EKS-SUS-00269

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00269

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/Alpha	279.1	3.1E-83	118	315	198

Status

Unreviewed

Ensembl Protein

ENSSSCP00000008368

UniProt Accession

F1RPE8;

Protein Name

Protein Synonyms/Alias

Gene Name

EEF2K

Gene Synonyms/Alias

EEF2K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000007839	ENSSSCP00000008368	ENSSSCT00000008589

Organism

Sus scrofa

Functional Description

Protein Length

722

Protein Sequence
(FASTA)

MADEDLIFRL EGVGGDPTSR AGDSDADSDE EEGYFICPIT DDPGTHQNVS SKVHNYYSNL 60

TKSERYGSSG SPASSFHFKE AWKHAIEKAK HMPDPWAEFH LEDIATECAT RHRYNAVTGE 120

WLEDEVLIKM ASQPFGRGAM RECFRTKKLS NFLHTQHWKG ASNYVAKRYI ESVDRDVYFE 180

DVRLQMEAKL WGEEYNRHKP PKQVDIMQMC VIELKERPGR PLFHLEHYIE GKYIKYNSNS 240

GFVRDDNVRL TPQAFSHFTF ERSGHQLIVV DIQGVGDLYT DPQIHTERGT DFGDGNLGVR 300

GMALFFHSHA CNRICKSMGL APFDLSPRER DAVNQNTKLL QSAKTILRGT EEKCGSPRVR 360

TLSGSRPPLL LRLSENSGDE NMSDVTFDSL PSSPSSATPH SQKLDHLHWP VFSDLDNVAP 420

RDPDHLDNHR DSENSGDSGY PSEKRGELDD PYPQEHGHSN GNRKYESDED SLGSVGRVCV 480

EKWNLFNASR LHLPRPSAVA LEVQRLNALD FEKKIGKSIL GKVHLAMVRY HEGGRFCEKD 540

KEWDRESAVF HLEHAANLGE LEAIVGLGLM YSQLPHHILA DVSLEETEEN KTKGFDYLLK 600

AAEAGDRQSM ILVARAFDTG QNLSPDRSPN WPEALHWYNT ALETTDCDEG GEYDGMQDEP 660

RYTLLAREAE MLFTGGYGLD KDPQRSGDLY TQAAEAAMEA MKGRLANQYY EKAEEAWAQM 720

EE 722

Nucleotide Sequence
(FASTA)

