EPS-SUS-00125

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-SUS-00125

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP1	414.9	5.7E-125	58	251	194

Status

Unreviewed

Ensembl Protein

ENSSSCP00000013730

UniProt Accession

Q2EHH8; F1RUX8;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

LOC733611

Gene Synonyms/Alias

LOC733611;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000012913	ENSSSCP00000013730	ENSSSCT00000014116

Organism

Sus scrofa

Functional Description

Protein Length

330

Protein Sequence
(FASTA)

MSDSEKLNLD SIIGRLLEVQ GSRPGKNVQL TENEIRGLCL KSREIFLSQP ILLELEAPLK 60

ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL 120

LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL 180

QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KDVQGWGEND RGVSFTFGAE VVAKFLHKHD 240

LDLICRAHQV VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAD 300

KNKGKYGQFS GLNPGGRPIT PPRNSAKAKK 330

Nucleotide Sequence
(FASTA)

ATGTCCGACA GCGAGAAGCT CAACCTGGAC TCTATCATCG GGCGCCTGCT GGAAGTGCAG 60

GGCTCGCGGC CTGGAAAGAA TGTACAGCTG ACAGAGAACG AGATCCGTGG TCTGTGCCTC 120

AAATCCCGGG AGATTTTCCT GAGCCAGCCC ATCCTTCTGG AGCTGGAGGC ACCCCTCAAG 180

ATCTGCGGTG ACATCCACGG CCAGTACTAT GACCTTCTGC GGCTGTTCGA GTACGGCGGC 240

TTCCCTCCAG AGAGCAACTA CCTGTTCCTG GGGGACTACG TGGACCGGGG CAAGCAGTCT 300

TTGGAGACCA TCTGCCTGCT GCTGGCCTAT AAGATCAAGT ACCCGGAGAA CTTCTTCCTG 360

CTCCGTGGGA ACCACGAGTG TGCCAGCATC AACCGCATCT ATGGCTTCTA CGATGAGTGC 420

AAGAGACGCT ACAACATCAA GCTGTGGAAA ACCTTCACTG ACTGCTTCAA CTGCCTGCCT 480

ATCGCTGCCA TTGTGGACGA GAAGATCTTT TGCTGCCACG GAGGCCTGTC CCCCGACCTG 540

CAGTCCATGG AGCAGATTCG GCGTATCATG CGGCCCACAG ACGTGCCTGA CCAGGGCTTA 600

CTGTGTGACC TGCTGTGGTC TGACCCCGAC AAGGACGTGC AGGGCTGGGG CGAGAATGAC 660

CGCGGCGTCT CCTTTACCTT TGGAGCGGAG GTGGTGGCCA AGTTCCTGCA CAAGCACGAC 720

TTGGATCTCA TCTGCCGGGC ACACCAGGTG GTAGAAGATG GCTACGAGTT CTTTGCCAAG 780

AGGCAGCTGG TGACACTCTT CTCAGCTCCT AACTACTGCG GCGAGTTTGA CAACGCAGGC 840

GCCATGATGA GCGTGGACGA GACGCTCATG TGCTCCTTCC AGATCCTCAA GCCCGCCGAC 900

AAGAACAAGG GGAAATATGG GCAGTTCAGT GGCCTGAATC CTGGAGGCCG GCCCATCACC 960

CCACCCCGCA ACTCCGCCAA AGCCAAGAAA TAG 993

Domain Profile

S: 1     pvkicgdihgqykdllrlfeyggfppeanylflgdyvdrgkqsleticlllaykikypen  60

         p+kicgdihgqy+dllrlfeyggfppe+nylflgdyvdrgkqsleticlllaykikypen

Q: 58    PLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPEN  117

         89**********************************************************

S: 61    ffllrgnhesasinriygfydeckrrynvklwktftdcfnclpvaaiidekilcvhggls  120

         ffllrgnhe+asinriygfydeckrryn+klwktftdcfnclp+aai+deki+c+hggls

Q: 118   FFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLS  177

         ************************************************************

S: 121   pdlksleqirrikrptdvpdegllcdllwsdpdkdvkgwgendrgvsftfgadvvakflk  180

         pdl+s+eqirri+rptdvpd+gllcdllwsdpdkdv+gwgendrgvsftfga+vvakfl+

Q: 178   PDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLH  237

         ************************************************************

S: 181   khdldlicrahqvv  194

         khdldlicrahqvv

Q: 238   KHDLDLICRAHQVV  251

         *************8

Domain Sequence
(FASTA)

PLKICGDIHG QYYDLLRLFE YGGFPPESNY LFLGDYVDRG KQSLETICLL LAYKIKYPEN 60

FFLLRGNHEC ASINRIYGFY DECKRRYNIK LWKTFTDCFN CLPIAAIVDE KIFCCHGGLS 120

PDLQSMEQIR RIMRPTDVPD QGLLCDLLWS DPDKDVQGWG ENDRGVSFTF GAEVVAKFLH 180

KHDLDLICRA HQVV 194

Keyword

Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0070688	; C:MLL5-L complex
GO:0072357	; C:PTW/PP1 phosphatase complex
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0048754	; P:branching morphogenesis of a tube
GO:0030324	; P:lung development
GO:0006470	; P:protein dephosphorylation

KEGG

ssc:733611

;

InterPros

IPR004843	; Metallo_PEstase_dom.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF00149

; Metallophos; 1.

SMARTs

SM00156

; PP2Ac; 1.

Prosites

PS00125

; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013