EPS-SAH-00023

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-SAH-00023

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	211.6	1.8E-62	663	908	246

Status

Unreviewed

Ensembl Protein

ENSSHAP00000019634

UniProt Accession

G3WW29;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP1

Gene Synonyms/Alias

PHLPP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000016669	ENSSHAP00000019634	ENSSHAT00000019791

Organism

Sarcophilus harrisii

Functional Description

Protein Length

1207

Protein Sequence
(FASTA)

MDSEIGCLIR FYAGKPHSTG GSERIQLSGM YNVRKGKMQL PVNRWTKRQV ILCGTCLIVS 60

SVKDSLTGKM HVLPLIGGKV EEVKKHQHCL AFSSSGPQSQ TYYICFDTFT EYLRWLRQVS 120

KVASQRISSV DLSCCSLEHL PANLFYSQDL THLNLKQNFL RQNPSSPASR GLGELKRFTK 180

LKSLNLSNNH LGDFPLAVCN IPTLTELNVS CNALRTVPAT AGDMHKIFIV LLDGNYLQSL 240

PAELENMQQL SYLGLSFNEF TDIPKVLEKL TAVDKLCMSG NCMEMLNLQA LRRMPHIKHV 300

DLRLNIIRKL MVQELDFLPH VTQLDLRDNK LGDLDATVFN NLEVLHCERN QLVTLNVCGY 360

LLKALYASSN ELVQLDIYPV PNHLTFMDVS RNHLESVPEW VCESRKLEVL DIGHNQIREL 420

PARLFYNSSL RKLLVGHNQL TKLPERLERT QVEVLDVQHN QLVELPPNLL MKADSLRFLN 480

ASANKLETIP PATLSEETSS ILQELYLTNN HLTDKCVPLL IGHPHLKILH MAYNRLQSFP 540

ASKMAKLEEL EEIDISGNKL KAIPTTIMNC RRMHTVIAHS NSIEVFPEVM QLTEIKCVDL 600

SCNELSEVTL PENLPSKLQE LDLTGNPRLS LDHKTLELLN NIRCFKIDQP SAGDASGAPA 660

VWSHGYTEAS GVKNKLCVAA LSANNFCDNR EALYGVFDGD RNVEVPYLLQ CTMSDILAEE 720

LQKTKNEEEY MVNTFIVMQR KLGTAGQKLG GSAVLCHIKH DPMDPGGYFT LTSANVGKCQ 780

TVLCRNGKPL PLSKSYIMSC EEELKRIKQH KAIITEDGKV NGVTESTRIL GYTFLHPSVV 840

PRPHVQSVTL TPQDEFFILG SKGLWDSLSI EEAVEAVRNV PDALAAAKKL CTLAQSYGCN 900

DSISAVVVQL NVTEDSFCCC ELTGSGVPPP SPGIFPPSVN VVIKDRPSDG LGVPSSSSGM 960

ASEISSEIST SEMSSEVGST ASDEPPPGAL SESSPAYPSE QRCMLHPVCL SGSFQRQLSS 1020

ATFSSAFSDN GLDSDDEEPI EGVFTNGSRV EVEVDIHCGQ AKEREKQQQL LPQVPTEASD 1080

EGIVISANED EVGLPRKPDF SATGTIGRRR GNGSVAPQER SHNMIEVAAD APLRKTGGYF 1140

AAPAQPDPDD QFIIPPELEE EVKEIMKHHQ EQQQQQQQQQ QQQQQQQQQQ QRQYQMDQLP 1200

DYYDTPL 1207

Nucleotide Sequence
(FASTA)

