EKS-SAH-00269

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00269

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	477.5	1.2E-143	516	777	262

Status

Unreviewed

Ensembl Protein

ENSSHAP00000016597

UniProt Accession

G3WME2;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN1

Gene Synonyms/Alias

ERN1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000014118	ENSSHAP00000016597	ENSSHAT00000016737

Organism

Sarcophilus harrisii

Functional Description

Protein Length

922

Protein Sequence
(FASTA)

YSLCTDPVLQ VPTHVEEPAF LPDPNDGSLY TLGGKNNEGL TKLPFTIPEL VQASPCRSSD 60

GILYMGKKQD IWYVVDLMTG EKQQTLSSAF AESLCPSTSL LYLGRTEYTI TMYDTKNREL 120

RWNATYFDYA ANVPEEDMEY KMSHFVSNGD GLVVTVDSES GDVLWIQNYA SPVVAFYIWH 180

REGLQKVMHT NVGVETLRYL TFMSGEVGRI TKWKYPFPKE TETKSKLTPT LYVGRYSTSL 240

YASPSMVHEG VAIVPRGSAF PQLEGPQTDG VTIKNNEECV ITPSIDLNID FGIKGKNKLN 300

YWTNYWLLIG HHEIPLSAST TVLEKFPNKL PRHRENVIHA DSEKSFEEKV IKIVDRDTEE 360

PTPATHQDIE FTRTPVKTEA AVDSILKDMA TIILCTFLLI GWVAFVITYP MSMHQQQQLQ 420

HQQFQRQLEE RIQLLQQQQL PFQTPGDLAQ DSDFLDTSAG LHSESSAPSS PNMSPKGSNH 480

SQHSSNSASK VSGSITTEQD EDDEETSMVV VGKISFCPKD VLGHGAEGTI VYRGMFDNRA 540

VAVKRILPEC FSFADREVQL LRESDEHPNV IRYFCTERDR QFQYIAIELC AATLQEYVEQ 600

KDFAHLGLEP ITLLQQTTSG LAYLHSLNIV HRDLKPHNIL LSMPNAHGKI KAMISDFGLC 660

KKLAVGRHSF SRRSGVPGTE GWIAPEMLSE DCKENPTYTV DIFSAGCVFY YVISDGNHPF 720

GKSLQRQANI LLGAYSLNCL HPEKHEDIVA HELIEKMIAM DPQKRPSAKH VLKHPFFWGL 780

EKQLQFFQDV SDRIEKEALD GPIVKQLERG GRMVVKMDWR ENITVPLSDY LRKFRTYKGG 840

SVRDLLRAMR NKKHHYRELP EDVQETLGSI PDDFVRYFTS RFPHLLSHTY RAMELCSHER 900

LFQPYYFQEA TELDPPVTND GL 922

Nucleotide Sequence
(FASTA)

