EKS-SAH-00087

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SAH-00087

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	399.0	1.9E-119	2099	2420	322

Status

Unreviewed

Ensembl Protein

ENSSHAP00000020488

UniProt Accession

G3WYI3;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSHAG00000017370	ENSSHAP00000020488	ENSSHAT00000020651

Organism

Sarcophilus harrisii

Functional Description

Protein Length

3638

Protein Sequence
(FASTA)

MRFLRTDSAS ADPDNLKYSS SRDRGSSASY GLQPSNSAVV SRQRHDDIRV HTDIQNDEKG 60

GYSVNGGSGE NTYGRKSLGQ ELRVNNVTNP DFTSIQHGNR ALATKDMRKS QERSLSYSDE 120

SRLSNLLRRI TREDDRDRRL ATVKQLKEFI QQPENKLVLV KQLDNILAAI HDVLNESSKL 180

LQELRQEGAY SLGLLCASLS YEAEKIFKWI FSKFSSSAKD EVKLLYLCAT YKALETVGEK 240

KAFSSVMQLV MTSLQSILEN VDTPELLCKC VKCILLVARC YPHIFSTNFR DTVDILVGWH 300

IDHTQKPSLT QQVSGWLQSL EPFWVADLAF STTLLGQFLE DMEAYAEDLS HVASGESVDE 360

DIPPPSVSLP KLAALLRVFS TVVRSIGERF SPIRGPPITE AYVTDVLYRV MRCVTAANQV 420

FFSEAVLTAA NECVGVLLGS LDPSMTIHCD MVITYGLDQL ENCQTCGTDY IISVLNLLTL 480

IVEQINTKLP SSFVEKLFIP ASKLLLLRYH KEKEVVAVAH AVYQAVLSLK NIPVLETAYR 540

LILGEMTCAL NNLLHNLQLP EACSEIQHDA FKNHVFNVDN AKFVVIFDLS ALTTIGNAKN 600

SLIGMWALSP TVFALLSKNL MIVHGDLAVH FPAIQYAVLY TLYSHCTRHD HFISSSLSSS 660

SPSLFDGAVI STVTTATKKH FSIILNLLGI LLKKDNLNQD TRKLLMTWAL EVAVLMKKSE 720

TYAPLFSLPS FHKFCKGLLA NTLLEDVNIC LQACSSLHAL SSSLPDDLLQ RHRCVDVCRV 780

QLVHSGTRIR QAFGKLLKSI PLDVVLSNSN HTEIQEISLA IRSHMSKAPS NTFHPQDFSD 840

VISFILYGNS HRTGKDNWLE RLFYSCQRLD KRDQSTIPRN LLKTDAVLWQ WAIWEAAQFT 900

VLSKLRTPLG RAQDTFQTIE GIIRSLAAHT LNPDQDVSQW TTADNDEGHS SNQLRLVLLL 960

QYLENLEKLM YNAYEGCANA LTSPPKVIRT FFYTNRQTCQ DWLTRIRLSI MRVGLLAGQP 1020

AVTVRHGFDL LTEMKANNVS QGNELEVTIM MVVEALCELH CPEAIQGLAV WSSSVVGKNL 1080

VWINSVAQQA EGRFEKATIE YQEHLCAMTG VDCSITGFDK SVLKLANSNS NNASPKHSLN 1140

GEGRKTVLAK PSDSSPEVIN YLGNKACECY ISIADWAAVQ EWQNAVHDLK KSTSSTSLNL 1200

KADFNYIKSL SSFESGEFIE CTEQLELLPG ENINLLTGGS KEKIDMKKLL PNMLSPDPRE 1260

LQKSIEVQLL RSSVCLATAV NHIEQEQKWQ SITENVVKYL KQTSRIAIGP LRLSTLTVSQ 1320

SLPVLSTLQL YCSSALENTV SNRLSTEDCL IPLFSEALRS CKQHDVRPWM HALRYTVYQS 1380

QLLEKIKEQT VPIRSHLMEL GLTAAKFARK RGNVALATRL LAQCSEVQLG KTTTAQDLVQ 1440

YFKKLSTQSQ VDEKWGPELD IEKTKLLYTA GQSTHAMEML SSCAIAFCKS AKAEYAVAKS 1500

ILTLAKWIQA EWKEISGQLK QVYRAQQQQN FSGLSTLSKN IHTLIALPSV NAIEEEYPRI 1560

ESESTVNIGV GEPDFILGQL YHLSSVQAPE VAKSWAALAS WAYRWGRKVV DNASQGEGVR 1620

