EKS-SAH-00205

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00205

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/CAMKK	441.1	2.0E-132	91	372	282

Status

Unreviewed

Ensembl Protein

ENSSHAP00000019193

UniProt Accession

G3WUT8;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMKK2

Gene Synonyms/Alias

CAMKK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000016296	ENSSHAP00000019193	ENSSHAT00000019349

Organism

Sarcophilus harrisii

Functional Description

Protein Length

443

Protein Sequence
(FASTA)

PQEDALRAPA APGPQARPLL SGRKLSLQER SQAAPSPGGS GGVNGRFIYP SLPYSPVSSP 60

QSSPRLPRRP TVESRHVSIT GMQDCVQLNQ YTLKDEIGKG SYGVVKLAYN EDDNTYYAMK 120

VLSKKKLVRQ AGFPRRPPPR GTKPASEGCI QPKGPIEQVY QEIAILKKLD HPNVVKLVEV 180

LDDPNEDHLY MVFELVNQGP VMEVPTVKPL TEDQARFYFQ DLIKGIEYLH YQKIIHRDIK 240

PSNLLVGEDG HIKIADFGVS NEFKGTDALL TNTVGTPAFM APETLSETRK IFSGKALDVW 300

AMGVTLYCFV FGQCPFMDER ILSLHSKIKS QALEFPDQPD IADDLKDLIV RMLDKNPESR 360

IIVPEIKLHP WVTRHGAEPL PTEDENCTLV EVTEEEVENS VKHIPSLATV ILVKTMIRKR 420

SFGNPFEGSR REERSLSAPG NLL 443

Nucleotide Sequence
(FASTA)