ATGGATTCCG AGATCGGGTG TCTCATCCGC TTCTATGCAG GAAAGCCCCA TAGCACAGGT 60

GGCTCTGAAC GTATTCAGCT CTCAGGAATG TACAATGTGC GAAAAGGGAA AATGCAGTTA 120

CCAGTGAACC GATGGACAAA ACGCCAAGTT ATTCTGTGTG GAACATGCCT GATTGTATCA 180

TCCGTGAAAG ACAGCTTGAC TGGAAAGATG CACGTTCTCC CACTAATTGG TGGAAAAGTT 240

GAAGAAGTAA AGAAGCACCA GCACTGTTTA GCCTTCAGTT CCTCTGGACC TCAAAGCCAG 300

ACCTATTACA TTTGTTTTGA TACTTTTACT GAGTACTTAA GGTGGCTTCG ACAAGTATCA 360

AAGGTTGCCT CACAGCGTAT CAGCTCAGTG GACCTTTCCT GCTGTAGCCT GGAACATCTC 420

CCTGCCAACC TTTTCTACAG CCAAGACCTC ACTCATCTCA ATTTAAAGCA AAACTTCCTA 480

AGGCAAAATC CCAGCTCACC AGCTAGCAGA GGACTTGGTG AACTCAAAAG GTTTACCAAG 540

TTGAAGAGCC TTAATCTTTC CAATAACCAT CTCGGAGATT TCCCTCTGGC AGTATGCAAT 600

ATCCCAACCT TGACTGAGCT GAATGTGTCC TGCAATGCCC TAAGAACTGT TCCAGCAACA 660

GCAGGAGATA TGCACAAGAT TTTTATTGTT TTGTTGGATG GTAACTATCT TCAGTCCCTT 720

CCTGCTGAGC TGGAGAATAT GCAGCAACTC AGTTACCTAG GACTCTCCTT CAATGAATTC 780

ACAGACATTC CAAAGGTTTT GGAGAAACTG ACTGCTGTCG ATAAACTTTG TATGTCTGGA 840

AATTGTATGG AGATGCTCAA CCTGCAGGCT TTAAGAAGAA TGCCACACAT TAAACATGTG 900

GATTTGAGAT TGAATATAAT TAGGAAGCTG ATGGTGCAGG AGTTAGACTT CCTTCCACAT 960

GTGACTCAAC TTGACTTGCG AGATAATAAA CTTGGTGATC TGGATGCTAC AGTTTTCAAC 1020

AATCTTGAAG TTCTGCACTG TGAAAGGAAC CAGTTGGTGA CACTCAATGT TTGTGGCTAT 1080

TTGCTAAAAG CACTCTATGC TTCTTCAAAT GAACTTGTTC AACTCGATAT TTACCCAGTT 1140

CCAAATCATC TGACATTCAT GGATGTTTCG AGGAACCATC TAGAAAGTGT CCCTGAGTGG 1200

GTATGTGAGA GCCGCAAGCT AGAAGTGTTG GACATTGGTC ATAACCAGAT CCGTGAGCTC 1260

CCTGCACGCT TGTTTTATAA TAGTAGTCTT CGTAAACTGC TGGTAGGCCA TAACCAGCTA 1320

ACCAAGCTAC CAGAAAGACT GGAGAGAACC CAGGTAGAAG TCCTGGATGT TCAGCACAAC 1380

CAGCTTGTTG AGTTACCACC CAATCTCCTG ATGAAGGCTG ACAGCTTGAG GTTCTTAAAT 1440

GCATCTGCCA ACAAGCTGGA AACTATCCCT CCGGCCACGC TTTCAGAAGA GACAAGTAGT 1500

ATCTTGCAGG AGCTGTACCT GACTAACAAC CACCTCACTG ACAAGTGTGT GCCCTTGTTA 1560

ATAGGGCATC CTCACTTGAA GATTCTGCAT ATGGCCTATA ATCGGCTTCA GAGTTTTCCA 1620

GCAAGTAAAA TGGCCAAACT GGAGGAACTG GAAGAAATCG ATATCAGTGG GAACAAATTG 1680

AAAGCCATTC CAACCACTAT CATGAATTGT CGACGAATGC ATACTGTGAT CGCTCACTCT 1740

AACTCCATCG AAGTCTTCCC TGAAGTCATG CAACTAACAG AAATCAAGTG TGTGGACCTG 1800

AGCTGTAATG AACTAAGTGA AGTCACATTA CCTGAAAACC TGCCTTCAAA GCTACAAGAA 1860

CTAGACTTGA CTGGAAACCC TCGGCTTTCC CTGGATCACA AAACTCTGGA GCTGTTGAAT 1920

AATATCCGAT GTTTTAAGAT TGACCAGCCT TCAGCTGGGG ATGCTTCAGG AGCCCCAGCT 1980

GTATGGAGCC ATGGCTACAC TGAAGCCTCA GGTGTAAAGA ATAAGTTATG TGTTGCAGCC 2040

CTGTCAGCAA ATAATTTTTG TGACAACCGG GAGGCTCTAT ATGGAGTCTT TGATGGAGAC 2100

CGCAATGTAG AAGTGCCATA TCTTCTGCAA TGCACAATGA GTGACATTCT GGCAGAGGAA 2160

CTACAGAAAA CAAAAAATGA AGAGGAGTAC ATGGTCAACA CTTTCATTGT CATGCAAAGG 2220

AAACTTGGAA CTGCTGGGCA AAAACTTGGA GGCTCTGCTG TCCTGTGCCA TATAAAGCAT 2280

GATCCTATGG ACCCAGGAGG ATATTTCACC TTGACCTCTG CTAATGTGGG AAAATGCCAA 2340