LLPREKSEVQ NILPDTITEE DKEKIYGILG QAVCRPAGIQ DEDITLQITE SEDNEEDDMV 1680

DVIWRQLLAS CSWLSDLDEN ATEGLIKVWR KVVDRIFSLY KLSCSAYFTF LKLNAGQIPL 1740

DEDDPRLHLS NRSEQSTDDV IVMATLRLLR LLVKHAGELR QYLEHGLETT PTAPWRGIIP 1800

QLFSRLNHPE VYVRQSICNL LCRVAQDSPH LILYPAIVGT ISLSTESQSS GNKLPSAIPT 1860

LLGNIQGEEL LGAECEGGSP PASQDSNKDE PKNGLNEDQA MMQDCYSKIV DKLSSANPTM 1920

VLQVQMLVAE LRRVTVLWDE LWLGVLLQQH MYVLRRIQQL EDEVKRVQNN NTLRKEEKIA 1980

IMREKHTALM KPIVFALEHV RSITAAPAET PHEKWFQDNY GDAIENALEK LKNPSNPAKP 2040

GSSWIPFKEV MLSLQQRAQK RASYILRLEE ISPWLAAMTN TEIALPGEVS ARDTVTIHSV 2100

GGTITILPTK TKPKKLLFLG SDGKNYPYLF KVGLEDLHLD ERIMQFLSIV NTMFATINRQ 2160

ETPRFHARHY SVTPLGTRSG LIQWVDGATP LFGLYKRWQQ REAALQAQKA QDSYQTPQNP 2220

GIVPRPSELY YSKIGPALKA VGLSLDVSRR DWPLNVMKAV LEELMEATPP NLLAKELWSS 2280

CTTPDEWWRV TQSYARSTAV MSMVGYIIGL GDRHLDNVLI DMTTGEVVHI DYNVCFEKGK 2340

SLRVPEKVPF RMTHNIETAL GVTGVEGVFR LSCEQVLHIM RRGRETLLTL LEAFVYDPLV 2400

DWTAGGEAGF AGAVYGGGGQ QAENKQSKRE MERDITRSLF SSRVAEIKVN WFKNRDEMLI 2460

VLPKLDSSLE EYLNLQEQLT DVEKLQGKLL EEIEFLEGAE GAEHPSHTLQ HRYSEHTQLQ 2520

TQQRAVQEAI QVKLNEFEQW ITHYQAAFSN LEATQLASLL QEISTQMDLG PPSYVPATAF 2580

LQNAGQAHLI SQCEQLEGEV GALLQQRRSV LRGCLEQLHH YATVALQYPK AIFQKHRIEQ 2640

WKTWMEELIC NTTIERCQEL YRKYEMQYAP QPPPTVCQFI TATEMTLQRY AADINSRLIR 2700

QVERLKQEAV TVPVCEEQLK EIERCIKVFL HENGEEGSLS LASVIISALC TLTRRNLMME 2760

GAASSAGEQL VDLTSRDGAW FLEELCSMSG NVTCLVQLLK QCHLVPQDLD IPNPMEASEA 2820

VHLANGVYTS LQELNSNFRQ IIFPEALRCL MKGEYTLESM LHELDTLIEQ TTDGVPLQTL 2880

VESLQAYLRN AAMGLEEETH AHYIDVARIL HAQYGELIQP RNGSVDETPK MSAGQMLLVA 2940

FDGMFAQVET AFGLLIEKLN KMEIPVAWRK IDIIREARST QVNFFDDDNH RQVLEEIFFL 3000

KRLQTIKEFF RLCGTFSKTL SGSSSLEDQN TVNGPVQIVN VKTLFRNSCF SEDQMAKPIK 3060

AFTADFVRQL LIGLPNQALG LTLCSFISAL GVDIIAQVEA KDFGAESKVS VDDLCKKAVE 3120

HNIQIGKFSQ LVMNRATVLA SSYDTAWKKH DLVRRLETSI SSCKTSLQRV QLHIAMFQWQ 3180

HEDLLISRPQ AMSVTPPPRS AILTSMKKKL HTLSQIETSI AAVQEKLAAL EASIEQRLKW 3240

AGGANPALAP VLQDFEATIA ERRNLVLKES QRASQVTFLC SNIIHFESLR TRTAEALNLD 3300

ASLFELIKRC QQMCSFASQF NSSVSELELR LLQRVGTNLE HAIGSSEWLL SAHKQLSQDM 3360

STQRVVQTEK EQQIETVCET IQNLVDNIKT VLTGHNRQLG DVKHLLKAMA KDEEAALADG 3420

DDVPYENSVR QFLGEYKSWQ DNIQTVLFTL VQAMGQVRSQ EHVEMLQEIT PTLKELKTQS 3480

QSIYNNLVSF ASPLVTDATN ECSSPTSSAT YQPTFAAAVR SNTGQKTQPE VMSQNARKAI 3540

QKNLATSADT PPSTVPGTGK SVACSPKKAV RDPKTGKAVQ ERNSYAVSVW KRVKAKLEGR 3600

DVDPNRRMSV AEQVDYVIKE ATNLDNLAQL YEGWTAWV 3638

Nucleotide Sequence
(FASTA)

