EKS-SUS-00082

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00082

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	436.6	8.0E-131	2153	2479	327

Status

Unreviewed

Ensembl Protein

ENSSSCP00000003699

UniProt Accession

F1RHR8;

Protein Name

Protein Synonyms/Alias

Gene Name

MTOR

Gene Synonyms/Alias

MTOR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000003413	ENSSSCP00000003699	ENSSSCT00000003786

Organism

Sus scrofa

Functional Description

Protein Length

2551

Protein Sequence
(FASTA)

MLGTGPAAAT TATTTSSNVS VLQQFASGLK SRNEETRAKA AKELQHYVTM ELREMSQEES 60

TRFYDQLNHH IFELVSSSDA NERKGGILAI ASLIGVEGGN ATRIGRFANY LRNLLPSNDP 120

VVMEMASKAI GRLAMAGDTF TAEYVEFEVK RALEWLGADR NEGRRHAAVL VLRELAVSVP 180

TFFFQQVQPF FDNIFVAVWD PKQAIREGAV AALRACLILT TQREPKEMQK PQWYRHTFEE 240

AEKGFDETLA KEKGMNRDDR IHGALLILNE LVRISSMEGE RLREEMEEIT QQQLVHDKYC 300

KDLMGFGTKP RHITPFTSFQ AVQPQQSNAL VGLLGYSSHQ GLLGFGASPS PAKSTLVESR 360

CCRDLMEEKF DQVCQWVLKC RNSKNSLIQM TILNLLPRLA AFRPSAFTDT QYLQDTMNHV 420

LSCVKKEKER TAAFQALGLL SVAVRSEFKV YLPRVLDIIR AALPPKDFAH KRQKAMQVDA 480

TVFTCISMLA RAMGPGIQQD IKELLEPMLA VGLSPALTAV LYDLSRQIPQ LKKDIQDGLL 540

KMLSLVLMHK PLRHPGMPKG LAHQLASPSL TTLPEASDVG SITLALRTLG SFEFEGHSLT 600

QFVRHCADHF LNSEHKEIRM EAARTCSRLL TPSVHLISGH AHVVSQTAVQ VVADVLSKLL 660

VVGITDPDPD IRYCVLASLD ERFDAHLAQA ENLQALFVAL NDQVFEIREL AICTVGRLSS 720

MNPAFVMPFL RKMLIQILTE LEHSGIGRIK EQSARMLGHL VSNAPRLIRP YMEPILKALI 780

LKLKDPDPDP NPGVINNVLA TIGELAQVSG LEMRKWVDEL FIIIMDMLQD SSLLAKRQVA 840

LWTLGQLVAS TGYVVEPYRK YPTLLEVLLN FLKTEQNQGT RREAIRVLGL LGALDPYKHK 900

VNIGMIDQSR DASAVSLSES KSSQDSSDYS TSEMLVNMGN LPLDEFYPAV SMVALMRIFR 960

DQSLSHHHTM VVQAITFIFK SLGLKCVQFL PQVMPTFLNV IRVCDGAIRE FLFQQLGMLV 1020

SFVKSHIRPY MDEIVTLMRE FWVMNTSIQS TIILLIEQIV VALGGEFKLY LPQLIPHMLR 1080

