EKS-SAH-00155

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00155

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/RSKb	492.1	3.8E-148	343	600	258

Status

Unreviewed

Ensembl Protein

ENSSHAP00000014515

UniProt Accession

G3WGG0;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KA1

Gene Synonyms/Alias

RPS6KA1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000012391	ENSSHAP00000014515	ENSSHAT00000014637

Organism

Sarcophilus harrisii

Functional Description

Protein Length

660

Protein Sequence
(FASTA)

VFLVRKITRP DNGHLYAMKV LKKATLKVRD RVRTKMERDI LADVNHPFVV KLHYAFQTEG 60

KLYLILDFLR GGDLFTRLSK EVMFTEEDVK FYLAELALGL DHLHKLGIIY RDLKPENILL 120

DEEGHIKLTD FGLSKEAIDH EKKAYSFCGT VEYMAPEVVN RQGHTHSADW WSYGVLMFEM 180

LTGSLPFQGK DRKETMTLIL KAKLGMPQFL STEAQSLLRA LFKRNPANRL GSGTDGAEEI 240

KRHIFYSTID WNKLFRREIK PPFKPAVAQP DDTFYFDTEF TSRTPRDSPG IPPSAGAHQL 300

FRGFSFVATG LMEDDGKVRA PQAPLHSVVQ QLHGKSLVFS DGYVVKETIG VGSYSVCKRC 360

IHKATNMEYA VKVIDKSKRD PSEEIEILLR YGQHPNIITL KDVYDDGKHV YLVTELMRGG 420

ELLDKILRQK FFSEREASSV LHTLCRTMEY LHSQGVVHRD LKPSNILYVD ESGNPESIRI 480

CDFGFAKQLR AENGLLMTPC YTANFVAPEV LRRQGYDEGC DIWSLGILLY TMLAGYTPFA 540

NGPSDTPEEI LTRIGGGKFT LSGGNWDTIS ETAKDLVSKM LHVDPHRRLT AKQVLQHPWV 600

TQKDKLPQSQ LSHQDVQLVK GAMAATYSAL SSSKPTPQLK PIETSILAQR RVKKLPSTTL 660

Nucleotide Sequence
(FASTA)