ATGCGATTTT TGAGAACTGA TAGTGCATCA GCCGACCCAG ATAATTTAAA ATACTCTTCA 60

TCCAGAGATC GAGGCAGTTC TGCCTCATAT GGACTGCAAC CTTCAAATTC AGCTGTGGTG 120

TCTCGTCAAA GGCACGATGA TATCAGAGTC CATACTGACA TACAAAATGA CGAAAAAGGT 180

GGCTACAGTG TCAATGGAGG ATCTGGGGAA AATACTTATG GTCGGAAGTC GTTGGGGCAA 240

GAGCTGAGAG TTAACAATGT GACCAACCCT GATTTCACCA GTATTCAGCA TGGAAATCGT 300

GCTTTAGCCA CAAAAGACAT GAGGAAATCA CAGGAGCGAT CGTTGTCTTA CTCTGATGAG 360

TCTCGACTGT CAAATCTTCT TCGGAGGATT ACCCGGGAAG ATGACAGAGA CCGAAGACTG 420

GCTACTGTAA AGCAATTGAA AGAATTCATT CAGCAACCAG AAAATAAACT GGTACTAGTT 480

AAGCAGCTAG ATAATATCTT GGCAGCTATA CATGATGTGC TTAATGAGAG TAGCAAATTG 540

CTTCAAGAAT TGAGACAGGA GGGAGCTTAC TCTCTTGGCC TTCTTTGTGC TTCCCTAAGC 600

TATGAGGCTG AGAAAATCTT CAAATGGATT TTTAGCAAAT TTAGCTCATC TGCAAAAGAT 660

GAAGTTAAAC TTCTTTACTT ATGTGCCACC TACAAAGCAC TAGAGACTGT AGGAGAAAAG 720

AAGGCTTTTT CATCTGTAAT GCAGCTTGTG ATGACCAGCC TACAGTCCAT TCTAGAAAAT 780

GTGGATACAC CAGAATTACT CTGCAAATGT GTGAAGTGCA TACTTTTGGT GGCTCGATGT 840

TACCCTCATA TTTTCAGCAC AAATTTTAGG GATACGGTTG ATATATTAGT TGGATGGCAT 900

ATAGATCACA CTCAGAAACC TTCTCTGACT CAGCAGGTGT CTGGATGGTT ACAGAGTCTG 960

GAGCCATTTT GGGTAGCTGA TCTTGCATTT TCTACTACTC TTCTTGGTCA GTTTCTAGAA 1020

GATATGGAAG CTTATGCTGA GGACCTCAGT CACGTAGCCT CTGGGGAGTC AGTAGATGAA 1080

GATATTCCTC CTCCATCGGT ATCATTACCA AAGTTAGCAG CACTACTTCG TGTATTCAGT 1140

ACTGTGGTAA GAAGCATTGG GGAGCGTTTC AGCCCAATCA GAGGTCCTCC AATTACTGAA 1200

GCGTATGTCA CAGATGTACT GTACAGAGTA ATGAGATGCG TTACAGCAGC AAACCAAGTA 1260

TTTTTTTCTG AGGCAGTTTT GACTGCTGCC AATGAATGTG TTGGTGTTTT GCTTGGTAGC 1320

TTAGACCCTA GCATGACTAT ACATTGTGAC ATGGTCATCA CATATGGATT AGATCAGTTG 1380

GAGAATTGCC AGACTTGTGG TACAGATTAT ATCATCTCGG TCTTGAATTT GCTCACATTG 1440

ATTGTTGAAC AGATAAATAC AAAATTACCA TCATCATTCG TAGAAAAACT GTTTATACCG 1500

GCATCTAAAC TACTACTTCT GCGTTATCAT AAAGAAAAAG AGGTTGTTGC TGTAGCTCAT 1560

GCCGTATATC AAGCTGTACT CAGCCTGAAG AATATTCCTG TTTTGGAGAC TGCCTACAGG 1620

TTAATTTTGG GAGAAATGAC CTGTGCACTG AACAATCTCC TGCATAACCT ACAACTGCCT 1680

GAAGCCTGTT CTGAAATCCA ACATGATGCT TTTAAGAACC ATGTATTCAA TGTAGACAAT 1740

GCAAAATTTG TAGTTATATT TGACCTCAGT GCATTAACCA CAATTGGAAA TGCCAAAAAC 1800

TCATTGATTG GGATGTGGGC GCTGTCTCCA ACGGTCTTTG CACTCCTGAG TAAGAACCTA 1860

ATGATTGTGC ATGGTGACTT AGCTGTCCAT TTCCCGGCTA TTCAATATGC AGTCCTCTAT 1920

ACCTTATATT CACATTGTAC CAGGCATGAT CACTTTATAT CTAGTAGCCT TAGTTCTTCA 1980

TCCCCATCAC TGTTTGATGG AGCCGTAATT AGTACTGTAA CAACAGCCAC AAAGAAGCAT 2040

TTCTCAATCA TACTCAACCT CTTGGGAATA TTGCTAAAGA AAGATAACCT TAATCAGGAT 2100

ACCAGGAAAC TGCTAATGAC TTGGGCTTTG GAAGTTGCTG TTCTAATGAA AAAGTCTGAA 2160

