EKS-SAH-00088

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00088

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	397.0	7.5E-119	2696	3026	331

Status

Unreviewed

Ensembl Protein

ENSSHAP00000012661

UniProt Accession

G3WB56;

Protein Name

Protein Synonyms/Alias

Gene Name

ATM

Gene Synonyms/Alias

ATM;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000010836	ENSSHAP00000012661	ENSSHAT00000012765

Organism

Sarcophilus harrisii

Functional Description

Protein Length

3068

Protein Sequence
(FASTA)

MSLDLHDLLL CCRQLENDRA TERRKEVEKF KHLIRDPETV KHLDRNSDSR QGKYLNWDAV 60

FRFLQKYIQK ETECLRTAKP NVSASTQASR QKKMQEITSL VKYFIKCANK RAPRLKCQEL 120

LNYVMDTVKD SSSGTTYGAD YSNILLKDIL SVRKYWCEIS QHHWSELLAL YCTLYLKQSK 180

DINRVLVARI IQTVTRGCCS QTDGINLKFF DFFSKAMQCA RQEKSSAGLN HILAALNIFL 240

KVFAVNYRIR VCKLGEEILP TVLYIWSQQR PNDSLKDVII ELFHLQVRFH HPKGAKTQEK 300

GAYESAKWQS ILYNLYDLLL NEISHIGSRG KYSSGCRNIA VKENLVELMA DVCHQVFSED 360

TRVLEISQSY VTSPRDICSG STPSKRRKIE LGWEVIKDYL QKSHNDFDLV PWLQITTQLI 420

AKYPESLPNS ELTPLLTILH QLLSQQRRGE RIPYVLRCLV KLALCQGKKL DLETSHKSDL 480

LKLWNKIWSI TFRSISSEQI QAENFGLLGA IIEGNLVGVD RELWKIFTGS ACRPSCPAVC 540

CLSLALMSCI VPEMSKVGMD QSVCEINQGY SLKELIMKWL LFYQLEDDIE ESTELPPVLC 600

SDFPHLTLES ILVSLTMKNC KGAMDFFQSV TESEQQQKGK VEATFLEVEE LYLQTTFDQM 660

DFCTNMMYSA SEKIQTSAGL SFHQNLKETL DRYLLGLSEQ LLNNYSLETV RSEALVRCSS 720

LLVGVLGCYC HAGILSEEDA YKSKLFQNAK SLMQYAGKSI TLFKSKINEE SRICSLRTMM 780

LLCTNYLYNC TKNKLNKIIS GLFLRLLTSK LMNDIVDICT NLASLTKRPF DSGEVELMED 840

DVDVKLMEVE DQSTMNLFES DDTNINNANE SGEVQNTFGS ISPLAEEHLT KQDLLLLDML 900

KFLCICVTTA QSHTVSFRAC DIRRELLKLI EPSILDTSKS LHLHMYLVLL KELPVEEYPL 960

PMEEVSELLK PLSHVCSLYR RDQDVCRAIL SHILPIITNL GQHSSDVENT RNAQGQFLTV 1020

IGAFWHLTKE GKCVASVRMA LVNCLKALLE TDPYSKWAVL SIMEKDLPVT EVLPQFLADN 1080

HHQVRMLAAK SINRKKKRLF QETKQVAISR SSRAFPLKLQ QKAFENAYLK VQEGMKEMPL 1140

KSRSPVTAGE LLDEPYNRKA TLLMTVSMIL YCSPVCEKQA LFAICQSVKE NGLETQLVKK 1200

VLKRVSEIFD YKHLEDFMNS HLDYLVLEWL KLQNIGYNLS SFPFILLNYT NITDFYSSCY 1260

KALIPLLVMR GQFEDVKSIA DQIQKDWKNL LTDCFPKILV NILPYFAFES TGNNDMSERR 1320

