EPS-SUS-00009

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-SUS-00009

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	150.9	2.7E-44	136	281	146

Status

Unreviewed

Ensembl Protein

ENSSSCP00000006730

UniProt Accession

F1S254;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100737362

Gene Synonyms/Alias

LOC100737362;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000006311	ENSSSCP00000006730	ENSSSCT00000006918

Organism

Sus scrofa

Functional Description

Protein Length

1156

Protein Sequence
(FASTA)

QIVMATSGDP EEEQVVPSEE DEADVRAVQA RYLRSPSPSQ YSIVSDAETE SIFMDPIHLS 60

SAVAAKQIIN EELKPRGIKA EAECPGMLES AEQLLVEDLY NRVREKMDDT SLYNTPCIMD 120

LQRALVQDRQ EAPWNEVDEV WPNVFIAEKS VAVNKGRLKR LGITHILNAA HGTGVYTGPE 180

FYTGLEIQYL GVEVDDFPEV NISQHFRKAA EFLDEALLTY RGKVLVSSEM GISRSAVLVV 240

AYLMIFHNMA ILEALMTVRK KRPIYPNDGF LKQLRELNEK LMEEREEDFG GAGGAEEAEE 300

GEDAGSTVGA RVYALTVEEE DDVTSHLSGS SLGKASRASK PPTLIDEEEE EKLYEAWKKG 360

RGLPTGKVPQ GRDSRGEEEA EDEDVERIIR EWQSRNERYQ AEGHRRWDRE EEAEEEESDT 420

GSFVRRRRKH TLSESSTSES VSSRDIRVLK QQLEMSSQNR GGRHRSDSVS TESTWDMWNQ 480

RLLEIEKEAS RRYHSRSKRE EVDSSSEVGS GMREDDEQSV SSEASSFYNF CSRNKDKLTA 540

LERWKIKRIQ FGFHKKDSEA GDGSSEQDAE EVEGEKKNPS DVNLSAYQAW KLKHQKKVGS 600

ENKEEVVELS KGEDSALAKK RQRRLELLER SRQTLQESQS MGSWEADSSA ASGSIPLSAF 660

WSAAPSVSAD GDTASVLSTQ SHSSHPSQAL RNVGGCLASA PTTPLPNLPV GPGDTISIAS 720

IQNWIANVVS ETLAQKQNEI LLLSRSPSVA SMKVAPAASC LGDDQVSMLS GQSSSSLGGS 780

LLPQSQARPS SDTQSVLSSH TTQSSRAEGT GSKVRGTSKP IYSLFADNVD LRELGRKEKE 840

MQMELKEKMS EYKMEKLASD NKRSSLFKKK KGRGDEDDDV GDWDEDTDSA IGSFRYSSRS 900

NSQKPETDTA SSLAVSDSYG SGSRAGKEMD SSINKWLSGL RTEEKSPPQS DWSGSSRGKC 960

TRSSLLRETE SKSSSYKFSK SQSEEQDTSS YHEANGNSVR STSKFSASST REGREMHTFS 1020

RSTFSETSSS REESPEPYFF RRTPEPSEGE ESPEPRRPNW ARPRDWEDVE ESSKSDFSEF 1080

GAKRKFTQSF MRSEEEGEKE RMEKREEGRF ASGRRSQYRR STDREEEEEM DDEAIIAAWR 1140

RRQEETRTKL QRRRED 1156

Nucleotide Sequence
(FASTA)