VFMHDNSPGR IVSIKLLAAI QLFGANLDDY LHLLLPPIVK LFDAPEVPLP SRKAALETVD 1140

RLTESLDFTD YASRIIHPIV RTLDQSPELR PTAMDTLSSL VFQLGKKYQI FIPMVNKVLV 1200

RHRINHQRYD ILICRIVKGY TLADEEEDPL IYQHRMLRSG QGDALASGPV ETGPMKKLHV 1260

STINLQKAWG AARRVSKDDW LEWLRRLSLE LLKDSSSPSL RSCWALAQAY NPMARDLFNA 1320

AFVSCWSELN EDQQDELIRS IELALTSQDI AEVTQTLLNL AEFMEHSDKG PLPLRDDNGI 1380

VLLGERAAKC RAYAKALHYK ELEFQKGPTP AILESLISIN NKLQQPEAAA GVLEYAMKHF 1440

GELEIQATWY EKLHEWEDAL VAYDKKMDTN KDDPELMLGR MRCLEALGEW GQLHQQCCEK 1500

WTLVNDETQA KMARMAAAAA WGLAGQWDSM EEYTCMIPRD THDGAFYRAV LALHQDLFSL 1560

AQQCIDKARD LLDAELTAMA GESYSRAYGA MVSCHMLSEL EEVIQYKLVP ERREIIRQIW 1620

WERLQGCQRI VEDWQRILMV RSLVVSPHED MRTWLKYASL CGKSGRLALA HKTLVLLLGV 1680

DPSRQLDHPL PTGHPQVTYA YMKNMWKSAR KIDAFQHMQH FVQTMQQQAQ RAIATEDQQH 1740

KQELHKLMAR CFLKLGEWQL NLQGINESTI PKVLQYYSAA TEHDRSWYKA WHAWAVMNFE 1800

AVLHYKHQNQ ARDEKKKLRH ASGANITNAA TAATTAATAT ATSTEGSNSE SEAESTENSP 1860

TPSPLQKKVT EDLSKTLLMY TVPAVQGFFR SISLSRGNNL QDTLRVLTLW FDYGHWPDVN 1920

EALVEGVKAI QIDTWLQVIP QLIARIDTPR PLVGRLIHQL LTDIGRYHPQ ALIYPLTVAS 1980

KSTTTARHNA ANKILKNMCE HSNTLVQQAM MVSEELIRVA ILWHEMWHEG LEEASRLYFG 2040

ERNVKGMFEV LEPLHAMMER GPQTLKETSF NQAYGRDLME AQEWCRKYMK SGNVKDLTQA 2100

WDLYYHVFRR ISKQLPQLTS LELQYVSPKL LMCRDLELAV PGTYDPNQPI IRIQSIAPSL 2160

QVITSKQRPR KLTLMGSNGH EFVFLLKGHE DLRQDERVMQ LFGLVNTLLA NDPTSLRKNL 2220

RSSIQRYAVI PLSTNSGLIG WVPHCDTLHA LIRDYREKKK ILLNIEHRIM LRMAPDYDHL 2280

TLMQKVEVFE HAVNNTAGDD LAKLLWLKSP SSEVWFDRRT NYTRSLAVMS MVGYILGLGD 2340

RHPSNLMLDR LSGKILHIDF GDCFEVAMTR EKFPEKIPFR LTRMLTNAME VTGLDGNYRI 2400

TCHTVMEVLR EHKDSVMAVL EAFVYDPLLN WRLMDTNTKG NKRSRTRTDS YSAGQSVEIL 2460

DGVELGEPAH KKTGTTVPES IHSFIGDGLV KPEALNKKAI QIINRVRDKL TGRDFSHDET 2520

LDVPTQVELL IKQATSHENL CQCYIGWCPF W 2551

Nucleotide Sequence
(FASTA)