DTATKVYDML KDENILGKQI DHLLNSNLAE IIVELLMTLH EPADTETSES TDLSPFSGDL 1380

DPAPNPPYFP SHVIKATLAY ISNCHKTKFK SIVDILSKSP DSFQKILLAI CEQAAETNNV 1440

YKKNRILKVY HLFVNLLLRE IKSGLGGAWA FVLRDIIYTL IHYINNSVRP SHFMDVSLRS 1500

FSICCDLLSK VCRTAVTYCK DALESHLHVI VGTIIPLVGD QLEIQEQVLD LLKYLVIENK 1560

DNENLYHTIR LLDPFPDHEA FKDLRITQQK IKYSKGPFSL LEEIHHFLSV SICDSLPLTR 1620

LEGLKELRKQ LEQHKDQMKD LLKESQDNPQ DGIMVKLIVS LLQLSKMAIN HTGEKEVLEA 1680

IGNCLGEVGP IDFSTIAIQH GKDASYSKAI DLFEDKELQW TFIMLKYLNN ALVEDCVKVR 1740

SAAVACLKNI LATKTGHEFW EIYKKTTDPM LIYLQPFRTS RKKFLEVPRI DKENPLENLD 1800

DPNLWVPQEE NHDSWIKTLT CTLLKSGGIK SEILLLLKPL CEVKPSFCQY VLPYLIHDIL 1860

LHDTNESWRN LLSVHIQGFF TNCFRHSSQS NRSTTPANLD SESEFLFRGS LNKKSRRTML 1920

AVVDYMRRQR RPFSGTVFDD TFWLELNYLE VAMVAQSCAA HFTALLYAEI YADRKNSDDQ 1980

QKRSLTFEDG SQCTTISSLS EKSKEETGIS LQDLLMKIYR SIGEPDSLYG CGGGKMLQPL 2040

IRIRTYEHEA MWGKALVTYD LETTLSPTTR QAGIIEALQN FGLCHTLSTY LKGLDYEHSE 2100

WCAEQQELCY QAAWRNMQWE YCPSHRKRTE GPGYHESLYN ALQSLRDKEF STFYGTLKYA 2160

RLKEVEELCK GSLESVYSLY PALSRLQAIG ELENIGKLFS RSITDRELTE VYGKWQRQSQ 2220

LLKDSDFGFQ EPIMALRTVI LETLMKKETE DSQREGIKNI LIKHLVELSV LARTARNTQL 2280

PERAMFQIKQ YTSARCGISE WQLEEAQVFW AKKEQSLALS ILKQMIKKLD ENFSQNDSSL 2340

KLIYAECLRV CGNWLAETCL ENPTVIMQTY LEKAVEIAGS FDGECSDKLR SGKMKAFLSL 2400

ARFSDIQYQR IENYMKSSEF ENKQALLNKA KQEVGLLREH KVQTNRYTVK VQRELELDEC 2460

AIRALREDRK RFLCKAVENY ISCLLSGEEH DMWIFRLCSL WLENSAVSGV NSMMKKDGVK 2520

IPSYKFLPLM YQLAARMGTK MMGGLGFHEV LNNLIARISR DHPHHTLFII LALANANKDE 2580

LLTKSEAATR SRITKNAPKQ ISQLDEDRME AANNIISIIK DGKAKMVRNV KELCDAYITL 2640

ANMDANPWKT QRKGINIPAD QPIIRLKNLD DVVVPTMEIK IDPTGEYENV VTIRSFKQEF 2700

RLAGGLNLPK IIDCVGSDGK ERRQLVKKGR DDLRQDAVMQ QVFQMCNMLL QKNTDTRKRK 2760

LTICTYKVVP LSQRSGVLEW CTGTVPIGEF LVNNEDGAHK RYRPKDFSAY QCQKKMMDMQ 2820

KKSFEEKYEA FINVCQNFQP VFRYFCMEKF LDPAVWFEKR LAYTRSVATS SIVGYILGLG 2880

DRHVQNILIN EQSAELVHID LGVAFEQGKI LPTPETVPFR LTRDIVDGMG ITGVEGVFRR 2940

CCEKTMEVMR NSQETLLTIV EVLLYDPLFD WTMNPLKALY LQQRPEDETE LNSTLNTEDQ 3000

EYNRNLGSRI DQSFNKVAER VLMRLQEKLK GVEEGTVLSV DGQVNLLIQQ AMDPKNLSRL 3060

FPGWKAWV 3068

Nucleotide Sequence
(FASTA)