TATTCTCTTT GTACAGATCC AGTCCTGCAA GTTCCCACCC ACGTTGAAGA GCCTGCATTC 60

CTTCCAGACC CCAATGATGG AAGCTTGTAT ACACTTGGTG GTAAAAACAA TGAAGGTCTG 120

ACGAAACTTC CCTTTACCAT CCCAGAATTG GTGCAGGCAT CCCCATGCCG AAGTTCAGAT 180

GGGATTCTCT ATATGGGTAA GAAGCAGGAC ATTTGGTACG TTGTTGACCT TATGACTGGA 240

GAGAAGCAGC AGACTTTGTC TTCAGCATTT GCAGAAAGCC TCTGTCCATC CACCTCTCTT 300

CTGTATCTTG GACGCACAGA GTACACCATC ACCATGTATG ATACGAAGAA CCGAGAGCTT 360

CGGTGGAATG CTACCTATTT TGATTATGCG GCTAATGTAC CAGAAGAAGA CATGGAGTAC 420

AAGATGTCCC ACTTTGTGTC CAATGGGGAC GGGCTGGTGG TGACCGTGGA CAGTGAATCT 480

GGAGATGTCC TGTGGATTCA GAATTACGCC TCGCCGGTGG TGGCCTTCTA CATCTGGCAT 540

CGGGAAGGCC TGCAGAAGGT GATGCACACC AACGTTGGGG TGGAGACGCT GCGCTATCTG 600

ACCTTCATGT CTGGAGAGGT GGGGCGTATC ACCAAGTGGA AATACCCCTT CCCAAAGGAG 660

ACCGAGACCA AGAGCAAATT GACGCCCACC CTCTATGTTG GGAGATATTC CACCAGCCTG 720

TACGCCTCCC CATCCATGGT CCATGAAGGA GTCGCCATTG TGCCTCGAGG CAGTGCCTTT 780

CCCCAACTGG AAGGCCCCCA GACAGATGGT GTCACGATCA AAAATAATGA AGAATGTGTG 840

ATTACCCCCA GCATAGACCT GAACATTGAT TTTGGAATCA AAGGAAAGAA TAAACTCAAC 900

TATTGGACCA ATTATTGGCT TCTCATTGGA CATCATGAGA TCCCACTATC TGCTTCTACC 960

ACAGTCTTGG AAAAATTCCC CAATAAACTG CCCAGACATC GTGAAAATGT GATCCATGCT 1020

GATTCAGAGA AGAGTTTTGA GGAGAAGGTT ATCAAAATAG TTGACCGGGA CACAGAAGAA 1080

CCAACTCCTG CTACTCATCA AGATATTGAA TTCACTCGAA CCCCAGTAAA AACAGAGGCA 1140

GCTGTGGACT CCATTTTGAA GGACATGGCT ACAATCATCC TGTGTACCTT TCTTCTTATT 1200

GGATGGGTCG CCTTTGTCAT CACGTACCCA ATGAGCATGC ACCAGCAACA GCAACTCCAG 1260

CACCAGCAAT TTCAGAGGCA ACTGGAAGAG AGGATCCAGC TGCTACAACA ACAGCAGCTT 1320

CCTTTCCAAA CTCCTGGTGA CCTGGCTCAG GACTCGGATT TCCTGGATAC TTCTGCTGGT 1380

TTGCACTCAG AGAGCTCAGC TCCCAGCAGC CCCAACATGT CCCCGAAGGG CTCCAACCAC 1440

TCTCAGCATT CCAGCAATTC GGCTTCCAAG GTTAGCGGCA GCATCACCAC TGAGCAAGAT 1500

GAGGACGATG AAGAGACCAG CATGGTTGTG GTTGGGAAAA TTTCCTTTTG CCCAAAGGAT 1560

GTCTTGGGAC ATGGAGCTGA AGGCACAATC GTATATCGGG GGATGTTTGA CAATCGAGCT 1620

GTGGCAGTGA AGAGGATACT CCCAGAGTGC TTCAGTTTTG CAGACCGTGA GGTGCAGCTG 1680

CTTCGGGAAT CCGACGAGCA CCCCAATGTG ATTCGTTATT TCTGCACGGA GCGGGACCGT 1740

CAGTTCCAAT ATATTGCCAT TGAACTGTGT GCAGCCACTT TGCAAGAGTA CGTGGAACAG 1800

AAGGACTTTG CTCACCTTGG CTTAGAACCC ATCACCTTGT TGCAGCAGAC AACATCGGGA 1860

CTTGCTTACC TTCATTCCCT CAACATTGTT CACAGAGACC TGAAACCCCA TAACATCCTC 1920

CTTTCTATGC CCAATGCACA CGGTAAGATC AAAGCTATGA TCTCTGACTT TGGTCTCTGC 1980

AAGAAGCTGG CAGTAGGAAG GCACAGTTTC AGTCGCCGCT CTGGAGTACC AGGCACTGAG 2040

GGATGGATTG CTCCAGAGAT GCTGAGTGAA GATTGCAAAG AGAATCCAAC TTATACAGTG 2100

GACATCTTCT CTGCGGGCTG TGTCTTTTAC TATGTGATAT CTGACGGCAA TCACCCATTT 2160

GGCAAGTCCC TGCAGCGGCA AGCCAATATT CTCCTTGGTG CCTACAGCCT TAACTGTTTG 2220

CACCCAGAGA AGCATGAAGA CATCGTTGCT CATGAACTAA TAGAAAAAAT GATTGCTATG 2280

GATCCCCAGA AACGACCCTC AGCCAAGCAC GTGCTGAAAC ACCCATTCTT CTGGGGCTTA 2340

GAAAAGCAGC TACAATTCTT TCAGGACGTG AGTGACCGGA TAGAGAAGGA GGCCTTAGAT 2400

GGTCCCATAG TGAAACAACT AGAAAGAGGA GGGAGAATGG TAGTCAAAAT GGACTGGAGG 2460

GAAAACATAA CTGTTCCACT AAGTGACTAT CTTCGAAAAT TCAGAACCTA TAAAGGGGGT 2520

TCTGTAAGAG ATCTTCTTCG TGCAATGAGA AATAAGAAAC ACCACTACCG AGAACTCCCC 2580

GAAGATGTAC AGGAAACATT GGGCTCAATC CCTGATGATT TTGTCCGTTA TTTCACATCA 2640

CGGTTCCCCC ACCTCCTTTC CCACACCTAC CGAGCCATGG AACTGTGTAG CCATGAGAGA 2700

CTCTTCCAGC CTTACTATTT CCAAGAGGCC ACAGAACTGG ACCCCCCAGT GACAAATGAT 2760

GGCCTCTGA 2769

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f+pkdvlG+GaeGt+v+rG+f++r+vavkr+l+e++++a+rev+llresdehpnviryfc

Q: 516   FCPKDVLGHGAEGTIVYRGMFDNRAVAVKRILPECFSFADREVQLLRESDEHPNVIRYFC  575

         79**********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         te+drqf+yia+elcaa+lq+yve+kd++ + +lepi+ll+q++sGla+lhsl+ivhrdl

Q: 576   TERDRQFQYIAIELCAATLQEYVEQKDFA-HLGLEPITLLQQTTSGLAYLHSLNIVHRDL  634

         *****************************.******************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp+nil+s+p+a+gk++++isdfGlckkl+vG++sfsrrsgv+GteGwiape+l+e++ke

Q: 635   KPHNILLSMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKE  694

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++t++vdifs+Gcvfyyv+s+G+hpfG+sl+rqanil g++sl++l++ek+e+++a++li

Q: 695   NPTYTVDIFSAGCVFYYVISDGNHPFGKSLQRQANILLGAYSLNCLHPEKHEDIVAHELI  754

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         +kmi++dp+krpsak+vlkhp+f

Q: 755   EKMIAMDPQKRPSAKHVLKHPFF  777

         **********************9

Domain Sequence
(FASTA)

FCPKDVLGHG AEGTIVYRGM FDNRAVAVKR ILPECFSFAD REVQLLRESD EHPNVIRYFC 60

TERDRQFQYI AIELCAATLQ EYVEQKDFAH LGLEPITLLQ QTTSGLAYLH SLNIVHRDLK 120

PHNILLSMPN AHGKIKAMIS DFGLCKKLAV GRHSFSRRSG VPGTEGWIAP EMLSEDCKEN 180

PTYTVDIFSA GCVFYYVISD GNHPFGKSLQ RQANILLGAY SLNCLHPEKH EDIVAHELIE 240

KMIAMDPQKR PSAKHVLKHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 4.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013