ACATATGCAC CTTTATTCTC TCTTCCATCT TTCCATAAGT TTTGCAAAGG ACTTCTAGCA 2220

AACACCCTTC TTGAAGACGT GAATATTTGT CTTCAGGCAT GTAGTAGCCT ACATGCCCTG 2280

TCATCTTCCT TGCCTGATGA TCTTTTACAA AGACATAGGT GTGTTGATGT ATGTCGTGTC 2340

CAGCTGGTCC ATAGTGGGAC TCGTATTCGG CAAGCCTTTG GAAAGTTGTT GAAATCTATT 2400

CCTTTGGATG TTGTCCTGAG CAATAGCAAC CACACAGAAA TACAAGAAAT TTCTTTAGCT 2460

ATAAGAAGTC ATATGAGCAA AGCTCCAAGT AACACGTTCC ATCCACAAGA TTTCTCTGAT 2520

GTCATTAGTT TTATTTTGTA TGGGAATTCT CATAGAACTG GGAAGGACAA TTGGTTAGAG 2580

AGATTGTTCT ACAGTTGCCA GAGGCTAGAT AAGCGTGACC AATCAACTAT TCCACGAAAT 2640

CTTCTAAAGA CAGATGCTGT TCTTTGGCAG TGGGCTATTT GGGAAGCGGC CCAGTTCACT 2700

GTTCTTTCTA AGTTAAGAAC CCCCCTAGGC AGAGCACAAG ATACATTCCA GACAATTGAA 2760

GGAATCATCA GGAGTCTTGC AGCCCACACA TTAAACCCCG ATCAAGATGT CAGCCAATGG 2820

ACAACTGCAG ACAATGATGA AGGACATAGC AGCAATCAAC TTAGACTTGT TCTTCTTCTG 2880

CAATACTTAG AAAATCTGGA AAAGTTAATG TATAATGCAT ACGAAGGATG TGCTAATGCA 2940

CTGACTTCAC CTCCTAAGGT CATTAGGACA TTTTTCTATA CCAATCGCCA AACTTGTCAA 3000

GACTGGTTAA CTCGGATTAG ACTTTCCATC ATGAGAGTTG GACTGTTGGC AGGTCAACCT 3060

GCTGTGACTG TAAGGCATGG CTTTGATTTG CTTACTGAAA TGAAGGCTAA TAATGTATCT 3120

CAGGGAAATG AATTGGAAGT AACAATTATG ATGGTAGTAG AAGCACTGTG TGAGCTACAT 3180

TGCCCTGAAG CTATACAAGG ACTAGCTGTA TGGTCATCTT CAGTTGTTGG GAAGAATCTT 3240

GTCTGGATTA ATTCAGTTGC ACAACAGGCA GAAGGAAGGT TCGAAAAGGC AACCATTGAA 3300

TACCAGGAGC ACTTGTGTGC CATGACAGGT GTAGATTGCA GCATAACTGG GTTTGATAAA 3360

TCTGTCTTGA AGTTGGCCAA CTCTAATAGT AATAATGCCA GTCCAAAACA TTCTCTGAAT 3420

GGTGAAGGTA GAAAAACTGT CCTGGCAAAA CCAAGTGATT CTTCCCCTGA AGTTATAAAT 3480

TATTTGGGTA ATAAAGCATG TGAGTGTTAC ATCTCAATTG CTGATTGGGC TGCAGTACAG 3540

GAATGGCAGA ATGCTGTCCA TGACTTGAAA AAAAGTACAA GTAGTACTTC ACTCAACTTA 3600

AAAGCTGACT TCAACTACAT AAAGTCACTA AGCAGCTTTG AGTCTGGAGA ATTTATTGAA 3660

TGTACTGAAC AGTTAGAATT ATTACCAGGA GAAAACATTA ACCTACTTAC TGGAGGATCA 3720

AAAGAAAAAA TAGATATGAA AAAACTCCTT CCTAACATGT TAAGTCCAGA CCCGAGGGAA 3780

CTTCAGAAAT CCATTGAAGT TCAGTTGTTG AGAAGTTCAG TTTGTTTGGC AACTGCTGTA 3840

AATCATATAG AACAGGAACA GAAGTGGCAG TCTATAACTG AAAATGTTGT AAAATATTTG 3900

AAACAAACAT CACGTATAGC TATTGGACCC CTGAGGCTCT CTACGCTAAC TGTTTCACAG 3960

TCTTTGCCAG TGTTAAGTAC TCTACAACTT TATTGTTCAT CTGCTTTGGA GAATACTGTG 4020

TCAAACAGGC TTTCAACAGA GGACTGTTTA ATCCCACTTT TTAGTGAAGC TTTGCGTTCA 4080

TGTAAACAAC ATGATGTACG ACCATGGATG CATGCACTAA GATATACTGT ATATCAGAGT 4140

CAGTTACTTG AAAAAATAAA AGAGCAAACT GTACCAATTA GGAGTCACCT TATGGAACTA 4200

GGTCTAACAG CAGCAAAATT TGCCAGAAAA CGGGGAAACG TAGCCCTTGC CACCAGATTG 4260

CTTGCACAGT GTAGTGAAGT CCAATTGGGG AAAACTACTA CTGCTCAAGA TTTAGTTCAG 4320