ATGAGCCTCG ATTTACATGA TTTACTACTT TGCTGTCGTC AACTTGAAAA TGACAGAGCT 60

ACAGAACGAA GGAAAGAAGT TGAGAAATTC AAACATTTGA TCCGAGATCC TGAAACAGTT 120

AAACATTTGG ATCGGAATTC TGATTCTAGA CAAGGAAAAT ACTTGAACTG GGATGCTGTT 180

TTTAGGTTTC TGCAAAAATA CATCCAGAAG GAAACAGAAT GTTTGCGAAC AGCAAAACCA 240

AATGTATCGG CTTCAACACA AGCTTCCAGA CAGAAAAAGA TGCAAGAAAT TACCAGCTTG 300

GTTAAATACT TCATCAAATG TGCAAATAAA AGAGCCCCCA GATTGAAATG TCAAGAGCTT 360

CTAAATTATG TCATGGACAC AGTGAAGGAT TCCTCCAGTG GAACAACTTA TGGAGCTGAC 420

TATAGTAATA TATTGCTTAA GGACATTCTT TCAGTAAGGA AATACTGGTG TGAAATATCT 480

CAGCATCATT GGTCAGAACT TCTGGCCCTG TACTGTACAT TGTATCTCAA GCAGTCTAAA 540

GACATTAATA GAGTTTTAGT GGCTAGAATA ATTCAAACTG TAACCAGAGG ATGCTGTTCC 600

CAGACAGATG GAATAAATTT AAAGTTTTTT GATTTTTTTT CAAAGGCCAT GCAGTGTGCA 660

AGGCAGGAAA AAAGCTCTGC AGGATTGAAT CACATTCTGG CTGCCCTTAA TATCTTTCTC 720

AAGGTCTTTG CTGTAAATTA TCGTATTCGA GTTTGTAAAT TAGGAGAAGA AATCCTTCCT 780

ACTGTGCTTT ACATATGGTC TCAACAAAGA CCAAATGATT CTTTGAAGGA TGTAATTATT 840

GAATTATTTC ATCTGCAAGT TCGTTTTCAT CATCCAAAAG GAGCCAAAAC CCAAGAAAAA 900

GGAGCTTATG AATCAGCAAA ATGGCAAAGT ATTTTATACA ACTTATATGA TCTACTATTG 960

AATGAGATAA GTCATATCGG AAGCAGAGGA AAATATTCTT CTGGATGTCG AAACATTGCT 1020

GTCAAGGAAA ACTTGGTTGA ATTAATGGCA GATGTTTGTC ACCAGGTCTT CAGTGAAGAT 1080

ACCAGAGTCC TAGAAATCTC TCAGTCTTAT GTGACATCAC CAAGAGATAT TTGTAGTGGC 1140

AGTACACCTA GCAAAAGGAG AAAAATAGAA TTAGGTTGGG AAGTTATTAA AGATTATCTT 1200

CAAAAATCAC ATAATGATTT TGATCTTGTG CCATGGTTAC AGATTACAAC ACAGTTAATA 1260

GCAAAGTATC CTGAAAGTCT TCCTAACAGT GAACTTACAC CATTATTGAC AATACTTCAC 1320

CAGCTTCTAT CCCAGCAGCG ACGAGGGGAA CGTATTCCAT ATGTGTTAAG ATGCCTTGTC 1380

AAACTTGCAT TGTGTCAAGG AAAGAAACTG GATCTGGAAA CCTCCCATAA GTCAGATCTC 1440

CTGAAACTTT GGAATAAAAT TTGGTCTATT ACCTTTCGTA GTATAAGTTC TGAACAAATA 1500

CAGGCTGAAA ACTTTGGCTT ACTTGGCGCC ATAATTGAAG GAAATTTGGT TGGGGTTGAC 1560

AGAGAACTAT GGAAGATATT TACAGGATCA GCTTGTAGAC CTTCTTGTCC TGCAGTATGT 1620

TGTTTGTCAT TAGCCTTGAT GTCCTGCATA GTTCCAGAGA TGTCAAAAGT AGGAATGGAT 1680

CAGAGTGTTT GTGAAATAAA TCAAGGTTAC TCATTAAAAG AGTTAATTAT GAAGTGGCTG 1740

CTATTCTATC AGTTAGAAGA TGACATAGAA GAAAGTACAG AGCTCCCTCC AGTTCTTTGC 1800

AGTGATTTTC CTCATCTAAC TCTGGAGTCA ATTCTTGTGA GTCTCACCAT GAAAAACTGT 1860

AAAGGGGCAA TGGATTTTTT CCAGAGTGTG ACTGAAAGTG AGCAGCAGCA AAAAGGCAAA 1920

