EKS-SUS-00055

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00055

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	377.9	3.5E-113	427	712	286

Status

Unreviewed

Ensembl Protein

ENSSSCP00000003635

UniProt Accession

F1RJC5;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK11B

Gene Synonyms/Alias

CDK11B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000003352	ENSSSCP00000003635	ENSSSCT00000003721

Organism

Sus scrofa

Functional Description

Protein Length

784

Protein Sequence
(FASTA)

MGDEKDSWKV KTLDEILQEK KRRKEQEEKA EIKRLKNVRQ IDNILKIDMR KESEVPCHML 60

ASNFSGSGPY RREDSMEDRG EEDDSLAIKP PQQMSRKEKA HHRKDEKRKE KRRHRSHSAE 120

GGIARKHARV KEKEREHERR KRHREEQDKA RREWERQKRR EMAREHSRRE RDRLEQLERK 180

RERERKMREQ QKEQREQKER ERRAEERRKE REARREVSTH HRTVREDYGD KVKASHWSRS 240

PLRPPRERFE LGDGRKPVKE EKVEERDLLS DLQDVSDSER KTSSAESSSA ESGSGSEEEE 300

QSTSGSEEDA AERRPPVSGA SKTRWVCDEA SGPGRLSREE VSEEDVSEEE EREDDNHVLV 360

VPESRFDRDS GESEEGEEEA GEGTPQSSAL TEGDFVPDSP ALSPIELKQE LPKYLPALQG 420

CRSVEEFQCL NRIEEGTYGV VYRAKDKKTD EIVALKRLKM EKEKEGFPIT SLREINTILK 480

AQHPNIVTVR EIVVGSNMDK IYIVMNYVEH DLKSLMETMK QPFLPGEVKT LMIQLLRGVK 540

HLHDNWILHR DLKTSNLLLS HAGILKVGDF GLAREYGSPL KAYTPVVVTL WYRAPELLLG 600

AKEYSTAVDM WSVGCIFGEL LTQKPLFPGK SDIDQINKVF KDLGTPSEKI WPGYNDLPAV 660

KKMTFTEYPY NNLRKRFGAL LSDQGFDLMN KFLTYFPGRR VSAEDGLKHE YFRETPLPID 720

PSMFPTWPAK SEQQRVKRGT SPRPPEGGLG YSQLGDDDLK ETGFHLTTTN QGASAAGPGF 780

SLKF 784

Nucleotide Sequence
(FASTA)

