EKS-SUS-00199

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00199

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	364.5	4.1E-109	136	396	261

Status

Unreviewed

Ensembl Protein

ENSSSCP00000014439

UniProt Accession

F1SA79;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K7

Gene Synonyms/Alias

MAP2K7;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000013588	ENSSSCP00000014439	ENSSSCT00000014840

Organism

Sus scrofa

Functional Description

Protein Length

536

Protein Sequence
(FASTA)

MAASSLEQKL SRLEAKLKQE NREARRRIDL NLDISPQRPR PIIVITLSPA PAPSQRAALQ 60

LPLANDGGSR SPSSESSPQH PTPPTRPRHM LGLPSTLFTP RSMESIEIDQ KLQEIMKQTG 120

YLTIGGQRYQ AEINDLENLG EMGSGTCGQV WKMRFRKTGH VIAVKQMRRS GNKEENKRIL 180

MDLDVVLKSH DCPYIVQCFG TFITNTDVFI AMELMGTCAE KLKKRMQGPI PERILGKMTV 240

AIVKALYYLK EKHGVIHRDV KPSNILLDER GQIKLCDFGI SGRLVDSKAK TRSAGCAAYM 300

APERIDPPDP TKPDYDIRAD VWSLGISLVE LATGQFPYKN CKTDFEVLTK VLQEEPPLLP 360

GHMGFSGDFQ SFVKDCLTKD HRKRPKYNKL LEHSFIRRYE ALEVDVASWF KDVMAKTESP 420

RTSGVLSQHH LPFFSAPVSR GTWALAAPTP LQSGAVGRGG RLPAPRWAAR GPGQQPRVCA 480

GRPGTSLPAL GPDPAPLLSD SVLTPGPGPR LGAAARGLPS RFLRHLPATA AVPGCR 536

Nucleotide Sequence
(FASTA)

ATGGCGGCGT CCTCCCTGGA GCAGAAGCTG TCCCGCCTGG AGGCAAAGCT GAAGCAGGAG 60

AACCGCGAGG CCCGGCGGAG GATTGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 120

