EKS-SUS-00183

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00183

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	364.9	2.6E-109	4	293	290

Status

Unreviewed

Ensembl Protein

ENSSSCP00000015212

UniProt Accession

F1RHD0;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000014302	ENSSSCP00000015212	ENSSSCT00000015625

Organism

Sus scrofa

Functional Description

Protein Length

588

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKRKDTGQIV AIKIFYEKPE KSVNKIATRE IKFLKQFRHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTVLDEL QHYCHGLESR RLRKYLFQIL RAIDYLHTNN 120

IIHRDIKPEN ILVSQSGVTK LCDFGFARTL AAPGDIYTDY VATRWYRAPE LVLKDTSYGK 180

KPTEIWLKGY LSGILYSGHL FLIDMEKLIF MEKLVLVVGF TTFHLHEGKT SFKLKTLFVG 240

LFIKRLRAWK TSKHKYYVLP SFRGRIKIIK QACLQIDPDE RISTTDLLHH EYFTRDGFIE 300

KFIPELRAKL LQEAKVNSFI KPKGNSKENE LMKDERKTIY TNTLLSNSVW GKEVEKEKKP 360

KEIKVRVIKV RGGKGDVLEP KKTEHEGAHC QQDAVEIAHT VSQDANISDP LNPLNPSTNS 420

TGMKDDPHAG GSMVMPPINL TSSNLMASNP SSNPSHSHSR LSERAKKRRT SSQFVGQVMS 480

NSKHENTGPS QVSQMEKSAF NDRTGPSDQM ANGNKRKLNF SRFERKEFHF PELPFIIPSK 540

EMKGMEVKQI KVLKKESKKI NSSKIPTLLN ADQYQEKEEV KLFVYSFY 588

Nucleotide Sequence
(FASTA)

