EKS-SUS-00173

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00173

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	470.2	2.8E-141	17	267	251

Status

Unreviewed

Ensembl Protein

ENSSSCP00000002837

UniProt Accession

F1S7C7;

Protein Name

Protein Synonyms/Alias

Gene Name

ICK

Gene Synonyms/Alias

ICK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000002628	ENSSSCP00000002837	ENSSSCT00000002916

Organism

Sus scrofa

Functional Description

Protein Length

612

Protein Sequence
(FASTA)

SLLLGISVLF VSVFSFRMKR KFYSWEECMN LREVKSLKKL NHANVVKLKE VIRENDHLYF 60

IFEYMKENLY QLIKERNKLF PESAIRNIMY QILQGLAFIH KHGFFHRDLK PENLLCMGPE 120

LVKIADFGLA REIRSRPPYT DYVSTRWYRA PEVLLRSTNY SSPIDIWAVG CIMAEVYTLR 180

PLFPGASEID TIFKICQVLG TPKKTDWPEG YQLSSAMNFR WPQCVPNNLK TLIPNASSEA 240

VQLLRDMLQW DPKKRPTASQ ALRYPYFQIG HPLGSTTQSL QSSGKPQKDV LEKAGPPPHL 300

KPVPPAQPPT KPHTRISSRP HQASHPPQHL VYPYKAEASR TDHLPEDKPS PLLLPSLHTK 360

HPQAKMLTGL EHKNGEIKPK SRRRWGLVSR STKDSDDWAE LDDSDFSPSF TGIDLKNKKR 420

QSDETLCRFE SVLDLKPSEP VSTGSSAPTQ GSYPRRDTPT LRSAAKQHYL KHSRYLPGIN 480

IRNGILPNPG KDFIPSNPWS SSGLSGKSSG TVSVISKINS VGSCSTSSSG LAGNYIPSFL 540

KKEIGSAMQR VHLAPVPDPP PGYSSLKAVR PHPGRPFFHT QPRSTPGLLP RPPAAQPVHG 600

RTDWVSKYAS RR 612

Nucleotide Sequence
(FASTA)