ATGCTTGGAA CCGGACCTGC CGCCGCCACC ACAGCGACCA CCACTTCCAG CAACGTGAGC 60

GTCCTGCAGC AGTTTGCCAG TGGCCTGAAG AGCCGGAATG AGGAGACCAG GGCCAAAGCT 120

GCCAAGGAAC TCCAGCACTA TGTCACCATG GAGCTCCGAG AGATGAGTCA AGAGGAGTCT 180

ACTCGTTTCT ATGATCAGCT GAACCATCAC ATTTTTGAAC TGGTTTCCAG CTCAGATGCC 240

AATGAGAGGA AAGGCGGCAT CTTGGCCATA GCCAGCCTCA TAGGAGTGGA AGGCGGGAAT 300

GCCACCCGAA TCGGAAGATT TGCCAACTAT CTTCGGAACC TCCTCCCCTC CAATGACCCC 360

GTTGTCATGG AAATGGCATC CAAGGCCATT GGTCGCCTCG CCATGGCAGG AGACACTTTT 420

ACTGCAGAGT ATGTGGAGTT TGAGGTGAAG CGAGCCCTGG AGTGGCTGGG TGCTGACCGA 480

AACGAGGGCC GGAGACACGC AGCTGTCCTG GTCCTTCGTG AGCTGGCCGT CAGCGTCCCC 540

ACCTTCTTCT TCCAGCAAGT GCAGCCCTTC TTTGACAACA TTTTTGTGGC TGTGTGGGAC 600

CCCAAACAGG CCATCCGGGA GGGAGCTGTC GCCGCGCTCC GTGCCTGTCT GATCCTCACC 660

ACCCAGCGAG AGCCAAAGGA GATGCAGAAG CCGCAGTGGT ACAGGCACAC GTTCGAAGAA 720

GCAGAGAAAG GGTTTGACGA GACCTTGGCC AAGGAGAAGG GCATGAACCG GGACGACCGG 780

ATCCACGGAG CCTTGCTGAT CCTCAACGAG CTGGTCCGCA TCAGCAGCAT GGAGGGAGAG 840

CGCCTGAGAG AAGAAATGGA AGAAATCACA CAGCAGCAGT TGGTACATGA CAAGTACTGC 900

AAGGACCTCA TGGGCTTCGG GACGAAACCT CGTCACATCA CCCCCTTCAC CAGTTTCCAG 960

GCCGTGCAGC CCCAGCAGTC AAACGCCTTG GTGGGACTGC TGGGGTACAG CTCTCACCAA 1020

GGCCTCCTGG GGTTTGGGGC TTCCCCCAGC CCAGCCAAGT CCACGCTGGT GGAGAGTCGC 1080

TGTTGCAGAG ACTTGATGGA GGAGAAATTC GACCAGGTGT GCCAGTGGGT GCTGAAATGC 1140

AGGAATAGCA AGAACTCACT GATCCAAATG ACAATCCTTA ATTTGCTGCC CCGCTTGGCT 1200

GCCTTCCGAC CCTCTGCCTT CACAGATACG CAGTACCTCC AGGACACCAT GAACCATGTT 1260

CTAAGCTGCG TCAAGAAGGA GAAGGAACGG ACAGCAGCCT TCCAAGCCCT AGGGCTGCTT 1320

TCTGTGGCTG TGAGGTCTGA GTTCAAGGTC TATTTACCTC GTGTGCTGGA CATCATCCGA 1380

GCAGCCTTGC CTCCTAAGGA CTTTGCTCAT AAGAGACAGA AGGCCATGCA GGTGGACGCC 1440

ACAGTGTTCA CCTGCATCAG CATGCTGGCC CGGGCCATGG GGCCAGGCAT CCAGCAGGAT 1500

ATCAAGGAGC TGCTGGAGCC CATGCTGGCG GTGGGACTGA GCCCTGCCCT CACAGCTGTG 1560

CTCTACGACC TGAGCCGTCA GATTCCACAG CTGAAAAAGG ACATCCAGGA TGGGCTCCTG 1620

AAGATGCTGT CCCTGGTCCT TATGCACAAA CCCCTGCGGC ACCCGGGCAT GCCCAAGGGC 1680

CTGGCCCATC AGCTGGCTTC CCCCAGCCTC ACGACCCTCC CCGAGGCCAG TGACGTGGGC 1740

AGCATTACTC TTGCCCTCCG AACTCTCGGC AGTTTTGAAT TCGAAGGCCA CTCTCTGACC 1800

CAGTTCGTCC GCCACTGTGC GGATCACTTC CTGAACAGCG AGCACAAGGA GATCCGCATG 1860

GAAGCCGCCC GCACCTGCTC CCGCCTGCTT ACGCCCTCCG TCCACCTCAT CAGCGGCCAC 1920

