EKS-SUS-00182

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00182

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	464.6	1.1E-139	13	297	285

Status

Unreviewed

Ensembl Protein

ENSSSCP00000030501

UniProt Accession

K7GL55;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL5

Gene Synonyms/Alias

CDKL5;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000012156	ENSSSCP00000012941	ENSSSCT00000013297
ENSSSCG00000012156	ENSSSCP00000028584	ENSSSCT00000033642
ENSSSCG00000012156	ENSSSCP00000030501	ENSSSCT00000032659

Organism

Sus scrofa

Functional Description

Protein Length

792

Protein Sequence
(FASTA)

MKIPNIGNVM NKFEILGVVG EGAYGVVLKC RHKETHEIVA IKKFKDSEEN EEVKETTLRE 60

LKMLRTLKQE NIVELKEAFR RRGKLYLVFE YVEKNMLELL EEMPNGVPPE KVKSYIYQLI 120

KAIHWCHKND IVHRDIKPEN LLISHNDVLK LCDFGFARNL SEGNNANYTE YVATRWYRSP 180

ELLLGAPYGK SVDMWSVGCI LGELSDGQPL FPGESEIDQL FTIQKVLGPL PSEQMKLFYS 240

NPRFHGLRFP AVNHPQSLER RYLGILNSVL LDLMKNLLKL DPADRYLTEQ CLNHPTFQTQ 300

RLLDRSPSRS AKRKPYHVES STLSNRNQAS KTAALQSHHR SNSKDIQNLG VGLPRADEGL 360

PANESFLNGN LAGATLSPMH TKTYQASSQP GSASKDLTNN NIPHLLSPKE AKSKTEFDFN 420

IDPKPSEGPG TKYLKSSSRS QQNRHSFMES SQSKAGTLQP SEKQSRHSYI DTIPQSSRSP 480

SYRTKAKSHG ALSDSKSVSN LSEARAQMAE SNTSRYFPSS CLDLNSPTSP TPTRHSDTRT 540

LLSPSGRNNR SEGTLDSRRT TTRHSKTMEE LKLPEHMDSS HSHSLSAPHE SFSYGLGYTS 600

PFSSQQRPHR HSMYVTRDKV RAKGLDGSLS VGQGMAARAN SLQLLSPQPG EQLPPEMTVA 660

RSSGKESSRE GTSSFHARQK SEGGAYHDPH SDDGNAPKEN RHLYNDPVPR RVGSFYRVPS 720

PRPDNSFHEN NVSTRVSSLP SESSSGTNHS KRQPAFDPWK SPENISHSEQ LKEKEKQGFF 780

RSMKKKKKKS QT 792

Nucleotide Sequence
(FASTA)