GTAGAAGCCA CATTCTTAGA AGTAGAAGAG CTATACCTTC AGACAACTTT TGACCAGATG 1980

GATTTTTGTA CCAATATGAT GTACAGTGCC TCTGAAAAAA TCCAGACTAG TGCTGGACTT 2040

TCTTTCCATC AGAATCTAAA AGAAACACTA GATCGCTATC TTCTGGGATT ATCTGAACAG 2100

CTTTTAAATA ATTATTCCCT TGAGACTGTG AGATCAGAAG CTCTTGTCCG ATGTTCCAGT 2160

CTTTTGGTGG GTGTTCTTGG TTGCTATTGT CATGCAGGTA TATTATCTGA AGAAGATGCA 2220

TATAAATCAA AATTGTTCCA GAATGCCAAG TCTCTGATGC AGTATGCTGG CAAAAGTATT 2280

ACATTGTTTA AAAGTAAGAT AAATGAAGAA TCTAGAATTT GTTCATTGAG GACTATGATG 2340

TTGCTTTGTA CCAACTATTT ATATAATTGT ACAAAGAACA AGCTGAATAA GATTATATCT 2400

GGCCTTTTTC TGCGTTTGTT AACATCAAAG TTGATGAATG ACATTGTGGA CATTTGCACA 2460

AATTTAGCAT CCCTTACTAA AAGACCATTT GATTCTGGAG AAGTGGAATT AATGGAAGAT 2520

GATGTTGATG TAAAGCTAAT GGAGGTAGAG GATCAATCAA CCATGAACCT ATTTGAATCT 2580

GATGACACTA ATATTAATAA TGCAAATGAA TCTGGAGAGG TACAAAATAC TTTTGGTTCA 2640

ATAAGTCCTC TAGCTGAAGA ACATTTAACA AAGCAAGATC TTCTTCTCCT GGACATGCTA 2700

AAGTTCTTAT GTATATGTGT AACTACTGCT CAGTCCCATA CAGTATCTTT TAGAGCATGT 2760

GACATAAGGA GGGAGCTGTT GAAGCTAATT GAACCCAGCA TACTAGACAC TTCTAAATCC 2820

CTCCACCTAC ACATGTACTT GGTGCTTTTA AAGGAACTCC CAGTTGAAGA ATATCCCTTG 2880

CCGATGGAAG AAGTTTCTGA ACTTCTGAAG CCTCTTTCGC ATGTGTGTTC TTTGTATCGT 2940

CGTGACCAAG ATGTTTGCAG AGCAATCTTA AGCCACATTT TGCCAATAAT AACAAATCTG 3000

GGTCAACATA GTTCAGATGT AGAAAATACA AGAAATGCAC AAGGACAATT TCTAACAGTC 3060

ATAGGAGCTT TTTGGCATTT AACAAAGGAA GGCAAATGTG TGGCATCTGT GAGAATGGCA 3120

CTAGTAAACT GCCTGAAAGC CTTGCTTGAG ACTGATCCTT ATTCGAAGTG GGCTGTTCTT 3180

AGCATAATGG AAAAAGACTT ACCTGTGACT GAGGTTCTTC CACAGTTTCT TGCTGACAAC 3240

CATCATCAAG TTCGAATGCT TGCTGCAAAG TCAATTAACC GAAAAAAAAA AAGATTATTT 3300

CAGGAAACAA AACAAGTAGC CATTTCAAGG TCATCAAGAG CATTTCCTTT GAAGCTCCAG 3360

CAAAAAGCTT TTGAAAATGC ATATTTAAAA GTTCAGGAAG GAATGAAAGA AATGCCATTG 3420

AAGTCTCGAA GTCCTGTTAC TGCTGGTGAA CTTCTAGATG AGCCTTATAA TAGAAAAGCT 3480

ACTTTATTGA TGACAGTATC CATGATTTTA TACTGTAGCC CTGTATGTGA AAAACAGGCT 3540

TTATTTGCCA TATGCCAGTC AGTGAAAGAA AATGGATTAG AAACCCAACT TGTAAAAAAG 3600

GTTTTGAAGA GAGTCTCTGA AATTTTCGAC TATAAACACT TAGAAGACTT CATGAATTCT 3660

CATCTAGACT ATCTGGTTTT GGAGTGGTTG AAATTACAAA ATATTGGATA TAACTTGTCA 3720

TCTTTTCCTT TTATTTTACT GAACTACACA AACATTACAG ATTTCTACAG TTCTTGCTAT 3780

AAGGCTTTAA TTCCACTTTT GGTGATGAGA GGTCAGTTTG AAGATGTGAA GTCCATTGCT 3840

