EKS-SAH-00229

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00229

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	340.0	8.0E-102	27	279	253

Status

Unreviewed

Ensembl Protein

ENSSHAP00000016650

UniProt Accession

G3WMJ5;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA1

Gene Synonyms/Alias

PRKAA1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000014164	ENSSHAP00000016650	ENSSHAT00000016790

Organism

Sarcophilus harrisii

Functional Description

Protein Length

559

Protein Sequence
(FASTA)

MRRLSTWRKM AAAEKQKHDG RVKIGHYILG DTLGVGTFGK VKVGKHELTG HKVAVKILNR 60

QKIRSLDVVG KIRREIQNLK LFRHPHIIKL YQVISTPSDI FMVMEYVSGG ELFDYICKNG 120

RLDEKESRRL FQQILSGVDY CHRHMVVHRD LKPENVLLDA HMNAKIADFG LSNMMSDGEF 180

LRTSCGSPNY AAPEVISGRL YAGPEVDIWS SGVILYALLC GTLPFDDDHV PTLFKKICDG 240

IFYTPQYLNP SVISLLKHML QVDPMKRATI KDIREHEWFK QDLPKYLFPE DPSYSSTMID 300

DEALKEVCEK FECTEEEVLS CLYSRNHQDP LAVAYHLIID NRRIMNEAKD FYLATSPPDS 360

FLDDHHFSRP HPERVPFLVA ETPRSRHTLD ELNPQKSKHQ GVRRAKWHLG IRSQSRPNDI 420

MAEVCRSIKQ LDYEWKVVNP YYLRVRRKNP VTSTYSKMSL QLYQVDSRTY LLDFRSIDDE 480

ITEAKSGTTT PQRSGSVSNY RSCQKNDSDA EAQGRSSDVS LTSSVTSLDS STVDLTPRPG 540

SHTIEFFEMC ANLIKILAQ 559

Nucleotide Sequence
(FASTA)

ATGCGCAGGC TCAGTACCTG GAGGAAGATG GCGGCGGCGG AGAAGCAGAA ACACGACGGG 60

CGAGTGAAGA TTGGCCACTA CATCCTGGGG GACACGCTGG GGGTCGGCAC CTTCGGCAAA 120

GTGAAGGTTG GCAAGCATGA GTTGACTGGG CACAAAGTTG CTGTGAAGAT CTTAAATCGA 180

CAGAAAATTC GAAGTCTTGA TGTGGTAGGG AAAATTCGCA GAGAAATTCA AAACCTTAAG 240

CTTTTCAGAC ATCCTCATAT CATTAAGCTG TACCAGGTCA TTAGTACACC ATCTGACATT 300

TTCATGGTGA TGGAATATGT CTCTGGGGGA GAACTATTTG ATTATATCTG TAAAAATGGC 360

AGGCTGGATG AGAAAGAGAG TCGGCGTTTA TTTCAACAAA TCCTTTCTGG TGTGGATTAT 420

TGTCACAGGC ACATGGTTGT CCATAGAGAC TTGAAACCTG AAAATGTTTT GCTTGATGCA 480

CACATGAATG CAAAAATAGC TGATTTTGGT CTTTCAAATA TGATGTCAGA TGGCGAATTT 540

TTAAGAACAA GCTGTGGCTC TCCCAACTAT GCTGCACCAG AAGTAATTTC AGGAAGGTTA 600

TATGCAGGTC CAGAGGTAGA TATTTGGAGC AGTGGTGTTA TTCTTTATGC TCTGTTATGT 660

GGCACCCTTC CATTTGATGA TGATCATGTG CCAACTCTTT TTAAGAAGAT ATGTGATGGG 720

ATCTTTTATA CTCCTCAGTA CTTGAATCCT TCTGTGATTA GCCTTCTGAA ACATATGCTG 780

CAGGTGGATC CCATGAAGAG AGCCACAATC AAAGATATCA GGGAACATGA GTGGTTTAAA 840

CAAGATCTTC CAAAGTATCT CTTTCCTGAG GATCCATCAT ATAGTTCAAC CATGATTGAT 900

GATGAAGCCT TAAAAGAAGT ATGTGAAAAA TTTGAATGTA CAGAGGAAGA GGTTCTCAGC 960

TGTCTGTATA GCAGAAACCA CCAGGACCCT TTGGCAGTTG CTTATCACCT CATAATAGAT 1020

AATAGGAGAA TAATGAATGA GGCCAAAGAT TTCTATTTAG CTACAAGCCC ACCAGATTCT 1080

TTCTTAGATG ATCACCATTT TTCTCGTCCA CATCCTGAAA GAGTGCCATT CTTGGTTGCG 1140

GAAACACCAA GGTCACGCCA TACATTGGAT GAATTAAATC CTCAAAAATC CAAACACCAG 1200

GGTGTAAGGA GGGCAAAATG GCATTTGGGA ATTCGAAGTC AAAGTAGACC AAATGACATC 1260

ATGGCAGAAG TTTGTCGCTC AATTAAACAA TTGGATTATG AATGGAAGGT TGTAAACCCA 1320

TATTATTTGC GTGTTCGAAG GAAGAATCCA GTGACAAGCA CTTATTCAAA AATGAGTCTA 1380

CAGTTATACC AGGTGGACAG TAGAACTTAC TTATTGGATT TCCGAAGCAT TGATGATGAA 1440

ATTACTGAAG CCAAATCTGG AACTACTACT CCACAAAGAT CAGGTTCTGT GAGCAATTAT 1500

CGATCTTGCC AAAAGAATGA CTCAGATGCT GAAGCCCAAG GAAGATCCTC GGATGTTTCC 1560

CTTACCTCAT CAGTGACTTC ACTTGACTCT TCTACAGTTG ACTTAACCCC AAGGCCAGGA 1620

AGTCACACAA TAGAGTTTTT TGAGATGTGT GCAAATCTTA TTAAAATTCT TGCACAGTAA 1680

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk+ kh++t++kvavKi++++k+ s + + ki+rEi+ lk ++hp+

Q: 27    YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIrSLDVVGKIRREIQNLKLFRHPH  86

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++grl+eke+r+lf+q++s+v+Y+h++ +

Q: 87    IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV  146

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 147   VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV  206

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws Gv+Lyal++g+lPfd++++ +l++ki +g + +p++l+++++sLl+++L+vdp k

Q: 207   DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMK  266

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati++i++hew+

Q: 267   RATIKDIREHEWF  279

         ************7

Domain Sequence
(FASTA)

YILGDTLGVG TFGKVKVGKH ELTGHKVAVK ILNRQKIRSL DVVGKIRREI QNLKLFRHPH 60

IIKLYQVIST PSDIFMVMEY VSGGELFDYI CKNGRLDEKE SRRLFQQILS GVDYCHRHMV 120

VHRDLKPENV LLDAHMNAKI ADFGLSNMMS DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSSGVILY ALLCGTLPFD DDHVPTLFKK ICDGIFYTPQ YLNPSVISLL KHMLQVDPMK 240

RATIKDIREH EWF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013