEIKSNP FFEGVDWEHI RERPAAISIE IRSIDDTSNF DEFPESDILK 420

PTVATSNHPE TDYKNKDWVF INYTYKRFEG LTARGAIPSY MKAGK 465

Nucleotide Sequence
(FASTA)

ATGGCAATGA CAGGCTCAAC ACCTTGTTCA TCCATGAGTA ATCATACAAA GGAACGTGTT 60

ACTATGACAA AAGTGACTTT GGAGAATTTT TACAGCAACC TTATTGCACA ACATGAGGAA 120

CGGGAGATGA GACAAAAGAA GCTAGAGAAA GTGATGGAAG AAGAAGGTTT AAAAGATGAA 180

GAGAAGCGAC TCAGGAGATC AGCACATGCT CGGAAGGAAA CAGAGTTTCT TCGATTAAAA 240

AGAACAAGAC TTGGACTGGA AGACTTCGAG TCCTTGAAAG TAATAGGCAG AGGAGCATTT 300

GGTGAGGTGA GACTTGTTCA GAAGAAAGAT ACAGGCCATG TATATGCAAT GAAAATACTT 360

CGCAAAGCGG ATATGCTTGA AAAAGAGCAG GTTGGCCACA TTCGTGCGGA GCGTGACATT 420

CTAGTGGAGG CAGACAGTTT GTGGGTTGTG AAAATGTTCT ATAGTTTTCA GGATAAGCTA 480

AACCTCTACC TAATCATGGA GTTCCTGCCT GGAGGTGACA TGATGACCTT ATTGATGAAA 540

AAAGATACTC TGACTGAAGA AGAGACTCAG TTCTACATAG CAGAAACAGT TTTGGCAATA 600

GACTCAATTC ATCAACTTGG ATTTATTCAT AGAGACATCA AACCAGATAA CCTCCTTTTG 660

GATAGCAAGG GTCATGTGAA GCTTTCTGAC TTTGGCCTCT GCACAGGACT AAAGAAAGCT 720

CATAGGACAG AATTTTATAG GAACTTGAAT CACAGTCTTC CCAGTGACTT CACTTTCCAG 780

AATATGAATT CCAAAAGGAA AGCAGAAACT TGGAAAAGAA ATAGACGTCA GCTAGCTTTC 840

TCCACAGTGG GTACTCCAGA TTACATTGCT CCTGAGGTGT TTATGCAAAC TGGATACAAT 900

AAGCTCTGTG ATTGGTGGTC TCTTGGGGTT ATCATGTATG AAATGCTCAT TGGTTACCCT 960

CCTTTTTGTT CTGAGACTCC TCAAGAAACT TATAAGAAGG TGATGAATTG GAAAGAAACA 1020

CTGACTTTTC CTCCAGAAGT TCCAATCTCT GAGAAAGCCA AGGATCTTAT TTTAAGATTC 1080

TGTTGCGAAT GGGAACATAG AATTGGAGCA CCTGGAGTTG AAGAAATTAA GAGTAATCCC 1140

TTTTTTGAAG GAGTTGACTG GGAACATATC AGGGAGAGGC CTGCTGCAAT ATCAATTGAG 1200

ATAAGGAGCA TTGATGACAC CTCAAACTTC GATGAATTTC CCGAATCTGA TATTCTTAAG 1260

CCAACAGTGG CAACAAGTAA CCATCCAGAA ACAGACTACA AGAACAAAGA TTGGGTCTTC 1320

ATCAATTACA CTTACAAACG TTTTGAGGGC CTGACAGCAC GAGGAGCAAT ACCTTCCTAT 1380

ATGAAAGCAG GAAAATAG 1398

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt++vya+kilrk+d+l+k+qv h++aerdil+eads w

Q: 89    FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLW  148

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk nlyl+me+lPGGd+mtll+kk++l+ee+++fyiae+vla++s+h+lGf

Q: 149   VVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGF  208

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+d+kGh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+ ++    ++++

Q: 209   IHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQ----NMNS  264

         *************************************************555....5555

S: 181   rkk....kknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPfla  236

         ++k    k+nrr+la+s+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++

Q: 265   KRKaetwKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCS  324

         5544556*****************************************************

S: 237   etpqetykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         etpqetykkv+nwketl+fp+ev++se+akdli r+++++e+r+g+ Gv+eik++pff

Q: 325   ETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGAPGVEEIKSNPFF  382

         *********************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHVYAMK ILRKADMLEK EQVGHIRAER DILVEADSLW 60

VVKMFYSFQD KLNLYLIMEF LPGGDMMTLL MKKDTLTEEE TQFYIAETVL AIDSIHQLGF 120

IHRDIKPDNL LLDSKGHVKL SDFGLCTGLK KAHRTEFYRN LNHSLPSDFT FQNMNSKRKA 180

ETWKRNRRQL AFSTVGTPDY IAPEVFMQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYKKVMNWK ETLTFPPEVP ISEKAKDLIL RFCCEWEHRI GAPGVEEIKS NPFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013