GCTCACGTGG TCAGCCAGAC CGCAGTGCAG GTGGTGGCGG ATGTGCTCAG CAAGCTGCTC 1980

GTGGTTGGGA TAACCGATCC TGACCCCGAC ATCCGCTACT GCGTCTTGGC GTCCCTGGAT 2040

GAGCGCTTTG ACGCGCACCT GGCCCAGGCA GAGAATCTGC AGGCCCTGTT TGTGGCCCTG 2100

AATGACCAGG TGTTTGAGAT CCGGGAGCTG GCCATCTGCA CCGTGGGCCG GCTCAGCAGC 2160

ATGAACCCAG CCTTCGTCAT GCCCTTCCTG CGCAAGATGC TCATCCAGAT TTTGACGGAG 2220

CTGGAGCACA GTGGCATCGG AAGAATCAAG GAGCAGAGTG CCCGCATGCT GGGCCACCTG 2280

GTCTCCAACG CCCCCCGACT CATCCGCCCC TACATGGAGC CCATTCTCAA GGCCTTAATT 2340

TTGAAACTGA AAGATCCAGA CCCTGATCCA AACCCCGGAG TGATCAACAA CGTCTTGGCT 2400

ACAATCGGAG AGCTGGCTCA GGTCAGTGGC CTAGAAATGA GGAAGTGGGT GGATGAACTT 2460

TTTATTATCA TCATGGACAT GCTCCAGGAC TCCTCTCTGT TGGCCAAAAG GCAGGTGGCC 2520

CTGTGGACTC TGGGACAGCT GGTGGCCAGC ACTGGCTATG TGGTGGAGCC CTACAGGAAG 2580

TACCCCACAT TGCTGGAGGT GCTGCTGAAT TTCCTGAAGA CTGAGCAGAA CCAGGGTACA 2640

CGGCGAGAGG CTATCCGCGT GTTAGGGCTC TTGGGGGCCT TGGACCCCTA CAAGCACAAA 2700

GTGAACATTG GCATGATCGA CCAGTCCCGG GACGCTTCTG CCGTCAGCCT GTCAGAATCC 2760

AAGTCAAGTC AGGACTCCTC CGACTACAGC ACCAGTGAGA TGCTGGTCAA CATGGGGAAC 2820

CTGCCCCTGG ACGAGTTCTA CCCGGCCGTG TCCATGGTGG CCCTGATGCG GATCTTCCGA 2880

GACCAGTCCC TCTCCCACCA CCACACCATG GTCGTCCAGG CCATCACCTT CATCTTCAAG 2940

TCCCTGGGGC TCAAGTGTGT GCAGTTCCTG CCCCAGGTCA TGCCCACGTT CCTGAACGTC 3000

ATTCGGGTTT GCGACGGGGC CATCCGGGAA TTTCTGTTCC AGCAACTGGG GATGCTGGTG 3060

TCCTTTGTGA AGAGCCACAT CAGACCTTAT ATGGATGAGA TTGTCACCCT CATGAGAGAA 3120

TTCTGGGTCA TGAACACCTC CATCCAGAGC ACCATCATTC TTCTCATTGA GCAGATTGTG 3180

GTAGCTCTTG GGGGCGAGTT TAAGCTCTAC CTGCCCCAGC TGATCCCACA CATGCTCCGA 3240

GTCTTCATGC ATGACAACAG CCCAGGCCGC ATCGTCTCCA TCAAGTTGCT GGCCGCAATC 3300

CAGCTGTTTG GCGCCAACCT GGATGACTAT CTGCATTTGT TGTTGCCCCC TATTGTGAAG 3360

TTGTTTGATG CCCCTGAAGT TCCATTGCCA TCTCGAAAGG CAGCGCTAGA GACAGTGGAC 3420

CGCCTGACGG AGTCCCTGGA TTTCACTGAC TATGCCTCTC GGATCATCCA CCCGATTGTG 3480

CGAACCCTGG ACCAGAGCCC AGAACTCCGT CCCACGGCCA TGGACACGCT CTCTTCGCTC 3540

GTTTTCCAGC TGGGGAAGAA GTACCAAATT TTCATTCCCA TGGTGAACAA AGTTCTGGTG 3600

CGACATCGCA TCAACCATCA GCGCTACGAT ATTCTCATCT GCAGGATTGT CAAGGGCTAC 3660

ACCCTTGCCG ACGAAGAAGA GGACCCTTTG ATTTACCAGC ATCGGATGCT AAGAAGTGGC 3720

CAAGGGGACG CACTGGCTAG TGGACCAGTA GAGACGGGAC CCATGAAGAA ATTGCACGTC 3780

AGCACCATCA ACCTCCAAAA GGCCTGGGGA GCTGCCAGAA GGGTCTCCAA AGATGACTGG 3840

TTGGAATGGC TGAGGCGGCT GAGCCTGGAG CTGCTGAAGG ACTCCTCGTC CCCATCCCTG 3900

