EPS-SUS-00019

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-SUS-00019

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	207.7	3.3E-61	659	904	246

Status

Unreviewed

Ensembl Protein

ENSSSCP00000005267

UniProt Accession

F1SMW1;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP1

Gene Synonyms/Alias

PHLPP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000004896	ENSSSCP00000005267	ENSSSCT00000005402

Organism

Sus scrofa

Functional Description

Protein Length

1192

Protein Sequence
(FASTA)

LKCLLVFVAG KPHSIGSSER IQLSGMYNVR KGKMQLPVNR WTRRQVILCG TCLIVSSVKD 60

SLTGKMHVLP LIGGKVEEVK KHQHCLAFSS SGPQSQTYYI CFDTFTEYLR WLRQVSKVAS 120

QRISSVDLSC CSLEHLPANL FYSQDLTHLN LKQNFLRQNP SLPTARGLSE LQRFTKLKSL 180

NLSNNHLGDF PLAVCNIPTL AELNVSCNAL QTVPAAVGVM HNLQTFLLDG NFLQTLPAEL 240

ENIHQLSYLG LSFNEFTDIP EVLEKLTAVD KLCMSGNCME TLRLQALRKM PHIKHVDLRL 300

NLIRKLIADE VDFLPHVTQL DLRDNKLGDL DAMVFNNIEV LHCERNQLVT LNICGYFLKA 360

LYASSNELVQ LDVYPVPNYL SYMDVSRNRL ENVPEWVCEG RKLEVLDIGH NQICELPASL 420

FCNSSLRKLL AGHNQLTRLP ERLERTSVEV LDVQHNQLLE LPPNLLMKAD SLRFLNASAN 480

KLETLPPATL SEETNSILQE LYLTNNNLTD KCVHLLTGHP RLKILHMAYN RLQSFPASKM 540

AKLEELEEID ISGNKLKAIP TTIMNCRRMH TVIAHSNCIE VFPEVMQLPE IKCVDLSCNE 600

LSEVTLPENL PPKLQELDLT GNPRLALDHK TLELLNNIRC FKIDQPSAGD ASGAPAVWSH 660

GYTEASGVKN KLCVAALSVN NFCDNREALY GVFDGDRNVE VPYLLQCTMS DILAEELQKT 720

KNEEEYMVNT FIVMQRKLGT AGQKLGGAAV LCHIKHDPVD PGGPFTLTSA NVGKCQTVLC 780

RNGKPLPLSR SYLMSSEEEL KRIKRHKAII TEDGKVNGVT ESTRILGYTF LHPSVVPRPH 840

VQSVPLTPQD EFFILGSKGL WDSLSIEEAV GAVRNVPDAL AAAKKLCTLA QSYGCHDSIS 900

AVVVQLSVTE DSFCCCELSA GGAPPPSPGI FPPSVSMVIK DRPADGLGVP SSSSGMASEI 960

SSELSTSEMS SEVGSTASDE PPGALAESGP AYPSEPRCTL HPVCLSNSFQ RQLSSATFSS 1020

AFSDNGLDSD DEEPIEGVFS NGSRVEVEVD IHCGRAKEKQ QHLLQVPAEA SDEGIVISAN 1080

EDESGLPRKA DLATVGTMGR RRANGSVAPQ ERSHNVIEVA TDAPLRKPGG YFAAPAQPDP 1140

DDQFIIPPEL EEEVKEIMKH HQQQQPPPQL HLQQPQRQCP VDQLPDYCDT PL 1192

Nucleotide Sequence
(FASTA)