TATTTTAAAA AACTGTCAAC ACAAAGCCAG GTAGATGAAA AATGGGGACC TGAGCTTGAT 4380

ATAGAAAAAA CCAAACTGTT ATATACAGCA GGTCAGTCAA CACATGCCAT GGAAATGTTG 4440

AGTTCTTGTG CCATAGCCTT TTGCAAGTCT GCCAAAGCAG AATATGCAGT AGCCAAATCA 4500

ATTCTGACTT TGGCTAAATG GATTCAAGCA GAATGGAAGG AAATTTCGGG GCAGTTGAAA 4560

CAGGTATACA GAGCCCAACA GCAACAGAAT TTCTCTGGTC TTTCTACTTT GTCTAAAAAC 4620

ATACATACTT TAATTGCTCT ACCATCTGTC AATGCAATAG AAGAGGAGTA TCCCCGGATT 4680

GAAAGTGAAT CTACAGTAAA TATTGGAGTT GGAGAACCTG ACTTCATATT GGGGCAGTTG 4740

TATCACCTCT CTTCAGTCCA GGCACCTGAA GTTGCCAAAT CTTGGGCAGC ACTGGCTAGT 4800

TGGGCATACA GATGGGGCAG AAAGGTGGTT GATAATGCCA GTCAAGGAGA AGGGGTCCGT 4860

CTACTACCCA GAGAGAAGTC TGAGGTGCAG AATATACTTC CTGATACCAT AACTGAAGAA 4920

GATAAAGAAA AAATATATGG TATTCTTGGT CAGGCTGTAT GCCGACCAGC TGGAATTCAG 4980

GATGAAGATA TAACGCTGCA GATAACAGAA AGTGAAGACA ATGAAGAAGA TGATATGGTT 5040

GATGTCATCT GGCGCCAATT ATTGGCAAGC TGTTCATGGC TTTCAGATCT CGATGAAAAT 5100

GCAACAGAAG GATTAATTAA AGTGTGGCGA AAAGTTGTAG ATAGAATCTT TAGCCTCTAC 5160

AAATTGTCAT GTAGTGCTTA TTTTACTTTT CTTAAACTCA ATGCTGGACA GATTCCTCTA 5220

GATGAAGATG ATCCCAGATT GCATTTAAGT AATAGATCTG AACAGAGTAC TGATGATGTT 5280

ATTGTAATGG CAACTTTAAG GTTATTGAGA TTGCTTGTTA AACATGCTGG AGAACTTAGA 5340

CAATATCTGG AACATGGCTT GGAAACAACA CCCACTGCTC CTTGGAGAGG TATTATTCCA 5400

CAGCTTTTCT CTCGTTTAAA CCACCCTGAA GTATATGTTC GCCAAAGTAT TTGTAATCTA 5460

CTCTGTCGAG TTGCTCAAGA TTCCCCTCAC CTTATATTGT ATCCTGCAAT AGTGGGTACT 5520

ATTTCACTTA GTACTGAATC CCAGTCTTCA GGGAATAAAC TTCCTTCTGC AATTCCTACT 5580

TTGCTGGGTA ATATTCAAGG TGAAGAATTA TTAGGTGCTG AATGTGAGGG AGGAAGTCCC 5640

CCAGCTTCTC AAGATAGTAA TAAGGATGAG CCTAAAAATG GCTTAAATGA AGACCAAGCT 5700

ATGATGCAAG ATTGCTACAG CAAAATTGTA GATAAGCTGT CTTCAGCGAA CCCAACAATG 5760

GTGTTACAGG TCCAAATGCT AGTAGCCGAG CTTCGCAGGG TTACTGTTCT TTGGGATGAG 5820

CTTTGGTTAG GAGTTCTACT GCAACAGCAC ATGTATGTTT TGAGACGGAT TCAACAACTA 5880

GAGGATGAAG TGAAGAGAGT CCAAAACAAC AACACCTTAC GCAAAGAGGA AAAAATTGCT 5940

ATCATGCGTG AGAAGCATAC TGCTTTGATG AAACCCATTG TATTTGCATT GGAACATGTG 6000

CGGAGCATCA CAGCAGCTCC TGCAGAAACT CCTCATGAAA AATGGTTTCA GGACAATTAT 6060

GGTGATGCAA TTGAAAATGC CCTAGAAAAA TTGAAGAATC CATCAAATCC TGCAAAGCCA 6120

GGAAGCAGCT GGATCCCTTT TAAAGAGGTG ATGCTAAGTT TACAGCAGAG AGCACAAAAA 6180

CGTGCTAGTT ACATCTTACG TCTTGAAGAA ATTAGTCCTT GGTTGGCTGC TATGACGAAC 6240

ACTGAAATTG CCCTTCCTGG AGAAGTGTCC GCCAGAGATA CAGTTACAAT TCACAGTGTT 6300

GGTGGTACCA TCACAATCTT GCCTACTAAA ACCAAACCAA AGAAACTTCT CTTTCTAGGT 6360

TCAGATGGGA AGAACTATCC TTATCTTTTT AAAGTAGGAT TGGAAGATTT GCACTTAGAT 6420

GAGAGAATTA TGCAATTCTT GTCTATTGTG AATACTATGT TTGCTACAAT TAATCGTCAA 6480

