EKS-SUS-00172

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00172

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	511.2	9.2E-154	4	284	281

Status

Unreviewed

Ensembl Protein

ENSSSCP00000001113

UniProt Accession

F1RV90;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000001042	ENSSSCP00000001113	ENSSSCT00000001136

Organism

Sus scrofa

Functional Description

Protein Length

624

Protein Sequence
(FASTA)

MNRYTTMRQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 60

NVIKLKEVIR ENDHLYFIFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 120

FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP 180

IDVWAVGSIM AELYTLRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYQL ASSMNFRFPQ 240

CAPINLKTLI PNASNEAIQL MTEMLSWDPK KRPTASQALK HPYFQVGQVL GPSSHHLESK 300

QPLNKQVQPL ESKPSVGDLE PKLLPDINDQ TAGQPQPRNS HQPLQSIQPP QDTSGQQAPK 360

QQSQQKQPQT LFPRIVKNMP IKPNGTLGHK GARRRWGPTV FKAGDSGEES EDYDFGASHS 420

KKPSMGVFKE TRRKDSPFRL PEPVPTGSNH SSGENKSLPA AGSLKSDSEL STASAAKQYY 480

LKQSRYLPGV NPKNVSLVTR GKDINPYSWN NQLFPKSLGP IGAELAFKRN NAVGTLGSYA 540

TYNQSGYIPS FLKKEVGSAG QRIPLVPLGA TASEYSWNTK MGRGQFSGPT YNPTAKNLNM 600

VNRAQPVPSV HGRTDWVAKY GGHR 624

Nucleotide Sequence
(FASTA)

