EKS-SUS-00063

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00063

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	334.7	5.4E-100	4	288	285

Status

Unreviewed

Ensembl Protein

ENSSSCP00000010226

UniProt Accession

D3K5N0;

Protein Name

Protein Synonyms/Alias

Cyclin-dependent kinase 20;

Gene Name

CDK20

Gene Synonyms/Alias

CDK20;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000009578	ENSSSCP00000010226	ENSSSCT00000010499

Organism

Sus scrofa

Functional Description

Protein Length

346

Protein Sequence
(FASTA)

MEQYCILGRI GEGAHGIVFK AKHVETGEIV ALKKVALRRL EDGIPNQALR EIKALQEIED 60

SQYVVQLKAV FPHGAGFVLA FEYMLSDLAE VLRHAQRPLA QAQVKSYLQM LLKGVAFCHA 120

NNIVHRDLKP ANLLISASGQ LKIADFGLAR VFSPDGSRLY THQVATRWYR APELLYGARQ 180

YNQGVDLWAV GCILGELLNG SPLFPGENDI EQLCCVLRIL GTPSPQVWPE ITELPDYNKI 240

SFKEQAPVPL EEVLPDASPQ ALDLLGRFLL YPPLQRIAAS QALLHQYFFT APLPAHPSEL 300

PIPHRPGGPT PKAHPGPPHV HDFHVDQPLE ESLLNPELIR PFILEG 346

Nucleotide Sequence
(FASTA)

ATGGAGCAGT ACTGCATCTT GGGCCGCATA GGGGAGGGCG CTCATGGCAT CGTCTTCAAG 60

GCCAAGCACG TGGAGACTGG AGAGATCGTG GCCCTCAAGA AGGTGGCCCT ACGGCGGCTG 120

GAGGATGGCA TCCCCAACCA GGCCCTGCGG GAGATCAAGG CCCTGCAGGA GATTGAGGAC 180

AGTCAGTATG TTGTGCAATT GAAGGCTGTG TTCCCGCACG GTGCAGGCTT TGTGCTGGCC 240

TTTGAGTACA TGCTGTCAGA TCTGGCTGAG GTGCTGCGCC ACGCCCAGAG GCCGCTGGCC 300

CAGGCACAGG TCAAGAGCTA TTTGCAGATG CTGCTCAAAG GCGTTGCCTT CTGCCATGCC 360

AACAACATTG TGCATCGGGA CCTGAAACCA GCCAACTTGC TAATCAGCGC CTCGGGCCAG 420

CTCAAGATAG CGGACTTTGG CCTGGCCCGG GTCTTTTCCC CAGATGGCAG CCGCCTCTAC 480

ACGCACCAGG TGGCCACCAG GTGGTACCGA GCCCCTGAGC TCCTGTATGG TGCCCGCCAG 540

TACAACCAGG GTGTTGACCT GTGGGCCGTG GGATGCATCC TGGGGGAGCT GTTGAACGGG 600

TCCCCCCTTT TCCCAGGGGA GAATGACATC GAACAGCTTT GCTGTGTGCT TCGCATCTTG 660

GGCACCCCCA GCCCTCAAGT CTGGCCGGAG ATCACAGAGC TGCCTGACTA CAACAAGATC 720

TCCTTCAAGG AGCAGGCACC CGTGCCCTTG GAGGAGGTGC TGCCCGATGC CTCTCCCCAG 780

GCCTTGGACC TGCTGGGGCG GTTCCTCCTC TACCCTCCAC TCCAGCGCAT TGCAGCCTCC 840

CAGGCCCTCC TGCACCAGTA CTTCTTCACA GCTCCCCTGC CGGCCCACCC CTCGGAGCTG 900

CCGATTCCCC ACCGCCCAGG GGGACCTACC CCCAAGGCCC ACCCAGGACC CCCCCACGTC 960

CATGACTTCC ACGTGGACCA GCCTCTGGAG GAGTCGCTGT TGAACCCGGA GCTGATTCGG 1020

CCCTTCATCC TGGAGGGCTG A 1041

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkel.khkn  59

         y  l +igeG++g v+kak+ etge+vAlKk++l + ++g+p +alrEi+ l+e+ + ++

Q: 4     YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIeDSQY  63

         677899*************************************************77899

S: 60    ivkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         +v+L+ v+  + + ++L fe++ +dL+++l++ ++  l +++vks+l++ll+g+a++H+n

Q: 64    VVQLKAVFP-HGAGFVLAFEYMLSDLAEVLRHAQR-PLAQAQVKSYLQMLLKGVAFCHAN  121

         *********.99********************999.************************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplkt.ytkevvTlwYraPelLlgakeY  178

         +i+HRDlKp+NlLis++g+lk+aDfGlar fs + ++ yt++v T+wYraPelL+ga++Y

Q: 122   NIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRlYTHQVATRWYRAPELLYGARQY  181

         *******************************8766544**********************

S: 179   stavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ks  237

         ++ vD+W+vgcil ell+ +plf+g+++i+ql  ++++lgtps +vwpe+++lp+y+  s

Q: 182   NQGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRILGTPSPQVWPEITELPDYNkIS  241

         *********************************************************88*

S: 238   fpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         f+++++  l+e++++++ +aldll ++l + p +Ri a++al h+yf

Q: 242   FKEQAPVPLEEVLPDASPQALDLLGRFLLYPPLQRIAASQALLHQYF  288

         **********************************************9

Domain Sequence
(FASTA)

YCILGRIGEG AHGIVFKAKH VETGEIVALK KVALRRLEDG IPNQALREIK ALQEIEDSQY 60

VVQLKAVFPH GAGFVLAFEY MLSDLAEVLR HAQRPLAQAQ VKSYLQMLLK GVAFCHANNI 120

VHRDLKPANL LISASGQLKI ADFGLARVFS PDGSRLYTHQ VATRWYRAPE LLYGARQYNQ 180

GVDLWAVGCI LGELLNGSPL FPGENDIEQL CCVLRILGTP SPQVWPEITE LPDYNKISFK 240

EQAPVPLEEV LPDASPQALD LLGRFLLYPP LQRIAASQAL LHQYF 285

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

ssc:100157041

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013