AGCCTGTTAT TGGGAATAAG TGTGCTATTT GTTTCTGTCT TCTCTTTTAG AATGAAAAGA 60

AAGTTTTATT CCTGGGAGGA ATGCATGAAC CTTCGGGAGG TTAAGTCTTT AAAGAAGCTC 120

AACCATGCCA ATGTTGTAAA GTTAAAAGAA GTTATCAGGG AAAATGATCA TCTTTATTTT 180

ATCTTTGAGT ACATGAAGGA AAATCTTTAC CAGCTTATTA AAGAAAGGAA TAAATTGTTT 240

CCCGAGTCTG CTATCAGAAA TATCATGTAT CAGATATTGC AAGGACTTGC ATTTATTCAC 300

AAACACGGCT TCTTCCATCG GGACTTAAAG CCAGAGAACC TCCTCTGTAT GGGACCCGAG 360

CTCGTGAAAA TTGCTGACTT TGGATTGGCT CGAGAAATTC GATCAAGACC ACCGTACACT 420

GACTATGTAT CTACCAGATG GTACCGGGCC CCAGAGGTGC TCCTGCGCTC CACCAACTAC 480

AGCTCCCCCA TCGACATCTG GGCCGTGGGC TGCATCATGG CAGAAGTGTA CACCCTCCGG 540

CCACTCTTCC CCGGGGCCAG TGAGATCGAC ACGATCTTCA AAATCTGCCA AGTGCTGGGG 600

ACTCCGAAAA AGACTGACTG GCCTGAAGGC TACCAACTTT CGAGTGCGAT GAACTTCCGC 660

TGGCCCCAGT GTGTACCCAA TAACCTGAAG ACCCTGATTC CAAATGCCAG CAGCGAGGCA 720

GTTCAGCTCC TGAGAGACAT GCTTCAGTGG GACCCCAAGA AACGGCCAAC AGCTAGTCAG 780

GCACTTCGAT ATCCTTACTT CCAGATTGGG CACCCCCTGG GCAGCACCAC ACAGAGCCTT 840

CAGAGTTCAG GAAAACCACA GAAGGACGTT CTGGAAAAGG CAGGCCCACC GCCTCACTTA 900

AAGCCGGTCC CTCCTGCCCA GCCCCCAACC AAGCCACACA CGCGCATCTC TTCGAGACCA 960

CATCAAGCCA GCCACCCCCC TCAGCATCTC GTGTACCCCT ACAAAGCCGA GGCTTCCAGG 1020

ACAGACCACC TTCCAGAAGA CAAGCCCAGC CCTTTGCTCT TGCCGTCTCT CCACACCAAG 1080

CATCCTCAGG CAAAAATGCT CACTGGCCTG GAGCACAAAA ATGGTGAGAT CAAGCCAAAG 1140

AGTAGAAGAA GGTGGGGTCT CGTTTCCCGG TCAACAAAGG ATTCTGATGA CTGGGCTGAA 1200

CTGGATGACT CGGATTTTAG CCCATCGTTC ACCGGGATTG ACCTGAAGAA CAAAAAAAGA 1260

CAGAGCGATG AGACCCTGTG CAGATTTGAG AGCGTTCTGG ACCTGAAGCC CTCAGAGCCA 1320

GTGAGCACCG GAAGTAGCGC CCCCACCCAG GGGTCCTACC CCAGGCGTGA CACGCCCACC 1380

CTGAGGTCAG CGGCCAAGCA GCACTACCTG AAGCACTCCC GGTACCTGCC TGGAATAAAT 1440

ATAAGAAACG GCATACTCCC GAATCCAGGC AAGGATTTCA TTCCATCCAA TCCATGGTCC 1500

AGTTCTGGTT TGTCTGGAAA ATCTTCAGGG ACGGTATCTG TGATCAGCAA GATAAATTCA 1560

GTTGGTTCCT GCTCTACAAG TTCTAGTGGA CTGGCTGGAA ACTATATCCC TTCCTTTCTG 1620

AAAAAAGAAA TCGGTTCTGC TATGCAGAGG GTCCACTTGG CACCTGTTCC CGACCCTCCC 1680

CCTGGTTATT CTTCCCTGAA GGCTGTGCGA CCTCATCCCG GGCGACCTTT TTTCCACACC 1740

CAGCCTAGAA GCACTCCCGG GCTGCTGCCT CGGCCTCCGG CCGCCCAGCC TGTGCATGGC 1800

CGCACGGACT GGGTTTCCAA GTATGCGTCT CGGCGATGA 1839

Domain Profile

S: 31    kmkrkfesleevtnlrevkslkklnahdniiklkeviidrendslylvlelmeenlyqli  90

         +mkrkf+s+ee++nlrevkslkkln h+n++klkevi  rend+ly+++e+m+enlyqli

Q: 17    RMKRKFYSWEECMNLREVKSLKKLN-HANVVKLKEVI--RENDHLYFIFEYMKENLYQLI  73

         8************************.***********..*********************

S: 91    kdrrkllsesklksilyqilkglafihkhgffhrdlkPenilikgselvkladfGlarev  150

         k+r+kl++es++++i+yqil+glafihkhgffhrdlkPen+l++g+elvk+adfGlare+

Q: 74    KERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREI  133

         ************************************************************

S: 151   rsknPytdyvstrwyraPevllrsgvysspldlwavGcvlaevavlrplfPGaseidqif  210

         rs++PytdyvstrwyraPevllrs++yssp+d+wavGc++aev++lrplfPGaseid+if

Q: 134   RSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIF  193

         ************************************************************

S: 211   kilevlGtPkkkewdeayklasalnlkfpqvegsslktlvsnaskealellkdllaydPd  270

         ki++vlGtPkk++w+e+y+l+sa+n+++pq+++++lktl++nas+ea++ll+d+l++dP+

Q: 194   KICQVLGTPKKTDWPEGYQLSSAMNFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPK  253

         ************************************************************

S: 271   erataqqalkypyf  284

         +r+ta+qal+ypyf

Q: 254   KRPTASQALRYPYF  267

         *************9

Domain Sequence
(FASTA)

RMKRKFYSWE ECMNLREVKS LKKLNHANVV KLKEVIREND HLYFIFEYMK ENLYQLIKER 60

NKLFPESAIR NIMYQILQGL AFIHKHGFFH RDLKPENLLC MGPELVKIAD FGLAREIRSR 120

PPYTDYVSTR WYRAPEVLLR STNYSSPIDI WAVGCIMAEV YTLRPLFPGA SEIDTIFKIC 180

QVLGTPKKTD WPEGYQLSSA MNFRWPQCVP NNLKTLIPNA SSEAVQLLRD MLQWDPKKRP 240

TASQALRYPY F 251

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0043231	; C:intracellular membrane-bounded organelle
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013