GAGACACCTC GTTTCCATGC TAGACATTAT TCTGTAACAC CACTAGGAAC CAGATCAGGT 6540

CTCATCCAGT GGGTGGATGG AGCCACACCT TTATTTGGTC TTTACAAACG ATGGCAACAA 6600

AGAGAAGCTG CTTTACAAGC ACAAAAGGCT CAAGATTCTT ATCAAACTCC TCAAAATCCT 6660

GGAATAGTAC CTCGACCAAG TGAACTTTAT TACAGTAAAA TTGGACCTGC CTTAAAAGCA 6720

GTTGGGCTTA GTCTTGATGT CTCTCGTCGT GATTGGCCTC TTAATGTGAT GAAGGCTGTG 6780

TTAGAAGAGC TAATGGAGGC AACACCACCA AATCTTCTGG CTAAGGAACT TTGGTCATCT 6840

TGTACAACTC CTGATGAATG GTGGAGAGTT ACACAGTCAT ATGCAAGATC TACCGCCGTC 6900

ATGTCTATGG TTGGATACAT AATTGGCCTT GGAGATAGAC ATCTGGATAA TGTCCTTATA 6960

GACATGACTA CAGGAGAAGT TGTTCACATA GATTATAACG TTTGCTTTGA AAAAGGTAAA 7020

AGCCTTCGAG TTCCTGAAAA AGTACCTTTC CGTATGACAC ACAATATTGA AACAGCCCTG 7080

GGTGTGACTG GAGTAGAAGG AGTTTTCAGG CTTTCTTGTG AGCAGGTTCT GCATATCATG 7140

CGACGTGGAA GGGAGACTTT GCTTACGTTA CTGGAAGCAT TTGTGTATGA TCCCCTGGTG 7200

GACTGGACAG CTGGGGGAGA AGCAGGATTT GCAGGAGCTG TCTATGGTGG TGGTGGCCAA 7260

CAAGCTGAAA ACAAACAAAG TAAAAGAGAG ATGGAGAGGG ACATTACACG AAGCCTTTTC 7320

TCTTCCAGAG TAGCTGAAAT TAAGGTAAAC TGGTTTAAGA ATAGGGATGA AATGCTGATT 7380

GTACTTCCGA AGCTAGATAG CAGCTTAGAA GAATATCTGA ACTTGCAAGA ACAGCTGACA 7440

GATGTTGAAA AATTACAAGG CAAGCTTCTT GAAGAGATTG AATTCTTAGA AGGAGCAGAA 7500

GGAGCTGAAC ATCCTTCTCA CACACTGCAG CACAGGTATT CTGAACATAC ACAACTGCAA 7560

ACTCAGCAAA GAGCTGTTCA GGAAGCAATC CAGGTGAAAC TAAATGAATT TGAACAGTGG 7620

ATAACACATT ACCAAGCTGC ATTTAGTAAT TTAGAAGCAA CACAACTTGC AAGTCTTCTT 7680

CAAGAGATTA GCACACAAAT GGATCTTGGT CCTCCAAGCT ATGTACCAGC AACAGCTTTT 7740

CTTCAGAATG CTGGTCAAGC TCATTTGATC AGCCAGTGTG AACAGTTAGA AGGAGAAGTT 7800

GGTGCTCTTT TGCAACAGAG GCGGTCAGTA TTAAGAGGAT GTCTTGAGCA GCTGCATCAC 7860

TATGCAACTG TAGCTCTTCA ATACCCAAAA GCAATATTTC AGAAACATCG AATTGAGCAG 7920

TGGAAGACTT GGATGGAAGA ACTTATCTGT AACACGACAA TTGAGCGTTG TCAGGAATTA 7980

TATAGAAAAT ATGAAATGCA GTATGCTCCC CAACCACCTC CAACAGTATG CCAATTCATA 8040

ACTGCCACAG AAATGACTCT TCAGCGTTAT GCTGCAGATA TAAATAGTCG ACTTATCCGA 8100

CAAGTGGAAA GGTTGAAACA AGAAGCTGTT ACTGTGCCAG TTTGTGAAGA ACAATTGAAA 8160

GAAATTGAAC GTTGTATTAA AGTTTTTCTA CATGAAAACG GAGAAGAAGG ATCTTTGAGC 8220

CTAGCTAGTG TTATTATTTC TGCCCTTTGC ACCCTTACAA GGCGTAATCT AATGATGGAA 8280

GGTGCTGCAT CTAGTGCTGG AGAACAACTT GTTGATCTTA CTTCACGGGA TGGAGCCTGG 8340

TTCTTAGAGG AACTATGCAG TATGAGTGGA AATGTTACAT GTCTTGTTCA GTTATTGAAG 8400

CAGTGCCACC TGGTCCCACA GGACTTAGAT ATTCCTAACC CAATGGAGGC ATCTGAGGCA 8460

GTTCACTTAG CTAATGGAGT ATATACTTCA CTTCAGGAAT TGAATTCCAA CTTTCGGCAA 8520

ATAATATTTC CAGAAGCACT TAGATGTTTA ATGAAAGGAG AATATACATT AGAAAGTATG 8580

