EKS-SAH-00145

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00145

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	521.8	5.1E-157	90	383	294

Status

Unreviewed

Ensembl Protein

ENSSHAP00000013756

UniProt Accession

G3WEA1;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38L

Gene Synonyms/Alias

STK38L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000011764	ENSSHAP00000013756	ENSSHAT00000013870

Organism

Sarcophilus harrisii

Functional Description

Protein Length

464

Protein Sequence
(FASTA)

MAMTAGTTTT FPMSNHTRER VTVAKLTLEN FYSNLILQHE ERETRQKKLE VAMEEEGLAD 60

EEKKLRRSQH ARKETEFLRL KRTRLGLDDF ESLKVIGRGA FGEVRLVQKK DTGHIYAMKI 120

LRKADMLEKE QVAHIRAERD ILVEADGAWV VKMFYSFQDK RNLYLIMEFL PGGDMMTLLM 180

KKDTLTEEET QFYISETVLA IDAIHQLGFI HRDIKPDNLL LDAKGHVKLS DFGLCTGLKK 240

AHRTEFYRNL THNPPSDFSF QNMNSKRKAE TWKKNRRQLA YSTVGTPDYI APEVFMQTGY 300

NKLCDWWSLG VIMYEMLIGY PPFCSETPQE TYRKVMNWKE TLVFPPEVPI SEKAKDLILR 360

FCIDSENRIG NSGIEEIKDH PFFEGVDWGH IRERPAAIPI EIKSIDDTSN FDEFPESDIL 420

QPVPNTTEPD YKSKDWVFLN YTYKRFEGLT QRGSIPSYMK AGKL 464

Nucleotide Sequence
(FASTA)

ATGGCAATGA CTGCGGGAAC TACAACAACT TTTCCCATGA GCAACCACAC CCGGGAAAGA 60

GTGACTGTAG CTAAACTCAC ATTGGAGAAT TTCTACAGCA ATCTAATTTT ACAGCATGAA 120

GAAAGAGAAA CCAGGCAAAA GAAGTTAGAG GTAGCTATGG AAGAAGAAGG ATTGGCAGAT 180

GAAGAGAAAA AATTACGGCG ATCACAGCAT GCTCGCAAAG AAACTGAATT TCTTAGACTC 240

AAAAGGACAA GGCTTGGCTT GGATGACTTC GAATCCCTGA AAGTTATAGG GAGAGGAGCC 300

TTTGGAGAGG TACGCCTTGT CCAGAAGAAA GACACAGGCC ATATCTATGC AATGAAGATA 360

TTGAGGAAGG CTGACATGCT TGAAAAAGAA CAGGTGGCCC ATATCCGAGC AGAGAGAGAT 420

ATATTGGTAG AAGCAGATGG TGCCTGGGTT GTGAAGATGT TTTATAGTTT TCAAGATAAA 480

AGGAATCTTT ATCTAATCAT GGAATTTCTC CCTGGAGGAG ACATGATGAC ATTACTAATG 540

AAGAAAGATA CCTTGACAGA AGAAGAAACC CAGTTCTATA TTTCAGAGAC TGTTCTGGCT 600

ATCGATGCAA TTCACCAGTT GGGGTTCATT CACCGAGATA TCAAACCAGA CAACCTCTTA 660

TTGGATGCCA AGGGACATGT AAAGTTATCT GATTTTGGCC TATGCACAGG CTTAAAGAAA 720

GCTCATAGGA CTGAATTTTA TAGGAACCTT ACACATAATC CACCAAGTGA TTTCTCATTT 780

CAGAACATGA ACTCAAAAAG AAAAGCAGAA ACGTGGAAGA AAAATAGGAG ACAACTGGCA 840

TATTCCACAG TTGGAACTCC AGATTACATT GCTCCAGAAG TATTCATGCA GACTGGGTAC 900

AACAAATTGT GTGACTGGTG GTCATTGGGA GTGATTATGT ATGAAATGCT AATCGGATAT 960

CCACCCTTCT GTTCTGAAAC ACCACAAGAA ACTTACAGGA AAGTTATGAA CTGGAAAGAA 1020

ACTCTAGTAT TTCCTCCAGA AGTACCTATA TCAGAGAAAG CCAAGGACCT GATTCTCAGA 1080

TTCTGTATTG ATTCGGAAAA CAGAATTGGA AACAGTGGAA TAGAGGAAAT CAAGGATCAT 1140

CCTTTTTTTG AAGGAGTAGA TTGGGGACAC ATCAGGGAGA GACCAGCAGC AATTCCCATA 1200

GAAATCAAAA GCATTGATGA TACATCAAAT TTTGATGAAT TTCCTGAATC TGATATCTTA 1260

CAACCAGTGC CAAATACCAC AGAACCGGAC TATAAATCCA AAGACTGGGT TTTTCTTAAT 1320

TATACCTATA AGCGGTTTGA AGGGCTTACT CAGCGTGGTT CTATCCCTTC CTACATGAAA 1380

GCTGGGAAAT TATGA 1395

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt+++ya+kilrk+d+l+k+qvah++aerdil+ead +w

Q: 90    FESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAW  149

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk+nlyl+me+lPGGd+mtll+kk++l+ee+++fyi+e+vla++++h+lGf

Q: 150   VVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGF  209

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+dakGh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+++++  ++ +

Q: 210   IHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKA  269

         *************************************************65555555555

S: 181   rkkkknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPflaetpq  240

            kknrr+lays+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++etpq

Q: 270   ETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQ  329

         555*********************************************************

S: 241   etykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         ety+kv+nwketl fp+ev++se+akdli r+++d+e+r+g++G++eik+hpff

Q: 330   ETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNSGIEEIKDHPFF  383

         *****************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHIYAMK ILRKADMLEK EQVAHIRAER DILVEADGAW 60

VVKMFYSFQD KRNLYLIMEF LPGGDMMTLL MKKDTLTEEE TQFYISETVL AIDAIHQLGF 120

IHRDIKPDNL LLDAKGHVKL SDFGLCTGLK KAHRTEFYRN LTHNPPSDFS FQNMNSKRKA 180

ETWKKNRRQL AYSTVGTPDY IAPEVFMQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYRKVMNWK ETLVFPPEVP ISEKAKDLIL RFCIDSENRI GNSGIEEIKD HPFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013