ATGAACCGAT ACACAACCAT GAGACAGTTG GGAGACGGTA CCTATGGGAG CGTGCTGATG 60

GGCAAGAGTA ACGAATCGGG CGAGCTGGTG GCCATCAAAA GAATGAAGAG AAAGTTCTAT 120

TCTTGGGATG AATGTATGAA CTTGAGAGAA GTTAAGTCTC TGAAGAAACT TAATCATGCC 180

AATGTGATTA AACTGAAAGA AGTTATCCGA GAAAATGACC ATCTTTATTT TATATTTGAA 240

TATATGAAAG AAAACCTCTA TCAATTAATG AAAGACAGAA ACAAGTTGTT CCCTGAGTCT 300

GTCATCAGAA ATATTATGTA TCAAATATTG CAAGGGCTGG CATTTATCCA TAAACATGGT 360

TTTTTTCACA GGGATATGAA ACCAGAAAAC TTGCTCTGCA TGGGCCCAGA ACTTGTGAAA 420

ATTGCTGATT TTGGACTTGC GCGAGAATTA AGGTCACAGC CACCATATAC CGATTATGTA 480

TCCACCAGAT GGTATCGTGC TCCTGAAGTT TTATTAAGAT CTTCAGTTTA CAGCTCTCCC 540

ATCGATGTGT GGGCTGTTGG GAGTATAATG GCTGAACTGT ATACGCTAAG ACCTCTTTTC 600

CCCGGGACCA GCGAGGTCGA TGAAATCTTT AAGATTTGCC AAGTTTTAGG GACGCCCAAA 660

AAAAGCGACT GGCCAGAAGG GTACCAGCTG GCATCCTCTA TGAATTTCCG CTTTCCCCAG 720

TGTGCGCCCA TAAACTTAAA AACTCTTATT CCCAATGCCA GTAACGAAGC TATTCAGCTT 780

ATGACTGAAA TGTTGAGTTG GGATCCAAAG AAACGACCAA CAGCCAGCCA GGCACTGAAA 840

CACCCATATT TTCAAGTTGG TCAAGTCTTA GGCCCCTCCT CGCATCATCT GGAATCGAAA 900

CAGCCTTTAA ATAAGCAGGT GCAACCACTA GAATCAAAGC CATCTGTAGG TGACCTCGAA 960

CCTAAGCTTC TGCCAGACAT AAATGATCAG ACGGCCGGAC AGCCCCAGCC GAGAAACAGC 1020

CACCAGCCAC TGCAGTCCAT CCAGCCGCCG CAGGACACGA GTGGCCAGCA AGCCCCAAAG 1080

CAGCAGAGTC AACAGAAACA GCCCCAAACG CTATTTCCAC GTATCGTCAA AAACATGCCA 1140

ATCAAGCCCA ACGGCACTCT GGGCCACAAA GGTGCCAGGA GGCGCTGGGG TCCGACTGTG 1200

TTCAAGGCTG GAGACAGCGG GGAAGAGTCT GAGGACTATG ATTTCGGAGC CTCCCATTCC 1260

AAGAAGCCAA GCATGGGTGT TTTCAAAGAG ACCAGGAGAA AAGACTCTCC ATTTCGGCTC 1320

CCAGAGCCGG TACCCACAGG CTCCAACCAC TCATCGGGGG AGAACAAGAG CTTACCTGCT 1380

GCCGGTTCCC TAAAATCTGA CTCTGAATTG TCGACTGCTT CAGCAGCTAA ACAGTACTAT 1440

TTGAAACAAT CCAGATACCT TCCAGGTGTA AATCCCAAGA ACGTATCCTT GGTAACCAGA 1500

GGGAAGGACA TAAACCCCTA TTCCTGGAAT AACCAGTTAT TTCCAAAGTC ACTGGGACCC 1560

ATTGGGGCAG AACTTGCTTT CAAAAGGAAT AATGCAGTAG GAACTCTTGG AAGTTATGCT 1620

ACTTACAATC AGTCGGGATA TATTCCTTCC TTTCTCAAAA AAGAAGTGGG GTCGGCTGGC 1680

CAGAGGATAC CCTTGGTCCC TCTTGGTGCA ACAGCTTCAG AGTATTCCTG GAACACAAAA 1740

ATGGGTCGGG GGCAGTTTTC AGGACCTACT TATAATCCTA CAGCCAAGAA TCTAAACATG 1800

GTGAACCGCG CACAGCCAGT CCCCTCCGTG CACGGGAGGA CAGACTGGGT GGCCAAGTAC 1860

GGAGGCCACC GGTAG 1875

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++++lGdGt+g+vl++ks+++gelvaik+mkrkf+s++e++nlrevkslkkln h+n+

Q: 4     YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         iklkevi  rend+ly+++e+m+enlyql+kdr+kl++es++++i+yqil+glafihkhg

Q: 63    IKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs+vyssp

Q: 121   FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavG+++ae+++lrplfPG+se+d+ifki++vlGtPkk++w+e+y+las++n++fpq

Q: 181   IDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         + +++lktl++nas+ea++l++++l++dP++r+ta+qalk+pyf

Q: 241   CAPINLKTLIPNASNEAIQLMTEMLSWDPKKRPTASQALKHPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTMRQLGDG TYGSVLMGKS NESGELVAIK RMKRKFYSWD ECMNLREVKS LKKLNHANVI 60

KLKEVIREND HLYFIFEYMK ENLYQLMKDR NKLFPESVIR NIMYQILQGL AFIHKHGFFH 120

RDMKPENLLC MGPELVKIAD FGLARELRSQ PPYTDYVSTR WYRAPEVLLR SSVYSSPIDV 180

WAVGSIMAEL YTLRPLFPGT SEVDEIFKIC QVLGTPKKSD WPEGYQLASS MNFRFPQCAP 240

INLKTLIPNA SNEAIQLMTE MLSWDPKKRP TASQALKHPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0030496	; C:midbody
GO:0072686	; C:mitotic spindle
GO:0005634	; C:nucleus
GO:0001917	; C:photoreceptor inner segment
GO:0001750	; C:photoreceptor outer segment
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0003713	; F:transcription coactivator activity
GO:0045494	; P:photoreceptor cell maintenance
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013