EKS-SUS-00180

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00180

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	516.9	1.3E-155	4	287	284

Status

Unreviewed

Ensembl Protein

ENSSSCP00000009572

UniProt Accession

F1RYV0;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL2

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000008970	ENSSSCP00000009572	ENSSSCT00000009825

Organism

Sus scrofa

Functional Description

Protein Length

572

Protein Sequence
(FASTA)

MEKYENLGLV GEGSYGMVMK CRNKDTGRIV AIKKFLESDD DKMVKKIAMR EIKLLKQLRH 60

ENLVNLLEVC KKKKRWYLVF EFVDHTVLDD LELFPNGLDY QLVQKYLFQI INGIGFCHSH 120

NIIHRDIKPE NILVSQSGVV KLCDFGFART LAAPGEVYTD YVATRWYRAP ELLVGDVKYG 180

KAVDVWAIGC LVTEMLMGEP LFPGDSDIDQ LYHITLCLGN LIPRHQELFY KNPVFAGVRL 240

PEIKETVPLE RRYPKLSEVV IDLAKKCLHI DPDKRPFCAE LLHHDFFHVD GFAERFSQEL 300

QLKVQKDARN ISLSKKFQNR KKEKEKDDSL SEERKTLVVQ DTNADPKVKD SKVIKIKGSK 360

MDGEKVEKIS RALNASCLHD NGASHIKTVP STSLRDYSNG SVDHTRNPVM AIPPLVHGFS 420

AVAPAVNSGM GTIPGVQSYR YELGKSGQRY CLRTYLPMNR LNKSGHFNID AIIKVASEKS 480

LLQANKKRRE FSKTDVRLPE LNYNHLPELK ALEGIARNSR LIRKENKNLL ESRIPSLATI 540

DWHTPGIALH QVLGSPLSND SEADLPRVEH QH 572

Nucleotide Sequence
(FASTA)

ATGGAGAAAT ATGAGAACCT AGGACTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 60

TGCAGGAATA AAGATACTGG ACGAATTGTG GCTATCAAGA AGTTCTTAGA AAGTGATGAT 120

GACAAAATGG TTAAAAAAAT CGCTATGCGG GAAATCAAGT TACTAAAGCA ACTGAGGCAT 180

GAAAATCTGG TGAATCTGCT GGAAGTGTGT AAGAAAAAAA AGCGATGGTA CCTAGTCTTT 240

GAATTTGTTG ACCACACAGT TCTTGATGAT TTGGAGCTCT TTCCCAATGG ACTCGACTAC 300

CAGCTAGTTC AGAAGTATTT GTTTCAGATT ATCAATGGAA TTGGATTTTG TCACAGTCAC 360

AATATCATCC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGTGTCGTC 420

AAGTTATGTG ATTTTGGATT TGCACGGACA CTGGCAGCTC CTGGGGAGGT TTATACTGAC 480

TACGTGGCAA CACGATGGTA TAGAGCTCCT GAACTGTTGG TTGGGGACGT CAAGTACGGC 540

AAGGCTGTTG ATGTGTGGGC CATCGGCTGT CTGGTAACTG AAATGCTCAT GGGCGAACCC 600

CTTTTTCCCG GAGATTCTGA CATTGATCAG CTCTATCATA TTACGTTGTG CTTAGGTAAT 660

CTCATTCCAA GACATCAGGA GCTCTTTTAT AAAAATCCTG TGTTTGCTGG AGTCAGGTTG 720

CCTGAAATCA AAGAGACAGT ACCTCTCGAA AGACGCTATC CCAAGCTCTC CGAAGTTGTG 780

ATCGATTTAG CAAAGAAATG CTTACATATT GACCCAGACA AAAGGCCCTT CTGTGCTGAG 840

CTCTTACACC ATGATTTCTT TCATGTGGAT GGATTTGCTG AGAGGTTTTC TCAGGAACTG 900

CAGTTAAAAG TACAGAAAGA TGCCAGAAAC ATTTCTTTAT CTAAAAAATT CCAGAATAGA 960

AAGAAGGAAA AGGAAAAAGA TGATTCTTTA AGTGAAGAAA GAAAAACACT TGTGGTACAG 1020

GATACCAATG CTGATCCCAA AGTTAAGGAT TCTAAAGTAA TTAAAATAAA AGGGTCAAAA 1080

ATGGATGGAG AAAAAGTTGA AAAAATCAGT CGAGCTCTGA ATGCCAGCTG TCTCCATGAC 1140

AACGGGGCGA GCCACATCAA AACAGTGCCT TCAACAAGCC TCCGAGATTA CAGCAATGGC 1200

AGCGTGGACC ACACAAGAAA TCCAGTCATG GCGATTCCCC CACTGGTACA CGGTTTCTCT 1260

GCAGTGGCCC CTGCTGTGAA TTCTGGAATG GGGACTATCC CAGGAGTTCA GAGTTACAGG 1320

TATGAATTAG GAAAATCAGG GCAAAGATAT TGTTTAAGGA CATATTTGCC AATGAATAGG 1380

CTTAATAAGT CCGGACATTT CAATATAGAT GCTATTATTA AAGTTGCTAG TGAAAAGAGC 1440

CTACTTCAGG CGAATAAGAA AAGAAGGGAA TTCTCGAAGA CAGATGTCCG TTTGCCTGAA 1500

CTAAACTACA ATCATCTTCC TGAACTAAAA GCCTTGGAAG GCATTGCTCG AAATTCCAGG 1560

TTGATAAGAA AAGAGAACAA AAATCTTTTA GAATCTCGAA TTCCTTCTCT GGCCACTATT 1620

GACTGGCACA CTCCGGGTAT CGCATTACAT CAGGTATTGG GATCTCCCCT GTCAAACGAT 1680

TCAGAGGCTG ATTTACCTCG GGTGGAACAC CAGCACTGA 1719

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lg vGeGsyG+v+kcrnkdtg+ivaikkfles+ddk+vkkia+reikllkql+henl

Q: 4     YENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllev+++kk++ylvfe+vd+tvld+le +pnG++++lv+k+l+qi+++i fch++nii

Q: 64    VNLLEVCKKKKRWYLVFEFVDHTVLDDLELFPNGLDYQLVQKYLFQIINGIGFCHSHNII  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sgvvklcdfGfar+laapg+vytdyvatrwyrapellvgd+kyGk+v

Q: 124   HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGcl++e+l+Geplfpg+sd+dqly+i+ +lG+liprhq++f+kn+vfaGv+lpe+

Q: 184   DVWAIGCLVTEMLMGEPLFPGDSDIDQLYHITLCLGNLIPRHQELFYKNPVFAGVRLPEI  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++ +le++ypkl+ev++dl+kkcl++dp++r +c+ell+h++f

Q: 244   KETVPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFF  287

         ******************************************98

Domain Sequence
(FASTA)

YENLGLVGEG SYGMVMKCRN KDTGRIVAIK KFLESDDDKM VKKIAMREIK LLKQLRHENL 60

VNLLEVCKKK KRWYLVFEFV DHTVLDDLEL FPNGLDYQLV QKYLFQIING IGFCHSHNII 120

HRDIKPENIL VSQSGVVKLC DFGFARTLAA PGEVYTDYVA TRWYRAPELL VGDVKYGKAV 180

DVWAIGCLVT EMLMGEPLFP GDSDIDQLYH ITLCLGNLIP RHQELFYKNP VFAGVRLPEI 240

KETVPLERRY PKLSEVVIDL AKKCLHIDPD KRPFCAELLH HDFF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013