EKS-SAH-00246

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00246

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	348.2	3.0E-104	77	322	246

Status

Unreviewed

Ensembl Protein

ENSSHAP00000013278

UniProt Accession

G3WCX3;

Protein Name

Protein Synonyms/Alias

Gene Name

PLK3

Gene Synonyms/Alias

PLK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000011352	ENSSHAP00000013278	ENSSHAT00000013387

Organism

Sarcophilus harrisii

Functional Description

Protein Length

657

Protein Sequence
(FASTA)

PAPAPFQFSL HTLPRSSFLR LGPIGPVPSG SPRVKPQAPE DGAACKTKRP ESRARISWPG 60

SGRGHGAGRF LPPAAPGEGG FARCYEATDT SSGHTYAVKV IPQSRVAKPH QREKILQEIA 120

LHRSLHHRHI VRFSHHFEDE GSIYIFLEYC SRKSLAHIWK ARHILLEPEV RYYLRQVIAG 180

LRYLHQRGVL HRDLKLGNFF ITTRGCYLEP GDRLGLCSQL EMARAGTICG TPNYLAPEVL 240

LRQGHGPESD VWSLGCVMYT LLCGSPPFET TDLKETYRCI KQVRYTLPTY LSVCARHLLA 300

AILRPVPQDR PSLEEILQHD FFTKGYTPAQ LPPSSCTTVP DLTPPSPAQS FFTKVTKSLF 360

GRKKKSKLAV QEQDNLSRLV SDLVLMSICP QNSSKEPRQA QKEADVPPSL AETAPEEGSP 420

RSLAAMGSSC EGSEECLTAA AVMESTLCAL RNCLAFMPPA EQNPAPLASS EHLLWVSKWV 480

DYSNKYGFGY QLSSRQVAVL FNDGTHMALS SNRKNVHYNP TSTKHFCFPM EAVPQQLQRQ 540

LGVLRYFASY MDQNLMKGGD LPSMDETESP APLLLQWFKT DQALLLLFSD GTVQVNFYVD 600

HTKLILSGWE PLLITFVARD RRALTYQAPH LQRLGCSPEL RVRLRFVLGL LRQHSGT 657

Nucleotide Sequence
(FASTA)