GACCAGATCC AGAAGGATTG GAAAAACCTT CTAACAGATT GTTTTCCTAA GATCCTTGTA 3900

AACATTCTTC CATATTTTGC CTTTGAGAGC ACGGGGAACA ATGATATGTC AGAGCGAAGA 3960

GACACTGCTA CTAAAGTATA TGATATGCTT AAGGATGAAA ATATTTTAGG GAAACAGATT 4020

GATCATTTAC TTAACAGTAA TTTGGCAGAG ATCATAGTGG AACTATTGAT GACATTACAT 4080

GAGCCAGCAG ATACTGAAAC TAGTGAAAGC ACTGACCTCT CTCCCTTTTC AGGGGACCTT 4140

GATCCTGCCC CTAATCCTCC ATACTTTCCA TCACATGTGA TCAAAGCAAC GTTGGCTTAT 4200

ATCAGCAATT GCCATAAAAC AAAGTTTAAA AGTATTGTAG ACATTCTTTC TAAGAGCCCA 4260

GATTCCTTCC AGAAAATCCT TTTAGCCATA TGTGAACAAG CAGCTGAAAC AAATAATGTA 4320

TATAAAAAAA ATAGAATTCT TAAAGTATAT CATCTCTTTG TTAATCTATT ACTGAGAGAA 4380

ATAAAAAGTG GCTTGGGTGG AGCTTGGGCT TTTGTTCTTC GAGATATTAT TTATACCTTA 4440

ATCCACTATA TCAATAATAG TGTTAGGCCT TCCCATTTCA TGGATGTATC ATTGCGCAGC 4500

TTTTCAATCT GCTGTGACCT GTTAAGTAAG GTTTGCCGGA CAGCAGTGAC TTACTGTAAG 4560

GATGCTTTGG AAAGCCATCT TCATGTTATT GTGGGCACAA TCATACCTTT GGTGGGTGAC 4620

CAGTTGGAGA TTCAGGAACA GGTCTTAGAC CTGTTGAAAT ATCTAGTGAT AGAAAACAAA 4680

GACAATGAAA ACCTTTATCA CACAATTAGA CTCCTAGACC CATTTCCTGA TCATGAAGCC 4740

TTTAAGGACT TACGTATCAC TCAGCAGAAA ATCAAATACA GTAAAGGACC CTTTTCGCTC 4800

TTGGAGGAAA TTCATCATTT CCTTTCGGTA AGTATCTGTG ATTCACTACC TTTGACCAGA 4860

CTTGAAGGAT TAAAGGAGCT TCGAAAGCAA CTGGAACAAC ATAAAGATCA AATGAAAGAC 4920

CTTTTGAAAG AATCTCAAGA TAACCCACAA GATGGCATTA TGGTGAAGCT TATTGTGAGT 4980

TTACTGCAAC TATCTAAGAT GGCAATAAAC CATACTGGTG AAAAGGAAGT TTTAGAGGCC 5040

ATTGGAAACT GCTTGGGAGA AGTGGGTCCT ATAGATTTTT CTACCATAGC CATTCAGCAT 5100

GGTAAAGATG CATCTTATTC TAAGGCCATT GACTTATTTG AGGATAAAGA ACTTCAGTGG 5160

ACCTTCATAA TGCTCAAATA CTTAAATAAT GCACTGGTTG AAGATTGTGT TAAGGTTCGA 5220

TCAGCTGCTG TTGCATGTTT GAAAAATATT TTAGCCACAA AGACTGGACA TGAGTTCTGG 5280

GAGATTTATA AGAAAACAAC TGATCCCATG CTTATATACC TACAACCTTT TAGAACATCT 5340

AGGAAAAAGT TTCTAGAAGT TCCTAGAATT GACAAAGAAA ATCCTTTGGA AAACTTGGAT 5400

GATCCAAATT TGTGGGTTCC ACAGGAAGAA AATCATGATA GTTGGATCAA GACATTGACT 5460

TGTACACTTT TGAAGAGTGG GGGCATAAAA AGTGAAATTC TTTTGTTATT GAAGCCACTG 5520

TGTGAAGTGA AACCCAGCTT TTGTCAGTAT GTGCTTCCAT ATTTGATTCA TGATATTTTG 5580

CTCCATGATA CAAATGAGTC CTGGCGAAAT CTTTTATCTG TGCATATCCA GGGATTTTTT 5640

ACGAACTGTT TCAGACATTC CTCACAATCC AACCGATCTA CAACTCCTGC AAATTTAGAT 5700

TCAGAATCAG AATTTCTTTT TCGAGGATCT TTAAATAAAA AATCAAGACG AACAATGCTT 5760