CTAAAATGTT TGCTTGTGTT TGTTGCAGGA AAACCTCACA GCATCGGTAG CTCTGAACGG 60

ATTCAGCTCT CAGGAATGTA TAATGTCCGT AAAGGCAAGA TGCAGTTGCC AGTGAACCGA 120

TGGACCAGAC GCCAAGTCAT CCTGTGTGGG ACCTGTCTAA TAGTATCATC TGTGAAAGAC 180

AGCTTGACCG GAAAGATGCA CGTTCTGCCA CTAATTGGGG GAAAAGTAGA AGAAGTGAAA 240

AAGCACCAGC ACTGCTTAGC CTTTAGCTCC TCTGGACCCC AAAGCCAGAC TTACTACATT 300

TGTTTTGATA CCTTCACAGA GTATTTAAGG TGGCTTCGAC AAGTCTCCAA GGTTGCATCA 360

CAGCGTATTA GCTCAGTGGA CCTCTCGTGT TGTAGCCTGG AGCATCTGCC TGCCAACCTC 420

TTCTACAGCC AAGACCTTAC TCATCTCAAT TTAAAACAAA ACTTCCTAAG GCAGAATCCC 480

AGTCTACCAA CTGCCAGGGG CCTCAGCGAA CTGCAGAGGT TCACCAAGTT GAAGAGTCTT 540

AACCTTTCCA ATAATCATTT AGGGGACTTC CCATTAGCAG TCTGCAATAT TCCAACCCTG 600

GCCGAGCTGA ATGTGTCCTG CAATGCCCTG CAAACAGTGC CAGCCGCCGT CGGAGTCATG 660

CACAACTTAC AGACATTTTT GTTGGATGGA AACTTTCTTC AGACTCTTCC TGCTGAGTTG 720

GAGAACATAC ATCAGCTTAG TTATCTTGGT CTTTCTTTCA ATGAATTCAC TGACATTCCG 780

GAGGTATTGG AGAAATTGAC TGCTGTGGAT AAGCTTTGTA TGTCTGGAAA CTGTATGGAG 840

ACTCTTAGGC TACAGGCTTT ACGAAAAATG CCTCACATTA AACATGTGGA CCTAAGACTG 900

AACCTAATTA GGAAGCTAAT AGCAGATGAA GTGGACTTTC TCCCTCATGT CACTCAGCTT 960

GATTTGCGTG ACAATAAGCT TGGTGATCTG GATGCTATGG TTTTCAACAA TATTGAAGTT 1020

TTACACTGTG AAAGGAATCA ACTGGTGACA TTAAACATCT GTGGCTATTT CCTAAAAGCA 1080

CTCTATGCCT CTTCTAATGA GCTTGTCCAA CTCGATGTTT ACCCAGTTCC GAATTATCTA 1140

TCCTATATGG ATGTTTCAAG GAACCGCTTA GAAAACGTGC CTGAATGGGT ATGTGAAGGC 1200

CGAAAGCTAG AAGTTTTGGA TATTGGCCAT AATCAAATAT GTGAGCTTCC TGCAAGCTTA 1260

TTTTGTAATA GTAGTCTCCG GAAACTACTG GCAGGACACA ACCAGCTGAC GAGGCTTCCT 1320

GAAAGGCTGG AAAGAACCTC AGTGGAGGTC TTGGATGTAC AACACAACCA GCTCCTGGAG 1380

CTGCCACCCA ACCTTCTGAT GAAGGCCGAC AGCCTGAGAT TCCTGAATGC ATCGGCAAAC 1440

AAACTGGAAA CGCTTCCTCC AGCCACACTT TCTGAAGAGA CAAACAGCAT CTTACAGGAG 1500

TTGTATTTGA CAAATAACAA CCTCACAGAT AAATGTGTGC ACTTGTTAAC GGGACATCCC 1560

CGTCTGAAGA TTCTTCACAT GGCCTATAAC CGACTTCAGA GTTTTCCAGC AAGTAAAATG 1620

GCAAAGCTAG AGGAACTTGA AGAAATCGAC ATCAGTGGGA ATAAACTGAA AGCCATCCCG 1680

ACAACGATCA TGAATTGCAG GCGCATGCAC ACAGTGATCG CGCACTCTAA CTGCATTGAA 1740

GTCTTTCCTG AAGTTATGCA GCTCCCAGAA ATTAAGTGTG TCGACCTGAG CTGTAATGAA 1800

CTAAGTGAAG TCACTTTACC AGAAAACCTG CCTCCAAAAC TTCAAGAACT AGACCTGACT 1860

GGAAACCCCC GACTTGCCCT TGATCACAAA ACCTTGGAGC TGCTGAATAA TATCCGCTGT 1920

TTCAAGATTG ATCAGCCTTC AGCAGGAGAT GCATCTGGAG CCCCAGCTGT ATGGAGCCAT 1980

GGCTACACTG AAGCTTCAGG GGTAAAAAAC AAGTTATGTG TTGCAGCCCT GTCGGTGAAC 2040

AATTTCTGTG ACAACCGGGA GGCCCTGTAT GGTGTGTTTG ATGGAGACCG GAATGTGGAG 2100

GTGCCCTACC TTCTCCAGTG CACTATGAGT GACATTTTGG CAGAAGAGCT GCAGAAAACA 2160

AAAAACGAAG AAGAATACAT GGTCAATACG TTCATTGTTA TGCAAAGGAA GCTTGGAACT 2220

GCTGGGCAGA AACTTGGAGG TGCTGCTGTC CTGTGTCATA TCAAGCATGA TCCTGTGGAC 2280