GTCTTTCTGG TGAGGAAGAT CACCCGCCCA GACAACGGGC ACCTCTATGC CATGAAGGTA 60

CTGAAGAAAG CAACCCTGAA AGTTCGGGAT CGAGTCAGGA CCAAGATGGA AAGGGACATT 120

CTAGCTGACG TCAACCATCC GTTTGTGGTG AAGCTTCACT ATGCCTTCCA GACGGAGGGG 180

AAGCTCTACC TCATCTTGGA CTTCCTCCGG GGAGGAGACC TCTTCACACG CCTTTCCAAG 240

GAGGTCATGT TCACGGAAGA AGATGTGAAG TTCTACTTGG CTGAGCTGGC TCTGGGCCTG 300

GATCACCTGC ACAAGCTGGG GATCATTTAC CGAGACCTCA AACCCGAGAA CATTCTTCTG 360

GATGAAGAAG GACACATCAA ACTCACAGAT TTTGGCCTGA GCAAGGAGGC CATCGACCAT 420

GAGAAGAAAG CCTATTCCTT CTGTGGGACG GTGGAGTACA TGGCCCCCGA AGTTGTCAAC 480

CGACAAGGCC ACACGCACAG CGCTGACTGG TGGTCCTATG GGGTGCTGAT GTTTGAGATG 540

CTGACGGGCT CCCTGCCCTT CCAGGGGAAA GACCGGAAGG AGACCATGAC ACTGATTCTC 600

AAGGCAAAGC TGGGCATGCC CCAGTTTCTG AGCACTGAAG CACAAAGCCT CCTTCGAGCT 660

CTGTTCAAGC GGAATCCTGC CAACAGGCTG GGCTCTGGCA CTGATGGGGC TGAAGAGATC 720

AAGAGGCATA TCTTCTACTC CACCATAGAC TGGAACAAAC TGTTTCGTCG CGAGATCAAA 780

CCTCCCTTCA AGCCTGCCGT GGCCCAGCCC GATGACACCT TCTACTTTGA CACGGAGTTC 840

ACTTCCCGGA CACCCAGGGA CTCCCCGGGC ATCCCCCCCA GCGCCGGGGC TCACCAGCTC 900

TTCCGAGGCT TCAGCTTCGT GGCTACAGGC TTGATGGAAG ATGATGGCAA GGTCCGAGCC 960

CCCCAGGCCC CACTGCACTC GGTGGTCCAG CAACTTCATG GGAAGAGCTT GGTGTTCAGT 1020

GATGGCTACG TTGTGAAGGA GACCATCGGG GTTGGCTCTT ACTCCGTGTG CAAGCGCTGT 1080

ATCCACAAGG CCACCAACAT GGAATATGCG GTCAAGGTCA TCGACAAGAG CAAGAGGGAC 1140

CCCTCAGAGG AGATTGAGAT CCTTCTGCGC TATGGGCAAC ATCCCAATAT CATCACCCTG 1200

AAAGATGTGT ATGACGACGG CAAACACGTG TACCTGGTGA CGGAGCTGAT GCGAGGCGGG 1260

GAGCTCCTGG ACAAGATCCT CCGGCAGAAG TTCTTCTCGG AACGCGAGGC GAGCTCTGTC 1320

CTGCACACGC TCTGCCGGAC CATGGAGTAC CTGCACTCCC AGGGGGTAGT CCACAGGGAC 1380

CTGAAACCCA GCAACATCCT TTACGTGGAT GAGTCCGGGA ACCCCGAGAG CATCCGCATT 1440

TGTGACTTTG GCTTTGCTAA GCAGCTTCGA GCAGAGAACG GGCTCCTCAT GACTCCCTGC 1500

TATACTGCCA ACTTTGTGGC CCCAGAGGTT CTGAGGCGCC AGGGTTATGA CGAAGGCTGT 1560

GACATCTGGA GTCTGGGCAT CCTTCTCTAT ACCATGCTGG CTGGATACAC TCCCTTTGCA 1620

AATGGGCCCA GTGATACCCC AGAGGAGATC CTGACCCGGA TCGGGGGAGG AAAATTCACT 1680

CTCAGTGGCG GAAACTGGGA CACGATTTCA GAAACGGCCA AGGATCTAGT GTCCAAGATG 1740

CTCCATGTGG ACCCCCACCG ACGCCTGACT GCCAAGCAGG TTCTCCAGCA CCCGTGGGTC 1800

ACGCAGAAGG ACAAGCTCCC CCAGAGCCAG CTGTCCCATC AGGACGTGCA GCTAGTGAAG 1860

GGTGCCATGG CTGCCACCTA CTCTGCACTG AGCAGTTCCA AGCCCACCCC ACAGCTCAAG 1920

CCCATCGAGA CGTCCATCCT GGCCCAGCGA CGGGTGAAGA AGCTGCCTTC CACCACACTG 1980

TGA 1983

Domain Profile

S: 1     yevkedlGvGsysvckrcvhkatnqefavkiidkskrdtseeieillryeqhpnivtlkd  60

         y+vke++GvGsysvckrc+hkatn+e+avk+idkskrd+seeieillry+qhpni+tlkd

Q: 343   YVVKETIGVGSYSVCKRCIHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKD  402

         689*********************************************************

S: 61    vyddgkyvylvlellkGGelldrikkkkffsereasailrtlvkaveylheqGvvhrdlk  120

         vyddgk+vylv+el++GGelld+i+++kffsereas++l+tl++++eylh+qGvvhrdlk

Q: 403   VYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASSVLHTLCRTMEYLHSQGVVHRDLK  462

         ************************************************************

S: 121   penilyvdesdnaesikiidfGfaklkraengllktpcytlnfvapevlkrqGydeacdl  180

         p+nilyvdes+n+esi+i+dfGfak++raengll+tpcyt+nfvapevl+rqGyde+cd+

Q: 463   PSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLRRQGYDEGCDI  522

         ************************************************************

S: 181   wslGvllytmlaGyvpfangpedtaeeilakikeGkfslsGeawdsvseeakdlvskllt  240

         wslG+llytmlaGy+pfangp+dt+eeil++i+ Gkf+lsG++wd++se+akdlvsk+l+

Q: 523   WSLGILLYTMLAGYTPFANGPSDTPEEILTRIGGGKFTLSGGNWDTISETAKDLVSKMLH  582

         ************************************************************

S: 241   vdpakrlkleqllkhswl  258

         vdp++rl+++q+l+h+w+

Q: 583   VDPHRRLTAKQVLQHPWV  600

         *****************7

Domain Sequence
(FASTA)

YVVKETIGVG SYSVCKRCIH KATNMEYAVK VIDKSKRDPS EEIEILLRYG QHPNIITLKD 60

VYDDGKHVYL VTELMRGGEL LDKILRQKFF SEREASSVLH TLCRTMEYLH SQGVVHRDLK 120

PSNILYVDES GNPESIRICD FGFAKQLRAE NGLLMTPCYT ANFVAPEVLR RQGYDEGCDI 180

WSLGILLYTM LAGYTPFANG PSDTPEEILT RIGGGKFTLS GGNWDTISET AKDLVSKMLH 240

VDPHRRLTAK QVLQHPWV 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR016239	; Ribosomal_S6_kinase_II.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 2.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 2.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 2.
PS00108	; PROTEIN_KINASE_ST; 2.

Prints

Created Date

20-Feb-2013