ACAGTTCTGT GCCGGAATGG GAAACCTTTG CCTCTGTCGA AATCTTATAT CATGAGCTGT 2400

GAAGAGGAAT TGAAGAGAAT CAAGCAGCAT AAAGCCATTA TCACTGAGGA TGGCAAGGTG 2460

AATGGAGTAA CTGAGTCTAC ACGGATCTTG GGCTACACTT TCCTGCACCC CAGCGTGGTT 2520

CCCCGTCCTC ACGTGCAGTC GGTGACACTG ACCCCACAAG ACGAGTTCTT CATCTTGGGC 2580

AGCAAGGGGC TGTGGGACAG CCTGTCCATC GAGGAGGCAG TGGAGGCCGT GCGGAACGTG 2640

CCCGACGCTT TAGCCGCGGC CAAGAAGCTG TGCACACTGG CCCAGAGTTA CGGCTGTAAC 2700

GACAGCATCA GCGCTGTGGT GGTGCAGCTC AATGTCACCG AGGACAGCTT CTGCTGCTGT 2760

GAGCTCACCG GAAGTGGGGT CCCCCCTCCA AGCCCAGGCA TCTTTCCTCC CTCGGTCAAT 2820

GTGGTGATCA AAGACCGGCC CTCCGACGGG CTGGGAGTGC CCTCCTCCAG CAGTGGCATG 2880

GCCTCTGAGA TCAGCAGTGA GATCTCCACC TCGGAGATGA GCAGCGAGGT GGGCTCCACA 2940

GCCTCGGACG AGCCCCCCCC GGGAGCCCTG AGTGAGAGCA GCCCGGCCTA CCCCAGCGAG 3000

CAGCGCTGCA TGCTCCACCC CGTCTGTCTG TCAGGCTCTT TCCAGAGACA GCTCTCCAGC 3060

GCCACCTTCT CCAGTGCCTT CTCCGACAAC GGCCTGGACA GTGATGATGA AGAGCCCATC 3120

GAAGGGGTCT TCACCAATGG CAGCAGGGTG GAGGTGGAGG TGGACATTCA CTGTGGCCAG 3180

GCCAAGGAGA GGGAGAAGCA GCAGCAGCTA CTGCCTCAGG TACCCACCGA GGCCAGCGAC 3240

GAGGGCATTG TGATCAGTGC CAATGAGGAC GAGGTGGGGC TGCCCAGGAA GCCCGACTTC 3300

TCTGCTACCG GGACCATTGG GCGCAGGAGA GGCAACGGCT CTGTGGCCCC CCAGGAGAGG 3360

AGCCACAACA TGATTGAGGT GGCTGCCGAT GCCCCTCTCC GGAAAACGGG GGGCTACTTT 3420

GCAGCTCCGG CTCAGCCTGA TCCCGATGAC CAGTTTATCA TCCCACCTGA GCTAGAAGAG 3480

GAAGTCAAAG AAATCATGAA ACATCATCAG GAGCAGCAAC AGCAGCAGCA GCAGCAGCAG 3540

CAGCAACAAC AGCAGCAGCA GCAGCAGCAG CAGCGGCAGT ATCAGATGGA CCAACTGCCA 3600

GACTATTATG ATACACCACT ATGA 3624

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 663   SHGYTEASGVKNKLCVAALSANNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  717

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 718   AEELQ----KTKNEEEYMVNTFIVMQRKL------GTAGQKLGGSAVLCHIKHDpmdpgg  767

         ***99....999*****************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ + +s+e+El+Ri+++++ ++++   +v+Gv++

Q: 768   yfTLTSANVGKCQTVLCRNGKPLPLSKSYIMSCEEELKRIKQHKAIITEDG--KVNGVTE  825

         ********************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s++lt++def+iL+s+Glwd +s eeav++vr+v +

Q: 826   STRILGYTFLHPSVVPRPHVQSVTLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPD---  882

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL++la+++g++d++sa+vv

Q: 883   -ALAAAKKLCTLAQSYGCNDSISAVVV  908

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS ANNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKNEEEYMV NTFIVMQRKL GTAGQKLGGS AVLCHIKHDP MDPGGYFTLT SANVGKCQTV 120

LCRNGKPLPL SKSYIMSCEE ELKRIKQHKA IITEDGKVNG VTESTRILGY TFLHPSVVPR 180

PHVQSVTLTP QDEFFILGSK GLWDSLSIEE AVEAVRNVPD ALAAAKKLCT LAQSYGCNDS 240

ISAVVV 246

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>