CCAGGAGGAC CCTTCACCTT GACCTCTGCT AACGTGGGCA AGTGTCAAAC AGTTCTCTGT 2340

CGGAATGGGA AGCCGCTGCC TCTGTCCAGA TCGTATCTCA TGAGCTCTGA GGAAGAACTG 2400

AAGAGAATCA AGCGGCACAA GGCCATTATC ACTGAGGATG GCAAGGTGAA CGGAGTGACG 2460

GAGTCCACAC GCATCCTAGG CTACACCTTC CTCCACCCCA GCGTGGTGCC CCGCCCCCAC 2520

GTGCAGTCGG TGCCCCTTAC CCCGCAGGAC GAGTTCTTCA TCCTGGGCAG CAAGGGCCTG 2580

TGGGACAGCC TGTCCATCGA GGAGGCCGTG GGGGCCGTGC GCAACGTGCC CGATGCCCTG 2640

GCCGCTGCCA AGAAGCTGTG CACGCTGGCG CAGAGCTACG GCTGCCACGA CAGCATCAGC 2700

GCTGTGGTGG TGCAGCTCAG CGTTACCGAG GACAGCTTCT GCTGCTGCGA GCTGAGCGCC 2760

GGTGGGGCCC CGCCGCCCAG CCCCGGCATC TTCCCGCCCT CCGTCAGCAT GGTGATAAAG 2820

GACCGGCCAG CCGATGGGCT GGGCGTGCCG TCGTCCAGCA GCGGCATGGC CTCGGAGATC 2880

AGCAGCGAGC TCTCCACGTC TGAGATGAGC AGCGAGGTGG GCTCCACCGC CTCTGACGAG 2940

CCGCCGGGTG CCCTGGCCGA GAGCGGCCCT GCCTATCCCA GTGAGCCGCG CTGCACGCTG 3000

CACCCTGTCT GCTTATCCAA CTCCTTCCAG CGCCAGCTGT CCAGCGCCAC TTTCTCCAGC 3060

GCCTTCTCCG ACAACGGCCT GGACAGCGAT GACGAAGAGC CCATCGAGGG TGTCTTCAGC 3120

AATGGCAGCC GGGTGGAGGT GGAGGTGGAC ATCCACTGCG GCCGGGCCAA GGAAAAGCAG 3180

CAACACCTGC TCCAGGTGCC TGCCGAGGCC AGTGACGAAG GTATCGTCAT CAGTGCAAAC 3240

GAGGATGAGT CAGGGCTGCC CAGGAAGGCT GACTTGGCCA CCGTGGGGAC CATGGGGCGG 3300

CGCAGGGCGA ACGGCTCCGT GGCACCCCAG GAGAGGAGCC ACAACGTGAT TGAGGTGGCC 3360

ACGGACGCAC CGCTCCGGAA GCCTGGAGGT TATTTTGCAG CCCCAGCTCA GCCAGATCCT 3420

GACGACCAGT TCATCATTCC CCCAGAGCTG GAGGAGGAGG TCAAAGAGAT CATGAAACAC 3480

CACCAGCAGC AGCAGCCCCC ACCACAGCTC CACCTGCAGC AGCCGCAGCG GCAGTGCCCG 3540

GTGGACCAGC TGCCAGACTA CTGTGACACA CCACTATGA 3579

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 659   SHGYTEASGVKNKLCVAALSVNNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  713

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 714   AEELQ----KTKNEEEYMVNTFIVMQRKL------GTAGQKLGGAAVLCHIKHDpvdpgg  763

         ***99....999*****************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ + +s+e+El+Ri+++++ ++++   +v+Gv++

Q: 764   pfTLTSANVGKCQTVLCRNGKPLPLSRSYLMSSEEELKRIKRHKAIITEDG--KVNGVTE  821

         ********************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s++lt++def+iL+s+Glwd +s eeav +vr+v +

Q: 822   STRILGYTFLHPSVVPRPHVQSVPLTPQDEFFILGSKGLWDSLSIEEAVGAVRNVPD---  878

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL++la+++g++d++sa+vv

Q: 879   -ALAAAKKLCTLAQSYGCHDSISAVVV  904

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS VNNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKNEEEYMV NTFIVMQRKL GTAGQKLGGA AVLCHIKHDP VDPGGPFTLT SANVGKCQTV 120

LCRNGKPLPL SRSYLMSSEE ELKRIKRHKA IITEDGKVNG VTESTRILGY TFLHPSVVPR 180

PHVQSVPLTP QDEFFILGSK GLWDSLSIEE AVGAVRNVPD ALAAAKKLCT LAQSYGCHDS 240

ISAVVV 246

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>