EKS-SAH-00199

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00199

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	481.4	7.2E-145	4	286	283

Status

Unreviewed

Ensembl Protein

ENSSHAP00000019181

UniProt Accession

G3WUS6;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000016286	ENSSHAP00000019181	ENSSHAT00000019337

Organism

Sarcophilus harrisii

Functional Description

Protein Length

587

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKHKDTGQIV AIKIFYEKPE KSVNKIAMRE IKFLKQFRHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTVLDEL QHCCHGLESK RLRKYLFQIL RAIEYLHNNN 120

IIHRDIKPEN ILVSQSGITK LCDFGFARTL AAPGDIYTDY VATRWYRAPE LVLKDTTYGK 180

PVDIWALGCM IVEMATGNPY LPSSSDLDLL HKIVIKVGNL TPHLQNVFSR SPIFVGVVLP 240

QVQHPKNARK KYPKLNGLLA DIVHACLQID PAERVSSTDL LNHDYFTRDG FIERFIPEFR 300

AKLLQEARIN SFIKPKENSK EIELTKEDRK TTHGNTLPSS SIIGKDGDKD KKTKDIKVRI 360

FKVKGGKGDV SESEYYQRDS SENFYTLSQD NKPVTSESPI PANLNNDSNN MKEDVYGGGC 420

MTMPPINPNS SNLTAANPNS HFTHIITSNK PSEKAKKRRT SSQSLTQSIS NKQEDAGSVQ 480

NQTEKSTLYE RTAQNDHITN GNKRKLNLLR NDKKEIHFPE LPFTIQSKEI KGMEVKQIKM 540

LKREPKKTDT SKIPSLLNVD QNQEKTEGEE AHCEGKNLKR KFFLIVV 587

Nucleotide Sequence
(FASTA)

ATGGAGATGT ATGAAACCCT TGGAAAAGTG GGAGAGGGAA GTTATGGAAC GGTCATGAAG 60

TGTAAACATA AGGATACTGG GCAGATAGTA GCCATTAAGA TATTTTATGA AAAACCGGAA 120

AAATCTGTCA ACAAAATTGC AATGAGAGAA ATAAAGTTTC TAAAGCAGTT TCGCCATGAA 180

AATCTGGTCA ATCTAATTGA AGTATTCAGA CAAAAAAAGA AAATTCATTT GGTATTTGAA 240

TTTATTGATC ACACAGTTTT AGATGAGTTA CAGCATTGCT GTCATGGACT TGAAAGTAAA 300

CGACTAAGAA AATATCTTTT CCAAATCCTT CGGGCCATAG AATATCTTCA CAACAATAAT 360

ATTATTCATC GGGATATAAA ACCTGAGAAT ATTTTAGTAT CTCAGTCTGG AATTACTAAA 420

CTCTGTGATT TTGGTTTTGC TCGGACATTA GCAGCCCCTG GAGACATTTA TACAGACTAT 480

GTGGCTACCC GCTGGTATAG AGCGCCTGAA TTAGTATTAA AAGATACTAC TTACGGAAAA 540

CCTGTGGATA TTTGGGCTTT AGGTTGCATG ATCGTTGAGA TGGCCACAGG GAACCCATAT 600

CTTCCTAGTA GTTCTGACTT GGATTTGCTC CACAAAATTG TGATAAAAGT AGGTAATTTG 660

ACACCTCACT TGCAGAATGT TTTTTCCAGG AGTCCTATTT TTGTTGGGGT AGTTCTTCCT 720

CAAGTTCAGC ACCCTAAAAA TGCAAGAAAA AAGTATCCGA AGCTAAATGG ATTATTGGCA 780

GACATAGTCC ATGCTTGTTT ACAAATTGAT CCTGCTGAAA GGGTGTCATC CACAGATCTT 840

CTGAATCATG ACTATTTTAC TAGAGATGGG TTTATTGAAA GATTCATACC AGAATTTAGG 900

GCTAAGTTAC TGCAAGAAGC AAGAATCAAT TCATTCATAA AGCCCAAAGA GAATTCTAAA 960

GAAATTGAAC TCACTAAAGA AGACAGGAAA ACAACCCATG GAAATACATT GCCAAGTAGT 1020

TCAATTATAG GAAAGGATGG GGACAAGGAC AAAAAGACCA AGGATATAAA AGTCCGAATT 1080

TTTAAAGTAA AAGGAGGGAA AGGAGACGTT TCTGAAAGTG AATATTACCA ACGGGACAGT 1140

TCAGAAAATT TTTATACTCT TTCTCAAGAT AATAAACCTG TAACATCTGA ATCACCTATC 1200

CCTGCAAATC TCAACAATGA TTCTAACAAC ATGAAGGAAG ATGTCTATGG AGGCGGGTGT 1260

ATGACTATGC CACCCATTAA TCCTAATAGC AGTAATTTGA CTGCTGCAAA TCCTAACTCA 1320

CATTTCACCC ACATAATTAC AAGTAATAAG CCATCTGAAA AAGCTAAAAA GAGAAGGACT 1380

TCCTCACAGT CTCTTACACA GTCCATATCT AACAAGCAAG AGGATGCAGG CTCTGTACAG 1440

AATCAAACAG AGAAGAGCAC ACTTTATGAG CGAACAGCTC AAAATGACCA TATAACAAAT 1500

GGGAATAAAA GGAAACTGAA TCTTTTAAGG AATGATAAGA AAGAGATACA TTTCCCAGAG 1560

CTGCCTTTCA CAATACAGTC CAAAGAAATT AAAGGAATGG AAGTTAAACA GATAAAGATG 1620

CTGAAGAGGG AACCAAAGAA AACTGACACA TCTAAAATAC CATCTTTACT TAATGTGGAT 1680

CAAAACCAGG AAAAAACAGA GGGAGAAGAA GCCCATTGTG AAGGGAAGAA TTTGAAAAGA 1740

AAATTTTTTC TCATTGTAGT A 1761

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++kdtgqivaik f+e+++ k+v+kia+reik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPE-KSVNKIAMREIKFLKQFRHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+tvldel++ ++G+e+++++k+l+qil+aie++h+nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTVLDELQHCCHGLESKRLRKYLFQILRAIEYLHNNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg++klcdfGfar+laapgd+ytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTTYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q++fs++++f Gv+lp+v

Q: 183   DIWALGCMIVEMATGNPYLPSSSDLDLLHKIVIKVGNLTPHLQNVFSRSPIFVGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++++++kkypkln +l+d++++cl++dpaer+s+++ll+h+yf

Q: 243   QHPKNARKKYPKLNGLLADIVHACLQIDPAERVSSTDLLNHDYF  286

         *******************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KDTGQIVAIK IFYEKPEKSV NKIAMREIKF LKQFRHENLV 60

NLIEVFRQKK KIHLVFEFID HTVLDELQHC CHGLESKRLR KYLFQILRAI EYLHNNNIIH 120

RDIKPENILV SQSGITKLCD FGFARTLAAP GDIYTDYVAT RWYRAPELVL KDTTYGKPVD 180

IWALGCMIVE MATGNPYLPS SSDLDLLHKI VIKVGNLTPH LQNVFSRSPI FVGVVLPQVQ 240

HPKNARKKYP KLNGLLADIV HACLQIDPAE RVSSTDLLNH DYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013