ATGAAGATTC CTAACATTGG TAATGTGATG AATAAATTTG AGATCCTTGG GGTTGTAGGT 60

GAAGGAGCCT ATGGAGTTGT ACTTAAATGC AGACACAAGG AAACACATGA AATTGTGGCA 120

ATCAAGAAGT TCAAGGACAG TGAAGAAAAT GAAGAAGTCA AGGAAACGAC TTTACGAGAG 180

CTTAAAATGC TTCGTACTCT CAAGCAGGAA AACATTGTGG AGTTGAAGGA AGCCTTTCGT 240

CGGAGGGGGA AATTGTACTT GGTGTTTGAG TATGTTGAAA AAAATATGCT TGAGTTGCTG 300

GAAGAAATGC CAAATGGAGT TCCACCTGAA AAAGTAAAAA GTTATATCTA TCAGTTAATC 360

AAAGCTATTC ACTGGTGCCA TAAGAATGAT ATTGTTCATC GAGATATAAA ACCAGAAAAT 420

CTCTTAATCA GCCACAATGA CGTTTTGAAA CTATGTGACT TTGGTTTTGC ACGGAATCTA 480

TCAGAAGGCA ATAATGCTAA TTACACAGAA TATGTGGCCA CCAGGTGGTA TCGGTCCCCA 540

GAACTCTTAC TTGGAGCTCC CTATGGAAAG TCTGTAGATA TGTGGTCAGT GGGCTGTATT 600

CTTGGGGAGC TTAGTGATGG ACAGCCTTTA TTTCCTGGAG AGAGTGAAAT TGACCAACTT 660

TTTACTATTC AGAAGGTGCT AGGACCACTT CCATCTGAGC AGATGAAGCT CTTCTACAGC 720

AATCCTCGCT TCCACGGGCT CCGGTTTCCA GCTGTTAACC ATCCTCAGTC ATTGGAGAGA 780

AGATACCTTG GAATTTTAAA TAGTGTTTTA CTTGACTTAA TGAAGAATTT ACTGAAGTTG 840

GACCCAGCTG ACAGATACTT GACAGAACAG TGTTTGAATC ACCCTACATT CCAAACCCAG 900

AGACTTTTGG ATCGCTCCCC TTCAAGGTCA GCAAAAAGAA AACCTTACCA CGTGGAAAGC 960

AGCACTTTGT CTAATAGAAA CCAAGCCAGC AAAACTGCTG CCCTGCAGTC TCACCACAGA 1020

TCTAACAGCA AGGACATCCA GAACCTAGGT GTGGGTCTGC CCCGGGCTGA TGAAGGTCTT 1080

CCTGCCAACG AAAGCTTCTT AAACGGAAAC CTTGCTGGAG CTACTCTTAG TCCCATGCAC 1140

ACCAAAACCT ACCAAGCGAG CAGCCAGCCT GGGTCCGCCA GCAAAGATCT GACCAACAAC 1200

AACATACCAC ACCTTCTCAG CCCCAAAGAG GCCAAGTCAA AGACAGAATT TGATTTTAAT 1260

ATCGACCCAA AGCCTTCAGA AGGCCCGGGC ACGAAGTACC TTAAGTCAAG CAGCAGATCT 1320

CAGCAGAACC GGCACTCATT TATGGAAAGT TCGCAGAGCA AAGCCGGGAC GCTGCAGCCC 1380

AGTGAAAAGC AGAGTCGGCA TAGCTACATC GACACCATTC CCCAGTCCTC TAGGAGTCCC 1440

TCCTACAGGA CCAAGGCCAA AAGCCATGGG GCACTGAGTG ACTCCAAGTC CGTGAGCAAC 1500

CTGTCGGAAG CCAGGGCCCA GATGGCAGAG TCCAATACCA GTAGGTACTT CCCATCCAGC 1560

TGCTTGGACT TGAACTCTCC CACCAGCCCA ACCCCCACCA GGCACAGCGA CACGAGAACT 1620

TTGCTCAGTC CCTCGGGGAG AAATAACCGA AGTGAGGGCA CTCTTGACTC CCGCCGAACC 1680

ACAACCAGGC ATTCTAAGAC GATGGAGGAG CTGAAGCTGC CGGAGCACAT GGACAGCAGC 1740

CACTCCCATT CGCTGTCGGC ACCTCATGAA TCCTTCTCGT ATGGGCTGGG CTACACCAGC 1800

CCCTTCTCCT CCCAGCAGCG TCCACACAGG CACTCCATGT ATGTGACCCG GGACAAAGTG 1860

AGAGCCAAAG GCTTGGATGG AAGCCTGAGC GTAGGACAAG GGATGGCGGC CAGAGCTAAC 1920

AGCCTGCAGC TCTTATCACC TCAGCCTGGA GAGCAGCTCC CTCCAGAGAT GACTGTGGCG 1980

CGATCTTCTG GGAAGGAGTC CTCCAGAGAA GGCACCTCTT CCTTCCATGC GAGGCAGAAG 2040

TCTGAGGGTG GAGCATATCA TGACCCCCAT TCTGATGATG GCAATGCCCC CAAAGAAAAC 2100

AGACACCTGT ACAATGATCC TGTTCCGAGG AGAGTCGGCA GCTTCTACCG AGTGCCATCT 2160

CCACGTCCAG ACAATTCTTT CCATGAAAAT AACGTGTCAA CCAGAGTTTC TTCCCTACCA 2220

TCAGAAAGCA GTTCTGGAAC GAACCACTCA AAAAGACAAC CAGCATTCGA TCCATGGAAA 2280

AGTCCCGAAA ACATTAGTCA TTCTGAACAA CTCAAGGAAA AGGAAAAACA AGGTTTTTTC 2340

AGGTCAATGA AAAAGAAAAA GAAGAAATCT CAAACA 2376

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         +e lg+vGeG+yGvvlkcr+k+t++ivaikkf++se+++evk+++lre+k+l++lk+en+

Q: 13    FEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENI  72

         799*********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         v+l+e+frr+ klylvfeyv+k++l+ le++pnGv+ e+vk+++yq++kai++chkn+i+

Q: 73    VELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIV  132

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarlla.apgdvytdyvatrwyrapellvgdtkyGks  179

         hrdikpen+lis+++v+klcdfGfar+l+ +++++yt+yvatrwyr+pell+g + yGks

Q: 133   HRDIKPENLLISHNDVLKLCDFGFARNLSeGNNANYTEYVATRWYRSPELLLG-APYGKS  191

         ****************************98999********************.9*****

S: 180   vdvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpe  239

         vd+w++Gc+l el++G+plfpg+s++dql++i+k+lG+l ++++k+f++n++f+G+++p+

Q: 192   VDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPA  251

         ************************************************************

S: 240   vedleslekkyp.klnevlldllkkclkldpaerlsceellkheyf  284

         v++++sle++y   ln+vlldl+k++lkldpa+r+++e++l+h++f

Q: 252   VNHPQSLERRYLgILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTF  297

         ***********9899****************************998

Domain Sequence
(FASTA)

FEILGVVGEG AYGVVLKCRH KETHEIVAIK KFKDSEENEE VKETTLRELK MLRTLKQENI 60

VELKEAFRRR GKLYLVFEYV EKNMLELLEE MPNGVPPEKV KSYIYQLIKA IHWCHKNDIV 120

HRDIKPENLL ISHNDVLKLC DFGFARNLSE GNNANYTEYV ATRWYRSPEL LLGAPYGKSV 180

DMWSVGCILG ELSDGQPLFP GESEIDQLFT IQKVLGPLPS EQMKLFYSNP RFHGLRFPAV 240

NHPQSLERRY LGILNSVLLD LMKNLLKLDP ADRYLTEQCL NHPTF 285

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>