ATGGAGATGT ATGAAACCCT TGGAAAAGTA GGAGAGGGAA GTTATGGAAC AGTCATGAAG 60

TGTAAACGTA AGGATACTGG GCAGATAGTG GCCATTAAGA TATTTTATGA GAAACCAGAG 120

AAATCTGTCA ACAAAATTGC AACGAGAGAA ATAAAGTTTC TAAAGCAATT TCGTCATGAA 180

AACCTGGTCA ATCTGATTGA AGTTTTTAGA CAGAAAAAGA AAATTCATTT GGTGTTTGAA 240

TTTATTGACC ACACAGTGTT AGATGAGCTA CAACATTATT GTCATGGACT AGAGAGCAGA 300

CGACTTAGAA AATACCTCTT CCAGATTCTT CGAGCAATTG ATTATCTTCA CACTAATAAT 360

ATCATCCATC GAGATATAAA ACCTGAGAAT ATTTTAGTAT CTCAATCAGG AGTTACTAAA 420

CTCTGCGATT TTGGTTTTGC ACGAACGCTA GCGGCTCCTG GAGACATTTA TACAGACTAT 480

GTGGCCACAC GCTGGTACAG AGCTCCAGAA TTAGTATTAA AAGATACCTC TTATGGAAAG 540

AAGCCCACAG AAATTTGGTT GAAAGGATAC CTTAGTGGCA TCCTATACTC TGGGCACCTA 600

TTCCTGATTG ATATGGAAAA GCTAATTTTC ATGGAAAAGT TAGTTTTAGT TGTTGGTTTT 660

ACTACCTTCC ACCTACATGA AGGGAAAACC AGTTTTAAAC TAAAGACTCT TTTTGTAGGT 720

CTTTTCATTA AGAGGCTGAG AGCCTGGAAA ACTAGCAAAC ACAAATATTA TGTTTTGCCT 780

TCTTTTAGAG GAAGAATTAA AATTATAAAG CAAGCTTGTT TACAAATTGA TCCTGATGAG 840

AGGATATCAA CTACTGATCT TTTGCATCAT GAGTATTTTA CCAGAGATGG ATTTATTGAA 900

AAATTCATAC CAGAACTGAG AGCTAAATTG CTACAAGAAG CAAAAGTCAA CTCATTCATA 960

AAGCCAAAAG GAAATTCTAA AGAAAATGAA CTTATGAAAG ATGAAAGAAA AACAATTTAT 1020

ACCAATACCC TGCTAAGTAA TTCAGTTTGG GGAAAGGAAG TGGAAAAAGA GAAAAAGCCC 1080

AAGGAGATCA AAGTGAGAGT TATTAAAGTT AGAGGAGGAA AAGGAGATGT CTTAGAACCA 1140

AAGAAGACAG AGCATGAAGG TGCACATTGT CAACAGGATG CGGTTGAAAT TGCTCACACT 1200

GTGTCTCAAG ATGCAAACAT CAGTGATCCA CTAAATCCTC TCAATCCCAG CACTAACTCT 1260

ACGGGCATGA AAGACGATCC ACATGCTGGA GGTAGTATGG TGATGCCACC CATCAATCTA 1320

ACCAGCAGTA ATTTGATGGC TTCAAATCCC AGTTCAAATC CCTCCCACTC TCATTCAAGG 1380

TTAAGTGAAA GAGCAAAAAA GAGGCGTACT TCTTCACAAT TTGTTGGACA AGTTATGTCT 1440

AATAGCAAGC ATGAGAATAC AGGTCCCTCT CAAGTAAGCC AAATGGAGAA GAGTGCATTT 1500

AATGATCGAA CAGGTCCAAG TGACCAAATG GCAAATGGAA ACAAAAGGAA GCTGAATTTT 1560

TCCAGATTTG AAAGGAAAGA ATTCCATTTT CCAGAATTGC CTTTCATAAT ACCGTCAAAG 1620

GAGATGAAAG GAATGGAAGT TAAACAGATA AAAGTTTTGA AGAAGGAATC AAAGAAAATT 1680

AATTCATCTA AAATACCAAC TTTACTTAAT GCAGATCAAT ATCAAGAAAA AGAAGAGGTA 1740

AAACTTTTTG TTTATAGCTT TTACTAA 1767

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc+ kdtgqivaik f+e+++ k+v+kia+reik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKRKDTGQIVAIKIFYEKPE-KSVNKIATREIKFLKQFRHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+tvldel++y++G+e+++++k+l+qil+ai+++h+nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESRRLRKYLFQILRAIDYLHTNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGk.s  179

         hrdikpenil+s+sgv+klcdfGfar+laapgd+ytdyvatrwyrapel+++dt+yGk +

Q: 123   HRDIKPENILVSQSGVTKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKkP  182

         *********************************************************648

S: 180   vdvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprh...qkifsknevfaGvk  236

          ++w  G l   l +G+ ++    ++  + k++ ++G  + +    +  f+ + +f G+

Q: 183   TEIWLKGYLSGILYSGHLFLIDMEKLIFMEKLVLVVGFTTFHLhegKTSFKLKTLFVGLF  242

         9*******************99999999999999999765544111568***********

S: 237   lpevedleslekkypklnev..lldllk.kclkldpaerlsceellkheyf  284

         + + +  ++ ++ky  l +    ++++k +cl++dp+er+s+++ll+heyf

Q: 243   IKRLRAWKTSKHKYYVLPSFrgRIKIIKqACLQIDPDERISTTDLLHHEYF  293

         **************9776642256766527********************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKR KDTGQIVAIK IFYEKPEKSV NKIATREIKF LKQFRHENLV 60

NLIEVFRQKK KIHLVFEFID HTVLDELQHY CHGLESRRLR KYLFQILRAI DYLHTNNIIH 120

RDIKPENILV SQSGVTKLCD FGFARTLAAP GDIYTDYVAT RWYRAPELVL KDTSYGKKPT 180

EIWLKGYLSG ILYSGHLFLI DMEKLIFMEK LVLVVGFTTF HLHEGKTSFK LKTLFVGLFI 240

KRLRAWKTSK HKYYVLPSFR GRIKIIKQAC LQIDPDERIS TTDLLHHEYF 290

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013