GCTGTTGTGG ATTATATGAG AAGACAGAGA AGACCCTTCT CAGGGACAGT TTTTGATGAC 5820

ACTTTCTGGC TGGAGTTGAA TTATTTGGAG GTTGCCATGG TAGCTCAGTC TTGTGCAGCT 5880

CACTTCACAG CATTACTGTA TGCAGAAATC TATGCAGACA GGAAAAACTC GGATGATCAA 5940

CAGAAAAGAA GTTTAACATT TGAAGATGGA AGTCAGTGTA CAACTATTTC TAGTTTGAGT 6000

GAGAAAAGTA AAGAAGAAAC TGGAATAAGT TTACAGGATC TTCTTATGAA AATTTATAGA 6060

AGTATTGGAG AACCTGACAG TCTTTATGGC TGTGGTGGAG GGAAAATGTT ACAGCCCCTT 6120

ATCAGGATAA GAACATATGA ACATGAAGCA ATGTGGGGGA AAGCACTTGT GACCTATGAC 6180

CTTGAGACAA CTCTCTCCCC AACTACACGC CAGGCAGGAA TAATAGAGGC CTTGCAGAAT 6240

TTTGGTCTCT GCCACACTCT TTCTACTTAC TTAAAAGGAC TAGATTATGA ACATTCAGAG 6300

TGGTGTGCTG AGCAGCAGGA ACTTTGCTAC CAAGCAGCAT GGAGGAACAT GCAATGGGAA 6360

TATTGTCCTT CTCACAGAAA AAGAACAGAA GGACCTGGTT ATCATGAATC ATTGTACAAT 6420

GCCCTGCAGT CTTTAAGAGA CAAAGAATTC TCTACATTCT ATGGAACCCT TAAATATGCC 6480

AGACTGAAAG AGGTGGAAGA ATTGTGTAAA GGCAGCCTTG AGTCTGTATA CTCACTCTAC 6540

CCTGCTCTCA GCAGATTACA GGCTATTGGA GAGTTAGAAA ATATAGGAAA ACTTTTTTCC 6600

AGATCCATCA CTGATAGAGA ACTCACTGAG GTATATGGGA AGTGGCAGAG ACAGTCTCAG 6660

CTTCTCAAAG ATAGTGATTT TGGTTTTCAA GAGCCTATCA TGGCATTGCG TACAGTCATT 6720

CTAGAGACCC TAATGAAAAA AGAAACTGAG GATTCACAAA GGGAAGGTAT TAAGAATATT 6780

CTCATAAAGC ACCTTGTAGA ACTATCTGTT TTGGCCCGGA CTGCCAGAAA CACACAGCTT 6840

CCTGAAAGGG CAATGTTTCA AATCAAACAG TATACTTCAG CAAGATGTGG AATCTCTGAA 6900

TGGCAGCTGG AGGAAGCTCA AGTGTTCTGG GCTAAAAAGG AACAGAGTCT TGCCCTAAGT 6960

ATTCTAAAAC AAATGATCAA GAAGTTAGAT GAAAATTTTT CTCAGAATGA CTCAAGCCTG 7020

AAACTGATAT ATGCAGAATG TTTGAGAGTT TGTGGAAACT GGTTGGCAGA AACTTGCTTA 7080

GAAAACCCCA CAGTCATTAT GCAGACATAC CTAGAAAAGG CAGTGGAAAT TGCTGGCAGT 7140

TTTGATGGAG AGTGTAGTGA TAAACTGAGG AGTGGAAAGA TGAAGGCTTT CCTATCATTG 7200

GCACGTTTTT CAGATATTCA GTATCAAAGA ATTGAAAACT ATATGAAATC ATCAGAATTT 7260

GAAAATAAAC AAGCTCTGCT GAATAAGGCT AAACAGGAAG TGGGCCTTCT TAGGGAACAC 7320

AAAGTCCAGA CAAACAGATA TACAGTGAAG GTTCAGAGAG AGCTAGAGCT GGATGAATGT 7380

GCAATCCGTG CATTGAGAGA AGATCGCAAA CGCTTCTTGT GTAAAGCAGT TGAGAATTAT 7440

ATCAGCTGTT TGCTTAGTGG AGAAGAACAT GATATGTGGA TATTTCGACT TTGTTCTCTT 7500

TGGCTCGAAA ACTCTGCAGT TTCTGGAGTC AATAGCATGA TGAAGAAAGA TGGAGTGAAG 7560

ATTCCCTCAT ACAAGTTTCT GCCTCTTATG TACCAGCTGG CTGCTAGAAT GGGAACCAAA 7620