CTTCATGAAC TGGACACTCT TATTGAACAA ACAACTGATG GAGTTCCTTT ACAGACATTA 8640

GTTGAGTCTC TTCAAGCCTA TTTAAGAAAT GCAGCTATGG GGTTAGAAGA AGAAACACAT 8700

GCTCATTATA TAGATGTTGC AAGAATACTG CATGCTCAGT ATGGTGAATT GATTCAACCC 8760

AGAAATGGTT CAGTTGATGA AACTCCCAAA ATGTCAGCTG GTCAAATGCT TTTAGTTGCT 8820

TTTGATGGAA TGTTTGCCCA AGTTGAAACT GCTTTTGGCT TATTAATTGA AAAGTTAAAT 8880

AAGATGGAAA TACCTGTAGC TTGGCGCAAG ATTGACATTA TAAGGGAAGC CAGGAGTACA 8940

CAAGTTAATT TTTTTGATGA CGATAACCAC CGGCAAGTGT TAGAAGAAAT TTTCTTTTTA 9000

AAACGATTGC AAACAATTAA GGAATTCTTC AGACTCTGTG GTACTTTTTC AAAAACATTG 9060

TCAGGGTCAA GTTCACTTGA AGACCAGAAT ACTGTAAATG GACCTGTACA GATTGTCAAT 9120

GTAAAAACAC TTTTTAGAAA TTCTTGTTTT AGTGAAGACC AAATGGCAAA GCCCATAAAG 9180

GCATTTACAG CAGACTTTGT GAGACAGTTA TTAATTGGAC TCCCAAATCA GGCCTTGGGG 9240

CTTACCCTTT GTAGTTTCAT CAGTGCATTA GGTGTAGACA TAATCGCTCA AGTAGAAGCA 9300

AAAGACTTTG GCGCTGAAAG CAAAGTTTCA GTTGATGATT TGTGTAAGAA AGCAGTGGAA 9360

CATAATATCC AAATTGGAAA GTTTTCTCAG CTGGTCATGA ACAGGGCAAC AGTACTAGCC 9420

AGTTCCTATG ATACTGCTTG GAAGAAACAT GACTTGGTTC GAAGACTAGA AACCAGTATT 9480

TCATCTTGTA AGACAAGCCT CCAGAGAGTA CAACTGCATA TTGCCATGTT TCAGTGGCAG 9540

CATGAAGATC TCCTTATTAG TAGACCACAG GCCATGTCAG TTACACCTCC ACCTCGTTCT 9600

GCTATTTTAA CTAGCATGAA AAAGAAACTT CATACACTGA GTCAGATTGA AACTTCAATT 9660

GCAGCCGTGC AGGAAAAATT AGCAGCACTT GAAGCCAGTA TTGAACAGCG TTTGAAATGG 9720

GCAGGTGGAG CAAATCCTGC ATTGGCACCA GTCTTGCAAG ATTTTGAAGC AACAATTGCT 9780

GAAAGAAGGA ATCTTGTCCT TAAAGAAAGC CAAAGAGCAA GTCAGGTAAC TTTCCTTTGC 9840

AGCAATATTA TTCATTTTGA AAGTTTACGA ACTAGAACTG CAGAAGCCTT AAATCTTGAT 9900

GCTTCGTTAT TTGAACTTAT CAAACGCTGT CAGCAAATGT GTTCATTTGC ATCACAGTTT 9960

AACAGTTCAG TTTCTGAATT AGAACTTCGT TTACTACAAA GAGTGGGTAC TAATCTTGAA 10020

CATGCTATTG GCAGCTCTGA ATGGCTTTTG TCAGCACACA AGCAACTGAG TCAAGACATG 10080

TCTACTCAAA GAGTCGTTCA GACAGAGAAA GAACAACAGA TAGAAACTGT CTGTGAAACA 10140

ATTCAGAACT TAGTTGATAA CATTAAGACA GTTCTCACTG GTCACAACAG GCAACTTGGA 10200

GATGTCAAGC ATCTACTAAA AGCAATGGCC AAGGATGAAG AAGCTGCATT AGCAGATGGT 10260

GATGATGTTC CTTATGAGAA CAGTGTCAGG CAGTTCTTAG GGGAATACAA GTCATGGCAA 10320

GACAACATTC AGACAGTGTT GTTTACATTA GTTCAGGCTA TGGGTCAAGT GCGTAGTCAG 10380

GAGCATGTTG AAATGCTGCA AGAAATAACT CCCACCTTGA AAGAGCTGAA AACACAAAGT 10440

CAGAGCATCT ACAATAATCT AGTGAGTTTC GCATCACCTC TAGTCACAGA TGCAACAAAT 10500

GAATGTTCAA GTCCAACATC ATCTGCTACC TATCAGCCAA CCTTTGCTGC AGCAGTAAGA 10560

AGCAACACTG GCCAGAAGAC TCAGCCTGAA GTTATGTCAC AGAATGCAAG AAAGGCAATT 10620

CAGAAAAATC TTGCTACATC AGCAGATACT CCACCAAGCA CAGTCCCAGG AACAGGCAAG 10680

AGTGTTGCTT GTAGTCCTAA AAAAGCAGTC AGAGATCCTA AAACTGGAAA AGCTGTGCAG 10740

