EKS-SUS-00174

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00174

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	430.7	3.1E-129	4	288	285

Status

Unreviewed

Ensembl Protein

ENSSSCP00000002739

UniProt Accession

F1SA05;

Protein Name

Protein Synonyms/Alias

Gene Name

MOK

Gene Synonyms/Alias

MOK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000002531	ENSSSCP00000002739	ENSSSCT00000002810

Organism

Sus scrofa

Functional Description

Protein Length

424

Protein Sequence
(FASTA)

MKNYKAISKI GEGTFSEVMK MQNLRDGNYY ACKQMKQHFE SIEQVNSLRE IQALRRLNPH 60

PNILTLHEVL FDRKSGSLAL ICELMDMNIY ELIRDCTGRR QPLSEKKISR YMYQLCKSLD 120

HMHRNGIFHR DVKPENILIK QDVLKLGDFG SCRSVCSKQP HTEYVSTRWY RAPECLLTDG 180

FYSYKMDLWS AGCVLYEIAS LQPLFPGANE LDQISKIHDI MGTPAAKTLS KFQQSRAVSF 240

DFPFTKGSGI PVPTASLSPQ CLSLLRAMVA YDPDDRVTAH QALQHPYFRE QRAAEKQASH 300

GRRVTACFPE RPVAPELLKQ TWQMSTAGRK QKQPLRPEEG RPRRQGPACL VELPRLQLSG 360

GTTLSSYASP ALQSMFAPGA DGKVPVLRPP KFMGASQKTA AQKAVKPNLK QCRLPTIGRR 420

DGGY 424

Nucleotide Sequence
(FASTA)

ATGAAGAACT ATAAAGCAAT CAGCAAAATA GGAGAGGGAA CGTTTTCTGA AGTTATGAAG 60

ATGCAGAACC TGAGAGATGG AAACTACTAT GCATGTAAAC AAATGAAACA GCACTTTGAA 120

AGTATCGAGC AAGTGAACAG TCTGCGAGAG ATACAAGCCC TGAGGCGCCT GAATCCACAC 180

CCAAACATCC TCACGCTGCA CGAAGTGCTT TTTGACAGAA AATCTGGTTC TCTTGCGCTA 240

ATATGTGAAC TTATGGACAT GAATATTTAT GAGCTAATTC GAGATTGCAC AGGGCGAAGA 300

CAGCCGTTAT CAGAAAAGAA AATTTCGCGC TATATGTACC AGTTGTGTAA ATCCCTTGAT 360

CACATGCACA GAAATGGAAT ATTTCACAGA GATGTAAAAC CAGAAAATAT ATTAATAAAG 420

CAGGATGTCC TGAAGTTAGG GGACTTCGGG TCCTGCCGGA GCGTCTGTTC TAAGCAGCCG 480

CACACAGAGT ACGTCTCCAC CCGCTGGTAC CGGGCCCCGG AGTGTCTGCT CACCGACGGC 540

TTCTACTCCT ACAAGATGGA CCTGTGGAGC GCGGGCTGCG TGCTCTACGA GATCGCCAGC 600

CTGCAGCCGC TCTTCCCTGG AGCCAACGAG CTGGACCAGA TCTCAAAAAT CCACGACATC 660

ATGGGCACGC CTGCTGCAAA GACCCTCAGC AAGTTCCAAC AGTCGAGAGC TGTGAGTTTC 720

GACTTTCCTT TTACAAAGGG GTCAGGAATC CCTGTGCCAA CGGCCAGTCT GTCCCCGCAG 780

TGCCTCTCGC TCCTGCGCGC AATGGTGGCC TATGACCCCG ATGACAGGGT CACTGCCCAC 840

CAGGCCCTGC AGCATCCCTA CTTCCGAGAG CAGAGGGCAG CTGAGAAGCA GGCCAGCCAC 900

GGGAGGAGAG TCACGGCCTG CTTTCCAGAG CGCCCCGTGG CCCCCGAGCT CCTCAAGCAA 960

ACCTGGCAGA TGTCCACGGC GGGCAGGAAG CAGAAACAGC CCCTGCGGCC AGAGGAGGGC 1020

CGCCCCCGGA GACAGGGGCC CGCCTGCCTG GTGGAGCTGC CCAGACTCCA GCTTTCGGGG 1080

GGGACCACGC TGTCGTCTTA CGCCAGCCCC GCGCTGCAGT CCATGTTTGC CCCGGGAGCC 1140

GACGGGAAGG TCCCGGTGCT GAGACCCCCG AAGTTCATGG GCGCGAGCCA GAAGACAGCC 1200

GCGCAGAAGG CCGTCAAGCC GAACCTGAAG CAGTGCCGGC TGCCCACGAT AGGACGGAGA 1260

GACGGCGGCT ACTGA 1275

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         yk+i+k+G+Gtf+ev+++++l++g+++a+k+mk++fes+e+v++lre+++l++ln+h+ni

Q: 4     YKAISKIGEGTFSEVMKMQNLRDGNYYACKQMKQHFESIEQVNSLREIQALRRLNPHPNI  63

         99**********************************************************

S: 61    iklkeviidrendslylvlelmeenlyqlikd...rrkllsesklksilyqilkglafih  117

         ++l+ev++dr+++sl+l++elm++n+y+li+d   rr+ lse+k+ +++yq++k+l+++h

Q: 64    LTLHEVLFDRKSGSLALICELMDMNIYELIRDctgRRQPLSEKKISRYMYQLCKSLDHMH  123

         *******************************9999*************************

S: 118   khgffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvy  177

         ++g+fhrd+kPenilik ++++kl+dfG++r+v sk+P+t+yvstrwyraPe+ll++g+y

Q: 124   RNGIFHRDVKPENILIK-QDVLKLGDFGSCRSVCSKQPHTEYVSTRWYRAPECLLTDGFY  182

         *****************.******************************************

S: 178   sspldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlk  237

         s+++dlw++Gcvl+e+a+l+plfPGa+e+dqi+ki++++GtP+ k++++ +++++a++++

Q: 183   SYKMDLWSAGCVLYEIASLQPLFPGANELDQISKIHDIMGTPAAKTLSK-FQQSRAVSFD  241

         ************************************************9.**********

S: 238   fpqvegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         fp+++gs+++  ++++s ++l+ll++++aydPd+r+ta+qal++pyf

Q: 242   FPFTKGSGIPVPTASLSPQCLSLLRAMVAYDPDDRVTAHQALQHPYF  288

         **********************************************9

Domain Sequence
(FASTA)

YKAISKIGEG TFSEVMKMQN LRDGNYYACK QMKQHFESIE QVNSLREIQA LRRLNPHPNI 60

LTLHEVLFDR KSGSLALICE LMDMNIYELI RDCTGRRQPL SEKKISRYMY QLCKSLDHMH 120

RNGIFHRDVK PENILIKQDV LKLGDFGSCR SVCSKQPHTE YVSTRWYRAP ECLLTDGFYS 180

YKMDLWSAGC VLYEIASLQP LFPGANELDQ ISKIHDIMGT PAAKTLSKFQ QSRAVSFDFP 240

FTKGSGIPVP TASLSPQCLS LLRAMVAYDP DDRVTAHQAL QHPYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013