CAGATTGTCA TGGCGACCAG TGGGGACCCA GAAGAGGAGC AGGTGGTCCC AAGTGAAGAG 60

GATGAAGCTG ACGTGAGGGC TGTGCAGGCT CGGTACCTCC GGAGCCCCTC TCCTAGCCAA 120

TACTCAATTG TCTCAGACGC GGAAACAGAA AGTATTTTCA TGGATCCCAT TCACCTCTCC 180

TCAGCTGTTG CAGCTAAACA GATCATCAAT GAAGAACTCA AGCCTCGGGG CATCAAAGCC 240

GAGGCAGAGT GTCCAGGCAT GCTGGAGTCT GCCGAGCAGC TGCTGGTGGA GGACCTGTAC 300

AACCGTGTCA GGGAGAAGAT GGATGACACC AGCCTGTACA ACACCCCCTG CATCATGGAC 360

CTGCAGCGGG CCTTGGTCCA AGACCGCCAA GAGGCCCCCT GGAATGAGGT GGATGAGGTC 420

TGGCCCAACG TCTTCATAGC AGAGAAGAGT GTGGCTGTGA ACAAGGGGAG GCTGAAGAGG 480

CTGGGAATTA CCCATATCCT GAATGCTGCT CATGGCACCG GTGTCTACAC TGGGCCTGAA 540

TTCTATACTG GCCTGGAGAT CCAGTACCTG GGTGTGGAGG TTGATGACTT CCCTGAGGTG 600

AACATCTCCC AGCATTTCCG GAAGGCGGCA GAGTTCCTGG ACGAAGCCCT GCTGACCTAC 660

AGAGGGAAAG TCCTGGTCAG CAGTGAAATG GGCATCAGCC GCTCGGCAGT GCTGGTGGTT 720

GCCTACCTAA TGATCTTCCA CAACATGGCC ATCCTGGAGG CCCTGATGAC TGTGCGCAAG 780

AAGCGGCCCA TCTACCCCAA TGACGGCTTC CTGAAGCAGC TCCGGGAGCT TAACGAGAAG 840

CTGATGGAGG AGCGAGAAGA GGACTTCGGC GGGGCAGGGG GAGCGGAGGA GGCGGAGGAG 900

GGTGAGGACG CCGGGAGCAC AGTCGGGGCC AGAGTGTACG CCCTCACCGT GGAGGAGGAG 960

GATGATGTCA CCAGTCACCT GAGTGGCTCC TCCTTGGGGA AGGCCAGCCG GGCCTCCAAG 1020

CCCCCCACCC TCATTGACGA AGAGGAAGAG GAGAAACTCT ATGAGGCGTG GAAGAAAGGG 1080

CGGGGCCTCC CCACAGGCAA GGTTCCCCAG GGCAGGGACA GCAGGGGAGA GGAGGAGGCC 1140

GAGGATGAGG ATGTGGAGCG AATCATCCGG GAATGGCAAA GCCGAAATGA GAGGTACCAG 1200

GCAGAAGGGC ACCGGAGGTG GGACAGGGAG GAGGAGGCAG AGGAGGAGGA GAGTGACACC 1260

GGCTCCTTCG TGAGGAGAAG ACGGAAGCAC ACGCTGAGTG AGAGCAGCAC CTCGGAGAGT 1320

GTTAGCAGCC GGGACATCCG AGTCCTGAAG CAGCAGCTGG AAATGAGCAG CCAGAACCGA 1380

GGTGGGAGAC ACCGCTCTGA CTCTGTGTCC ACGGAGAGCA CCTGGGACAT GTGGAACCAG 1440

AGGCTTCTGG AGATTGAGAA GGAAGCTTCA CGGAGGTACC ACTCCAGGAG CAAGAGAGAG 1500

GAGGTGGACT CCAGCTCCGA GGTGGGGAGT GGGATGCGGG AGGATGATGA GCAGAGTGTG 1560

TCCTCTGAGG CCAGCTCCTT CTATAACTTC TGCAGCAGGA ACAAGGACAA ACTCACTGCC 1620

CTGGAAAGGT GGAAGATCAA GAGAATTCAG TTTGGATTTC ACAAGAAAGA CTCAGAGGCA 1680

GGAGACGGCA GCAGTGAACA GGATGCAGAG GAGGTCGAGG GGGAGAAGAA GAACCCCTCT 1740

GACGTCAATC TGTCAGCCTA CCAGGCCTGG AAGCTGAAAC ACCAGAAGAA GGTGGGCAGT 1800

GAGAATAAGG AGGAGGTGGT GGAGCTCAGC AAGGGAGAGG ACTCGGCCTT GGCCAAGAAG 1860

AGGCAACGGA GGCTGGAGCT GCTGGAGAGG AGCAGGCAGA CGCTGCAGGA GAGCCAGTCC 1920

ATGGGAAGCT GGGAGGCGGA CAGCTCAGCT GCCAGCGGGA GCATCCCTCT GTCTGCATTC 1980

TGGTCAGCGG CCCCCTCAGT CAGTGCTGAT GGGGACACAG CATCCGTGCT TAGCACACAG 2040

AGCCACAGCT CCCACCCATC TCAGGCCCTA AGAAACGTAG GGGGATGCTT GGCCTCTGCC 2100

CCCACCACAC CTCTACCTAA CTTGCCAGTG GGGCCTGGAG ACACTATTTC CATCGCCAGC 2160

ATCCAAAACT GGATTGCCAA TGTAGTCAGT GAAACGCTGG CCCAGAAACA AAATGAAATA 2220

CTGCTCTTGT CCCGCTCACC ATCTGTTGCA AGCATGAAGG TGGCACCAGC CGCCAGCTGT 2280