CGCTCGTGCT GGGCCCTGGC TCAGGCCTAC AACCCGATGG CCAGGGATCT CTTCAACGCG 3960

GCCTTTGTGT CCTGCTGGTC TGAGCTGAAC GAAGACCAGC AGGATGAGCT CATCAGAAGC 4020

ATCGAGCTGG CCCTCACCTC CCAGGACATC GCTGAAGTCA CACAAACGCT CTTAAACTTG 4080

GCCGAATTCA TGGAACACAG TGACAAGGGC CCCCTGCCGT TGAGAGATGA CAATGGCATT 4140

GTTCTGCTGG GCGAGAGGGC CGCCAAGTGT CGAGCATACG CCAAGGCGCT GCACTACAAA 4200

GAACTGGAGT TCCAGAAGGG CCCCACCCCC GCCATCCTGG AGTCTCTCAT CAGCATCAAT 4260

AATAAGCTAC AACAGCCAGA GGCAGCTGCC GGGGTCTTGG AGTATGCCAT GAAGCACTTT 4320

GGAGAGCTGG AGATCCAGGC TACCTGGTAC GAGAAACTGC ATGAGTGGGA GGATGCCCTG 4380

GTGGCCTACG ACAAGAAGAT GGACACCAAC AAGGACGACC CGGAGCTGAT GCTGGGCCGC 4440

ATGCGCTGCC TCGAGGCCTT GGGGGAATGG GGGCAGCTGC ACCAGCAGTG CTGTGAGAAG 4500

TGGACCCTGG TGAATGACGA AACCCAAGCC AAGATGGCCC GGATGGCTGC TGCGGCTGCC 4560

TGGGGTCTCG CAGGTCAGTG GGACAGCATG GAGGAGTACA CCTGTATGAT CCCTCGGGAC 4620

ACCCACGATG GGGCGTTTTA TAGAGCCGTG CTGGCCCTGC ATCAGGACCT CTTCTCCTTG 4680

GCCCAACAGT GCATCGACAA AGCCCGGGAC CTGCTGGACG CCGAGCTGAC TGCGATGGCA 4740

GGAGAGAGCT ACAGCCGGGC CTACGGGGCC ATGGTCTCCT GCCACATGCT CTCCGAGCTG 4800

GAGGAGGTTA TCCAGTACAA ACTTGTCCCC GAGCGACGAG AGATCATCCG CCAGATCTGG 4860

TGGGAGAGAC TACAGGGCTG CCAGCGGATC GTGGAGGACT GGCAGAGGAT CCTCATGGTG 4920

CGCTCGCTCG TGGTCAGCCC TCACGAGGAC ATGAGGACAT GGCTCAAGTA CGCGAGCCTG 4980

TGCGGCAAGA GCGGCAGGCT GGCTCTTGCT CACAAGACCT TGGTGCTGCT CCTGGGAGTG 5040

GATCCGTCTC GGCAGCTCGA CCACCCTCTG CCCACAGGCC ACCCCCAGGT GACCTACGCC 5100

TACATGAAGA ACATGTGGAA GAGCGCCCGC AAGATCGATG CCTTCCAGCA CATGCAGCAC 5160

TTTGTTCAGA CCATGCAGCA GCAAGCCCAA CGCGCCATCG CCACTGAGGA CCAGCAGCAC 5220

AAGCAGGAGC TGCACAAGCT CATGGCCCGA TGTTTCCTGA AACTTGGAGA GTGGCAGCTG 5280

AACCTTCAGG GGATCAACGA GAGCACGATC CCTAAAGTCC TGCAGTACTA CAGCGCCGCC 5340

ACGGAGCACG ACCGTAGCTG GTACAAGGCC TGGCACGCGT GGGCAGTGAT GAACTTCGAA 5400

GCTGTGCTCC ATTACAAACA TCAGAACCAA GCCCGCGACG AGAAGAAGAA GCTGCGCCAC 5460

GCCAGCGGGG CCAACATCAC TAACGCAGCC ACCGCAGCCA CCACAGCGGC CACCGCCACG 5520

GCCACCAGCA CTGAGGGCAG CAACAGCGAG AGCGAGGCCG AGAGCACTGA GAACAGCCCC 5580

ACCCCGTCTC CTCTGCAGAA GAAGGTCACT GAGGATTTGT CCAAAACCCT CTTGATGTAC 5640

ACCGTCCCTG CTGTCCAGGG TTTCTTCCGT TCCATCTCTT TGTCACGAGG CAACAACCTC 5700

CAGGACACAC TCAGAGTCCT CACCTTATGG TTTGATTATG GGCACTGGCC GGATGTAAAC 5760

GAAGCCTTAG TGGAAGGGGT GAAAGCGATC CAGATTGATA CCTGGTTACA GGTCATACCT 5820