ATGATGGGAG GCCTAGGATT TCATGAAGTT CTGAATAATC TCATTGCTAG AATTTCACGG 7680

GATCACCCCC ATCATACTTT GTTTATTATA CTAGCCTTAG CAAATGCAAA TAAGGATGAA 7740

CTTCTAACCA AATCAGAAGC AGCAACAAGA AGCAGAATAA CGAAAAATGC ACCAAAGCAA 7800

ATTTCTCAGC TTGATGAGGA TCGAATGGAA GCTGCAAACA ACATAATAAG TATTATCAAA 7860

GATGGAAAAG CCAAGATGGT CAGAAATGTG AAAGAACTTT GTGATGCTTA TATCACATTA 7920

GCCAATATGG ATGCCAACCC ATGGAAGACT CAGAGAAAAG GTATAAACAT TCCTGCAGAC 7980

CAGCCCATTA TTAGACTAAA GAACTTAGAC GACGTTGTTG TTCCCACCAT GGAAATTAAG 8040

ATTGACCCTA CAGGAGAATA TGAAAATGTG GTGACTATAC GGTCATTCAA GCAAGAATTT 8100

CGTTTAGCAG GAGGTCTGAA TCTACCTAAA ATAATAGATT GTGTAGGATC AGATGGTAAA 8160

GAGAGGAGAC AGCTTGTCAA GAAGGGTCGA GATGACCTGC GTCAAGATGC AGTGATGCAG 8220

CAAGTTTTCC AGATGTGTAA TATGTTACTC CAGAAAAACA CTGACACAAG AAAGAGAAAA 8280

TTAACAATTT GCACATATAA GGTGGTTCCC CTTTCTCAGC GAAGTGGTGT CCTTGAATGG 8340

TGTACGGGGA CAGTGCCCAT TGGTGAATTT CTTGTTAATA ATGAAGATGG AGCTCATAAA 8400

AGATACAGGC CAAAGGACTT TAGTGCTTAT CAGTGCCAAA AGAAAATGAT GGATATGCAG 8460

AAGAAATCTT TTGAAGAAAA GTATGAAGCT TTCATAAATG TTTGCCAAAA CTTTCAGCCA 8520

GTCTTCCGTT ACTTTTGCAT GGAAAAATTC TTGGACCCTG CAGTTTGGTT TGAAAAGCGA 8580

TTGGCATATA CTCGCAGTGT GGCTACTTCT TCTATTGTTG GTTACATACT TGGACTTGGT 8640

GATCGACATG TCCAGAATAT CTTGATCAAT GAGCAATCAG CAGAGCTTGT GCACATAGAT 8700

TTAGGGGTTG CATTTGAACA AGGAAAGATT CTTCCTACCC CTGAAACAGT TCCTTTTAGA 8760

CTCACCAGAG ATATTGTAGA TGGAATGGGT ATCACTGGTG TGGAAGGTGT CTTCAGAAGG 8820

TGCTGTGAGA AAACCATGGA AGTTATGAGA AATTCTCAGG AAACTCTTTT AACCATTGTC 8880

GAGGTCTTGC TCTATGATCC TCTTTTTGAT TGGACCATGA ACCCCTTGAA AGCTTTGTAT 8940

TTACAACAGA GACCAGAGGA TGAGACTGAA CTCAATTCTA CTCTAAATAC AGAAGATCAA 9000

GAGTATAACA GAAATCTTGG CAGTCGTATT GACCAGAGTT TCAACAAAGT GGCTGAACGT 9060

GTTCTAATGA GGCTACAGGA AAAGCTGAAA GGAGTAGAGG AAGGAACAGT GCTCAGCGTG 9120

GATGGACAAG TGAATTTGCT CATCCAACAA GCAATGGATC CCAAAAATCT CAGCCGACTA 9180

TTTCCTGGAT GGAAAGCTTG GGTATAA 9207

Domain Profile

S: 4     fderveilaskqkpkklllrGsdgkeypyLv.kgkeDlrqdervlqlfslvNtlLakdke  62

         f+++  +   ++ pk +   Gsdgke+++Lv kg++Dlrqd++++q+f+++N lL+k++

Q: 2696  FKQEFRLAGGLNLPKIIDCVGSDGKERRQLVkKGRDDLRQDAVMQQVFQMCNMLLQKNTD  2755

         555555556667899999*************99***************************

S: 63    tsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdlst  122

