EKS-SAH-00214

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00214

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	382.3	1.3E-114	55	315	261

Status

Unreviewed

Ensembl Protein

ENSSHAP00000016895

UniProt Accession

G3WN90;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K3

Gene Synonyms/Alias

MAP2K3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000014370	ENSSHAP00000016895	ENSSHAT00000017037

Organism

Sarcophilus harrisii

Functional Description

Protein Length

337

Protein Sequence
(FASTA)

MSVPRGKIKN RKDLKISCVS NKPPVSNPTP PRNLDSRTFI TIGDKNFEVA ADDLVSISEL 60

GRGAYGVVEK VRHAQSGTIM AVKRIRATVN TQEQKRLLMD LDISMRTVDC FYTVTFYGAL 120

FREGDVWICM ELMDTSLDKF YKKVLEKEMT IPEDILGEIA VSIVRALEHL HSKLSVIHRD 180

VKPSNVLINK EGHVKMCDFG ISGYLVDSVA KTMDAGCKPY MAPERINPEL NQKGYNVKSD 240

VWSLGITMIE MAILRFPYES WGTPFQQLKQ VVEEPSPQLP ADRFSPEFVD FTAQCLRKNP 300

AERMSYLQLM EHPFFTLHKT KETDIAAFVK EILGEDS 337

Nucleotide Sequence
(FASTA)

ATGTCGGTCC CCAGAGGAAA AATCAAGAAC AGAAAGGATT TAAAAATATC ATGTGTCTCC 60

AACAAGCCAC CCGTCTCCAA CCCAACGCCT CCTAGGAACC TGGACTCTAG GACCTTCATT 120

ACAATTGGTG ACAAGAACTT TGAAGTGGCA GCTGATGACT TAGTTTCCAT ATCAGAGTTG 180

GGTCGGGGTG CCTATGGAGT AGTGGAGAAA GTTCGACATG CTCAGAGTGG AACCATCATG 240

GCTGTCAAGA GGATCCGAGC GACTGTGAAC ACTCAGGAAC AGAAGAGGCT TCTCATGGAT 300

CTGGATATCT CCATGAGGAC TGTTGACTGC TTCTATACTG TCACCTTCTA TGGGGCCCTT 360

TTCAGAGAGG GAGATGTATG GATCTGTATG GAACTGATGG ACACATCCTT GGACAAATTT 420

TATAAGAAGG TTCTGGAGAA GGAGATGACC ATACCAGAGG ATATTCTAGG CGAAATAGCA 480

GTGTCTATTG TTCGAGCTCT GGAGCACTTA CATAGTAAAC TGTCTGTGAT TCACAGAGAT 540

GTCAAGCCAT CCAATGTTCT TATCAACAAG GAAGGCCACG TAAAAATGTG TGACTTTGGG 600

ATCAGTGGCT ACTTGGTGGA TTCAGTTGCC AAAACCATGG ATGCTGGTTG CAAACCCTAT 660

ATGGCGCCAG AGAGAATCAA CCCGGAGCTG AACCAAAAAG GGTATAATGT CAAGTCAGAT 720

GTCTGGAGCC TGGGAATCAC TATGATTGAG ATGGCAATTC TTCGGTTTCC ATATGAGTCA 780

TGGGGGACCC CATTCCAGCA GCTGAAACAA GTGGTAGAAG AGCCTTCTCC CCAGCTCCCT 840

GCCGATCGCT TCTCTCCCGA GTTTGTGGAC TTCACAGCCC AGTGCTTGAG GAAGAATCCC 900

GCAGAGCGAA TGAGCTACCT GCAGCTAATG GAGCATCCTT TCTTCACTTT GCACAAAACC 960

AAAGAGACAG ACATCGCCGC CTTTGTGAAG GAGATCCTGG GCGAGGACTC ATAG 1014

Domain Profile

S: 2     ekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyiv  61

          +++elG+G++gvVekv+h +sg+i+avK+ir++++++eqk++l++l++ +++ ++ y+v

Q: 55    VSISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNTQEQKRLLMDLDISMRTVDCFYTV  114

         6789********************************************************

S: 62    kfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylkek  121

         +fyGa+++egdv+icmelmd tsldk++kkvlek+ +ipe++lg+iav++v+ale+l++k

Q: 115   TFYGALFREGDVWICMELMD-TSLDKFYKKVLEKEMTIPEDILGEIAVSIVRALEHLHSK  173

         ********************.***************************************

S: 122   lkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg...kk  177

         l++iHRDvKPsN+L+n++G+vK+CDFG+sg+lvds+Ak++ +G+k+YmaPEri++   +k

Q: 174   LSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMdAGCKPYMAPERINPelnQK  233

         *******************************************************99999

S: 178   kYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpeeefseefqefvs  237

          Y+vksdvWslG+t++e+a+ r+pye++ +++++lk++v+e++p+lp+++fs+ef++f +

Q: 234   GYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFTA  293

         ************************************************************

S: 238   kClkkdekeRpklkellkhafi  259

         +Cl+k+++eR+++ +l++h+f+

Q: 294   QCLRKNPAERMSYLQLMEHPFF  315

         ********************96

Domain Sequence
(FASTA)

VSISELGRGA YGVVEKVRHA QSGTIMAVKR IRATVNTQEQ KRLLMDLDIS MRTVDCFYTV 60

TFYGALFREG DVWICMELMD TSLDKFYKKV LEKEMTIPED ILGEIAVSIV RALEHLHSKL 120

SVIHRDVKPS NVLINKEGHV KMCDFGISGY LVDSVAKTMD AGCKPYMAPE RINPELNQKG 180

YNVKSDVWSL GITMIEMAIL RFPYESWGTP FQQLKQVVEE PSPQLPADRF SPEFVDFTAQ 240

CLRKNPAERM SYLQLMEHPF F 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013