EKS-SAH-00386

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00386

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	423.2	3.9E-127	35	293	259

Status

Unreviewed

Ensembl Protein

ENSSHAP00000017448

UniProt Accession

G3WPU3;

Protein Name

Protein Synonyms/Alias

Gene Name

STK17B

Gene Synonyms/Alias

STK17B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000014825	ENSSHAP00000017448	ENSSHAT00000017593

Organism

Sarcophilus harrisii

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MSRRRFDCRS LSGMLSTAIQ TPIKTENFHN FYMLTSKELG RGKFAVVRQC ISKSTDQEYA 60

AKFLKKRRRG QDCRAEILHE IAVLELTESS SRVINLHEVY ETSNEIILVL EYAAGGEIFN 120

LCLPDLVEMV SENDIIRLIR QILEGVSYLH HNNIVHLDLK PQNILLSSIS PLGDIKIVDF 180

GMSRKIGNAC ELREIMGTPE YLAPEVLNYD PITTATDMWN VGIITYMLLM HTSPFVGEDN 240

QETYLNISQV NVDYSEEMFS SVSQLAKDFI QCLLVKNPED RPTAEDCLSH PWLQQRDFVD 300

LFHPEETSCS SQTQEHTVRS LEDKTTKSTC NGTCGDREDK ENIPEDISTV SKRFRFDDSL 360

HNPQELVPDL LC 372

Nucleotide Sequence
(FASTA)

ATGTCTAGAA GAAGATTTGA TTGCCGGAGC CTCTCAGGCA TGCTGTCTAC AGCTATCCAA 60

ACTCCAATAA AAACAGAAAA TTTTCACAAT TTTTACATGC TCACATCTAA GGAGCTGGGC 120

AGAGGAAAGT TTGCTGTGGT CAGACAATGT ATTTCAAAAT CCACTGACCA AGAATATGCT 180

GCTAAATTTC TAAAGAAGAG AAGAAGAGGC CAAGATTGTC GAGCAGAAAT CCTACATGAA 240

ATTGCTGTGC TAGAATTAAC AGAGTCCAGT TCTCGTGTGA TTAATCTCCA TGAAGTCTAT 300

GAAACTTCAA ATGAAATCAT TCTGGTATTG GAGTATGCTG CAGGTGGAGA AATTTTCAAC 360

CTATGCTTAC CTGACCTTGT TGAAATGGTC TCGGAAAATG ATATCATCAG ACTTATTAGA 420

CAAATATTAG AAGGAGTTTC TTATCTACAT CACAACAATA TTGTGCACCT TGATTTGAAG 480

CCTCAAAATA TCTTATTAAG CAGCATTTCT CCACTTGGAG ACATAAAAAT TGTAGATTTT 540

GGAATGTCTC GGAAAATAGG GAATGCATGT GAATTGAGAG AGATAATGGG AACTCCCGAA 600

TACCTAGCTC CAGAAGTATT GAACTATGAT CCTATTACCA CAGCAACAGA CATGTGGAAT 660

GTTGGCATAA TCACATACAT GTTACTAATG CATACATCTC CATTTGTGGG AGAAGACAAT 720

CAAGAAACAT ACCTCAATAT TTCCCAAGTC AATGTGGATT ATTCTGAAGA AATGTTTTCA 780

TCAGTCTCAC AGCTGGCCAA AGACTTTATT CAGTGTCTTT TAGTAAAAAA CCCAGAGGAC 840

AGACCAACAG CAGAAGACTG TTTGTCTCAT CCTTGGCTCC AGCAAAGGGA TTTTGTGGAC 900

TTGTTTCATC CTGAAGAAAC TTCCTGTTCT TCTCAAACTC AAGAGCACAC AGTCAGAAGC 960

TTAGAAGACA AAACCACTAA ATCTACTTGT AATGGAACCT GTGGAGACCG AGAAGATAAA 1020

GAGAATATTC CTGAGGACAT TAGTACGGTT TCCAAAAGAT TTCGTTTTGA TGATTCCTTG 1080

CATAACCCCC AGGAACTTGT TCCAGATCTG TTATGTTAG 1119

Domain Profile

S: 3     tgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirse  62

         t+kelg+Gkfavvr+c++kst +eyaakflkkrr    r++++r+ei +e+avl++ +s+

Q: 35    TSKELGRGKFAVVRQCISKSTDQEYAAKFLKKRR----RGQDCRAEILHEIAVLELTESS  90

         789*******************************....**********************

S: 63    pnvinlhevyenksdvililelvaGGelfd..llaekeslseeeatellkqilegvkylh  120

         ++vinlhevye+  ++il+le++aGGe+f+  l +  e++se+++++l++qilegv ylh

Q: 91    SRVINLHEVYETSNEIILVLEYAAGGEIFNlcLPDLVEMVSENDIIRLIRQILEGVSYLH  150

         ******************************7778999***********************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivny  180

         +++ivhldlkP+nill++ + p gdik++dfG+srki +++el+ei+GtPe++aPe++ny

Q: 151   HNNIVHLDLKPQNILLSSIS-PLGDIKIVDFGMSRKIGNACELREIMGTPEYLAPEVLNY  209

         ********************.***************************************

S: 181   eplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdf  240

         +p++++tdmw++G+ity+ll ++sPf+G+++qet+lnis+vn+d+see+fssvs+lakdf

Q: 210   DPITTATDMWNVGIITYMLLMHTSPFVGEDNQETYLNISQVNVDYSEEMFSSVSQLAKDF  269

         ************************************************************

S: 241   irrllvkdpekrltieeclehswl  264

         i+ llvk+pe+r t+e+cl+h+wl

Q: 270   IQCLLVKNPEDRPTAEDCLSHPWL  293

         ***********************7

Domain Sequence
(FASTA)

TSKELGRGKF AVVRQCISKS TDQEYAAKFL KKRRRGQDCR AEILHEIAVL ELTESSSRVI 60

NLHEVYETSN EIILVLEYAA GGEIFNLCLP DLVEMVSEND IIRLIRQILE GVSYLHHNNI 120

VHLDLKPQNI LLSSISPLGD IKIVDFGMSR KIGNACELRE IMGTPEYLAP EVLNYDPITT 180

ATDMWNVGII TYMLLMHTSP FVGEDNQETY LNISQVNVDY SEEMFSSVSQ LAKDFIQCLL 240

VKNPEDRPTA EDCLSHPWL 259

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013