CCGGCCCCAG CCCCCTTTCA GTTCAGTCTT CACACACTGC CCAGGTCGAG CTTCCTCAGG 60

CTTGGGCCAA TCGGGCCTGT TCCCTCGGGA AGCCCGAGAG TAAAACCACA GGCGCCCGAG 120

GACGGGGCCG CGTGCAAGAC CAAGAGGCCG GAGTCGCGTG CGCGGATCTC GTGGCCGGGC 180

TCAGGCCGCG GCCATGGAGC CGGCCGCTTT CTTCCGCCCG CAGCCCCTGG CGAGGGGGGC 240

TTCGCCCGAT GCTACGAGGC CACGGACACC AGCAGTGGCC ACACCTACGC TGTCAAGGTC 300

ATTCCCCAGA GCCGGGTGGC CAAACCACAC CAGCGGGAGA AGATCCTGCA GGAGATCGCC 360

CTGCACCGCA GCCTCCACCA CCGGCACATC GTTCGCTTTT CGCACCACTT TGAGGATGAA 420

GGCAGCATCT ACATATTTCT GGAGTACTGC AGCCGAAAGT CACTGGCACA CATCTGGAAG 480

GCGAGACACA TACTTCTGGA GCCCGAGGTC CGCTACTACC TTCGACAGGT TATTGCCGGT 540

TTGCGCTACC TGCACCAACG AGGAGTTTTA CACCGAGACC TCAAACTGGG AAATTTTTTC 600

ATCACGACAA GGGGGTGTTA TCTGGAACCT GGAGACAGGC TGGGCCTTTG TTCCCAGCTA 660

GAAATGGCTA GGGCGGGGAC CATCTGTGGG ACCCCCAATT ATCTGGCCCC TGAGGTGCTG 720

CTACGCCAGG GTCACGGCCC TGAGTCCGAC GTGTGGTCAC TGGGCTGTGT GATGTATACA 780

CTGCTGTGTG GGAGCCCCCC CTTTGAGACG ACTGACCTGA AGGAGACATA CCGTTGCATC 840

AAGCAGGTTC GCTACACGTT GCCCACCTAC CTCTCTGTGT GTGCCCGACA CCTCCTTGCC 900

GCCATCCTTC GCCCTGTGCC CCAAGACCGG CCCTCACTGG AGGAGATCCT TCAGCATGAC 960

TTCTTCACCA AGGGCTATAC TCCAGCTCAA CTTCCCCCAA GTAGCTGCAC CACAGTCCCT 1020

GACCTGACCC CCCCCAGCCC TGCCCAAAGC TTCTTCACTA AAGTGACCAA GAGCCTCTTT 1080

GGCCGCAAGA AGAAGAGTAA GCTGGCTGTC CAGGAACAGG ACAACCTCTC CCGCCTGGTC 1140

AGCGACCTCG TGTTGATGTC CATCTGCCCT CAGAACAGCT CCAAGGAGCC AAGGCAGGCC 1200

CAGAAGGAGG CTGATGTCCC CCCCAGTCTA GCAGAAACCG CCCCTGAGGA AGGTTCCCCC 1260

AGATCCTTGG CAGCCATGGG CAGCAGCTGT GAGGGGTCTG AGGAGTGTCT GACAGCAGCT 1320

GCTGTCATGG AATCTACCCT CTGTGCCCTT CGGAACTGCC TGGCCTTCAT GCCCCCAGCT 1380

GAACAAAACC CAGCACCCCT GGCCTCATCG GAACATCTGC TATGGGTCAG CAAATGGGTA 1440

GACTACTCCA ACAAGTACGG CTTTGGCTAC CAGCTGTCCA GCCGGCAGGT GGCCGTCCTC 1500

TTCAATGATG GCACCCACAT GGCCCTGTCG TCCAACAGGA AAAACGTGCA TTATAATCCA 1560

ACCAGCACCA AGCACTTCTG CTTCCCCATG GAGGCTGTTC CTCAGCAGCT GCAGCGCCAG 1620

CTGGGGGTCC TTCGCTATTT TGCCTCCTAC ATGGACCAGA ACCTTATGAA GGGTGGAGAC 1680

CTGCCCAGCA TGGATGAGAC TGAGAGCCCG GCACCCCTGC TCCTGCAGTG GTTCAAGACG 1740

GACCAGGCCC TGCTGCTCTT GTTCAGCGAC GGCACGGTGC AGGTGAATTT CTACGTGGAC 1800

CACACCAAGC TGATCCTCAG CGGCTGGGAG CCCCTGCTCA TCACCTTCGT GGCCCGGGAC 1860

CGCCGGGCCC TCACCTACCA AGCCCCTCAT CTGCAGCGGC TGGGCTGCAG CCCCGAGCTG 1920

CGCGTCCGGC TCCGATTCGT CCTGGGGCTG CTGCGGCAGC ACAGCGGGAC CTAG 1974

Domain Profile

S: 8     GkGgfakcyelkdletkevfavkvvpksllakekqrekvekeieihrslkhknivklyef  67

         G+Ggfa+cye++d+++++++avkv+p+s++ak++qrek+ +ei++hrsl+h++iv+++++

Q: 77    GEGGFARCYEATDTSSGHTYAVKVIPQSRVAKPHQREKILQEIALHRSLHHRHIVRFSHH  136

         9***********************************************************

S: 68    fedkenvylvlelcsrrslaellkrrkaltepevryylrqivsglkylhekrilhrdlkl  127

         fed+  +y++le+csr+sla+++k+r+ l epevryylrq+++gl+ylh++ +lhrdlkl

Q: 137   FEDEGSIYIFLEYCSRKSLAHIWKARHILLEPEVRYYLRQVIAGLRYLHQRGVLHRDLKL  196

         ************************************************************

S: 128   gnlflne.elevkigd.fGlatrlekeeerkktlcGtPnyiaPevlskkghslevdiWsl  185

         gn+f++     +  gd +Gl ++le    r  t+cGtPny+aPevl ++gh+ e+d+Wsl

Q: 197   GNFFITTrGCYLEPGDrLGLCSQLE--MARAGTICGTPNYLAPEVLLRQGHGPESDVWSL  254

         ****97516899***989******9..56899****************************

S: 186   GcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllkkePeerpsle  245

         Gc++ytll+G+PPfet++lkety++ik+ +y+lP+ ls  a++l+a++l++ P++rpsle

Q: 255   GCVMYTLLCGSPPFETTDLKETYRCIKQVRYTLPTYLSVCARHLLAAILRPVPQDRPSLE  314

         ************************************************************

S: 246   evlkdefl  253

         e+l+++f+

Q: 315   EILQHDFF  322

         *******8

Domain Sequence
(FASTA)

GEGGFARCYE ATDTSSGHTY AVKVIPQSRV AKPHQREKIL QEIALHRSLH HRHIVRFSHH 60

FEDEGSIYIF LEYCSRKSLA HIWKARHILL EPEVRYYLRQ VIAGLRYLHQ RGVLHRDLKL 120

GNFFITTRGC YLEPGDRLGL CSQLEMARAG TICGTPNYLA PEVLLRQGHG PESDVWSLGC 180

VMYTLLCGSP PFETTDLKET YRCIKQVRYT LPTYLSVCAR HLLAAILRPV PQDRPSLEEI 240

LQHDFF 246

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000959	; POLO_box_duplicated_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR020658	; Ser/Thr_kinase_Plk3.

Pfam

PF00069	; Pkinase; 1.
PF00659	; POLO_box; 2.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50078	; POLO_BOX; 2.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013