ATGGGTGATG AAAAGGACTC TTGGAAAGTG AAAACTTTAG ATGAAATTCT TCAGGAAAAG 60

AAACGACGGA AAGAACAAGA GGAAAAAGCA GAGATAAAAC GCTTAAAAAA TGTAAGACAG 120

ATTGATAACA TACTAAAAAT TGACATGAGA AAAGAGTCTG AAGTCCCCTG TCACATGCTG 180

GCTTCAAATT TTTCAGGTTC TGGGCCATAC AGAAGAGAGG ACTCCATGGA AGACAGAGGA 240

GAGGAAGACG ATTCCTTGGC CATCAAACCG CCCCAGCAAA TGTCTCGGAA AGAAAAGGCT 300

CATCACAGGA AAGATGAAAA GAGAAAAGAG AAGCGTAGGC ATCGCAGTCA TTCAGCCGAA 360

GGGGGTATAG CACGGAAGCA CGCCCGAGTG AAGGAGAAGG AGCGGGAGCA CGAGCGGCGG 420

AAGCGCCACC GGGAGGAGCA GGACAAAGCC CGCCGGGAGT GGGAGAGACA GAAGCGCAGG 480

GAGATGGCCC GGGAGCACTC CCGGCGGGAG AGGGACCGCC TGGAGCAGCT GGAAAGGAAG 540

CGGGAGCGCG AACGCAAGAT GCGCGAGCAG CAGAAGGAGC AGCGGGAGCA GAAGGAGCGC 600

GAGCGGCGGG CCGAGGAGCG GCGCAAGGAG CGGGAGGCGC GGCGGGAAGT ATCTACACAT 660

CACCGGACCG TGAGGGAGGA CTACGGCGAC AAGGTCAAAG CCAGCCACTG GAGTCGGAGC 720

CCGCTTCGGC CACCTCGAGA GCGGTTCGAG CTGGGAGATG GCCGGAAGCC AGTAAAAGAG 780

GAGAAGGTGG AGGAGAGAGA CCTGCTCTCT GACCTGCAGG ACGTCAGCGA CAGTGAGCGG 840

AAGACCAGCT CGGCCGAGTC CTCCTCGGCG GAGTCTGGGT CCGGCTCAGA GGAGGAGGAG 900

CAAAGCACGT CCGGCTCAGA GGAGGACGCA GCCGAGCGGA GACCCCCCGT CTCTGGGGCT 960

TCGAAGACCC GCTGGGTCTG TGATGAGGCT TCCGGCCCGG GGCGCCTGAG CCGAGAAGAA 1020

GTGAGCGAGG AGGACGTGAG CGAAGAGGAG GAGCGAGAGG ACGACAACCA CGTCCTGGTC 1080

GTTCCAGAGT CACGGTTTGA CCGGGATTCC GGAGAGAGTG AAGAGGGGGA GGAGGAGGCA 1140

GGCGAGGGCA CCCCCCAGAG CAGCGCTCTC ACCGAAGGAG ACTTCGTGCC CGACTCCCCG 1200

GCCCTGTCGC CCATCGAGCT CAAGCAGGAG CTGCCCAAGT ACCTGCCCGC CCTGCAGGGC 1260

TGCCGGAGCG TGGAGGAGTT CCAGTGCCTG AACAGGATCG AGGAGGGTAC CTACGGGGTG 1320

GTGTACAGAG CGAAGGACAA GAAGACAGAT GAGATCGTGG CTCTGAAGCG GCTGAAGATG 1380

GAGAAGGAGA AGGAGGGCTT CCCCATCACA TCGCTGAGGG AGATCAACAC CATCCTCAAG 1440

GCGCAGCACC CCAACATCGT CACCGTCAGG GAGATCGTGG TGGGCAGCAA CATGGACAAG 1500

ATCTACATCG TGATGAACTA CGTGGAGCAC GACCTCAAGA GCCTCATGGA GACCATGAAG 1560

CAGCCCTTCT TGCCAGGGGA GGTGAAGACC TTGATGATCC AGCTGCTGCG CGGCGTGAAG 1620

CACCTGCACG ACAACTGGAT CCTGCACCGC GACCTCAAGA CGTCCAACCT GCTGCTGAGC 1680

CACGCGGGCA TCCTCAAGGT GGGGGACTTC GGGCTGGCAC GGGAGTACGG GTCCCCCCTG 1740

AAGGCCTACA CCCCGGTCGT GGTGACCCTG TGGTACCGTG CCCCGGAACT GCTGCTCGGG 1800

GCCAAGGAGT ACTCCACGGC CGTGGACATG TGGTCGGTGG GCTGCATCTT CGGGGAGCTG 1860

CTCACCCAGA AGCCTCTGTT CCCGGGCAAG TCGGACATCG ACCAGATCAA CAAAGTGTTC 1920

AAGGACCTGG GCACCCCCAG CGAGAAGATC TGGCCGGGGT ACAATGATCT CCCCGCGGTC 1980

AAGAAGATGA CCTTCACCGA GTACCCATAC AACAACCTCC GCAAGCGCTT CGGCGCTCTG 2040

CTCTCGGACC AGGGCTTCGA CCTCATGAAC AAGTTCCTGA CCTACTTCCC CGGGCGGAGG 2100

GTCAGTGCCG AGGACGGCCT GAAGCACGAG TATTTCCGCG AGACACCCCT CCCCATCGAC 2160

CCCTCCATGT TCCCCACGTG GCCCGCCAAG AGCGAGCAGC AGAGAGTGAA GCGAGGCACC 2220

AGCCCGCGAC CCCCCGAGGG AGGCCTGGGC TACAGCCAGC TGGGCGACGA CGACCTGAAG 2280

GAGACGGGTT TCCACCTCAC CACCACCAAC CAGGGTGCCT CGGCCGCAGG CCCGGGCTTC 2340

AGCCTCAAGT TCTGA 2355

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         +++l++i+eGtyg+vy+akdk+t+e+vAlK++++ekekeg+pit+lrEi+++ + +h+ni

Q: 427   FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI  486

         7899********************************************************

S: 61    vkLlevva.kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         v++ e+v+ ++ +k+y+v++++e+dLk+l++++k+  + + evk+l++qll+g+++lH+n

Q: 487   VTVREIVVgSNMDKIYIVMNYVEHDLKSLMETMKQ-PFLPGEVKTLMIQLLRGVKHLHDN  545

         *******95666***********************.9999********************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYs  179

         +ilHRDlK++NlL+s+ g+lk++DfGlar+++splk+yt++vvTlwYraPelLlgakeYs

Q: 546   WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS  605

         ************************************************************

S: 180   tavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksf  238

         tavD+Wsvgci+ ellt+kplf+gks+idq++++fk lgtpsek+wp++++lp +k ++f

Q: 606   TAVDMWSVGCIFGELLTQKPLFPGKSDIDQINKVFKDLGTPSEKIWPGYNDLPAVKkMTF  665

         ********************************************************99**

S: 239   pkkkkkklkekvkklkek.aldllekllaldpkkRisakealqhkyf  284

         +++++++l++++ +l ++ ++dl++k+l++ p +R+sa++ l+h+yf

Q: 666   TEYPYNNLRKRFGALLSDqGFDLMNKFLTYFPGRRVSAEDGLKHEYF  712

         ************8877554***************************9

Domain Sequence
(FASTA)

FQCLNRIEEG TYGVVYRAKD KKTDEIVALK RLKMEKEKEG FPITSLREIN TILKAQHPNI 60

VTVREIVVGS NMDKIYIVMN YVEHDLKSLM ETMKQPFLPG EVKTLMIQLL RGVKHLHDNW 120

ILHRDLKTSN LLLSHAGILK VGDFGLAREY GSPLKAYTPV VVTLWYRAPE LLLGAKEYST 180

AVDMWSVGCI FGELLTQKPL FPGKSDIDQI NKVFKDLGTP SEKIWPGYND LPAVKKMTFT 240

EYPYNNLRKR FGALLSDQGF DLMNKFLTYF PGRRVSAEDG LKHEYF 286

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006915	; P:apoptotic process
GO:0001824	; P:blastocyst development
GO:0007088	; P:regulation of mitosis

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013