EPS-SUS-00127

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-SUS-00127

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP1	386.4	3.1E-116	58	249	192

Status

Unreviewed

Ensembl Protein

ENSSSCP00000010492

UniProt Accession

F1RNL4;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

PPP1CC

Gene Synonyms/Alias

PPP1CC;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000009828	ENSSSCP00000010492	ENSSSCT00000010772

Organism

Sus scrofa

Functional Description

Protein Length

321

Protein Sequence
(FASTA)

MADIDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP ILLELEAPLK 60

ICGDIHGQYY DLLRLFIRGF PARKQYLFLG DYVDRGKQSL ETICLLLAYI KYPENFFLLR 120

GNHECASINR IYGFYDECKR RYNIKLWKTF TDCFNCLPIA AIVDEKIFCC HGGLSPDLQS 180

MEQIRRIMRP TDVPDQGLLC DLLWSDPDKD VLGWGENDRG VSFTFGAEVV AKFLHKHDLD 240

LICRAHQVVE DGYEFFAKRQ LVTLFSAPNY CGEFDNAGAM MSVDETLMCS FQILKPAEKK 300

KPNATRPVTP PRGMITKQAK K 321

Nucleotide Sequence
(FASTA)

ATGGCGGATA TAGATAAACT CAACATCGAC AGCATCATCC AACGGCTGCT GGAAGTGAGA 60

GGGTCCAAAC CTGGTAAGAA TGTCCAGCTA CAAGAGAATG AAATCAGAGG ACTGTGCTTA 120

AAGTCCCGAG AGATCTTTCT CAGTCAGCCT ATCCTACTCG AACTTGAAGC ACCACTCAAA 180

ATATGTGGTG ATATCCATGG GCAATACTAT GATTTGCTTC GACTTTTTAT ACGGGGGTTT 240

CCCGCCAGAA AGCAATACCT GTTTCTTGGG GACTATGTGG ACAGGGGGAA ACAGTCATTG 300

GAAACTATCT GCCTTTTATT GGCTTACATC AAATATCCCG AGAATTTTTT TCTTCTCAGA 360

GGAAACCACG AATGTGCCAG CATCAATAGA ATTTATGGAT TTTATGATGA ATGTAAAAGA 420

AGATATAACA TTAAACTATG GAAAACTTTC ACAGACTGCT TTAACTGTTT ACCGATAGCA 480

GCCATCGTGG ATGAGAAAAT ATTCTGCTGT CATGGAGGTT TATCACCAGA TCTTCAATCT 540

ATGGAGCAGA TTCGGCGAAT TATGCGACCA ACTGATGTAC CAGATCAAGG TCTTCTTTGT 600

GATCTTTTGT GGTCTGACCC CGATAAAGAT GTCTTAGGCT GGGGTGAAAA TGACAGAGGA 660

GTGTCCTTCA CATTTGGTGC AGAAGTGGTT GCAAAATTTC TCCATAAGCA TGATTTGGAT 720

CTTATATGTA GAGCCCATCA GGTGGTTGAA GATGGATATG AATTTTTTGC AAAGAGGCAG 780

TTGGTCACTC TGTTTTCTGC GCCCAATTAT TGTGGAGAGT TTGACAATGC AGGTGCCATG 840

ATGAGTGTGG ACGAAACACT AATGTGTTCT TTTCAGATTT TAAAGCCTGC AGAGAAAAAG 900

AAGCCGAATG CCACGAGACC TGTAACACCT CCAAGGGGTA TGATCACAAA GCAAGCAAAG 960

AAATAG 966

Domain Profile

S: 1     pvkicgdihgqykdllrlfeyggfppeanylflgdyvdrgkqsleticlllaykikypen  60

         p+kicgdihgqy+dllrlf   gfp +++ylflgdyvdrgkqsleticlllay ikypen

Q: 58    PLKICGDIHGQYYDLLRLFI-RGFPARKQYLFLGDYVDRGKQSLETICLLLAY-IKYPEN  115

         89*****************5.69*****************************9.9*****

S: 61    ffllrgnhesasinriygfydeckrrynvklwktftdcfnclpvaaiidekilcvhggls  120

         ffllrgnhe+asinriygfydeckrryn+klwktftdcfnclp+aai+deki+c+hggls

Q: 116   FFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLS  175

         ************************************************************

S: 121   pdlksleqirrikrptdvpdegllcdllwsdpdkdvkgwgendrgvsftfgadvvakflk  180

         pdl+s+eqirri+rptdvpd+gllcdllwsdpdkdv gwgendrgvsftfga+vvakfl+

Q: 176   PDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLH  235

         ************************************************************

S: 181   khdldlicrahqvv  194

         khdldlicrahqvv

Q: 236   KHDLDLICRAHQVV  249

         *************8

Domain Sequence
(FASTA)

PLKICGDIHG QYYDLLRLFI RGFPARKQYL FLGDYVDRGK QSLETICLLL AYIKYPENFF 60

LLRGNHECAS INRIYGFYDE CKRRYNIKLW KTFTDCFNCL PIAAIVDEKI FCCHGGLSPD 120

LQSMEQIRRI MRPTDVPDQG LLCDLLWSDP DKDVLGWGEN DRGVSFTFGA EVVAKFLHKH 180

DLDLICRAHQ VV 192

Keyword

Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005741	; C:mitochondrial outer membrane
GO:0070688	; C:MLL5-L complex
GO:0005730	; C:nucleolus
GO:0072357	; C:PTW/PP1 phosphatase complex
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation
GO:0046822	; P:regulation of nucleocytoplasmic transport

KEGG

InterPros

IPR004843	; Metallo_PEstase_dom.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF00149

; Metallophos; 1.

SMARTs

SM00156

; PP2Ac; 1.

Prosites

PS00125

; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013