CCCATTATTG TGATCACTCT AAGCCCTGCT CCTGCCCCGT CCCAACGAGC AGCCCTGCAG 180

CTCCCACTGG CCAACGATGG GGGCAGCCGC TCACCATCCT CTGAGAGCTC CCCGCAGCAC 240

CCCACGCCTC CCACCCGGCC CCGCCACATG CTGGGGCTCC CGTCAACCCT CTTCACACCC 300

CGCAGCATGG AGAGCATTGA GATTGACCAG AAGCTGCAGG AGATCATGAA GCAGACGGGC 360

TATCTGACCA TCGGGGGCCA GCGCTACCAG GCAGAAATCA ATGATCTGGA GAACCTGGGG 420

GAGATGGGCA GCGGCACCTG CGGCCAGGTG TGGAAAATGC GTTTCCGGAA GACCGGGCAT 480

GTCATTGCTG TCAAGCAAAT GCGGCGCTCG GGGAACAAGG AGGAGAACAA GCGGATCCTC 540

ATGGACCTGG ACGTGGTACT CAAGAGCCAC GACTGCCCCT ACATCGTGCA GTGCTTCGGG 600

ACCTTCATCA CCAATACGGA CGTCTTCATC GCCATGGAGC TCATGGGCAC GTGCGCTGAG 660

AAGCTCAAGA AGCGGATGCA GGGCCCCATC CCTGAGCGGA TCCTGGGCAA GATGACAGTG 720

GCGATTGTCA AGGCGCTTTA CTACCTGAAG GAGAAGCACG GTGTGATCCA TCGCGATGTC 780

AAGCCCTCCA ACATCCTGCT GGATGAGCGG GGCCAGATCA AGCTCTGCGA TTTCGGCATC 840

AGTGGCCGCC TCGTCGACTC CAAGGCCAAA ACGCGGAGCG CAGGCTGCGC AGCCTACATG 900

GCACCCGAGC GCATCGACCC CCCGGACCCT ACCAAGCCTG ACTACGACAT TCGGGCAGAC 960

GTGTGGAGCT TGGGCATCTC CTTGGTGGAG CTGGCGACAG GACAGTTTCC CTACAAGAAC 1020

TGCAAGACGG ATTTTGAGGT TCTTACTAAG GTTCTGCAGG AAGAACCCCC ACTCCTGCCC 1080

GGTCACATGG GCTTCTCGGG GGACTTTCAG TCCTTTGTCA AAGACTGCCT TACTAAAGAT 1140

CACAGGAAGA GACCAAAGTA TAATAAGCTA CTTGAACACA GTTTCATCAG GCGCTACGAG 1200

GCGCTGGAGG TGGACGTGGC ATCCTGGTTC AAGGATGTCA TGGCGAAGAC CGAGTCGCCT 1260

CGGACAAGCG GGGTCCTGAG CCAGCACCAC CTGCCCTTCT TCAGCGCCCC CGTTTCCCGC 1320

GGCACCTGGG CCCTGGCTGC GCCGACCCCT CTTCAGTCTG GAGCTGTCGG ACGCGGAGGA 1380

CGCCTTCCTG CGCCGCGCTG GGCCGCTCGA GGTCCCGGCC AACAGCCGCG TGTATGTGCA 1440

GGCCGCCCTG GCACGTCCCT CCCCGCGCTG GGGCCTGACC CTGCACCGCT GCTCAGTGAC 1500

TCCGTCCTCA CGCCCGGCCC CGGGCCCCGC CTTGGCGCTG CTGCGCGGGG GCTGCCCAGC 1560

CGATTCCTCC GTCACCTTCC CGCCACCGCG GCGGTTCCCG GGTGCCGC 1608

Domain Profile

S: 1     lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi  60

         le+l+e+G+G++g+V+k++++k+g+++avK++r++ +kee+k+il++l+v+ ks+++pyi

Q: 136   LENLGEMGSGTCGQVWKMRFRKTGHVIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYI  195

         7899********************************************************

S: 61    vkfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylke  120

         v+++G+f++++dv+i+melm  t+ +k+ k++   ++ ipe++lgk++va+vkal ylke

Q: 196   VQCFGTFITNTDVFIAMELMG-TCAEKLKKRM---QGPIPERILGKMTVAIVKALYYLKE  251

         *********************.*****99996...9************************

S: 121   klkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg....  175

         k+ +iHRDvKPsNiL++++G++KlCDFG+sg+lvds Ak++ +G+++YmaPEri++

Q: 252   KHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRsAGCAAYMAPERIDPpdpt  311

         *******************************************************99999

S: 176   kkkYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpee.efseefqe  234

         k++Y++++dvWslG++lvelatg++py+++k+++e+l+++++eepp lp +  fs +fq+

Q: 312   KPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHmGFSGDFQS  371

         9************************************************9999*******

S: 235   fvskClkkdekeRpklkellkhafi  259

         fv++Cl+kd+++Rpk+++ll+h+fi

Q: 372   FVKDCLTKDHRKRPKYNKLLEHSFI  396

         ***********************97

Domain Sequence
(FASTA)

LENLGEMGSG TCGQVWKMRF RKTGHVIAVK QMRRSGNKEE NKRILMDLDV VLKSHDCPYI 60

VQCFGTFITN TDVFIAMELM GTCAEKLKKR MQGPIPERIL GKMTVAIVKA LYYLKEKHGV 120

IHRDVKPSNI LLDERGQIKL CDFGISGRLV DSKAKTRSAG CAAYMAPERI DPPDPTKPDY 180

DIRADVWSLG ISLVELATGQ FPYKNCKTDF EVLTKVLQEE PPLLPGHMGF SGDFQSFVKD 240

CLTKDHRKRP KYNKLLEHSF I 261

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004708	; F:MAP kinase kinase activity
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007257	; P:activation of JUN kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013