GAAAGAAACT CATATGCAGT GAGTGTGTGG AAGAGGGTCA AAGCCAAGTT AGAGGGCCGA 10800

GATGTTGATC CTAACAGGAG AATGTCTGTT GCTGAACAGG TTGACTATGT GATTAAGGAA 10860

GCAACTAATC TAGATAACTT GGCTCAGCTG TATGAAGGTT GGACAGCCTG GGTATGA 10917

Domain Profile

S: 3     gfderveilaskqkpkklllrGsdgkeypyLvk.gkeDlrqdervlqlfslvNtlLakdk  61

         ++  +++il++k+kpkkll++Gsdgk ypyL+k g+eDl+ der++q++s+vNt++a+ +

Q: 2099  SVGGTITILPTKTKPKKLLFLGSDGKNYPYLFKvGLEDLHLDERIMQFLSIVNTMFATIN  2158

         566789**************************559*************************

S: 62    etsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpi..syrykd  119

         +++++++++r+y+V+pl+trsgli+wv+++++L+ l+k++++++a+l++q++  sy++++

Q: 2159  RQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAqdSYQTPQ  2218

         ***************************************************999******

S: 120   lstvqar.........kpklkhlkls.........levfkevlenlv...pkdllkklll  158

         ++ +++r         +p+lk++ ls         l+v+k+vle+l+   p++ll+k+l+

Q: 2219  NPGIVPRpselyyskiGPALKAVGLSldvsrrdwpLNVMKAVLEELMeatPPNLLAKELW  2278

         ****************999999999999****************999999**********

S: 159   ekfpspeewfelrkaytrslAvislvgyiLgLgdrhlenllidqetgevvhidfgvafek  218

         +++++p+ew++++++y+rs+Av+s+vgyi+gLgdrhl+n+lid++tgevvhid++v+fek

Q: 2279  SSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEK  2338

         ************************************************************

S: 219   aktqlkvpekvPFRLTrnivnalgvtgveGvfrasceavlrvlreskeklltiLevflyd  278

         +k+ l+vpekvPFR+T+ni++algvtgveGvfr sce+vl+++r+ +e+llt+Le+f+yd

Q: 2339  GKS-LRVPEKVPFRMTHNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYD  2397

         ***.********************************************************

S: 279   plvdwkk...............k  286

         plvdw+                +

Q: 2398  PLVDWTAggeagfagavyggggQ  2420

         ******97777766666554432

Domain Sequence
(FASTA)

SVGGTITILP TKTKPKKLLF LGSDGKNYPY LFKVGLEDLH LDERIMQFLS IVNTMFATIN 60

RQETPRFHAR HYSVTPLGTR SGLIQWVDGA TPLFGLYKRW QQREAALQAQ KAQDSYQTPQ 120

NPGIVPRPSE LYYSKIGPAL KAVGLSLDVS RRDWPLNVMK AVLEELMEAT PPNLLAKELW 180

SSCTTPDEWW RVTQSYARST AVMSMVGYII GLGDRHLDNV LIDMTTGEVV HIDYNVCFEK 240

GKSLRVPEKV PFRMTHNIET ALGVTGVEGV FRLSCEQVLH IMRRGRETLL TLLEAFVYDP 300

LVDWTAGGEA GFAGAVYGGG GQ 322

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016301	; F:kinase activity
GO:0016773	; F:phosphotransferase activity, alcohol group as acceptor

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR014009	; PIK_FAT.

Pfam

PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013