CAGCTCATTG CAAGAATCGA TACGCCCAGG CCCTTGGTGG GGCGTCTCAT TCACCAGCTT 5880

CTCACAGACA TCGGTCGGTA CCACCCCCAG GCCCTCATCT ACCCCCTGAC GGTGGCGTCT 5940

AAGTCCACCA CCACCGCCCG GCACAACGCG GCCAACAAGA TCCTGAAGAA CATGTGTGAG 6000

CACAGCAACA CCCTGGTGCA GCAGGCCATG ATGGTGAGCG AGGAGCTGAT CCGAGTGGCC 6060

ATCCTCTGGC ACGAGATGTG GCACGAAGGC CTGGAAGAGG CGTCTCGCTT GTACTTCGGG 6120

GAGAGGAACG TGAAAGGCAT GTTCGAGGTG CTGGAGCCCC TGCACGCCAT GATGGAGCGG 6180

GGACCCCAGA CCCTGAAGGA GACCTCCTTT AACCAGGCAT ACGGTCGAGA CTTAATGGAG 6240

GCCCAGGAGT GGTGCAGGAA GTACATGAAA TCCGGGAACG TCAAGGACCT CACCCAGGCC 6300

TGGGACCTCT ATTACCACGT GTTCAGGCGC ATCTCGAAGC AGCTGCCGCA GCTCACATCC 6360

CTAGAGCTGC AGTATGTTTC CCCCAAACTC CTGATGTGCC GGGACCTTGA ATTGGCTGTG 6420

CCAGGAACCT ATGACCCCAA CCAGCCCATC ATTCGCATTC AGTCCATAGC GCCGTCTCTG 6480

CAGGTCATCA CGTCCAAGCA GAGGCCCCGG AAGCTGACAC TTATGGGCAG CAACGGCCAC 6540

GAGTTCGTCT TCCTCCTGAA GGGCCACGAA GACCTGCGGC AGGACGAGCG CGTCATGCAG 6600

CTCTTCGGCC TGGTCAACAC CCTTTTGGCC AACGACCCAA CGTCTCTCCG CAAGAACCTC 6660

AGGTCCAGCA TCCAGAGGTA CGCCGTCATC CCCTTATCCA CCAACTCGGG CCTCATCGGC 6720

TGGGTCCCCC ACTGTGACAC ACTGCACGCC CTCATCCGGG ACTACAGGGA GAAGAAGAAG 6780

ATCCTTCTCA ACATCGAGCA TCGCATCATG CTGCGGATGG CTCCAGACTA CGACCACCTG 6840

ACCCTGATGC AGAAGGTTGA GGTGTTCGAG CACGCCGTCA ACAACACCGC CGGCGATGAC 6900

CTGGCCAAGC TGCTGTGGCT GAAAAGCCCC AGCTCCGAGG TGTGGTTTGA TCGAAGAACC 6960

AACTACACTC GCTCTTTAGC AGTCATGTCC ATGGTTGGGT ATATTTTGGG CCTGGGCGAT 7020

AGACACCCAT CTAACCTGAT GCTGGACCGG CTGAGCGGGA AGATCCTGCA CATTGACTTT 7080

GGGGACTGCT TTGAGGTTGC TATGACCAGA GAGAAGTTCC CAGAGAAGAT TCCATTTAGA 7140

CTAACGAGAA TGTTGACCAA TGCTATGGAG GTCACTGGTC TGGATGGCAA CTACAGGATC 7200

ACGTGCCACA CGGTCATGGA AGTGCTTCGG GAACACAAGG ACAGCGTCAT GGCCGTGCTG 7260

GAAGCCTTCG TCTATGACCC CTTACTGAAC TGGAGGCTGA TGGACACAAA CACCAAAGGT 7320

AACAAGCGAT CGCGCACAAG GACGGATTCC TACTCTGCCG GCCAGTCAGT AGAAATTTTG 7380

GATGGTGTGG AACTTGGGGA ACCAGCCCAT AAGAAAACGG GGACCACAGT GCCAGAATCT 7440

ATTCATTCGT TCATTGGAGA TGGTTTGGTG AAACCGGAGG CCCTAAATAA GAAAGCTATT 7500

CAGATTATTA ACAGGGTTCG AGATAAGCTC ACTGGTCGGG ACTTTTCTCA TGATGAAACC 7560

TTGGATGTCC CAACGCAAGT GGAGCTGCTC ATCAAACAAG CCACATCCCA TGAAAACCTC 7620

TGCCAGTGCT ACATCGGCTG GTGTCCTTTC TGGTAA 7656

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i+++++++++++skq+p+kl+l+Gs+g+e+++L+kg+eDlrqderv+qlf+lvNtlLa+d