         t++rkL+i+tykVvpls+rsg++ew+++tv+++e+l   v++++++++   +yr+kd+s+

Q: 2756  TRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFL---VNNEDGAHK---RYRPKDFSA  2809

         ************************************...799*****9...*********

S: 123   vqarkpklkhlkls....levfkevlenlvpkdllkklllekfpspeewfelrkaytrsl  178

          q++k++++ +k+s    +e f +v++n++p  +++++++ekf++p++wfe+r aytrs+

Q: 2810  YQCQKKMMDMQKKSfeekYEAFINVCQNFQP--VFRYFCMEKFLDPAVWFEKRLAYTRSV  2867

         *******************************..9**************************

S: 179   AvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrniv  238

         A++s+vgyiLgLgdrh++n+li+++++e+vhid+gvafe++k+ l++pe+vPFRLTr+iv

Q: 2868  ATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKI-LPTPETVPFRLTRDIV  2926

         *******************************************.****************

S: 239   nalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk......kkktske  292

         +++g+tgveGvfr++ce++++v+r+s+e+llti+ev+lydpl+dw++      + ++++e

Q: 2927  DGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMnplkalYLQQRPE  2986

         *****************************************************9******

S: 293   teeelaekakaealkikkll.skvekaenavatrdlllle  331

         +e+el+++ ++e+++ +++l s +++++n+va+r+l++l+

Q: 2987  DETELNSTLNTEDQEYNRNLgSRIDQSFNKVAERVLMRLQ  3026

         ***************99988578************99987

Domain Sequence
(FASTA)

FKQEFRLAGG LNLPKIIDCV GSDGKERRQL VKKGRDDLRQ DAVMQQVFQM CNMLLQKNTD 60

TRKRKLTICT YKVVPLSQRS GVLEWCTGTV PIGEFLVNNE DGAHKRYRPK DFSAYQCQKK 120

MMDMQKKSFE EKYEAFINVC QNFQPVFRYF CMEKFLDPAV WFEKRLAYTR SVATSSIVGY 180

ILGLGDRHVQ NILINEQSAE LVHIDLGVAF EQGKILPTPE TVPFRLTRDI VDGMGITGVE 240

GVFRRCCEKT MEVMRNSQET LLTIVEVLLY DPLFDWTMNP LKALYLQQRP EDETELNSTL 300

NTEDQEYNRN LGSRIDQSFN KVAERVLMRL Q 331

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0000077	; P:DNA damage checkpoint
GO:0006281	; P:DNA repair
GO:0016572	; P:histone phosphorylation
GO:0090399	; P:replicative senescence
GO:0010212	; P:response to ionizing radiation
GO:0000723	; P:telomere maintenance

KEGG

InterPros

IPR016024	; ARM-type_fold.
IPR015519	; ATM/Tel1.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR021668	; TAN.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF11640	; TAN; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013