CTGGGGGATG ACCAAGTCTC CATGCTTAGT GGACAGAGCA GCTCCTCCCT GGGTGGATCC 2340

CTGCTGCCTC AAAGTCAGGC AAGACCCAGC TCTGACACAC AGTCTGTTCT GTCCTCCCAT 2400

ACCACACAGA GCTCGAGGGC CGAAGGTACT GGGAGCAAAG TGAGGGGGAC CAGCAAGCCT 2460

ATCTATAGCC TCTTTGCTGA CAATGTCGAC CTAAGGGAGC TTGGCCGGAA GGAGAAAGAG 2520

ATGCAAATGG AGCTCAAGGA GAAGATGTCT GAGTACAAAA TGGAGAAGCT GGCCTCCGAC 2580

AACAAACGCA GCTCCCTTTT CAAGAAGAAG AAGGGCAGGG GAGATGAAGA TGATGACGTG 2640

GGTGACTGGG ATGAGGACAC TGACAGTGCC ATAGGGAGCT TCCGCTATTC TTCCCGCAGT 2700

AATTCTCAGA AACCCGAAAC AGACACCGCC TCCTCCCTGG CTGTTTCTGA TAGCTATGGA 2760

AGTGGCAGCA GAGCTGGCAA AGAGATGGAT AGCAGTATTA ATAAGTGGCT CAGTGGCCTC 2820

AGGACAGAGG AAAAATCTCC TCCCCAAAGT GATTGGTCTG GAAGCTCCAG GGGGAAGTGC 2880

ACCAGATCTT CCCTGCTCCG GGAGACAGAG TCTAAGTCCT CCAGTTATAA GTTCTCCAAA 2940

TCCCAGTCAG AGGAACAGGA CACCTCCTCC TACCACGAGG CCAATGGCAA CTCTGTAAGA 3000

AGCACTTCGA AGTTCTCTGC TTCCTCCACC AGGGAGGGCA GAGAGATGCA CACGTTCTCC 3060

AGGTCGACAT TCAGTGAGAC CTCAAGTTCT CGAGAGGAAA GCCCAGAGCC CTACTTCTTC 3120

CGTCGGACCC CTGAGCCCTC TGAAGGGGAA GAGTCCCCAG AACCACGGCG TCCGAATTGG 3180

GCCAGACCCA GGGACTGGGA AGATGTGGAA GAGTCATCCA AGTCGGACTT TTCTGAATTT 3240

GGAGCCAAGA GGAAATTCAC CCAGAGCTTC ATGAGGTCTG AAGAGGAGGG GGAGAAAGAG 3300

AGGATGGAAA AGAGAGAAGA GGGGAGGTTT GCTTCAGGAA GGCGGTCCCA GTATCGGAGA 3360

AGCACTGACA GGGAGGAGGA GGAGGAAATG GACGATGAAG CCATCATTGC TGCCTGGAGA 3420

CGCCGGCAAG AAGAAACCAG GACTAAGCTG CAGAGGAGGA GGGAAGATTA A 3471

Domain Profile

S: 1     evteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipv  60

         ev+e++p+++++++ +a+++  L++lgit+++na++++    ++Pe+++  +i+y++++v

Q: 136   EVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGV-YTGPEFYTGLEIQYLGVEV  194

         69**********************************8765.79*****************

S: 61    dDsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdA  119

         dD ++ +++q+f++aaef+dea  + +gkvlv +++G+sRSa+lv+aYLm+++++++ +A

Q: 195   DDFPEVNISQHFRKAAEFLDEAlLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAILEA  254

         **********************8999**********************************

S: 120   ieavkrkrpsiepnegfleQLlelekkl  147

         +++v++kr  i+pn+gfl+QL+el++kl

Q: 255   LMTVRKKR-PIYPNDGFLKQLRELNEKL  281

         ********.69*************9987

Domain Sequence
(FASTA)

EVDEVWPNVF IAEKSVAVNK GRLKRLGITH ILNAAHGTGV YTGPEFYTGL EIQYLGVEVD 60

DFPEVNISQH FRKAAEFLDE ALLTYRGKVL VSSEMGISRS AVLVVAYLMI FHNMAILEAL 120

MTVRKKRPIY PNDGFLKQLR ELNEKL 146

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR020417	; Atypical_DUSP.
IPR020405	; Atypical_DUSP_famA.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

PR01908	; ADSPHPHTASE.
PR01909	; ADSPHPHTASEA.

Created Date

20-Feb-2013