Q: 2153  IQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLAND  2212

         899*********************************************************

S: 61    ketsrrkL..kirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyryk  118

         +++ r++L  +i++y+V+plst+sgli+wv+++++L++l+++++ekk++ll+

Q: 2213  PTSLRKNLrsSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLN-------I  2265

         ********5569***************************************9.......9

S: 119   dlstvqarkpklkhlkls..levfkevlenlvpkdllkklllekfpspeewfelrkaytr  176

         +++++ +++p+++hl+l+  +evf+++++n ++ d l+kll+ k+ps+e+wf++r++ytr

Q: 2266  EHRIMLRMAPDYDHLTLMqkVEVFEHAVNN-TAGDDLAKLLWLKSPSSEVWFDRRTNYTR  2324

         ******************************.999**************************

S: 177   slAvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrn  236

         slAv+s+vgyiLgLgdrh++nl++d+ +g+++hidfg +fe a+t++k+pek+PFRLTr+

Q: 2325  SLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRM  2384

         ************************************************************

S: 237   ivnalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkkkkktsketeee  296

         ++na++vtg++G++r++c++v++vlre+k++++++Le+f+ydpl++w+ +++++k+++++

Q: 2385  LTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRS  2444

         ************************************************************

S: 297   laekakaealkikkllskvekaenavatrdlllle  331

         ++++++++a +++++l++ve +e+a+++++++++e

Q: 2445  RTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPE  2479

         ******************************99987

Domain Sequence
(FASTA)

IQSIAPSLQV ITSKQRPRKL TLMGSNGHEF VFLLKGHEDL RQDERVMQLF GLVNTLLAND 60

PTSLRKNLRS SIQRYAVIPL STNSGLIGWV PHCDTLHALI RDYREKKKIL LNIEHRIMLR 120

MAPDYDHLTL MQKVEVFEHA VNNTAGDDLA KLLWLKSPSS EVWFDRRTNY TRSLAVMSMV 180

GYILGLGDRH PSNLMLDRLS GKILHIDFGD CFEVAMTREK FPEKIPFRLT RMLTNAMEVT 240

GLDGNYRITC HTVMEVLREH KDSVMAVLEA FVYDPLLNWR LMDTNTKGNK RSRTRTDSYS 300

AGQSVEILDG VELGEPAHKK TGTTVPE 327

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005829	; C:cytosol
GO:0012505	; C:endomembrane system
GO:0005764	; C:lysosome
GO:0016020	; C:membrane
GO:0016605	; C:PML body
GO:0005524	; F:ATP binding
GO:0008144	; F:drug binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0043022	; F:ribosome binding
GO:0001030	; F:RNA polymerase III type 1 promoter DNA binding
GO:0001031	; F:RNA polymerase III type 2 promoter DNA binding
GO:0001032	; F:RNA polymerase III type 3 promoter DNA binding
GO:0071456	; P:cellular response to hypoxia
GO:0031669	; P:cellular response to nutrient levels
GO:0007281	; P:germ cell development
GO:0045792	; P:negative regulation of cell size
GO:0016242	; P:negative regulation of macroautophagy
GO:0051534	; P:negative regulation of NFAT protein import into nucleus
GO:0018105	; P:peptidyl-serine phosphorylation
GO:0018107	; P:peptidyl-threonine phosphorylation
GO:0030838	; P:positive regulation of actin filament polymerization
GO:0010592	; P:positive regulation of lamellipodium assembly
GO:0046889	; P:positive regulation of lipid biosynthetic process
GO:0050731	; P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0051496	; P:positive regulation of stress fiber assembly
GO:0045945	; P:positive regulation of transcription from RNA polymerase III promoter
GO:0045859	; P:regulation of protein kinase activity
GO:0032314	; P:regulation of Rac GTPase activity
GO:0043200	; P:response to amino acid stimulus
GO:0032868	; P:response to insulin stimulus
GO:0031529	; P:ruffle organization
GO:0031929	; P:TOR signaling cascade

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR024585	; DUF3385_TOR.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR009076	; Rapamycin-bd_dom.
IPR026683	; TOR/Smg1.

Pfam

PF11865	; DUF3385; 1.
PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08771	; Rapamycin_bind; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013