EKS-SAH-00259

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00259

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	452.4	6.7E-136	88	375	288

Status

Unreviewed

Ensembl Protein

ENSSHAP00000012727

UniProt Accession

G3WBC1;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1B

Gene Synonyms/Alias

BMPR1B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000010891	ENSSHAP00000012727	ENSSHAT00000012831
ENSSHAG00000010891	ENSSHAP00000012726	ENSSHAT00000012830

Organism

Sarcophilus harrisii

Functional Description

Protein Length

386

Protein Sequence
(FASTA)

EFVDGSIHHK AILISVTVCS FLLILIILFC YFRYKRQEAR PRYSIGLEQD ETYIPPGESL 60

KDLIEQSQSS GSGSGLPLLV QRTIAKQIQM VKQIGKGRYG EVWMGKWRGE KVAVKVFFTT 120

EEASWFRETE IYQTVLMRHE NILGFIAADI KGTGSWTQLY LITDYHENGS LYDYLKSTTL 180

DTKAMLKLAY SSVSGLCHLH TEIFSTQGKP AIAHRDLKSK NILVKKNGAC CIADLGLAVK 240

FISDTNEVDI PSNTRVGTKR YMPPEVLDET LNRNHFQSYI MADMYSFGLI LWEIARRCVS 300

GGIVEEYQLP YHDLVPSDPS YEDMREIVCI KKLRPSFPNR WSSDECLRQM GKLMTECWAH 360

NPASRLTALR VKKTLAKMSE SQDIKL 386

Nucleotide Sequence
(FASTA)

GAATTTGTGG ATGGATCCAT ACACCATAAG GCCATATTGA TATCTGTGAC AGTCTGTAGC 60

TTCCTTCTGA TACTAATAAT TCTATTCTGT TATTTCAGGT ATAAAAGGCA AGAAGCTAGA 120

CCTCGTTATA GCATCGGACT GGAACAAGAT GAGACTTACA TCCCTCCAGG GGAATCTTTA 180

AAAGATTTAA TCGAACAATC TCAGAGCTCA GGAAGTGGAT CAGGGCTCCC TCTGCTGGTC 240

CAAAGGACTA TAGCTAAGCA GATTCAGATG GTCAAACAGA TTGGAAAAGG TCGCTATGGG 300

GAAGTTTGGA TGGGAAAGTG GCGTGGTGAA AAGGTAGCTG TGAAAGTGTT CTTTACCACT 360

GAGGAAGCCA GCTGGTTCAG AGAGACGGAG ATATATCAGA CAGTCTTGAT GAGGCATGAA 420

AATATTTTGG GCTTTATTGC TGCAGATATC AAAGGCACTG GGTCGTGGAC CCAACTATAC 480

CTAATCACAG ACTACCATGA GAATGGTTCC TTGTATGATT ATCTGAAGTC TACTACCTTA 540

GATACCAAAG CAATGTTAAA GTTGGCCTAT TCTTCAGTCA GTGGCCTGTG CCACTTACAT 600

ACAGAGATCT TTAGTACTCA AGGGAAACCC GCAATTGCAC ATCGTGATCT CAAAAGTAAG 660

AATATCCTGG TGAAGAAAAA TGGAGCATGC TGTATAGCTG ATCTGGGATT GGCAGTTAAA 720

TTTATTAGTG ACACCAATGA AGTAGACATC CCATCCAACA CTCGAGTTGG CACCAAACGT 780

TATATGCCAC CGGAGGTGCT AGATGAGACT TTGAATCGGA ACCACTTCCA GTCCTACATC 840

ATGGCAGATA TGTACAGTTT TGGCCTTATT CTGTGGGAAA TTGCCCGGAG ATGTGTTTCT 900

GGTGGAATAG TAGAAGAATA CCAACTGCCT TACCATGATC TGGTACCTAG TGATCCCTCC 960

TATGAAGATA TGAGGGAGAT TGTATGCATC AAAAAACTCC GACCATCCTT TCCTAACAGG 1020

TGGAGTAGTG ACGAGTGTCT ACGGCAGATG GGGAAACTCA TGACAGAATG CTGGGCCCAC 1080

AATCCTGCAT CCCGACTCAC AGCCCTTCGG GTTAAGAAAA CACTTGCCAA AATGTCAGAG 1140

TCACAGGACA TTAAACTCTG A 1161

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++++++igkGrygeVw++k+rge+vAvK+f+t++easw+rE+eiyqtvl+rhenil+fia

Q: 88    IQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIA  147

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++s+t+l+l+t+yhe+gsL+dyLk++tld++ +l+la+s +sGl+hLH+ei+ t+

Q: 148   ADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDTKAMLKLAYSSVSGLCHLHTEIFSTQ  207

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNilvkk+++cciaDlGLa+k+ ++++e+d+ +n++vGtkRYm PE

Q: 208   G--KPAIAHRDLKSKNILVKKNGACCIADLGLAVKFISDTNEVDIPSNTRVGTKRYMPPE  265

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln ++f+++ +aD+Ys+gL+lWE+a+Rc + +++veey+lp+++ v+sdPs+e+m

Q: 266   VLDETLNRNHFQSYIMADMYSFGLILWEIARRCVS-GGIVEEYQLPYHDLVPSDPSYEDM  324

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         +e+v+ kklrP++p++w+++e+l+++ kl++ecW+++p++Rltalrvkk+l

Q: 325   REIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTL  375

         *************************************************97

Domain Sequence
(FASTA)

IQMVKQIGKG RYGEVWMGKW RGEKVAVKVF FTTEEASWFR ETEIYQTVLM RHENILGFIA 60

ADIKGTGSWT QLYLITDYHE NGSLYDYLKS TTLDTKAMLK LAYSSVSGLC HLHTEIFSTQ 120

GKPAIAHRDL KSKNILVKKN GACCIADLGL AVKFISDTNE VDIPSNTRVG TKRYMPPEVL 180

DETLNRNHFQ SYIMADMYSF GLILWEIARR CVSGGIVEEY QLPYHDLVPS DPSYEDMREI 240

VCIKKLRPSF PNRWSSDECL RQMGKLMTEC WAHNPASRLT ALRVKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0004675	; F:transmembrane receptor protein serine/threonine kinase activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013