CCGCAGGAGG ACGCTCTCCG GGCCCCCGCG GCCCCCGGGC CCCAGGCCCG GCCCCTCCTC 60

TCTGGCCGCA AGCTGTCCCT GCAGGAGCGC TCGCAGGCCG CCCCCTCCCC GGGCGGCAGC 120

GGGGGCGTCA ACGGCCGCTT CATCTACCCC TCTCTCCCCT ACTCTCCCGT CAGCTCCCCC 180

CAGTCCTCCC CGCGGCTGCC CCGCAGGCCC ACCGTGGAGT CCCGGCACGT CTCCATCACC 240

GGGATGCAGG ATTGTGTACA GCTTAATCAG TATACGCTGA AAGATGAGAT TGGGAAGGGT 300

TCCTATGGAG TGGTCAAGCT GGCTTACAAC GAAGACGACA ATACTTACTA TGCCATGAAG 360

GTGCTTTCCA AAAAGAAGCT GGTGCGGCAG GCGGGCTTTC CACGCCGTCC CCCGCCCCGT 420

GGTACAAAAC CTGCCTCGGA AGGCTGCATC CAGCCCAAGG GCCCTATTGA ACAGGTCTAC 480

CAAGAGATTG CTATTCTCAA AAAGCTGGAC CATCCCAATG TGGTGAAGTT GGTGGAGGTC 540

CTGGATGACC CAAATGAGGA CCATCTGTAC ATGGTGTTTG AACTGGTCAA TCAGGGGCCT 600

GTAATGGAAG TGCCCACAGT CAAGCCACTG ACTGAGGACC AGGCCCGATT CTACTTCCAA 660

GATCTGATCA AAGGCATCGA ATATTTGCAC TACCAGAAGA TCATCCACCG AGACATCAAG 720

CCATCCAACC TCCTGGTCGG AGAGGACGGA CACATCAAGA TCGCTGACTT TGGTGTGAGC 780

AATGAATTCA AGGGCACCGA TGCCCTCCTC ACCAACACTG TGGGCACGCC TGCCTTCATG 840

GCTCCTGAAA CGCTGTCTGA GACACGGAAG ATCTTCTCCG GGAAGGCTCT GGACGTGTGG 900

GCCATGGGAG TGACCCTCTA CTGCTTTGTC TTTGGCCAGT GTCCCTTTAT GGATGAACGG 960

ATCTTGTCTT TGCATAGTAA GATCAAAAGC CAGGCCCTGG AATTCCCCGA CCAGCCAGAT 1020

ATCGCTGACG ATCTGAAGGA CCTGATTGTG CGCATGTTGG ACAAGAACCC TGAGTCCAGG 1080

ATCATCGTCC CAGAAATCAA GCTACACCCC TGGGTCACAA GGCACGGGGC GGAGCCGCTG 1140

CCAACGGAGG ATGAGAACTG CACCTTGGTG GAGGTGACGG AAGAGGAGGT GGAGAACTCC 1200

GTCAAACACA TCCCCAGCCT GGCGACCGTG ATCCTTGTGA AGACGATGAT CCGTAAACGG 1260

TCTTTTGGGA ACCCTTTTGA GGGCAGTCGG CGGGAAGAAC GGTCCTTGTC TGCCCCTGGA 1320

AACCTGCTC 1329

Domain Profile

S: 1     yelleeiGkGqyGvvklaydeeekklvaikilskkkllkqigllkr.kpritke.sggea  58

         y+l++eiGkG+yGvvklay+e++++++a+k+lskkkl++q+g+++r +pr+tk+ s g++

Q: 91    YTLKDEIGKGSYGVVKLAYNEDDNTYYAMKVLSKKKLVRQAGFPRRpPPRGTKPaSEGCI  150

         99********************************************999****9999***

S: 59    kklselekvkkeiailkkldhknvvkLievLddpkeeklylvlelvskGevkwkrddkle  118

         + + ++e+v++eiailkkldh+nvvkL+evLddp+e++ly+v+elv++G+v       +e

Q: 151   QPKGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPV-------ME  203

         ***************************************************.......**

S: 119   ipakkpsvlseeqarkilrdvvlGleYLhsqkiihrDikPsnlLlseegkvkiaDfGvsl  178

         +p++kp  l+e+qar +++d+++G+eYLh+qkiihrDikPsnlL++e+g++kiaDfGvs

Q: 204   VPTVKP--LTEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVS-  260

         ******..***************************************************.

S: 179   asatssaefeesdaelsnktvGtPaflaPe.lsesekefssgkalDiWalGvtlYcllfg  237

               +ef+++da l+n tvGtPaf+aPe lse++k f sgkalD+Wa+GvtlYc++fg

Q: 261   ------NEFKGTDALLTN-TVGTPAFMAPEtLSETRKIF-SGKALDVWAMGVTLYCFVFG  312

         ......**********99.********************.********************

S: 238   klPflddselelyekikneslkfpeekeiledlkdlilklLekdpekrisipdikkhpfv  297

         ++Pf+d+++l+l++kik+++l+fp++++i++dlkdli+++L+k+pe+ri +p+ik+hp+v

Q: 313   QCPFMDERILSLHSKIKSQALEFPDQPDIADDLKDLIVRMLDKNPESRIIVPEIKLHPWV  372

         ***********************************************************8

Domain Sequence
(FASTA)

YTLKDEIGKG SYGVVKLAYN EDDNTYYAMK VLSKKKLVRQ AGFPRRPPPR GTKPASEGCI 60

QPKGPIEQVY QEIAILKKLD HPNVVKLVEV LDDPNEDHLY MVFELVNQGP VMEVPTVKPL 120

TEDQARFYFQ DLIKGIEYLH YQKIIHRDIK PSNLLVGEDG HIKIADFGVS NEFKGTDALL 180

TNTVGTPAFM APETLSETRK IFSGKALDVW AMGVTLYCFV FGQCPFMDER ILSLHSKIKS 240

QALEFPDQPD IADDLKDLIV RMLDKNPESR IIVPEIKLHP WV 282

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013