ATGGCAGACG AAGACCTCAT CTTCCGCCTG GAAGGCGTGG GTGGCGACCC GACCTCCCGG 60

GCTGGGGATT CAGACGCCGA CAGTGACGAG GAAGAGGGTT ACTTCATCTG CCCCATCACC 120

GACGACCCCG GGACACACCA GAATGTCAGT TCCAAGGTTC ATAACTACTA CAGCAACCTA 180

ACAAAAAGTG AGCGCTACGG CTCCAGCGGG TCCCCGGCGA GCTCCTTCCA CTTCAAGGAA 240

GCCTGGAAGC ATGCCATCGA GAAGGCCAAG CACATGCCTG ACCCCTGGGC CGAGTTCCAC 300

CTGGAGGACA TTGCCACAGA ATGTGCCACG CGTCACAGGT ACAACGCCGT CACAGGGGAG 360

TGGCTGGAGG ATGAAGTCCT GATCAAGATG GCATCTCAGC CCTTCGGCCG GGGAGCAATG 420

AGGGAGTGCT TCAGAACGAA GAAGCTCTCC AACTTCCTGC ACACCCAGCA CTGGAAGGGG 480

GCTTCCAACT ACGTGGCAAA GCGCTACATC GAGTCCGTGG ACAGGGACGT GTACTTTGAG 540

GATGTGCGTC TACAGATGGA GGCCAAGCTC TGGGGAGAGG AGTATAATCG CCACAAGCCT 600

CCCAAGCAGG TGGACATCAT GCAGATGTGT GTCATAGAGC TGAAGGAGAG ACCAGGCCGG 660

CCCCTCTTCC ACCTGGAGCA TTATATTGAG GGCAAATACA TCAAATACAA CTCCAACTCG 720

GGCTTCGTCC GTGATGACAA CGTGCGCCTG ACGCCGCAGG CCTTCAGCCA CTTCACCTTT 780

GAGCGTTCCG GCCACCAGCT GATTGTGGTG GACATCCAGG GTGTGGGCGA CCTCTACACC 840

GACCCGCAGA TCCACACCGA GAGGGGCACT GACTTTGGAG ATGGCAACCT AGGTGTCCGT 900

GGGATGGCTC TCTTCTTCCA CTCTCATGCC TGCAACCGGA TTTGCAAGAG TATGGGCCTC 960

GCTCCCTTTG ACCTCTCCCC GAGAGAGAGG GACGCAGTGA ATCAGAACAC CAAGCTCCTG 1020

CAATCAGCCA AGACCATCTT GAGGGGGACA GAGGAGAAGT GTGGGAGCCC CCGGGTGAGG 1080

ACCCTCTCTG GGAGCCGGCC CCCCCTGCTC CTTCGCCTCT CAGAGAATTC TGGCGACGAG 1140

AACATGAGTG ATGTGACCTT CGACTCTCTC CCTTCCTCGC CATCTTCAGC CACGCCGCAC 1200

AGCCAGAAAC TGGACCACCT CCATTGGCCT GTGTTCAGCG ACCTGGATAA CGTGGCACCT 1260

CGAGACCCTG ACCATCTGGA CAACCACCGG GACTCTGAGA ACAGTGGGGA CAGCGGATAC 1320

CCCAGTGAGA AGCGGGGTGA ACTGGATGAT CCATATCCCC AGGAACATGG CCACTCGAAT 1380

GGTAACCGGA AGTACGAGTC GGATGAAGAC AGCCTGGGCA GCGTCGGACG GGTCTGCGTG 1440

GAGAAGTGGA ACCTCTTCAA CGCCTCCCGC CTCCACCTGC CCAGGCCTTC GGCTGTGGCC 1500

CTCGAAGTGC AGAGGCTCAA CGCTCTGGAC TTTGAGAAGA AAATCGGGAA GTCCATTTTG 1560

GGAAAGGTCC ACCTGGCCAT GGTGCGCTAC CACGAGGGCG GGCGCTTCTG CGAGAAGGAC 1620

AAGGAGTGGG ACCGGGAGTC GGCCGTCTTC CACCTGGAGC ATGCGGCCAA CCTGGGCGAG 1680

CTGGAGGCCA TCGTGGGCCT GGGACTCATG TACTCACAGC TGCCTCACCA CATCCTGGCC 1740

GACGTCTCTC TGGAGGAGAC AGAAGAGAAT AAAACCAAAG GATTTGATTA CTTACTGAAG 1800

GCAGCGGAAG CTGGCGACAG ACAGTCCATG ATTCTGGTGG CCCGAGCTTT TGACACCGGC 1860

CAGAACCTCA GCCCAGACAG GTCCCCAAAC TGGCCAGAGG CTCTGCACTG GTACAACACT 1920

GCCCTGGAGA CAACAGACTG TGATGAGGGC GGCGAGTATG ATGGGATGCA AGATGAGCCC 1980

CGGTACACGC TACTGGCCAG GGAGGCGGAG ATGCTGTTCA CAGGCGGCTA CGGGCTGGAC 2040

AAGGACCCAC AGAGATCAGG TGACTTGTAT ACTCAGGCAG CGGAGGCAGC AATGGAAGCC 2100

ATGAAAGGCC GGCTGGCCAA CCAGTACTAT GAGAAGGCTG AGGAGGCCTG GGCCCAGATG 2160

GAGGAATAA 2169

Domain Profile

S: 2     sesWsqqetivlikvlskeekkGalRkalrvkkgslflvkeelkevvryvakiykeqkvl  61

         +++W+++e  vlik++s+++++Ga+R+++r+kk+s+fl+ +++k++++yvak+y+e++++

Q: 118   TGEWLEDE--VLIKMASQPFGRGAMRECFRTKKLSNFLHTQHWKGASNYVAKRYIESVDR  175

         789*****..**************************************************

S: 62    hlylrdverqraaqklvtefnqvkPkkivyiprlievfLkdrtsknqlltvEeyllGefv  121

         ++y++dv+ q++a+ +++e+n++kP+k+v+i++++ ++Lk+r+++ +l+++E+y++G+++

Q: 176   DVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCVIELKERPGR-PLFHLEHYIEGKYI  234

         *********************************************.**************

S: 122   KynnnngdeikrenkleelmlafsHftyeytngellVvDlqGvgeklTDpqiatksrgtk  181

         Kyn+n+g  ++r+++++ +++afsHft+e+++++l+VvD+qGvg+ +TDpqi+t +rgt+

Q: 235   KYNSNSG--FVRDDNVRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHT-ERGTD  291

         *******..*********************************************.*****

S: 182   fgkanlgeraiknFfakhhCNeiC  205

         fg++nlg+r+++ Ff +h+CN+iC

Q: 292   FGDGNLGVRGMALFFHSHACNRIC  315

         ************************

Domain Sequence
(FASTA)

TGEWLEDEVL IKMASQPFGR GAMRECFRTK KLSNFLHTQH WKGASNYVAK RYIESVDRDV 60

YFEDVRLQME AKLWGEEYNR HKPPKQVDIM QMCVIELKER PGRPLFHLEH YIEGKYIKYN 120

SNSGFVRDDN VRLTPQAFSH FTFERSGHQL IVVDIQGVGD LYTDPQIHTE RGTDFGDGNL 180

GVRGMALFFH SHACNRIC 198

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0005509	; F:calcium ion binding
GO:0004686	; F:elongation factor-2 kinase activity
GO:0046777	; P:protein autophosphorylation
GO:0031952	; P:regulation of protein autophosphorylation

KEGG

ssc:100523723

;

InterPros

IPR017400	; Elongation_factor_2_kinase.
IPR011009	; Kinase-like_dom.
IPR004166	; MHCK_EF2_kinase.
IPR006597	; Sel1-like.
IPR011990	; TPR-like_helical.

Pfam

PF02816	; Alpha_kinase; 1.
PF08238	; Sel1; 4.

SMARTs

SM00811

; Alpha_kinase; 1.

Prosites

PS51158

; ALPHA_KINASE; 1.

Prints

Created Date

20-Feb-2013